Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Thrombocytopenia D013921 15 associated lipids
Thrombocythemia, Essential D013920 9 associated lipids
Thromboangiitis Obliterans D013919 4 associated lipids
Thrombasthenia D013915 4 associated lipids
Takayasu Arteritis D013625 3 associated lipids
Tachycardia, Supraventricular D013617 3 associated lipids
Tachycardia, Paroxysmal D013614 2 associated lipids
Tachycardia D013610 7 associated lipids
Subarachnoid Hemorrhage D013345 17 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Böhm E et al. 11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils. 2004 J. Biol. Chem. pmid:14668348
Persico N et al. Transdermal hormone replacement therapy and Doppler findings in normal and overweight postmenopausal patients. 2004 Gynecol. Endocrinol. pmid:15726916
He J et al. Treatment of unstable angina pectoris with modified nuan gan jian--a report of 33 cases. 2004 J Tradit Chin Med pmid:15688691
Arruzazabala ML et al. Effects of d-003, a new substance purified from sugar cane wax, on platelet aggregation and plasma levels of arachidonic acid metabolites in healthy volunteers. 2004 Int J Clin Pharmacol Res pmid:15689052
Kudolo GB et al. The ingestion of Ginkgo biloba extract (EGb 761) inhibits arachidonic acid-mediated platelet aggregation and thromboxane B2 production in healthy volunteers. 2004 J Herb Pharmacother pmid:15927922
Lam AN et al. Effect of red clover isoflavones on cox-2 activity in murine and human monocyte/macrophage cells. 2004 Nutr Cancer pmid:15456640
Xu L et al. [Effects of effective component from "qing kai ling" on endothelial cell of microvessel in MCAO rats]. 2004 Zhong Yao Cai pmid:15376390
Perneby C et al. Prothrombotic responses to exercise are little influenced by clopidogrel treatment. 2004 Thromb. Res. pmid:15381386
Hennekens CH et al. Terms and conditions: semantic complexity and aspirin resistance. 2004 Circulation pmid:15381661
Zhao GR et al. [Clinical study on relationship between sluggishness of lung-defensive qi and levels of vasoactive intestinal polypeptide and thromboxane B2]. 2004 Zhong Xi Yi Jie He Xue Bao pmid:15383251
Fiorucci S et al. Co-administration of nitric oxide-aspirin (NCX-4016) and aspirin prevents platelet and monocyte activation and protects against gastric damage induced by aspirin in humans. 2004 J. Am. Coll. Cardiol. pmid:15358033
Ming HX et al. [Influence of single leaf Asarum himalaicum on renal function of rabbits]. 2004 Zhong Xi Yi Jie He Xue Bao pmid:15339444
Dey A et al. Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria. 2004 Obes. Res. pmid:15340111
Sheu JR et al. Expression of matrix metalloproteinase-9 in human platelets: regulation of platelet activation in in vitro and in vivo studies. 2004 Br. J. Pharmacol. pmid:15289295
Toth B et al. Insights into the role of interleukin-6 in the induction of hepatic injury after trauma-hemorrhagic shock. 2004 J. Appl. Physiol. pmid:15298985
Devi MM and Das UN Effect of prostaglandins against alloxan-induced cytotoxicity to insulin secreting insulinoma RIN cells in vitro. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15380818
Korkushko OV et al. [Some mechanisms of the development of endothelial disfunction in aging]. 2004 Fiziol Zh pmid:15174205
Kawano T et al. Acetaldehyde induces histamine release from human airway mast cells to cause bronchoconstriction. 2004 Int. Arch. Allergy Immunol. pmid:15178893
Ishitsuka Y et al. Involvement of thromboxane A2 (TXA2) in the early stages of oleic acid-induced lung injury and the preventive effect of ozagrel, a TXA2 synthase inhibitor, in guinea-pigs. 2004 J. Pharm. Pharmacol. pmid:15099446
Dinev D and Andonova M The effect of general anesthesia and abdominal surgery upon plasma thromboxane B concentrations in horses. 2004 Vet Anaesth Analg pmid:15053753
Menzies-Gow NJ et al. Endotoxin-induced digital vasoconstriction in horses: associated changes in plasma concentrations of vasoconstrictor mediators. 2004 Equine Vet. J. pmid:15147137
Ghuysen A et al. Effect of BM-573 [N-terbutyl-N'-[2-(4'-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a dual thromboxane synthase inhibitor and thromboxane receptor antagonist, in a porcine model of acute pulmonary embolism. 2004 J. Pharmacol. Exp. Ther. pmid:15121765
Caprani A et al. Experimental evidence of a potentially increased thrombo-embolic disease risk by domestic electromagnetic field exposure. 2004 Bioelectromagnetics pmid:15114641
Di Minno G and Violi F Aspirin resistance and diabetic angiopathy: back to the future. 2004 Thromb. Res. pmid:15115664
Torsney E et al. Thrombosis and neointima formation in vein grafts are inhibited by locally applied aspirin through endothelial protection. 2004 Circ. Res. pmid:15117816
Wang YY et al. Inhibition of platelet aggregation by polyaspartoyl L-arginine and its mechanism. 2004 Acta Pharmacol. Sin. pmid:15066215
Harizi H et al. Inhibition of IL-6, TNF-alpha, and cyclooxygenase-2 protein expression by prostaglandin E2-induced IL-10 in bone marrow-derived dendritic cells. 2004 Cell. Immunol. pmid:15219461
Park HS et al. Dietary conjugated linoleic acid increases the mRNA ratio of Bax/Bcl-2 in the colonic mucosa of rats. 2004 J. Nutr. Biochem. pmid:15068816
Zhang C et al. Inhibition of inflammation contributes to organ protection of atenolol in sinoaortic-denervated rats. 2004 J. Cardiovasc. Pharmacol. pmid:15071353
Bruno A et al. Serial urinary 11-dehydrothromboxane B2, aspirin dose, and vascular events in blacks after recent cerebral infarction. 2004 Stroke pmid:14963281
Kwak SH et al. Effects of propofol on endotoxin-induced acute lung injury in rabbit. 2004 J. Korean Med. Sci. pmid:14966342
de La Puerta Vázquez R et al. Effects of different dietary oils on inflammatory mediator generation and fatty acid composition in rat neutrophils. 2004 Metab. Clin. Exp. pmid:14681843
Minuz P et al. Determinants of platelet activation in human essential hypertension. 2004 Hypertension pmid:14656953
Capone ML et al. Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects. 2004 Circulation pmid:15037526
Liu P et al. [Effects of the extracts from decoction for resuscitation and its component herbs on PGI2, TXA2 and NO release from rat vascular endothelial cells under hypoxia in vitro]. 2004 Zhongguo Zhong Yao Za Zhi pmid:15631091
Yang JP et al. [Changes of the platelet function and serum anticardiolipin antibody in patients with pulmonary thromboembolism]. 2004 Zhonghua Jie He He Hu Xi Za Zhi pmid:15634381
Wang MS et al. [The effects of lupus anticoagulant on pulmonary thromboembolism]. 2004 Zhonghua Jie He He Hu Xi Za Zhi pmid:15634384
Franz KB A functional biological marker is needed for diagnosing magnesium deficiency. 2004 J Am Coll Nutr pmid:15637224
Ganafa AA et al. Amlodipine attenuates oxidative stress-induced hypertension. 2004 Am. J. Hypertens. pmid:15363814
Cardoni RL and Antúnez MI Circulating levels of cyclooxygenase metabolites in experimental Trypanosoma cruzi infections. 2004 Mediators Inflamm. pmid:15545053
Wu JX et al. Changes in somatostatin receptor expression of the pancreas and effectiveness of octreotide in rats with acute necrotizing pancreatitis. 2004 Chin J Dig Dis pmid:15612670
Berrougui H et al. Argan (Argania spinosa) oil lowers blood pressure and improves endothelial dysfunction in spontaneously hypertensive rats. 2004 Br. J. Nutr. pmid:15613254
Fan JG et al. [Dynamic changes of plasma levels of prostacycline and thromboxane A2 and their correlation with the severity of hepatic injury in rats with nonalcoholic fatty liver disease]. 2004 Zhonghua Gan Zang Bing Za Zhi pmid:15623379
Díaz AM et al. Phenylpropanoid glycosides from Scrophularia scorodonia: in vitro anti-inflammatory activity. 2004 Life Sci. pmid:15010262
Rotondo S et al. Licofelone, an inhibitor of cyclooxygenase and 5-lipoxygenase, specifically inhibits cyclooxygenase-1-dependent platelet activation. 2004 Eur. J. Pharmacol. pmid:15044038
Guay J et al. Carrageenan-induced paw edema in rat elicits a predominant prostaglandin E2 (PGE2) response in the central nervous system associated with the induction of microsomal PGE2 synthase-1. 2004 J. Biol. Chem. pmid:15044444
Véricel E et al. Diabetic patients without vascular complications display enhanced basal platelet activation and decreased antioxidant status. 2004 Diabetes pmid:15047620
Yugar-Toledo JC et al. Uncontrolled hypertension, uncompensated type II diabetes, and smoking have different patterns of vascular dysfunction. 2004 Chest pmid:15006938
Akbiyik F et al. Human bone marrow megakaryocytes and platelets express PPARgamma, and PPARgamma agonists blunt platelet release of CD40 ligand and thromboxanes. 2004 Blood pmid:15130939
Tanigawa T et al. Anti-inflammatory effect of two isoforms of COX in H. pylori-induced gastritis in mice: possible involvement of PGE2. 2004 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12958020