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Synergistic effect of D-003 and aspirin on experimental thrombosis models. |
2003 |
Prostaglandins Leukot. Essent. Fatty Acids |
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Prostacyclin/thromboxane early changes in pregnancies that are complicated by preeclampsia. |
2003 |
Am. J. Obstet. Gynecol. |
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Pharmacological evaluation of the novel thromboxane modulator BM-567 (I/II). Effects of BM-567 on platelet function. |
2003 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12538090
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Tanaka S et al. |
High dose of inhaled fluticasone reduces high levels of urinary leukotriene E4 in the early morning in mild and moderate nocturnal asthma. |
2003 |
Chest |
pmid:14605047
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Inhibition of prostaglandin D2 clearance in rat hepatocytes by the thromboxane receptor antagonists daltroban and ifetroban and the thromboxane synthase inhibitor furegrelate. |
2003 |
Biochem. Pharmacol. |
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De La Cruz P et al. |
Effects of clopidogrel and ticlopidine on experimental diabetic ischemic retinopathy in rats. |
2003 |
Naunyn Schmiedebergs Arch. Pharmacol. |
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The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. |
2003 |
Proc. Natl. Acad. Sci. U.S.A. |
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Bosetti F et al. |
Valproic acid down-regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase-1 and -2 in rat brain. |
2003 |
J. Neurochem. |
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Effects of exercise on platelet and aortic functions in aged rats. |
2003 |
Acta Physiol. Scand. |
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Tissue chamber model of acute inflammation in farm animal species. |
2003 |
Res. Vet. Sci. |
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Daily prickly pear consumption improves platelet function. |
2003 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12878452
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[Protective effect of selective cyclooxygenase-2 inhibitor on alcohol-induced liver injury in rats]. |
2003 |
Zhonghua Gan Zang Bing Za Zhi |
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Effects of phenacetin and its metabolite p-phenetidine on COX-1 and COX-2 activities and expression in vitro. |
2003 |
Thromb. Res. |
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Inflammation is involved in the organ damage induced by sinoaortic denervation in rats. |
2003 |
J. Hypertens. |
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Platelet aggregation, thromboxane production and thrombogenic ratio in postmenopausal women consuming high oleic acid-sunflower oil or palmolein. |
2003 |
Eur J Nutr |
pmid:14673602
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Al-Waili NS and Boni NS |
Natural honey lowers plasma prostaglandin concentrations in normal individuals. |
2003 |
J Med Food |
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Gu L et al. |
[Advances in the study on molecular mechanism of diabetic nephropathy treated with Rheum officinale]. |
2003 |
Zhongguo Zhong Yao Za Zhi |
pmid:15224660
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Inhibition of prostaglandin synthesis during polystyrene microsphere-induced pulmonary embolism in the rat. |
2003 |
Am. J. Physiol. Lung Cell Mol. Physiol. |
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Lipid and protein oxidation contribute to a prothrombotic state in patients with type 2 diabetes mellitus. |
2003 |
J. Thromb. Haemost. |
pmid:12871497
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Davì G et al. |
Enhanced lipid peroxidation and platelet activation in the early phase of type 1 diabetes mellitus: role of interleukin-6 and disease duration. |
2003 |
Circulation |
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Montuschi P et al. |
Exhaled leukotrienes and prostaglandins in COPD. |
2003 |
Thorax |
pmid:12832671
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Wolfram RM et al. |
Narghile (water pipe) smoking influences platelet function and (iso-)eicosanoids. |
2003 |
Life Sci. |
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Beck-Speier I et al. |
Sulfur-related air pollutants induce the generation of platelet-activating factor, 5-lipoxygenase- and cyclooxygenase-products in canine alveolar macrophages via activation of phospholipases A2. |
2003 |
Prostaglandins Other Lipid Mediat. |
pmid:14518563
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Tsipas G and Morphake P |
Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity. |
2003 |
J. Nutr. Biochem. |
pmid:14629893
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Davì G et al. |
Platelet activation in obese women: role of inflammation and oxidant stress. |
2002 Oct 23-30 |
JAMA |
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Hayashi M et al. |
Characterization of five marker levels of the hemostatic system and endothelial status in normotensive pregnancy and pre-eclampsia. |
2002 Nov-Dec |
Eur. J. Haematol. |
pmid:12460234
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Effect of black tea on (iso-)prostaglandins and platelet aggregation in healthy volunteers. |
2002 May-Jun |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12144875
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Differential actions of naftopidil, doxazosin and nifedipine on platelet thromboxane generation and platelet-derived growth factor efflux in vitro. |
2002 Aug-Sep |
Platelets |
pmid:12189011
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Effect of submaximal and incremental upper extremity exercise on platelet function and the role of blood shear stress. |
2002 |
Thromb. Res. |
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Cyclooxygenase isozyme expression and intimal hyperplasia in a rat model of balloon angioplasty. |
2002 |
J. Pharmacol. Exp. Ther. |
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Effect of the selective COX-2 inhibitors, celecoxib and rofecoxib in rat acute models of inflammation. |
2002 |
Inflamm. Res. |
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Signs of platelet activation, but not lipid peroxidation, in fetal blood associated with functional and structural umbilicoplacental lesions in pregnancies complicated by impaired glucose metabolism. |
2002 |
J. Matern. Fetal. Neonatal. Med. |
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Sesquiterpenes from Jasonia glutinosa: in vitro anti-inflammatory activity. |
2002 |
Biol. Pharm. Bull. |
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The effect of submaximal exercise on platelet aggregation during late follicular and midluteal phases in women. |
2002 |
Thromb. Res. |
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Effects of antihistamines on leukotriene and cytokine release from dispersed nasal polyp cells. |
2002 |
Arzneimittelforschung |
pmid:11878205
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Role of recombinant hirudin in a pig-to-human lung transplantation model. |
2002 |
Transplant. Proc. |
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Effect of berberine on arachidonic acid metabolism in rabbit platelets and endothelial cells. |
2002 |
Thromb. Res. |
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Pharmacodynamics and enantioselective pharmacokinetics of racemic carprofen in the horse. |
2002 |
J. Vet. Pharmacol. Ther. |
pmid:12485349
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Pulmonary prostacyclin is associated with less severe respiratory distress in preterm infants. |
2002 |
Early Hum. Dev. |
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Enhanced vascular effects of the Ca(2+) channel agonist Bay K 8644 in pregnant rabbits. |
2002 |
Am. J. Physiol. Regul. Integr. Comp. Physiol. |
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[Relationship between cyclooxygenase-2 protein expression, prostaglandins levels and biologic behavior in ovarian carcinoma tissue]. |
2002 |
Zhonghua Fu Chan Ke Za Zhi |
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NCX4016 (NO-aspirin) reduces infarct size and suppresses arrhythmias following myocardial ischaemia/reperfusion in pigs. |
2002 |
Br. J. Pharmacol. |
pmid:11959790
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[Changes of blood vessel active substances in acute pulmonary embolism induced by echinococus granulous cyst in rabbits]. |
2002 |
Zhonghua Jie He He Hu Xi Za Zhi |
pmid:12490126
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Mechanisms involved in the antiplatelet activity of midazolam in human platelets. |
2002 |
Anesthesiology |
pmid:11873041
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Study on the usefulness of seratrodast in the treatment of chronic pulmonary emphysema. |
2002 |
Arzneimittelforschung |
pmid:12442639
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Induction of thromboxane A2 synthesizing enzymes in DMSO-induced granulocytic differentiation of HL-60 cells. |
2002 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12468261
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The use of ginger (Zingiber officinale Rosc.) as a potential anti-inflammatory and antithrombotic agent. |
2002 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12468270
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Mechanisms involved in the antiplatelet activity of magnesium in human platelets. |
2002 |
Br. J. Haematol. |
pmid:12472585
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Nitric oxide, anti-inflammatory drugs on renal prostaglandins and cyclooxygenase-2. |
2002 |
Hypertension |
pmid:11897764
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Increased oxidative stress and platelet activation in patients with hypertension and renovascular disease. |
2002 |
Circulation |
pmid:12451006
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Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo. |
2002 |
Cancer Res. |
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Differential regulation of prostacyclin and thromboxane by dexamethasone and celecoxib during oxidative stress in newborn rabbits. |
2002 |
Prostaglandins Other Lipid Mediat. |
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Inhibition of platelet aggregation and expression of alpha granule membrane protein 140 and thromboxane B2 with pravastatin therapy for hypercholesterolemia. |
2002 |
J Assoc Acad Minor Phys |
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Differential effect of FR122047, a selective cyclo-oxygenase-1 inhibitor, in rat chronic models of arthritis. |
2002 |
Br. J. Pharmacol. |
pmid:11834626
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Effects of the selective inhibition of platelet thromboxane synthesis on the platelet-subendothelium interaction. |
2002 |
Br. J. Pharmacol. |
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Aspirin and urinary 11-dehydrothromboxane B(2) in African American stroke patients. |
2002 |
Stroke |
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Modulation of platelet aggregation by areca nut and betel leaf ingredients: roles of reactive oxygen species and cyclooxygenase. |
2002 |
Free Radic. Biol. Med. |
pmid:11978487
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Cyclooxygenase selectivity of nonsteroidal anti-inflammatory drugs in canine blood. |
2002 |
Am. J. Vet. Res. |
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[The changes of thromboxane B2 (TXB2) and 6-keto-prostaglandin F1 alpha(6-keto-PGF1 alpha) in the lungs of rats drowned in hypothermic-sea-water]. |
2002 |
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi |
pmid:14694611
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Opposite effects of nicotinic acid and pyridoxine on systemic prostacyclin, thromboxane and leukotriene production in man. |
2002 |
Pharmacol. Toxicol. |
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Effect of the ingestion of Ginkgo biloba extract on platelet aggregation and urinary prostanoid excretion in healthy and Type 2 diabetic subjects. |
2002 |
Thromb. Res. |
pmid:12590952
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Comments on "Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications". |
2002 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12445490
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Effects of pranlukast on chemical mediators in induced sputum on provocation tests in atopic and aspirin-intolerant asthmatic patients. |
2002 |
Chest |
pmid:11796443
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Peripheral prostanoid levels and nonsteroidal anti-inflammatory drug analgesia: replicate clinical trials in a tissue injury model. |
2002 |
Clin. Pharmacol. Ther. |
pmid:12189364
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Effects of enteric-coated, low-dose aspirin on parameters of platelet function. |
2002 |
Aliment. Pharmacol. Ther. |
pmid:12197849
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Structure-function relationship and role of tumor necrosis factor-alpha-converting enzyme in the down-regulation of L-selectin by non-steroidal anti-inflammatory drugs. |
2002 |
J. Biol. Chem. |
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In vivo selectivity of a selective cyclooxygenase 2 inhibitor in the oral surgery model. |
2002 |
Clin. Pharmacol. Ther. |
pmid:12152003
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Phospholipase A2 activity in platelets of patients with uremia. |
2002 |
Platelets |
pmid:12487789
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The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis. |
2002 |
Int J Gastrointest Cancer |
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Enantiospecific effects of cytochrome P450 2C9 amino acid variants on ibuprofen pharmacokinetics and on the inhibition of cyclooxygenases 1 and 2. |
2002 |
Clin. Pharmacol. Ther. |
pmid:12152005
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Enhancement of human platelet activation by the combination of low concentrations of collagen and rabbit anticardiolipin antibodies. |
2002 |
Br. J. Haematol. |
pmid:12199800
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Investigations of new lead structures for the design of novel cyclooxygenase-2 inhibitors. |
2002 |
Eur J Med Chem |
pmid:12204472
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Association between enhanced soluble CD40L and prothrombotic state in hypercholesterolemia: effects of statin therapy. |
2002 |
Circulation |
pmid:12135935
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Association between ibuprofen, aspirin therapy found. |
2002 |
J Am Dent Assoc |
pmid:12136787
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Effects of meloxicam on platelet function in healthy adults: a randomized, double-blind, placebo-controlled trial. |
2002 |
J Clin Pharmacol |
pmid:12162470
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Discrete role for cytosolic phospholipase A(2)alpha in platelets: studies using single and double mutant mice of cytosolic and group IIA secretory phospholipase A(2). |
2002 |
J. Exp. Med. |
pmid:12163563
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Inhibition of cyclooxygenase-2 by natriuretic peptides. |
2002 |
Endocrinology |
pmid:11861506
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Huang K et al. |
Role of selenium in cytoprotection against cholesterol oxide-induced vascular damage in rats. |
2002 |
Atherosclerosis |
pmid:11947907
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Jankov RP et al. |
Thromboxane A(2) receptors mediate pulmonary hypertension in 60% oxygen-exposed newborn rats by a cyclooxygenase-independent mechanism. |
2002 |
Am. J. Respir. Crit. Care Med. |
pmid:12119234
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Effect of homocysteine on arachidonic acid release in human platelets. |
2002 |
Eur. J. Clin. Invest. |
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Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events. |
2002 |
Circulation |
pmid:11940542
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Platelet function is inhibited by non-selective non-steroidal anti-inflammatory drugs but not by cyclo-oxygenase-2-selective inhibitors in patients with rheumatoid arthritis. |
2002 |
Rheumatology (Oxford) |
pmid:11961179
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Hayashi M et al. |
The levels of five markers of hemostasis and endothelial status at different stages of normotensive pregnancy. |
2002 |
Acta Obstet Gynecol Scand |
pmid:11966476
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Valdecoxib does not impair platelet function. |
2002 |
Am J Emerg Med |
pmid:12098171
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Tsukamoto H et al. |
Simultaneous quantification of prostaglandins, isoprostane and thromboxane in cell-cultured medium using gas chromatography-mass spectrometry. |
2002 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
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Sakai H et al. |
E3040 sulphate, a novel thromboxane synthase inhibitor, blocks the Cl- secretion induced by platelet-activating factor in isolated rat colon. |
2002 |
Br. J. Pharmacol. |
pmid:12023941
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Jung K et al. |
The effect of dietary intervention through the modification of fatty acids composition and antioxidant vitamin intake on plasma TXB(2) level in Korean postmenopausal women with hypercholesterolemia. |
2002 |
J. Korean Med. Sci. |
pmid:12068132
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Jung YS et al. |
Antithrombotic effect of onion in streptozotocin-induced diabetic rat. |
2002 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12054917
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van Kraaij DJ et al. |
A comparison of the effects of nabumetone vs meloxicam on serum thromboxane B2 and platelet function in healthy volunteers. |
2002 |
Br J Clin Pharmacol |
pmid:12047490
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Appleyard CB et al. |
Temporal changes in colonic vascular architecture and inflammatory mediator levels in animal models of colitis. |
2002 |
Dig. Dis. Sci. |
pmid:12353846
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Saldeen P et al. |
Structural, functional and circulatory placental changes associated with impaired glucose metabolism. |
2002 |
Eur. J. Obstet. Gynecol. Reprod. Biol. |
pmid:12381475
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Zhang H et al. |
[Perioperative lung injury in ventricular septal defect with severe pulmonary hypertension, a clinical study of 31 cases]. |
2002 |
Zhonghua Yi Xue Za Zhi |
pmid:12425808
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Jones CJ et al. |
In vivo effects of meloxicam and aspirin on blood, gastric mucosal, and synovial fluid prostanoid synthesis in dogs. |
2002 |
Am. J. Vet. Res. |
pmid:12428662
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Buluç M et al. |
Effect of misoprostol and indomethacin on cyclooxygenase induction and eicosanoid production in carrageenan-induced air pouch inflammation in rats. |
2002 |
Prostaglandins Other Lipid Mediat. |
pmid:12428691
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Gray PA et al. |
Effects of non-steroidal anti-inflammatory drugs on cyclo-oxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors. |
2002 |
Br. J. Pharmacol. |
pmid:12429575
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Valeri CR et al. |
Circulation and hemostatic function of autologous fresh, liquid-preserved, and cryopreserved baboon platelets transfused to correct an aspirin-induced thrombocytopathy. |
2002 |
Transfusion |
pmid:12430680
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Wilner KD et al. |
Celecoxib does not affect the antiplatelet activity of aspirin in healthy volunteers. |
2002 |
J Clin Pharmacol |
pmid:12211219
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Molina V et al. |
D-003, a potential antithrombotic compound isolated from sugar cane wax with effects on arachidonic acid metabolites. |
2002 |
Prostaglandins Leukot. Essent. Fatty Acids |
pmid:12213431
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Vaughan JE and Walsh SW |
Oxidative stress reproduces placental abnormalities of preeclampsia. |
2002 |
Hypertens Pregnancy |
pmid:12517328
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Ferlito M et al. |
Implication of Galpha i proteins and Src tyrosine kinases in endotoxin-induced signal transduction events and mediator production. |
2002 |
J. Endotoxin Res. |
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