| MeSH term | MeSH ID | Detail |
|---|---|---|
| Ulcer | D014456 | 16 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Hypertension, Pulmonary | D006976 | 32 associated lipids |
| Endometriosis | D004715 | 29 associated lipids |
| Uterine Neoplasms | D014594 | 18 associated lipids |
| Myocardial Infarction | D009203 | 21 associated lipids |
| Proteinuria | D011507 | 30 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Magnesium Deficiency | D008275 | 9 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Thorngren M et al. | Thromboxane A2 in skin-bleeding-time blood and in clotted venous blood before and after administration of acetylsalicylic acid. | 1983 | Lancet | pmid:6133107 |
| Drake TS et al. | Peritoneal fluid prostanoids in unexplained infertility. | 1983 | Am. J. Obstet. Gynecol. | pmid:6614085 |
| Stenson WF and Lobos E | Inhibition of platelet thromboxane synthetase by sulfasalazine. | 1983 | Biochem. Pharmacol. | pmid:6135423 |
| Chang J et al. | Effects of thiazinamium chloride, promethazine and chlorpromazine on thromboxane B2 synthesis, phagocytosis and respiratory burst by rat alveolar macrophages. | 1983 | Biochem. Pharmacol. | pmid:6138040 |
| Deckmyn H et al. | Manipulation of the local thromboxane and prostacyclin balance in vivo by the antithrombotic compounds dazoxiben, acetylsalicylic acid and nafazatrom. | 1983 | Biochem. Pharmacol. | pmid:6578796 |
| Goetzl EJ et al. | Enhancement of human neutrophil adherence by synthetic leukotriene constituents of the slow-reacting substance of anaphylaxis. | 1983 | Immunology | pmid:6193056 |
| Palmer RM and Salmon JA | Release of leukotriene B4 from human neutrophils and its relationship to degranulation induced by N-formyl-methionyl-leucyl-phenylalanine, serum-treated zymosan and the ionophore A23187. | 1983 | Immunology | pmid:6309653 |
| Winter M et al. | Synthesis of thromboxane B2 in uraemia and the effects of dialysis. | 1983 | Thromb. Res. | pmid:6868024 |
| Samuelsson B | From studies of biochemical mechanism to novel biological mediators: prostaglandin endoperoxides, thromboxanes, and leukotrienes. Nobel Lecture, 8 December 1982. | 1983 | Biosci. Rep. | pmid:6315101 |
| Lismonde M et al. | [The presence of 6-oxo-PGF1alpha and thromboxane B2 in peritoneal exudates released by iota-carrageenan in the rat]. | 1983 | Arch. Int. Physiol. Biochim. | pmid:6198994 |
| Gorman RR et al. | Inhibition of platelet thromboxane A2 synthase activity by sodium 5-(3'-pyridinylmethyl)benzofuran-2-carboxylate. | 1983 | Prostaglandins | pmid:6316421 |
| Tolman EL and Fuller BL | Inhibition of thromboxane synthesis in guinea pig lung and human platelets by clotrimazole and other imidazole antifungals. | 1983 | Biochem. Pharmacol. | pmid:6316985 |
| Salmon JA et al. | The effects of BW755C and other anti-inflammatory drugs on eicosanoid concentrations and leukocyte accumulation in experimentally-induced acute inflammation. | 1983 | J. Pharm. Pharmacol. | pmid:6141244 |
| Stimler NP and O'Flaherty JT | Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues. | 1983 | Am. J. Pathol. | pmid:6624879 |
| Stratta P et al. | Warning: platelet factor 4, beta-thromboglobulin and thromboxane in donor's plasma units. | 1983 | Thromb. Haemost. | pmid:6189235 |
| McDaniel HG et al. | Platelet function abnormalities in response to arachidonic acid in the acute phase of myocardial infarction. | 1983 | Am. J. Cardiol. | pmid:6416046 |
| de Kergommeaux BD et al. | Effects of ASA on thromboxane and prostacyclin synthesis by rabbit aorta and pulmonary artery. | 1983 | Prostaglandins Leukot Med | pmid:6410417 |
| Buchanan MR et al. | The sex-related differences in aspirin pharmacokinetics in rabbits and man and its relationship to antiplatelet effects. | 1983 | Thromb. Res. | pmid:6221436 |
| Yamamoto S et al. | Enzyme immunoassay of thromboxane B2 and 6-keto-prostaglandin F1 alpha as a substitute for radioimmunoassay. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221523 |
| Weerasekera DA et al. | Chemiluminescence immunoassay of thromboxane B2. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221524 |
| Davi' G et al. | Platelet activation after adrenergic stimulation in hypertensive patients: effects of acebutolol. | 1983 | Eur. Heart J. | pmid:6352266 |
| Ito T et al. | Effects of a selective inhibitor of thromboxane synthetase (OKY-1581) in humans. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221531 |
| FitzGerald GA et al. | Aspirin inhibits endogenous prostacyclin and thromboxane biosynthesis in man. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221534 |
| FitzGerald GA et al. | Endogenous prostacyclin biosynthesis and platelet function during selective inhibition of thromboxane synthase in man. | 1983 | J. Clin. Invest. | pmid:6355181 |
| van der Giessen WJ et al. | Acute effect of cigarette smoking on cardiac prostaglandin synthesis and platelet behavior in patients with coronary heart disease. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221546 |
| Jouve R et al. | [Plasma thromboxane B2 and capacity of the aorta to produce prostacyclin in arteriopathies of the lower extremities]. | 1983 | J Mal Vasc | pmid:6355348 |
| Bach MK et al. | In vivo and in vitro actions of a new selective inhibitor of leukotriene C and D synthesis. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221551 |
| Mehta J et al. | Stimulation of vessel wall prostacyclin by selective thromboxane synthetase inhibitor OKY 1581. | 1983 | Prostaglandins Leukot Med | pmid:6356153 |
| Grose JH et al. | Imbalanced prostacyclin and thromboxane A2 production in essential hypertension. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221555 |
| Henriksen RA and Brotherton AF | Evidence that activation of platelets and endothelium by thrombin involves distinct sites of interaction. Studies with the dysthrombin, Thrombin Quick I. | 1983 | J. Biol. Chem. | pmid:6358210 |
| Kaliman J et al. | [Venous prostacycline synthesis and plasma thromboxane B2 after low-dose aspirin]. | 1983 | Wien. Klin. Wochenschr. | pmid:6359724 |
| Ylikorkala O et al. | Prostacyclin and thromboxane in ovarian cancer: effect of cytostatics and prostaglandin synthesis inhibitors. | 1983 | Gynecol. Oncol. | pmid:6360817 |
| Tada M et al. | [Biochemistry of coronary artery disease--prostaglandins]. | 1983 | Rinsho Byori | pmid:6361336 |
| Hardisty RM et al. | A new congenital defect of platelet secretion: impaired responsiveness of the platelets to cytoplasmic free calcium. | 1983 | Br. J. Haematol. | pmid:6830700 |
| Jørgensen KA et al. | The survival of pig to rabbit renal xenografts during inhibition of thromboxane synthesis. | 1983 | Thromb. Res. | pmid:6364449 |
| Feddersen CO et al. | Leukotriene E4 causes pulmonary vasoconstriction, not inhibited by meclofenamate. | 1983 | Prostaglandins | pmid:6098932 |
| Randall MJ and Wilding RI | Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with dazoxiben hydrochloride (UK 37,248-01). | 1983 | Br J Clin Pharmacol | pmid:6687429 |
| Bruckner G et al. | Dietary trilinoelaidate: effects on hematological parameters, serum eicosanoids and tissue fatty acid composition in rats. | 1983 | J. Nutr. | pmid:6687476 |
| Bessin P et al. | Acute circulatory collapse caused by platelet-activating factor (PAF-acether) in dogs. | 1983 | Eur. J. Pharmacol. | pmid:6687572 |
| Ingerman-Wojenski CM et al. | Early morphological changes in the endothelium of a peripheral artery of rabbits fed an atherogenic diet. | 1983 | Exp. Mol. Pathol. | pmid:6687574 |
| Morita I et al. | Stimulation of eicosapentaenoic acid metabolism in washed human platelets by 12-hydroperoxyeicosatetraenoic acid. | 1983 | J. Biol. Chem. | pmid:6309794 |
| Hartung HP and Toyka KV | Tuftsin stimulates the release of oxygen radicals and thromboxane from macrophages. | 1983 | Immunol. Lett. | pmid:6687720 |
| D'Angelo A et al. | Effect of des-amino-D-arginine vasopressin (DDAVP) on plasma levels of platelet and endothelial cell release products. | 1983 | Thromb. Haemost. | pmid:6687766 |
| Ku EC et al. | Characterization of imidazo[1,5-a]pyridine-5-hexanoic acid (CGS 13080) as a selective thromboxane synthetase inhibitor using in vitro and in vivo biochemical models. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6687803 |
| Anderegg K et al. | Effects of a pyridine derivative thromboxane synthetase inhibitor and its inactive isomer in endotoxic shock in the rat. | 1983 | Br. J. Pharmacol. | pmid:6687819 |
| Todd MH et al. | The involvement of prostaglandins and thromboxanes in the response to pulmonary embolism in anaesthetized rabbits and isolated perfused lungs. | 1983 | Thromb. Res. | pmid:6687961 |
| Di Minno G et al. | Monitoring the entry of new platelets into the circulation after ingestion of aspirin. | 1983 | Blood | pmid:6404326 |
| Higgs GA et al. | The source of thromboxane and prostaglandins in experimental inflammation. | 1983 | Br. J. Pharmacol. | pmid:6652359 |
| Anton RF et al. | In vivo regional levels of PGE and thromboxane in mouse brain: effect of decapitation, focused microwave fixation, and indomethacin. | 1983 | Prostaglandins | pmid:6658001 |
| Mahoney D et al. | Influence of dietary polyunsaturated fatty acids on renal & aortic prostaglandin synthesis in 1 kidney 1 clip Goldblatt hypertensive rats. | 1983 | Prostaglandins | pmid:6658002 |
| Martin JF et al. | The biological significance of platelet volume: its relationship to bleeding time, platelet thromboxane B2 production and megakaryocyte nuclear DNA concentration. | 1983 | Thromb. Res. | pmid:6658722 |
| Cohen RA et al. | 5-Hydroxytryptamine can mediate endothelium-dependent relaxation of coronary arteries. | 1983 | Am. J. Physiol. | pmid:6660308 |
| Cortellaro M et al. | Transcoronary platelet thromboxane A2 formation without platelet trapping in patients with coronary stenosis-effect of sulphinpyrazone treatment. | 1983 | Thromb. Haemost. | pmid:6665767 |
| De Caterina R et al. | Antiplatelet effects of isosorbide dinitrate in man. | 1983 | Z Kardiol | pmid:6666233 |
| Smith EF et al. | RCS from human platelets: is it only thromboxane? | 1983 | Eur. J. Pharmacol. | pmid:6667711 |
| Sakanishi N et al. | [Effect of reduced glutathione on endotoxin shock]. | 1983 | Masui | pmid:6668649 |
| Chong KP et al. | Vasopressin stimulates thromboxane synthesis in isolated hamster hepatocytes: relation to hepatocyte calcium content. | 1983 | Prostaglandins | pmid:6419286 |
| Karmali RA et al. | Prostaglandins in breast cancer: relationship to disease stage and hormone status. | 1983 | Br. J. Cancer | pmid:6416285 |
| Sautebin L et al. | Preferential utilization of endogenous arachidonate by cyclo-oxygenase in incubations of human platelets. | 1983 | FEBS Lett. | pmid:6407867 |
| Fukumoto S and Tanaka K | Protective effects of thromboxane A2 synthetase inhibitors on endotoxin shock. | 1983 | Prostaglandins Leukot Med | pmid:6576388 |
| Kinney EL et al. | Mechanism of action of amrinone: role of thromboxane synthetase inhibition. | 1983 | Prostaglandins Leukot Med | pmid:6576389 |
| Hawkey CJ et al. | Imbalance of prostacyclin and thromboxane synthesis in Crohn's disease. | 1983 | Gut | pmid:6578172 |
| Zijlstra FJ et al. | Separation of the two components of the contractile activity of leukotriene C4 on the guinea pig lung parenchymal strip. | 1983 | Prostaglandins Leukot Med | pmid:6578519 |
| Mahoney DP et al. | Radioimmunoassay of prostaglandins and thromboxane B2 in extracted and unextracted urine and serum using an iodinated ligand. | 1983 | Prostaglandins Leukot Med | pmid:6579570 |
| Güllner HG et al. | Renal thromboxane excretion in Brattleboro rats with hereditary hypothalamic diabetes insipidus. Effect of vasopressin treatment. | 1983 | Prostaglandins Leukot Med | pmid:6580653 |
| Sakanishi N et al. | Thromboxane A2 and hemodynamic-biochemical parameters in canine endotoxin shock. | 1983 | Bull. Tokyo Med. Dent. Univ. | pmid:6580966 |
| Orlandi M et al. | Normal plasma thromboxane B2 (TXB2) and 6-keto-PGF1 alpha levels in childhood diabetes. | 1983 | Prostaglandins Leukot Med | pmid:6583712 |
| Männistö J and Uotila P | Cigarette smoke ventilation decreases thromboxane B2 metabolism in isolated rat lungs. | 1983 | Prostaglandins Leukot Med | pmid:6583713 |
| Rao GH et al. | Ibuprofen protects platelet cyclooxygenase from irreversible inhibition by aspirin. | 1983 Jul-Aug | Arteriosclerosis | pmid:6411052 |
| Konieczkowski M et al. | Glomerular synthesis of prostaglandins and thromboxane in spontaneously hypertensive rats. | 1983 Jul-Aug | Hypertension | pmid:6407990 |
| Stuart MJ | The effect of irradiation on platelet arachidonic acid metabolism. | 1983 Mar-Apr | Transfusion | pmid:6404019 |
| Newman WH et al. | Increased myocardial release of prostacyclin in dogs with heart failure. | 1983 Mar-Apr | J. Cardiovasc. Pharmacol. | pmid:6188889 |
| Coker SJ and Parratt JR | Nifedipine reduces arrhythmias but does not alter prostanoid release during coronary artery occlusion and reperfusion in anaesthetised greyhounds. | 1983 May-Jun | J. Cardiovasc. Pharmacol. | pmid:6191139 |
| Peskar BM | Effects of carbenoxolone on the gastric mucosal prostaglandin and thromboxane system. | 1983 Sep-Oct | Acta Gastroenterol. Belg. | pmid:6324520 |
| Burke SE et al. | Protection of ischemic cat myocardium by CGS-13080, a selective potent thromboxane A2 synthesis inhibitor. | 1983 Sep-Oct | J. Cardiovasc. Pharmacol. | pmid:6195474 |
| Ito T et al. | Selective thromboxane synthetase inhibitor and ischemic heart disease. | 1984 | Biomed. Biochim. Acta | pmid:6542777 |
| De Clerck F et al. | Platelet-vessel wall interactions in hemostasis: implication of 5-hydroxytryptamine. | 1984 | Agents Actions | pmid:6543415 |
| Menys VC and Davies JA | Thromboxane-mediated activation of platelets and enhancement of platelet uptake onto collagen-coated glass or deendothelialized rabbit aorta. Comparative effects of a thromboxane antagonist (EPO45) and a thromboxane synthetase inhibitor (dazoxiben). | 1984 | Lab. Invest. | pmid:6546403 |
| Le Breton GC et al. | 2-(6-carboxyhexyl)cyclopentanone hexylhydrazone: a potent inhibitor of the blood platelet cyclo-oxygenase. | 1984 | Prostaglandins | pmid:6427851 |
| Schwartz D et al. | Renal arachidonic acid metabolism and cellular changes in the rabbit renal vein constricted kidney: inflammation as a common process in renal injury models. | 1984 | Prostaglandins | pmid:6427853 |
| Stahl RA et al. | Glomerular prostaglandin formation in two-kidney, one-clip hypertensive rats. | 1984 | Am. J. Physiol. | pmid:6507633 |
| Kääpä P et al. | Thromboxane B2 production by fetal and neonatal platelets: effect of idiopathic respiratory distress syndrome and birth asphyxia. | 1984 | Pediatr. Res. | pmid:6472947 |
| Gachályi B et al. | In vitro effect of cimetidine on ADP induced platelet aggregation and thromboxane A2 synthesis in man. | 1984 | Thromb. Res. | pmid:6474407 |
| Fitzpatrick F et al. | Development of a gas chromatographic-mass spectrometric method using a stable isotope internal standard for quantitation of thromboxane B2. | 1984 | Thromb. Res. | pmid:6474413 |
| D'Angelo A et al. | Increased production of platelet thromboxane B2 in non-insulin-dependent diabetes. Relationship to vascular complications. | 1984 | Eur. J. Clin. Invest. | pmid:6428908 |
| Uotila P et al. | Prostanoids and hemodynamics in man before and during cardiopulmonary bypass. | 1984 | Prostaglandins | pmid:6335260 |
| Kawai C | New horizons in cardiology. | 1984 | Int. J. Cardiol. | pmid:6334040 |
| Hänsch GM et al. | Macrophages release arachidonic acid, prostaglandin E2, and thromboxane in response to late complement components. | 1984 | J. Immunol. | pmid:6432907 |
| Rachmilewitz D and Karmeli F | Effect of nufenoxole on human colonic prostanoid synthesis, Na-K-ATPase and adenylate cyclase activities. | 1984 | Eur. J. Pharmacol. | pmid:6152213 |
| Yui Y et al. | Intravenous infusion of a selective inhibitor of thromboxane A2 synthetase in man: influence on thromboxane B2 and 6-keto-prostaglandin F1 alpha levels and platelet aggregation. | 1984 | Circulation | pmid:6434196 |
| Lee EC et al. | Functional responses of tumor cells to phorbol esters: role for prostaglandins. | 1984 | Oncology | pmid:6587276 |
| Coker SJ and Parratt JR | The effects of nafazatrom on arrhythmias and prostanoid release during coronary artery occlusion and reperfusion in anaesthetized greyhounds. | 1984 | J. Mol. Cell. Cardiol. | pmid:6366241 |
| Alster P and Wennmalm A | Effect of nicotine on the formation of prostacyclin-like activity and thromboxane in rabbit aorta and platelets. | 1984 | Br. J. Pharmacol. | pmid:6367870 |
| Dembinska-Kieć A et al. | Formation of leukotriene C4-like material by rat brain tissue. | 1984 | Eur. J. Pharmacol. | pmid:6426980 |
| Schultze G et al. | Effect of cyclosporine on the generation of prostanoids by cultured peripheral lymphocytes. | 1984 | Transplant. Proc. | pmid:6592863 |
| Zipser RD et al. | Therapeutic trial of thromboxane synthesis inhibition in the hepatorenal syndrome. | 1984 | Gastroenterology | pmid:6593268 |
| Vapaatalo H et al. | Prostanoids in blood pressure regulation and their role in the blood pressure lowering effects induced by changes in dietary fats. | 1984 | Ann. Clin. Res. | pmid:6398981 |
| Dahl ML and Uotila P | Salicylate does not interfere with aspirin in human blood in vivo. | 1984 | Prostaglandins Leukot Med | pmid:6585840 |
| Dahl ML and Uotila P | Thromboxane formation during blood clotting is decreased by verapamil. | 1984 | Prostaglandins Leukot Med | pmid:6585842 |
| Oglesby TD and Gorman RR | The inhibition of arachidonic acid metabolism in human platelets by RHC 80267, a diacylglycerol lipase inhibitor. | 1984 | Biochim. Biophys. Acta | pmid:6424715 |