Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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DeFilippis AP et al. | Fatty acids and TxA(2) generation, in the absence of platelet-COX-1 activity. | 2014 | Nutr Metab Cardiovasc Dis | pmid:24370448 |
Togna AR et al. | 4-Methylcoumarin derivatives with anti-inflammatory effects in activated microglial cells. | 2014 | Biol. Pharm. Bull. | pmid:24389482 |
Osmond DA et al. | Clopidogrel preserves whole kidney autoregulatory behavior in ANG II-induced hypertension. | 2014 | Am. J. Physiol. Renal Physiol. | pmid:24477682 |
Cathcart MC et al. | Thromboxane synthase expression and correlation with VEGF and angiogenesis in non-small cell lung cancer. | 2014 | Biochim. Biophys. Acta | pmid:24480048 |
Chou YI et al. | Correlations of platelet-derived microparticles with thromboxane B2, platelet-activating factor, endothelin-1, and neutrophil to lymphocyte ratio in patients with coronary intermediate lesions. | 2014 | Biomarkers | pmid:25391885 |
Fuentes E et al. | A novel role of Eruca sativa Mill. (rocket) extract: antiplatelet (NF-κB inhibition) and antithrombotic activities. | 2014 | Nutrients | pmid:25514563 |
Reddoch KM et al. | Hemostatic function of apheresis platelets stored at 4°C and 22°C. | 2014 | Shock | pmid:24169210 |
Hill TL et al. | The effect of tramadol and indomethacin coadministration on gastric barrier function in dogs. | 2014 May-Jun | J. Vet. Intern. Med. | pmid:24684670 |
Liu TF et al. | [Correlation between the level of the urinary 11-dehydrothromboxane B2 and the clinical efficacy of aspirin in patients with type 2 diabetes and coronary artery disease]. | 2015 | Beijing Da Xue Xue Bao | pmid:26679651 |
Holland B et al. | Pharmacokinetics and pharmacodynamics of three formulations of firocoxib in healthy horses. | 2015 | J. Vet. Pharmacol. Ther. | pmid:25378135 |