Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
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Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kiberd BA | The functional and structural changes of the glomerulus throughout the course of murine lupus nephritis. | 1992 | J. Am. Soc. Nephrol. | pmid:1450369 |
| Fujii S et al. | L-arginine reverses p47phox and gp91phox expression induced by high salt in Dahl rats. | 2003 | Hypertension | pmid:14504257 |
| Vani G et al. | Histone H1 modulates immune status in experimental breast cancer. | 2003 | Chemotherapy | pmid:14504437 |
| Tanaka Y et al. | Effects of exercise on platelet and aortic functions in aged rats. | 2003 | Acta Physiol. Scand. | pmid:14510779 |
| Rossoni G et al. | Nitric oxide-releasing aspirin inhibits vasoconstriction in perfused tail artery of normotensive and spontaneously hypertensive rats. | 2003 | Eur. J. Pharmacol. | pmid:14512099 |
| Beck-Speier I et al. | Sulfur-related air pollutants induce the generation of platelet-activating factor, 5-lipoxygenase- and cyclooxygenase-products in canine alveolar macrophages via activation of phospholipases A2. | 2003 | Prostaglandins Other Lipid Mediat. | pmid:14518563 |
| Takase B et al. | Effect of diltiazem on silent ischemic episodes, plasma bradykinin and prostaglandin metabolism. | 1992 | Int. J. Cardiol. | pmid:1452374 |
| Peng W et al. | Effects of sustained ligustrazine on hemorrheology in patients with chronic pulmonary heart disease. | 1992 | J. Tongji Med. Univ. | pmid:1453503 |
| Rota S et al. | Methylprednisolone dosage effects on peripheral lymphocyte subpopulations and eicosanoid synthesis. | 1992 | Kidney Int. | pmid:1453591 |
| Li JS et al. | [Change in intestinal free radical and prostaglandin metabolism in the aged rats with pneumococcus pneumonia]. | 2003 | Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | pmid:14552688 |
| Dotevall A et al. | Cigarette smoking increases thromboxane A2 formation without affecting platelet survival in young healthy females. | 1992 | Thromb. Haemost. | pmid:1455405 |
| Kivioja A et al. | Platelet activation during acute phase after multiple trauma. | 1992 | Ann Chir Gynaecol | pmid:1456710 |
| Pearl JM et al. | Leukocyte-depleted reperfusion of transplanted human hearts: a randomized, double-blind clinical trial. | 1992 Nov-Dec | J. Heart Lung Transplant. | pmid:1457432 |
| Wolfram RM et al. | Narghile (water pipe) smoking influences platelet function and (iso-)eicosanoids. | 2003 | Life Sci. | pmid:14575812 |
| Nagano H et al. | Effects of a human urinary kininogenase (SK-827) on cerebral microcirculation after glass bead-induced cerebral embolism in rabbits. | 1992 Sep-Oct | In Vivo | pmid:1457742 |
| Chouinard ML et al. | Pharmacokinetics and biochemical efficacy of pirmagrel, a thromboxane synthase inhibitor, in renal allograft recipients. | 1992 | Clin. Pharmacol. Ther. | pmid:1458769 |
| Resnick DK et al. | Regional and temporal changes in prostaglandin E2 and thromboxane B2 concentrations after spinal cord injury. | 2001 Nov-Dec | Spine J | pmid:14588301 |
| Resnick DK et al. | Selective cyclooxygenase 2 inhibition lowers spinal cord prostaglandin concentrations after injury. | 2001 Nov-Dec | Spine J | pmid:14588302 |
| Kankuri E et al. | Effects of phenacetin and its metabolite p-phenetidine on COX-1 and COX-2 activities and expression in vitro. | 2003 | Thromb. Res. | pmid:14592552 |
| Zhang C et al. | Inflammation is involved in the organ damage induced by sinoaortic denervation in rats. | 2003 | J. Hypertens. | pmid:14597858 |
| Wang ZF et al. | The role of inflammatory mediators in severe acute pancreatitis and regulation of glucocorticoids. | 2003 | HBPD INT | pmid:14599960 |
| De León EJ et al. | A new chloroquinolinyl chalcone derivative as inhibitor of inflammatory and immune response in mice and rats. | 2003 | J. Pharm. Pharmacol. | pmid:14604476 |
| Tanaka S et al. | High dose of inhaled fluticasone reduces high levels of urinary leukotriene E4 in the early morning in mild and moderate nocturnal asthma. | 2003 | Chest | pmid:14605047 |
| Dong WG et al. | Ameliorative effects of sodium ferulate on experimental colitis and their mechanisms in rats. | 2003 | World J. Gastroenterol. | pmid:14606091 |
| von Aulock S et al. | Granulocyte colony-stimulating factor (filgrastim) treatment primes for increased ex vivo inducible prostanoid release. | 2004 | J. Pharmacol. Exp. Ther. | pmid:14610236 |
| Yokoyama Y et al. | Role of thromboxane in producing portal hypertension following trauma-hemorrhage. | 2003 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:14613921 |
| Grekas D et al. | Acute cyclosporin A renal dysfunction in dogs reversed by calcium antagonists and antiplatelet agents. | 1992 | Ren Fail | pmid:1462000 |
| Ohsaki S et al. | Effect of prostaglandin E1 on graft function of kidneys from living related donors. | 1992 | Transpl. Int. | pmid:14621746 |
| Schütz A et al. | Allogeneic heart transplantation following xenogeneic bridging. | 1992 | Transpl. Int. | pmid:14621808 |
| Yamada K et al. | New morphological changes induced by FK506 in a short period in the rat kidney and the effect of superoxide dismutase and OKY-046 on THEM: the relationship of FK506 nephrotoxicity to lipid peroxidation and change in production of thromboxane A2 in the kidney. | 1992 | Transpl. Int. | pmid:14621878 |
| Mennander A et al. | Chronic rejection of rat aortic allografts: effect of inhibition of the thromboxane cascade. | 1992 | Transpl. Int. | pmid:14621882 |
| Lyck F et al. | [Thrombocyte aggregation and serum thromboxane B2 in patients with unstable angina pectoris treated with diltiazem or verapamil]. | 1992 | Ugeskr. Laeg. | pmid:1462402 |
| Tsipas G and Morphake P | Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity. | 2003 | J. Nutr. Biochem. | pmid:14629893 |
| Moriguchi A et al. | Antithrombotic effects of FK419, a novel nonpeptide platelet GPIIb/IIIa antagonist, in a guinea pig photochemically induced middle cerebral artery thrombosis model: comparison with ozagrel and argatroban. | 2004 | J. Pharmacol. Exp. Ther. | pmid:14634048 |
| Yi H et al. | [Protective effect of selective cyclooxygenase-2 inhibitor on alcohol-induced liver injury in rats]. | 2003 | Zhonghua Gan Zang Bing Za Zhi | pmid:14636441 |
| Terres W et al. | Prevalence and mechanism of streptokinase-induced platelet stimulation. Effect of acetylsalicylic acid. | 1992 | Eur. Heart J. | pmid:1464340 |
| De Keijzer MH and Provoost AP | Effect of protein intake and unilateral nephrectomy on renal function and eicosanoid excretion in rats. | 1992 | Miner Electrolyte Metab | pmid:1465043 |
| Eder K et al. | Conjugated linoleic acids lower the release of eicosanoids and nitric oxide from human aortic endothelial cells. | 2003 | J. Nutr. | pmid:14652352 |
| Minuz P et al. | Determinants of platelet activation in human essential hypertension. | 2004 | Hypertension | pmid:14656953 |
| Petric R et al. | Amelioration of experimental cyclosporine nephrotoxicity by calcium channel inhibition. | 1992 | Transplantation | pmid:1465778 |
| Eldar M et al. | Bradykinin level in the great cardiac vein during balloon angioplasty of the left anterior descending coronary artery. | 1992 | Am. J. Cardiol. | pmid:1466338 |
| Xia Z et al. | Antioxidant therapy with Salvia miltiorrhiza decreases plasma endothelin-1 and thromboxane B2 after cardiopulmonary bypass in patients with congenital heart disease. | 2003 | J. Thorac. Cardiovasc. Surg. | pmid:14666012 |
| Böhm E et al. | 11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils. | 2004 | J. Biol. Chem. | pmid:14668348 |
| Arrebola MM et al. | In vitro effects of clopidogrel on the platelet-subendothelium interaction, platelet thromboxane and endothelial prostacyclin production, and nitric oxide synthesis. | 2004 | J. Cardiovasc. Pharmacol. | pmid:14668571 |
| Freitas CF et al. | Role of endothelin-1 and thromboxane A2 in the pulmonary hypertension induced by heparin-protamine interaction in anesthetized dogs. | 2004 | J. Cardiovasc. Pharmacol. | pmid:14668575 |
| Sánchez-Muniz FJ et al. | Platelet aggregation, thromboxane production and thrombogenic ratio in postmenopausal women consuming high oleic acid-sunflower oil or palmolein. | 2003 | Eur J Nutr | pmid:14673602 |
| Lin YL and Wang CT | Activation of human platelets by the rabbit anticardiolipin antibodies. | 1992 | Blood | pmid:1467520 |
| Sheu JR et al. | Inhibitory mechanisms of metallothionein on platelet aggregation in in vitro and platelet plug formation in in vivo experiments. | 2003 | Exp. Biol. Med. (Maywood) | pmid:14681547 |
| de La Puerta Vázquez R et al. | Effects of different dietary oils on inflammatory mediator generation and fatty acid composition in rat neutrophils. | 2004 | Metab. Clin. Exp. | pmid:14681843 |
| Gutiérrez DÃaz JA et al. | Interaction of platelets with subendothelium in rats treated with PCA-4230, a new antithrombotic agent. Effect of PCA-4230 on experimental thrombosis. | 1992 | Haemostasis | pmid:1468723 |