Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
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Seitz M et al. | The influence of synovial fluid from patients with rheumatoid arthritis on the proliferation of peripheral blood lymphocytes and the prostanoid release from monocytes. | 1981 | Agents Actions | pmid:7340450 |
Prancan A et al. | Platelet thromboxane production during endotoxin shock. | 1981 | Agents Actions | pmid:7340458 |
Hwang DH | Characteristics of the aggregation of platelets and the formation of prostaglandins (PGs) in rat. | 1981 | Prog. Lipid Res. | pmid:7342108 |
She HS et al. | Metabolism of prostaglandin endoperoxide by microsomes from cat lung. | 1981 | Prostaglandins | pmid:6894797 |
Shaw JO | Effects of extracellular Ca2+ and the intracellular Ca2+ antagonist 8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate on rabbit platelet conversion of arachidonic acid into thromboxane. | 1981 | Prostaglandins | pmid:6789402 |
Ingerman-Wojenski C et al. | Prostacyclin production in rabbit arteries in situ: inhibition by arachidonic acid-induced endothelial cell damage or by low-dose aspirin. | 1981 | Prostaglandins | pmid:6789404 |
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Tanabe M et al. | Coronary circulatory failure and thromboxane A2 release during coronary occlusion and reperfusion in anaesthetised dogs. | 1982 | Cardiovasc. Res. | pmid:7074670 |
Tooke JE et al. | Aspirin, prostacyclin and post-occlusive reactive hyperaemia in man. | 1982 | Prostaglandins Leukot Med | pmid:6757966 |
Herman CA et al. | Prostaglandins of the one, two, and three series affect blood pressure in the american bullfrog, Rana catesbeiana. | 1982 | Gen. Comp. Endocrinol. | pmid:6761235 |
Davì G et al. | Thromboxane B2 formation and platelet sensitivity to prostacyclin in insulin-dependent and insulin-independent diabetics. | 1982 | Thromb. Res. | pmid:6761893 |
Hornych A et al. | Radioimmunoassay measurement of thromboxane B2 in human plasma and urine. | 1982 | Prostaglandins Leukot Med | pmid:6954551 |
Mest HJ et al. | Influence of mental stress on plasma level of prostaglandins, thromboxane B2 and on circulating platelet aggregates in man. | 1982 | Prostaglandins Leukot Med | pmid:6955811 |
Graham RM et al. | Effects of short-term beta blockade on blood pressure, plasma thromboxane B2, and plasma and urinary prostaglandins E2 and F2 alpha in normal subjects. | 1982 | Clin. Pharmacol. Ther. | pmid:6120775 |
Reines HD et al. | Plasma thromboxane concentrations are raised in patients dying with septic shock. | 1982 | Lancet | pmid:6123885 |
Preston FE et al. | Low-dose aspirin inhibits platelet and venous cyclo-oxygenase in man. | 1982 | Thromb. Res. | pmid:6815823 |
Burch RM and Halushka PV | Vasopressin stimulates prostaglandin and thromboxane synthesis in toad bladder epithelial cells. | 1982 | Am. J. Physiol. | pmid:6816073 |
Neri Serheri GG et al. | Platelet aggregation and thromboxane A2 production after adrenergic stimulation in young healthy humans. | 1982 | Haemostasis | pmid:6279476 |
Dore-Duffy P | Differential effect of prostaglandins and other products of arachidonic acid metabolism on measles virus replication in Vero cells. | 1982 | Prostaglandins Leukot Med | pmid:6281810 |