Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Stroke D020521 32 associated lipids
Hypothyroidism D007037 32 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Proteinuria D011507 30 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Kidney Diseases D007674 29 associated lipids
Endometriosis D004715 29 associated lipids
Ventricular Remodeling D020257 28 associated lipids
Gastritis D005756 27 associated lipids
Endotoxemia D019446 27 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Singh D et al. Evidence for the generation of hydroxyl radical during arachidonic acid metabolism by human platelets. 1981 Am. J. Hematol. pmid:6274189
Smith EF and Lefer AM Stabilization of cardiac lysosomal and cellular membranes in protection of ischemic myocardium due to coronary occlusion:efficacy of the nonsteroidal anti-inflammatory agent, naproxen. 1981 Am. Heart J. pmid:7211667
Shaw JO et al. Activation of rabbit platelet phospholipase and thromboxane synthesis by 1-O-hexadecyl/octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (platelet activating factor). 1981 Biochim. Biophys. Acta pmid:7213765
Kass MA et al. Prostaglandin and thromboxane synthesis by microsomes of inflamed rabbit ciliary body--iris. 1981 Invest. Ophthalmol. Vis. Sci. pmid:7216665
Okamatsu S et al. Effect of calcium channel blockers on arachidonate-induced sudden death in rabbits. 1981 Proc. Soc. Exp. Biol. Med. pmid:6261265
Rao GH et al. Modification of human platelet response to sodium arachidonate by membrane modulation. 1981 Prostaglandins Med pmid:6261286
di Minno G et al. Effects of any epoxymethano stable analogue of prostaglandin endoperoxides (U-46619) on human platelets. 1981 Thromb. Haemost. pmid:6266066
Handler JS Vasopressin-prostaglandin interactions in the regulation of epithelial cell permeability to water. 1981 Kidney Int. pmid:6267350
Best LC et al. Strontium ions induce production of thromboxane B2 and secretion of 5-hydroxytryptamine in washed human platelets. 1981 Biochem. Pharmacol. pmid:6268118
Roy AC et al. Effect of intravenous infusion of OKY-1581 (sodium-(E)-3-[4-(3-pyridylmethyl)phenyl] -2-methylacrylate) on circulatory thromboxane A2 and prostacyclin levels in anaesthetized baboon. 1981 Prostaglandins Med pmid:7029585
Stuart MJ Effect of endotoxin on arachidonic acid release and thromboxane B2 production by human platelets. 1981 Am. J. Hematol. pmid:7030066
Dembélé-Duchesne MJ et al. Some new prospects in the mechanism of control of arachidonate metabolism in human placenta and amnion. 1981 Prostaglandins pmid:6801732
Lorenz R et al. Effects of very low versus standard dose acetyl salicylic acid, dipyridamole and sulfinpyrazone on platelet function and thromboxane formation in man. 1981 Eur. J. Pharmacol. pmid:7238575
Polley MJ et al. Human complement in the arachidonic acid transformation pathway in platelets. 1981 J. Exp. Med. pmid:7241047
Greenberg S et al. Pulmonary vascular smooth muscle function in porcine splanchnic arterial occlusion shock. 1981 Am. J. Physiol. pmid:7246787
Townsend ER et al. Preservation of platelets during extracorporeal circulation in sheep. A comparison between aspirin and sulfinpyrazone. 1981 Circ. Res. pmid:7249281
McCann DS et al. Radioimmunoassay for plasma thromboxane B2. 1981 Clin. Chem. pmid:7273401
Allen JB et al. Irradiation decreases vascular prostacyclin formation with no concomitant effect on platelet thromboxane production. 1981 Lancet pmid:6118629
Anderson CB et al. Thromboxane-B2 and renovascular resistance during hypothermic pulsatile perfusion. 1981 Transplant. Proc. pmid:7268892
Bishai I and Coceani F Transformations of prostaglandin H2 in the cat brain. 1981 Biochim. Biophys. Acta pmid:6894549
Drake TS et al. Peritoneal fluid thromboxane B2 and 6-keto-prostaglandin F1 alpha in endometriosis. 1981 Am. J. Obstet. Gynecol. pmid:6894667
Halushka PV et al. Protective effects of aspirin in endotoxic shock. 1981 J. Pharmacol. Exp. Ther. pmid:6894770
Feuerstein N et al. Leukotrienes C4 and D4 induce prostaglandin and thromboxane release from rat peritoneal macrophages. 1981 Br. J. Pharmacol. pmid:6894882
Karmazyn M et al. Comparative effects of acetylsalicylic acid (ASA) and sulfinpyrazone on isoproterenol-induced heart damage. 1981 J. Pharmacol. Exp. Ther. pmid:6894943
Morrison AR and Benabe JE Prostaglandins in vascular tone in experimental obstructive nephropathy. 1981 Kidney Int. pmid:6894950
Bombardieri S et al. The synovial prostaglandin system in chronic inflammatory arthritis: differential effects of steroidal and nonsteroidal anti-inflammatory drugs. 1981 Br. J. Pharmacol. pmid:6895043
Defreyn G et al. Familial bleeding tendency with partial platelet thromboxane synthetase deficiency: reorientation of cyclic endoperoxide metabolism. 1981 Br. J. Haematol. pmid:6268139
Prancan A et al. Platelet thromboxane production during endotoxin shock. 1981 Agents Actions pmid:7340458
Hwang DH Characteristics of the aggregation of platelets and the formation of prostaglandins (PGs) in rat. 1981 Prog. Lipid Res. pmid:7342108
Halushka PV et al. Increased platelet thromboxane synthesis in diabetes mellitus. 1981 J. Lab. Clin. Med. pmid:7452084
Laviolette M et al. Human alveolar macrophages: a lesion in arachidonic acid metabolism in cigarette smokers. 1981 Am. Rev. Respir. Dis. pmid:6794395
Grimm LJ et al. Inhibition of platelet thromboxane synthesis by 7-(1-imidazolyl) heptanoic acid: dissociation from inhibition of aggregation. 1981 Thromb. Res. pmid:6801806
Honn KV and Meyer J Thromboxanes and prostacyclin: positive and negative modulators of tumor growth. 1981 Biochem. Biophys. Res. Commun. pmid:6274330
Igarashi K et al. Effect of polyamines on prostaglandin synthesis in various cell-free systems. 1981 Biochem. Biophys. Res. Commun. pmid:6800368
Landgraf-Leurs MM et al. Aggregation and thromboxane B2 formation in platelets and vascular prostacyclin production from genetically obese rats. 1981 Prostaglandins pmid:6798637
Tsuboi T et al. Effect of gliclazide on prostaglandin and thromboxane synthesis in guinea-pig platelets. 1981 Jan 1-15 Thromb. Res. pmid:7233394
Randall MJ et al. UK-37, 248, a novel, selective thromboxane synthetase inhibitor with platelet anti-aggregatory and anti-thrombotic activity. 1981 Jul 1-15 Thromb. Res. pmid:6795753
Kelton JG et al. Sex-related differences in the efficacy of acetylsalicylic acid (ASA) : the absorption of ASA and its effect on collagen-induced thromboxane B2 generation. 1981 Oct 1-15 Thromb. Res. pmid:7330835
Fitzpatrick FA A radioimmunoassay for thromboxane B2. 1982 Meth. Enzymol. pmid:7132759
Martin JF et al. Effect of acetylsalicylic acid on platelet aggregation and thromboxane B2 production in flowing aortic blood in the rat studied with a filter loop technique. 1982 Thromb. Res. pmid:6814004
Dorsch W et al. Mediator studies in skin blister fluid from patients with dual skin reactions after intradermal allergen injection. 1982 J. Allergy Clin. Immunol. pmid:6181112
Numano F et al. Effects of thromboxane A2 injection on the rabbit coronary artery. II. The production of infarcts in cholesterol-fed animals. 1982 Exp. Mol. Pathol. pmid:6956517
Goldsmith JC and Needleman SW A comparative study of thromboxane and prostacyclin release from ex vivo and cultured bovine vascular endothelium. 1982 Prostaglandins pmid:6815717
Blackwell GJ et al. Prostacyclin prolongs viability of washed human platelets. 1982 Biochim. Biophys. Acta pmid:6291622
Jaweed MM et al. Changes in thromboxane B2 and 6-keto-PGF1 alpha after direct electrical stimulation of the denervated rat gastrocnemius1,2. 1982 Prostaglandins Leukot Med pmid:6956927
Taube C et al. Enhanced thromboxane production in the aorta of spontaneously hypertensive rats in vitro. 1982 Prostaglandins Leukot Med pmid:6960370
Castaldi PA et al. Evidence for a platelet membrane defect in the myeloproliferative syndromes. 1982 Thromb. Res. pmid:6960545
Kelley VE et al. Effect of ibuprofen, a fatty acid cyclooxygenase inhibitor, on murine lupus. 1982 Clin. Immunol. Immunopathol. pmid:6819912
Miller JL et al. Arachidonic acid metabolism in guinea pig megakaryocytes. 1982 Biochem. Biophys. Res. Commun. pmid:6812584
Robinson C et al. Thromboxane B2 uptake and metabolism in isolated perfused lung. Identification and comparison with prostaglandin F2 alpha. 1982 Biochim. Biophys. Acta pmid:6751406