Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Intermittent Claudication D007383 6 associated lipids
Jejunal Diseases D007579 3 associated lipids
Keratitis D007634 7 associated lipids
Kidney Diseases D007674 29 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Leiomyosarcoma D007890 4 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Leukopenia D007970 9 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lupus Nephritis D008181 8 associated lipids
Macular Edema D008269 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Lumley P et al. Maximal blockade of TxA2 without compromised PGI2 formation; a superior profile of the TxA2 receptor blocking drug GR32191 over aspirin. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825385
Patrono C et al. Thromboxane-dependent platelet activation as a transducer of enhanced risk of coronary and cerebral thrombosis. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825389
Zhao Y et al. Thromboxane and leukotriene generation by mononuclearcytes from cardiac transplant patients. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825392
Mistry M and Nasjletti A Role of TXA2 in the pathogenesis of severe angiotensin II-salt hypertension. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526469
Koshihara Y and Fukuda M Appearance of metabolic activities for arachidonate during development of mouse embryos. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526512
Fuse I and Tai HH Regulation of arachidonate release by G-proteins and protein kinase C in human platelets. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526540
Houtz P and Tai HH Enzyme immunoassay of thromboxane B2 using immobilized hapten and enzyme amplification. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526560
Hayashi Y et al. Radioimmunoassay of 11-dehydro-thromboxane B2 using monoclonal antibody. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526561
Knospe J et al. Derivatization of prostaglandins to corresponding anilides and analysis by HPLC. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526562
FitzGerald GA et al. Thromboxane biosynthesis and antagonism in humans. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2959047
Nowak J and FitzGerald GA In vivo formation of prostacyclin and thromboxane A2 at the site of platelet-vascular interaction in humans. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2959050
De Caterina R et al. Characteristics of thromboxane production by the isolated-perfused rat heart. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2959082
Samhoun MN et al. Differential effect of vasoactive intestinal peptide on contractions induced by leukotriene D4, histamine, and acetylcholine in guinea pig lung parenchyma in vitro. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960144
Granström E and Kumlin M Assay of thromboxane production in biological systems: reliability of TXB2 versus 11-dehydro-TXB2 as targets for measurement. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960161
Lecompte T et al. Radioimmunoassay for 11-dehydro-thromboxane B2 using an iodinated ligand: preliminary applications to human fluids. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960162
Miyazaki H et al. Microdetermination of prostaglandins and thromboxane B2 by gas chromatography/high-resolution selected-ion monitoring. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2936139
Basso N et al. Gastric mucosal prostaglandin generation in rats with stress ulcer. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221618
Foegh M et al. Prostacyclin and thromboxane release from human peritoneal macrophages. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221630
Westwick J et al. Inhibition of thromboxane formation prevents endotoxin-induced renal fibrin deposition in jaundiced rats. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221642
Kangasaho M et al. Formation of thromboxane B2 by platelets and concentrations of thromboxane B2 and 6-keto-prostaglandin F1 alpha in plasma after acute ethanol ingestion. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6303086