Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

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What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with Thromboxane b2?

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What functions are associated with Thromboxane b2?


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What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

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What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

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Authors Title Published Journal PubMed Link
Simmons PM et al. The release of leukotriene B4 during experimental inflammation. 1983 Biochem. Pharmacol. pmid:6305369
Svensson J and Samuelsson K Inhibition of platelet function by low dose acetylsalicylic acid in patients with cerebrovascular disease. 1983 Thromb. Res. pmid:20218005
Johnsen SA et al. Conversion of arachidonic acid in human maternal and neonatal mononuclear leukocytes. 1983 Immunol. Lett. pmid:6411611
Nordøy A et al. Platelets and coagulation in patients with familial hypercholesterolemia (type IIa). 1983 Acta Med Scand pmid:6188328
Roth DM et al. Protective actions of ibuprofen in arachidonate-induced sudden death. 1983 Pharmacology pmid:6413987
Salmon JA et al. Synthesis of arachidonate cyclo-oxygenase products by rheumatoid and nonrheumatoid synovial lining in nonproliferative organ culture. 1983 Ann. Rheum. Dis. pmid:6402992
Harlan J et al. Selective inhibition of thromboxane synthesis during experimental endotoxemia in the goat: effects on pulmonary haemodynamics and lung lymph flow. 1983 Br J Clin Pharmacol pmid:6337602
Ball HA et al. Effect of dazoxiben, a specific inhibitor of thromboxane synthetase, on acute pulmonary responses to E. coli endotoxin in anaesthetized cats. 1983 Br J Clin Pharmacol pmid:6337603
Dodd NJ et al. Use of a thromboxane synthetase inhibitor, dazoxiben, during haemodialysis. 1983 Br J Clin Pharmacol pmid:6337605
Di Minno G et al. Exposure of platelet fibrinogen-binding sites by collagen, arachidonic acid, and ADP: inhibition by a monoclonal antibody to the glycoprotein IIb-IIIa complex. 1983 Blood pmid:6216929
Ylikorkala O et al. Maternal prostacyclin, thromboxane, and placental blood flow. 1983 Am. J. Obstet. Gynecol. pmid:6338724
Williams GA et al. Prostacyclin and thromboxane A2 derivatives in rhegmatogenous subretinal fluid. 1983 Arch. Ophthalmol. pmid:6338873
Ylikorkala O et al. Effect of vacuum curettage on the concentrations of plasma 6-keto-prostaglandin F1 alpha and serum thromboxane B2. 1983 Br J Obstet Gynaecol pmid:6338904
Marcella JJ et al. Exercise-induced myocardial ischemia in patients with coronary artery disease: lack of evidence for platelet activation or fibrin formation in peripheral venous blood. 1983 J. Am. Coll. Cardiol. pmid:6339591
Brox JH et al. Effects of cod liver oil on platelets and coagulation in familial hypercholesterolemia (type IIa). 1983 Acta Med Scand pmid:6340424
Vlasses PH et al. Urinary excretion of prostacyclin and thromboxane A2 metabolites after angiotensin converting enzyme inhibition in hypertensive patients. 1983 Prostaglandins Leukot Med pmid:6308685
Huval WV et al. Thromboxane mediation of cardiovascular dysfunction following aspiration. 1983 Surgery pmid:6308843
Hartung HP Acetyl glyceryl ether phosphorylcholine (platelet-activating factor) mediates heightened metabolic activity in macrophages. Studies on PGE, TXB2 and O2- production, spreading, and the influence of calmodulin-inhibitor W-7. 1983 FEBS Lett. pmid:6309563
Sheng WY et al. Kinetic comparison and regulation of the cascade of microsomal enzymes involved in renal arachidonate and endoperoxide metabolism. 1983 J. Biol. Chem. pmid:6401732
Chetty N and Bradlow BA The effects of a vegetarian diet on platelet function and fatty acids. 1983 Thromb. Res. pmid:6612688
Parry MJ Effects of thromboxane synthetase inhibition on arachidonate metabolism and platelet behaviour. 1983 Br J Clin Pharmacol pmid:6401997
Ujiie A et al. [Studies on the inhibitory effect of etafenone hydrochloride on platelet aggregation]. 1983 Nippon Yakurigaku Zasshi pmid:6618341
Kawaguchi H Thromboxane synthesis in hypercholesterolemic platelets--on the mechanism of increased thromboxane synthesis. 1983 Hokkaido Igaku Zasshi pmid:6618425
Jakubowski JA et al. Arachidonic acid metabolism by platelets of differing size. 1983 Br. J. Haematol. pmid:6402003
Dubin NH et al. Thromboxane production in the pregnant rat: differential recovery by platelets and uterus following aspirin administration. 1983 Biol. Reprod. pmid:6626652
Krishnamurthi S et al. Paradoxical effects of indomethacin and trifluoperazine on Ca2+ ionophore A23187-induced human platelet aggregation, thromboxane B2 production, and dense granule release. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221559
Lecompte T et al. Interference of transmethylation inhibitors with thromboxane synthesis in rat platelets: evidence for the requirement of a methyl transfer reaction in platelet activation. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221560
Patrono C et al. Evidence for a renal origin of urinary thromboxane B2 in health and disease. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221569
Fletcher JR et al. Thromboxane inhibition in gram-negative sepsis fails to improve survival. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221586
Socini A et al. Fish oil administration lowers prostacyclin production and the antiaggregatory activity of aortic walls more effectively than platelet aggregation and thromboxane in the rat. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221591
Hornstra G et al. Dietary-fat-induced changes in the formation of prostanoids of the 2 and 3 series in relation to arterial thrombosis (rat) and atherosclerosis (rabbit). 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221593
Tremoli E et al. North Karelian study: changes in dietary fat reduce thromboxane B2 formation by platelets only in male subjects--preliminary report. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221594
Basso N et al. Gastric mucosal prostaglandin generation in rats with stress ulcer. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221618
Sinzinger H and Firbas W [Cells of the vascular wall synthesize thromboxane]. 1983 Wien. Klin. Wochenschr. pmid:6369802
Mehta P et al. Inhibitory effects of diltiazem on platelet activation caused by ionophore A23187 plus ADP or epinephrine in subthreshold concentrations. 1983 J. Lab. Clin. Med. pmid:6411841
Gordon PR et al. Platelet arachidonate metabolism and platelet function in zinc-deficient rats. 1983 J. Nutr. pmid:6403678
Okegawa T et al. Endotoxin induces chronic prostaglandin and thromboxane synthesis from ureter-obstructed kidneys: role of inflammatory cells. 1983 J. Pharmacol. Exp. Ther. pmid:6403696
Ellsworth ML et al. Pulmonary prostacyclin production with increased flow and sympathetic stimulation. 1983 J Appl Physiol Respir Environ Exerc Physiol pmid:6415017
Dahl ML et al. Sodium salicylate interferes with the inhibitory effects of aspirin and indomethacin on human platelets. 1983 Prostaglandins Leukot Med pmid:6415666
Tsukatani E Etiology of EPH-gestosis from the viewpoint of dynamics of vasoactive prostanoid, lipid peroxides and vitamin E. 1983 Nippon Sanka Fujinka Gakkai Zasshi pmid:6688085
Han P et al. Verapamil and collagen-induced platelet reactions--evidence for a role for intracellular calcium in platelet activation. 1983 Thromb. Haemost. pmid:6415847
Fischer S et al. In vivo and in vitro effects of nafazatrom (Bay g 6575), an antithrombotic compound, on arachidonic acid metabolism in platelets and vascular tissue. 1983 Biochem. Pharmacol. pmid:6688182
Barnhart MI et al. DDAVP: does the drug have a direct effect on the vessel wall? 1983 Thromb. Res. pmid:6415852
Bailey IA et al. Effects of vascular trauma and transient myocardial ischaemia on coronary venous prostaglandin levels in the dog. 1983 Cardiovasc. Res. pmid:6688202
Srivastava KC and Awasthi KK Separation and quantitative determination of radiolabeled prostaglandins, thromboxanes, 6-keto-prostaglandin F1 alpha and other arachidonic acid metabolites produced in biological material. 1983 J. Chromatogr. pmid:6688256
Wilson L and Huang LS Effects of the fetal-placental unit on uterine prostaglandin levels at term in the pregnant rat. 1983 Prostaglandins pmid:6688474
Saldeen P and Saldeen T 6-keto-prostaglandin F1 alpha/thromboxane B2 ratio in vascular and lung tissue. 1983 Thromb. Res. pmid:6688484
Wilson TW Responses to furosemide in normotensive and hypertensive subjects. 1983 Clin. Pharmacol. Ther. pmid:6688772
Gurtner GH et al. Oxidant- and lipid-induced pulmonary vasoconstriction mediated by arachidonic acid metabolites. 1983 J Appl Physiol Respir Environ Exerc Physiol pmid:6688802
van Rijk GL et al. Long-term myocardial preservation: thromboxane production and coronary resistance. 1983 J. Surg. Res. pmid:6688844
Hidaka T et al. Thromboxane formation from arachidonic acid and prostaglandin H2 in rabbit spleen. 1983 J. Biochem. pmid:6404897
Gerozissis K and Dray F In-vitro prostanoid production by the rat vas deferens. 1983 J. Reprod. Fertil. pmid:6572721
Okahara T et al. Zonal heterogeneity of prostaglandin and thromboxane release in the dog kidney. 1983 Prostaglandins pmid:6575405
Hoult JR and Robinson C Selective inhibition of thromboxane B2 accumulation and metabolism in perfused guinea-pig lung. 1983 Br. J. Pharmacol. pmid:6824820
Hirsh PD et al. Effects of provocation on transcardiac thromboxane in patients with coronary artery disease. 1983 Am. J. Cardiol. pmid:6829431
Walinsky P et al. Beneficial effects of ibuprofen in pacing-induced myocardial ischemia. 1983 Am. J. Cardiol. pmid:6829434
Roy L et al. Increased plasma concentrations of prostacyclin metabolite 6-keto-PGF1 alpha in essential hypertension. Influence of therapy with labetalol. 1983 Am. J. Cardiol. pmid:6823861
Rojas J et al. Effects of cyclooxygenase inhibition on the response to group B streptococcal toxin in sheep. 1983 Pediatr. Res. pmid:6402752
Förster W and Pönicke K Influence of sympathomimetic drugs (1-phenyl-2-amino-ethan-1-ol derivatives) on the biosynthesis of prostaglandins and thromboxane B2. 1983 Br. J. Pharmacol. pmid:6403094
Nenci GG et al. Platelet malondialdehyde production kinetics after cyclooxygenase block. A study performed with a modified high sensitivity assay. 1983 Haemostasis pmid:6404715
Lewy RI Role of thromboxanes in vasotonic versus vaso-occlusive angina. 1983 Arch Mal Coeur Vaiss pmid:6407435
Hayashi Y et al. Enzyme immunoassay of thromboxane B2. 1983 Biochim. Biophys. Acta pmid:6407530
Poyser NL and Brydon LJ Prostaglandin release from the guinea-pig uterus superfused in vitro. Effect of stage of estrous cycle, progesterone, estradiol, oxytocin and A23187. 1983 Prostaglandins pmid:6408712
Butler RR et al. Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production. 1983 J. Pharmacol. Exp. Ther. pmid:6339712
Laitinen O et al. Plasma levels and urinary excretion of prostaglandins in patients with rheumatoid arthritis. 1983 Clin. Rheumatol. pmid:6589104
Ouwendijk RJ et al. Raised plasma levels of thromboxane B2 in systemic mastocytosis. 1983 Eur. J. Clin. Invest. pmid:6409646
Snapper JR et al. Effects of cyclooxygenase inhibitors on the alterations in lung mechanics caused by endotoxemia in the unanesthetized sheep. 1983 J. Clin. Invest. pmid:6409930
Asbóth G et al. Conversion of arachidonic acid to prostanoids in the avian uterus. 1983 Biochim. Biophys. Acta pmid:6402032
Rao GH et al. Ibuprofen protects platelet cyclooxygenase from irreversible inhibition by aspirin. 1983 Jul-Aug Arteriosclerosis pmid:6411052
Konieczkowski M et al. Glomerular synthesis of prostaglandins and thromboxane in spontaneously hypertensive rats. 1983 Jul-Aug Hypertension pmid:6407990
Stuart MJ The effect of irradiation on platelet arachidonic acid metabolism. 1983 Mar-Apr Transfusion pmid:6404019
Newman WH et al. Increased myocardial release of prostacyclin in dogs with heart failure. 1983 Mar-Apr J. Cardiovasc. Pharmacol. pmid:6188889
Coker SJ and Parratt JR Nifedipine reduces arrhythmias but does not alter prostanoid release during coronary artery occlusion and reperfusion in anaesthetised greyhounds. 1983 May-Jun J. Cardiovasc. Pharmacol. pmid:6191139
Peskar BM Effects of carbenoxolone on the gastric mucosal prostaglandin and thromboxane system. 1983 Sep-Oct Acta Gastroenterol. Belg. pmid:6324520
Burke SE et al. Protection of ischemic cat myocardium by CGS-13080, a selective potent thromboxane A2 synthesis inhibitor. 1983 Sep-Oct J. Cardiovasc. Pharmacol. pmid:6195474
Deimann W et al. Endogenous peroxidase in the nuclear envelope and endoplasmic reticulum of human monocytes in vitro: association with arachidonic acid metabolism. 1984 Blood pmid:6331550
Kopolovic R et al. Effects of ibuprofen on a porcine model of acute respiratory failure. 1984 J. Surg. Res. pmid:6708494
Stahl RA et al. Angiotensin II stimulation of prostaglandin E2 and 6-keto-F1 alpha formation by isolated human glomeruli. 1984 Kidney Int. pmid:6592393
Nagashima Y et al. [The effects of hog pancreatic kallikrein on the plasma kinins-prostaglandins and renin-angiotensin-aldosterone systems]. 1984 Nihon Naibunpi Gakkai Zasshi pmid:6097484
Ylikorkala O et al. Maternal thromboxane, prostacyclin, and umbilical blood flow in humans. 1984 Obstet Gynecol pmid:6546976
Hwang DH et al. Zinc deficiency affects neither platelet arachidonic acid metabolism nor platelet aggregation in rats. 1984 J. Nutr. pmid:6582232
Navran SS et al. Human platelet activation by bacterial phospholipase C is mediated by phosphatidylinositol hydrolysis but not generation of phosphatidic acid: inhibition by a selective inhibitor of phospholipase C. 1984 Thromb. Res. pmid:6372157
Vicenzi E et al. Human mononuclear phagocytes from different anatomical sites differ in their capacity to metabolize arachidonic acid. 1984 Clin. Exp. Immunol. pmid:6432383
Nichols AB et al. Effect of heparin bonding on catheter-induced fibrin formation and platelet activation. 1984 Circulation pmid:6237807
Sicard GA et al. Prostaglandin production and platelet reactivity of small-diameter grafts. 1984 J. Vasc. Surg. pmid:6238179
Goodman MG and Weigle WO Regulation of B-lymphocyte proliferative responses by arachidonate metabolites: effects on membrane-directed versus intracellular activators. 1984 J. Allergy Clin. Immunol. pmid:6432883
Zammit M et al. Aspirin therapy in small-caliber arterial prostheses: long-term experimental observations. 1984 J. Vasc. Surg. pmid:6238183
Klaverkamp J and Völkl KP Maintenance of platelet viability after platelet-labeling with fluorescein isothiocyanate. 1984 Haemostasis pmid:6238881
Koike K et al. Platelet secretion defect in patients with the attention deficit disorder and easy bruising. 1984 Blood pmid:6692042
Vesterqvist O et al. Development of a GC-MS method for quantitation of 2,3-dinor-TxB2 and determinations of the daily urinary excretion rates in healthy humans. 1984 Thromb. Res. pmid:6695361
Davì G et al. Platelet function changes in acute myocardial infarction. 1984 Adv. Exp. Med. Biol. pmid:6695571
Goldyne ME Heterogeneity in leukocyte preparations: effects on defining eicosanoid metabolism by human lymphocytes and monocytes. 1984 J. Allergy Clin. Immunol. pmid:6088610
Pickard JD et al. Arterial eicosanoid production following chronic exposure to a periarterial haematoma. 1984 J. Neurol. Neurosurg. Psychiatr. pmid:6589362
Roth DM et al. Effects of lipoxygenase inhibitors in arachidonate-induced sudden death. 1984 J. Pharm. Pharmacol. pmid:6144761
Mahmud I et al. Thromboxane synthesizing system in rat liver. 1984 Prostaglandins Leukot Med pmid:6597457
Burch RM and Halushka PV Alterations in extracellular calcium concentration differentially influence prostaglandin and thromboxane synthesis in epithelial cells from the toad urinary bladder. 1984 Arch. Biochem. Biophys. pmid:6422855
Crutchley DJ Effects of inhibitors of arachidonic acid metabolism on thromboplastin activity in human monocytes. 1984 Biochem. Biophys. Res. Commun. pmid:6422935
Galli C et al. Acute effects of ethanol, caffeine, or both on platelet aggregation, thromboxane formation, and plasma-free fatty acids in normal subjects. 1984 Drug Nutr Interact pmid:6510241
Lelcuk S et al. Inhibition of ischemia-induced thromboxane synthesis in man. 1984 J Trauma pmid:6325720
Swart SS et al. Functional significance of the platelet alpha2-adrenoceptor: studies in patients with myeloproliferative disorders. 1984 Thromb. Res. pmid:6326344