Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Jacobi KE et al. | Determination of eicosanoid and cytokine production in salvaged blood, stored red blood cell concentrates, and whole blood. | 2000 | J Clin Anesth | pmid:10818321 |
Tanus-Santos JE et al. | Endothelin ET(A) receptor antagonism attenuates the pressor effects of nicotine in rats. | 2000 | Eur. J. Pharmacol. | pmid:10822051 |
Turpeinen AM et al. | Similar responses in hemostatic factors after consumption of wholemeal rye bread and low-fiber wheat bread. | 2000 | Eur J Clin Nutr | pmid:10822290 |
Romano M et al. | Fluvastatin reduces soluble P-selectin and ICAM-1 levels in hypercholesterolemic patients: role of nitric oxide. | 2000 | J. Investig. Med. | pmid:10822898 |
Sheu JR et al. | Mechanisms involved in the antiplatelet activity of Staphylococcus aureus lipoteichoic acid in human platelets. | 2000 | Thromb. Haemost. | pmid:10823277 |
Nosál' R et al. | Chloroquine: a multipotent inhibitor of human platelets in vitro. | 2000 | Thromb. Res. | pmid:10828481 |
Maccarrone M et al. | Activation of different lipoxygenase isozymes induces apoptosis in human erythroleukemia and neuroblastoma cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10833416 |
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Numminen H et al. | The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation. | 2000 | Stroke | pmid:10835443 |
Sakamoto K et al. | An imbalance in plasma prostanoids in patients with Raynaud's phenomenon and pulmonary vasospasm. | 1999 | Eur. Respir. J. | pmid:10836338 |
Cracowski JL et al. | Human internal mammary artery contraction by isoprostaglandin f(2alpha) type-III [8-iso-prostaglandin F(2alpha)]. | 2000 | Eur. J. Pharmacol. | pmid:10844110 |
Rioja I et al. | An anti-inflammatory ditriazine inhibiting leukocyte functions and expression of inducible nitric oxide synthase and cyclo-oxygenase-2. | 2000 | Eur. J. Pharmacol. | pmid:10844115 |
Tran HS et al. | The cardiovascular hemodynamics and leukotriene kinetics during prostacyclin and anti-prostacyclin antibody infusions in septic shock. | 2000 | Shock | pmid:10847636 |
Carty E et al. | Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: anti-inflammatory profile in inflammatory bowel disease. | 2000 | Aliment. Pharmacol. Ther. | pmid:10848666 |
Theriot JA et al. | Dietary chloride does not correlate with urinary thromboxane in deoxycorticosterone acetate-treated rats. | 2000 | J. Lab. Clin. Med. | pmid:10850649 |
Mizugaki M | [Microdetermination of eicosanoids using mass spectrometry]. | 2000 | Nippon Yakurigaku Zasshi | pmid:10876809 |
Depré M et al. | Pharmacokinetics, COX-2 specificity, and tolerability of supratherapeutic doses of rofecoxib in humans. | 2000 | Eur. J. Clin. Pharmacol. | pmid:10877012 |
Moon CH et al. | Mechanism for antiplatelet effect of onion: AA release inhibition, thromboxane A(2)synthase inhibition and TXA(2)/PGH(2)receptor blockade. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883058 |
Lasserre B et al. | Modifications in the TXA(2) and PGI(2) plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the rabbit. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883059 |
Bereczki C et al. | The roles of platelet function, thromboxane, blood lipids and nitric oxide in hypertension of children and adolescents. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883060 |