Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Thrombocytopenia D013921 15 associated lipids
Thrombocythemia, Essential D013920 9 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Thrombasthenia D013915 4 associated lipids
Takayasu Arteritis D013625 3 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Tachycardia, Paroxysmal D013614 2 associated lipids
Tachycardia D013610 7 associated lipids
Subarachnoid Hemorrhage D013345 17 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Ylikorkala O et al. Amniotic fluid prostacyclin and thromboxane in normal, preeclamptic, and some other complicated pregnancies. 1981 Am. J. Obstet. Gynecol. pmid:6895277
Nelson DM et al. Hypoxia limits differentiation and up-regulates expression and activity of prostaglandin H synthase 2 in cultured trophoblast from term human placenta. 1999 Am. J. Obstet. Gynecol. pmid:10203658
Moutquin JM et al. Do prostacyclin and thromboxane contribute to the "protective effect" of pregnancies with chronic hypertension? A preliminary prospective longitudinal study. 1997 Am. J. Obstet. Gynecol. pmid:9423755
Fantone JC et al. Stimulus specificity of prostaglandin inhibition of rabbit polymorphonuclear leukocyte lysosomal enzyme release and superoxide anion production. 1984 Am. J. Pathol. pmid:6324595
Cybulsky AV et al. A role for thromboxane in complement-mediated glomerular injury. 1987 Am. J. Pathol. pmid:3111267
Zoja C et al. Selective inhibition of platelet thromboxane generation with low-dose aspirin does not protect rats with reduced renal mass from the development of progressive disease. 1989 Am. J. Pathol. pmid:2497648
Lundberg C et al. C5a-induced hemodynamic and hematologic changes in the rabbit. Role of cyclooxygenase products and polymorphonuclear leukocytes. 1987 Am. J. Pathol. pmid:3115110
Stimler NP and O'Flaherty JT Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues. 1983 Am. J. Pathol. pmid:6624879
Woods LW et al. Structural and biochemical changes in lungs of 3-methylindole-treated rats. 1993 Am. J. Pathol. pmid:8424451
Diamond JR et al. Altered functional characteristics of rat macrophages during nephrosis. Synergistic effects of hypercholesterolemia. 1989 Am. J. Pathol. pmid:2801885
Cook HT et al. Functional characteristics of macrophages in glomerulonephritis in the rat. O2- generation, MHC class II expression, and eicosanoid synthesis. 1989 Am. J. Pathol. pmid:2537019
Mundie TG et al. Byssinosis: Release of prostaglandins, thromboxane, and 5-hydroxytryptamine in bronchopulmonary lavage fluid after inhalation of cotton dust extracts. 1985 Am. J. Pathol. pmid:3966532
Bertani T et al. Tumor necrosis factor induces glomerular damage in the rabbit. 1989 Am. J. Pathol. pmid:2916653
Hamilton J et al. Platelet interaction with a pancreatic ascites tumor. 1986 Am. J. Pathol. pmid:3510553
Nanji AA et al. Severity of liver injury in experimental alcoholic liver disease. Correlation with plasma endotoxin, prostaglandin E2, leukotriene B4, and thromboxane B2. 1993 Am. J. Pathol. pmid:8382006
Yamamoto S et al. Endothelin causes portal and pulmonary hypertension in porcine endotoxemic shock. 1997 Am. J. Physiol. pmid:9087598
Strand JC et al. Effect of imidazole on renal function in unilateral ureteral-obstructed rat kidneys. 1981 Am. J. Physiol. pmid:6787931
Widdicombe JH et al. Release of cyclooxygenase products from primary cultures of tracheal epithelia of dog and human. 1989 Am. J. Physiol. pmid:2514604
Vanderhoof JA et al. Reduced mucosal prostaglandin synthesis after massive small bowel resection. 1988 Am. J. Physiol. pmid:3279815
Coceani F et al. Further evidence implicating prostaglandin E2 in the genesis of pyrogen fever. 1988 Am. J. Physiol. pmid:3279826
Del Maschio A et al. Platelet activation by polymorphonuclear leukocytes exposed to chemotactic agents. 1990 Am. J. Physiol. pmid:2156456
Perlman MB et al. Ibuprofen prevents thrombin-induced lung vascular injury: mechanism of effect. 1987 Am. J. Physiol. pmid:3030141
Schlondorff D and Satriano JA Interactions of vasopressin, cAMP, and prostaglandins in toad urinary bladder. 1985 Am. J. Physiol. pmid:2579584
Barnard JW et al. Sustained effects of endothelin-1 on rabbit, dog, and rat pulmonary circulations. 1991 Am. J. Physiol. pmid:1877674
Adler S et al. Biphasic effect of oxygen radicals on prostaglandin production by rat mesangial cells. 1987 Am. J. Physiol. pmid:3105332
Cudd TA and Wood CE Thromboxane A2 receptor antagonism prevents hormonal and cardiovascular responses to mineral acid infusion. 1994 Am. J. Physiol. pmid:7977850
Leffler CW and Busija DW Prostanoids and pial arteriolar diameter in hypotensive newborn pigs. 1987 Am. J. Physiol. pmid:3551632
Del Balzo U et al. Complement C5a-mediated myocardial ischemia and neutrophil sequestration: two independent phenomena. 1993 Am. J. Physiol. pmid:8447449
Klausner JM et al. Postischemic renal injury is mediated by neutrophils and leukotrienes. 1989 Am. J. Physiol. pmid:2541628
Chakraborti S et al. Oxidant-mediated activation of phospholipase A2 in pulmonary endothelium. 1989 Am. J. Physiol. pmid:2514605
McGowan HM et al. Dexamethasone attenuates reversal of hypertension in one-kidney, one-clip rats. 1988 Am. J. Physiol. pmid:3177664
Garfield RE et al. Gap junction formation in myometrium: control by estrogens, progesterone, and prostaglandins. 1980 Am. J. Physiol. pmid:7369350
Nukina S et al. Glycogenolytic effect of adenosine involves ATP from hepatocytes and eicosanoids from Kupffer cells. 1994 Am. J. Physiol. pmid:8304463
Grimminger F et al. Differential influence of arachidonic vs. eicosapentaenoic acid on experimental pulmonary hypertension. 1995 Am. J. Physiol. pmid:7611475
Kalichman MW et al. Effects of cocaine on blood flow and prostaglandin metabolites in rat sciatic nerve. 1994 Am. J. Physiol. pmid:8024013
Teitelbaum I et al. Effect of cAMP on prostaglandin E2 production in cultured rat inner medullary collecting tubule cells. 1986 Am. J. Physiol. pmid:3020997
Geisel J et al. Endotoxin tolerance is associated with decreased prostaglandin H synthases-1 and -2. 1994 Am. J. Physiol. pmid:7943269
Chen L et al. Cyclooxygenase inhibition decreases nitric oxide synthase activity in human platelets. 1997 Am. J. Physiol. pmid:9362253
Martin SE et al. Neuropeptide Y and coronary vasoconstriction: role of thromboxane A2. 1992 Am. J. Physiol. pmid:1415751
Beck N and Shaw JO Thromboxane B2 and prostaglandin E2 in the K+-depleted rat kidney. 1981 Am. J. Physiol. pmid:7468800
Don BR et al. Dietary protein intake modulates glomerular eicosanoid production in the rat. 1989 Am. J. Physiol. pmid:2539749
Podjarny E et al. Prostanoids in renal failure induced by converting enzyme inhibition in sodium-depleted rats. 1988 Am. J. Physiol. pmid:3162354
Perico N et al. Functional significance of exaggerated renal thromboxane A2 synthesis induced by cyclosporin A. 1986 Am. J. Physiol. pmid:3094383
Goldman G et al. Intravascular chemoattractants inhibit diapedesis by selective receptor occupancy. 1991 Am. J. Physiol. pmid:1847598
Prosdocimi M et al. Coronary and systemic 6-ketoprostaglandin F1 alpha and thromboxane B2 during myocardial ischemia in dog. 1985 Am. J. Physiol. pmid:3838623
Toda N et al. Comparison of hypoxia-induced contraction in human, monkey, and dog coronary arteries. 1992 Am. J. Physiol. pmid:1558175
Kauser K and Rubanyi GM Gender difference in bioassayable endothelium-derived nitric oxide from isolated rat aortae. 1994 Am. J. Physiol. pmid:7810731
Sirko S et al. Prostaglandin formation in the hypothalamus in vivo: effect of pyrogens. 1989 Am. J. Physiol. pmid:2784289
Brown GP and Venuto RC Eicosanoid production in rabbit vascular tissues and placentas. 1990 Am. J. Physiol. pmid:2316640
Jones SA et al. Eicosanoids in third ventricular cerebrospinal fluid of fetal and newborn sheep. 1993 Am. J. Physiol. pmid:8381613