| MeSH term | MeSH ID | Detail |
|---|---|---|
| Intermittent Claudication | D007383 | 6 associated lipids |
| Jejunal Diseases | D007579 | 3 associated lipids |
| Keratitis | D007634 | 7 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Polycystic Kidney Diseases | D007690 | 12 associated lipids |
| Leiomyosarcoma | D007890 | 4 associated lipids |
| Leukemia, Lymphoid | D007945 | 18 associated lipids |
| Leukemia, Myeloid | D007951 | 52 associated lipids |
| Leukopenia | D007970 | 9 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Liver Cirrhosis, Biliary | D008105 | 12 associated lipids |
| Liver Cirrhosis, Experimental | D008106 | 36 associated lipids |
| Liver Diseases, Alcoholic | D008108 | 13 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
| Lung Diseases, Obstructive | D008173 | 10 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lupus Nephritis | D008181 | 8 associated lipids |
| Macular Edema | D008269 | 3 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lumley P et al. | Maximal blockade of TxA2 without compromised PGI2 formation; a superior profile of the TxA2 receptor blocking drug GR32191 over aspirin. | 1991 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:1825385 |
| Patrono C et al. | Thromboxane-dependent platelet activation as a transducer of enhanced risk of coronary and cerebral thrombosis. | 1991 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:1825389 |
| Zhao Y et al. | Thromboxane and leukotriene generation by mononuclearcytes from cardiac transplant patients. | 1991 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:1825392 |
| Vial JH et al. | Rebound elevation in urinary thromboxane B2 and 6-keto-PGF1 alpha excretion after aspirin withdrawal. | 1991 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:1825534 |
| Ritter JM et al. | On the mechanism of the prolonged action in man of GR32191, a thromboxane receptor antagonist. | 1991 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:1825568 |
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| Lecompte T et al. | Radioimmunoassay for 11-dehydro-thromboxane B2 using an iodinated ligand: preliminary applications to human fluids. | 1987 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2960162 |
| Catella F et al. | Analysis of multiple thromboxane metabolites in plasma and urine. | 1987 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2960166 |
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| Yoshida T et al. | Improvement of renal function with selective thromboxane A2 synthetase inhibitor, DP-1904 in lupus nephritis. | 1997 | Adv. Exp. Med. Biol. | pmid:9561116 |
| Müller M | In vivo measurement of interstitial TxB2-concentrations in skeletal muscle during ischemia and reperfusion. | 1997 | Adv. Exp. Med. Biol. | pmid:9561122 |
| Arbogast E et al. | Intrauterine eicosanoid production in uncomplicated and hypertensive pregnancies: alterations of placental 12-hydroxyeicosatetraenoic acid. | 1997 | Adv. Exp. Med. Biol. | pmid:9561182 |
| Moncada S and Whittle BJ | Biological actions of prostacyclin and its pharmacological use in platelet studies. | 1985 | Adv. Exp. Med. Biol. | pmid:3010671 |
| Bourgeois N et al. | Effects of endotoxin on hemodynamics of isolated dog kidney. | 1987 | Adv. Exp. Med. Biol. | pmid:3303858 |
| Flynn JT and Demling RH | Inhibition of endogenous thromboxane synthesis by exogenous prostacyclin during endotoxemia in conscious sheep. | 1982 | Adv Shock Res | pmid:6753534 |
| Lefer AM and Crossley K | Mechanisms of the optimal protective effects of ibuprofen in acute myocardial ischemia. | 1980 | Adv Shock Res | pmid:7304314 |
| Zamecnik J et al. | Concentrations of thromboxane B2 and 6-oxo-prostaglandin F1 alpha in amniotic fluid, decidual tissue, and placenta in the later stages of pregnancy in the rat. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6990719 |
| Frame MH et al. | Inhibition of acid secretion from the rat-isolated gastric mucosa by arachidonic acid and identification of major metabolites. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6990724 |
| Sanger GJ and Bennett A | Trimethoquinol selectively antagonizes contractions of rat gastric fundus to TXB2 and epoxymethano analogs of PGH2. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6103666 |
| Harris RH et al. | Relationship of TXB2 and 6-keto PGF1 alpha to the hemodynamic changes during baboon endotoxic shock. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6768234 |
| Güllner HG et al. | The principal metabolites of arachidonic acid are overproduced in Bartter's syndrome. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6892749 |
| Schlondorff D and Folkert VW | Prostaglandin synthesis in glomeruli from rats with unilateral ureteral obstruction. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7369028 |
| Van Praag D and Farber SJ | Prostaglandin biosynthesis in normal and ureteral obstructed rabbit kidney; formation of a novel metabolite. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7369029 |
| Lindgren JA et al. | Effects of platelet aggregation and adenosine 3':5'-monophosphate on the synthesis of thromboxane B2 in human platelets. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6247886 |
| Kot PA et al. | Modification of the cardiovascular actions of prostaglandins by thromboxane B2. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7369035 |
| Gorman RR | Biochemical and pharmacological evaluation of thromboxane synthetase inhibitors. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6247892 |
| Friedman LS et al. | Thromboxane B2 inhibits the pulmonary metabolism of PGE2 in the anesthetized dog. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7369063 |
| Bishai I and Coceani F | Metabolism of PGH2 in the feline brain. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7376980 |
| Katori M et al. | Changes of prostaglandin and thromboxane levels in pleural fluid of rat carrageenin-induced pleurisy. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7377020 |
| Crutchley DJ et al. | Potentiation of thromboxane B2 release from guinea pig lung during anaphylaxis following exposure to 100% O2. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7377022 |
| Morris HG and Sherman NA | Prostaglandin-like substances in urine of asthmatic patients. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7377024 |
| Schoene NW et al. | Effects of diets varying in fat and P/S ratio on arachidonic acid metabolism in human platelets. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7377026 |
| Patrono C et al. | Radioimmunoassay of serum thromboxane B2: a simple method of assessing pharmacologic effects on platelet function. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7386257 |
| Langs DA et al. | Thromboxane molecules are not hairpin conformers. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7386281 |
| Bailey JM | Essential fatty acid requirements and metabolism of cells in tissue culture. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:7386288 |
| Feinstein MB et al. | Serine-esterase (protease) inhibitors block stimulus-induced mobilization of arachidonate in platelets. | 1980 | Adv Prostaglandin Thromboxane Res | pmid:6770602 |