Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Blood Platelet Disorders D001791 12 associated lipids
Hypertension, Renovascular D006978 10 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Purpura, Schoenlein-Henoch D011695 5 associated lipids
Behcet Syndrome D001528 7 associated lipids
Escherichia coli Infections D004927 17 associated lipids
Migraine Disorders D008881 11 associated lipids
Pregnancy Complications, Cardiovascular D011249 11 associated lipids
Thrombasthenia D013915 4 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Disseminated Intravascular Coagulation D004211 7 associated lipids
Uveitis D014605 14 associated lipids
Byssinosis D002095 11 associated lipids
Enteritis D004751 8 associated lipids
Pneumonia, Aspiration D011015 3 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Arthus Reaction D001183 8 associated lipids
Angina Pectoris D000787 27 associated lipids
Angina, Unstable D000789 14 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Agnoli GC et al. Volume-induced natriuresis in healthy women: renal metabolism of prostacyclin and thromboxane, and physiological role of prostanoids. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11237476
Yu J and Hu WS [Effects of neferine on platelet aggregation in rabbits]. 1997 Yao Xue Xue Bao pmid:11243209
Praticò D et al. Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11248083
Carvalho CR et al. Antigen-induced bronchial hyperreactivity and bronchopulmonary inflammation in rats: effect of TNF receptor binding protein. 2001 Exp. Lung Res. pmid:11258800
de la Riva IJ et al. Effect of oral L-arginine administration for three weeks in two kidney-two clip hypertensive rats. 2000 Arch. Physiol. Biochem. pmid:11262599
Oikawa K et al. Elimination of Kupffer cells suppresses activation of nuclear factor kappa B and production of cytokines and eicosanoids in non-heart-beating donors. 2001 Feb-Mar Transplant. Proc. pmid:11267090
Uchiyama M et al. Comparison between nonpulsatile and pulsatile machine perfusion preservation in liver transplantation from non-heart-beating donors. 2001 Feb-Mar Transplant. Proc. pmid:11267136
Torras J et al. Renal protective effect of liposomed superoxide dismutase in an experimental warm ischemia model. 1994 Transpl. Int. pmid:11271283
Skovronsky DM et al. Amyloid precursor protein and amyloid beta peptide in human platelets. Role of cyclooxygenase and protein kinase C. 2001 J. Biol. Chem. pmid:11278299
Komers R et al. Immunohistochemical and functional correlations of renal cyclooxygenase-2 in experimental diabetes. 2001 J. Clin. Invest. pmid:11285308
Chen CY and Lin TH Effects of nickel chloride on human platelets: enhancement of lipid peroxidation, inhibition of aggregation and interaction with ascorbic acid. 2001 J. Toxicol. Environ. Health Part A pmid:11289317
Clayton HA et al. A coculture model of intrahepatic islet transplantation: activation of Kupffer cells by islets and acinar tissue. 2001 Jan-Feb Cell Transplant pmid:11294466
Lim JW et al. Nuclear factor-kappaB regulates cyclooxygenase-2 expression and cell proliferation in human gastric cancer cells. 2001 Lab. Invest. pmid:11310828
Guyton K et al. Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation. 2001 J. Leukoc. Biol. pmid:11310850
Turull A et al. Acute effects of the anti-inflammatory cyclooxygenase-2 selective inhibitor, flosulide, on renal plasma flow and glomerular filtration rate in rats. 2001 Inflammation pmid:11321358
Rilantono LI et al. Dietary antioxidative potential in arteries. 2000 Clin. Hemorheol. Microcirc. pmid:11321428
Hu DH [Effects of taurine enhancement of synthesis of TxA2 and PGI2 in cultured intra-pulmonary arteriolar smooth muscle cells under acute hypoxia]. 1998 Sheng Li Xue Bao pmid:11324559
Kijima Y et al. Transcardiac 8-iso-prostaglandin F(2 alpha)generation from acute myocardial infarction heart: insight into abrupt reperfusion and oxidant stress. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11334551
Karamouzis M et al. In situ microdialysis of intramuscular prostaglandin and thromboxane in contracting skeletal muscle in humans. 2001 Acta Physiol. Scand. pmid:11350265
Cracowski JL et al. Enhanced in vivo lipid peroxidation in scleroderma spectrum disorders. 2001 Arthritis Rheum. pmid:11352247
Burch RM et al. Vasopressin stimulates thromboxane synthesis in the toad urinary bladder: effects of imidazole. 1979 J. Pharmacol. Exp. Ther. pmid:113526
Wang LL et al. Effects of MN-9202 on platelet aggregation, 5-HT release, TXB2 synthesis, and calcium mobilization in rabbit platelets in vitro. 2000 Acta Pharmacol. Sin. pmid:11360670
Zhang T et al. [Clinical observation on preventing and treating coronary atherosclerotic heart disease with tongmai jiangzhi oral liquid]. 1998 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11367649
Yu Y et al. [Changes of prostaglandins in kidney tissue in gentamicin-induced acute renal tubular injury in rats]. 1998 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:11367732
Franconi F et al. Effect of gamma-hydroxybutyric acid on human platelet aggregation in vitro. 2001 Thromb. Res. pmid:11369419
Loew D et al. Investigations on the pharmacokinetic properties of Harpagophytum extracts and their effects on eicosanoid biosynthesis in vitro and ex vivo. 2001 Clin. Pharmacol. Ther. pmid:11372004
Yoshinari D et al. Effects of a dual inhibitor of tumor necrosis factor-alpha and interleukin-1 on lipopolysaccharide-induced lung injury in rats: involvement of the p38 mitogen-activated protein kinase pathway. 2001 Crit. Care Med. pmid:11373433
Ogata K et al. Attenuation of ischemia and reperfusion injury of canine livers by inhibition of type II phospholipase A2 with LY329722. 2001 Transplantation pmid:11374398
Katoh M et al. Inhibitory effects of TA-993 and its metabolite MB3 on platelet activation induced by collagen and U-46619 in human platelets. 2001 Biol. Pharm. Bull. pmid:11379769
Miyake K et al. Effects of olopatadine hydrochloride on the increase of histamine and peptide-leukotrienes concentrations in nasal lavage fluid following the antigen-antibody reaction in actively sensitized guinea pigs. 2001 Jpn. J. Pharmacol. pmid:11388650
Cantaro S et al. Urinary excretion of vasoactive substances in chronic renal failure. 2001 Clin. Nephrol. pmid:11393385
Tuppo EE et al. Sign of lipid peroxidation as measured in the urine of patients with probable Alzheimer's disease. 2001 Brain Res. Bull. pmid:11397549
Sontag W Release of mediators by DMSO-differentiated HL-60 cells exposed to electric interferential current and the requirement of biochemical prestimulation. 2001 Int. J. Radiat. Biol. pmid:11403712
Norio K et al. Eicosanoids and delayed graft function in human renal transplantation. 2001 Transplant. Proc. pmid:11406239
Karamouzis M et al. The response of muscle interstitial prostaglandin E(2)(PGE(2)), prostacyclin I(2)(PGI(2)) and thromboxane A(2)(TXA(2)) levels during incremental dynamic exercise in humans determined by in vivo microdialysis. 2001 Apr-May Prostaglandins Leukot. Essent. Fatty Acids pmid:11418021
Okita M et al. Effect of arachidonic acid-rich oil on lipids and arachidonate metabolites in ethanol- treated rats. 2001 Apr-May Prostaglandins Leukot. Essent. Fatty Acids pmid:11418023
Feldman M et al. Effects of low-dose aspirin on serum C-reactive protein and thromboxane B2 concentrations: a placebo-controlled study using a highly sensitive C-reactive protein assay. 2001 J. Am. Coll. Cardiol. pmid:11419884
Engström K et al. Effect of low-dose aspirin in combination with stable fish oil on whole blood production of eicosanoids. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11427037
Oketani K et al. In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production. 2001 Eur. J. Pharmacol. pmid:11430933
Minuz P et al. NCX4016 (NO-aspirin) inhibits thromboxane biosynthesis and tissue factor expression and activity in human monocytes. 2001 Jul-Aug Med. Sci. Monit. pmid:11433179
Gossmann J et al. Pathophysiology of cyclosporine-induced nephrotoxicity in humans: a role for nitric oxide? 2001 Kidney Blood Press. Res. pmid:11435743
Dubé JN et al. Characterization of a partial prostaglandin endoperoxide H synthase-1 deficiency in a patient with a bleeding disorder. 2001 Br. J. Haematol. pmid:11442478
Tran HS et al. Prostacyclin is neither sufficient alone nor necessary to cause pulmonary dysfunction: results from infusions of prostacyclin and antiprostacyclin antibody in porcine septic shock. 2001 Crit. Care Med. pmid:11445706
Coelho-Filho OR et al. Pravastatin reduces myocardial lesions induced by acute inhibition of nitric oxide biosynthesis in normocholesterolemic rats. 2001 Int. J. Cardiol. pmid:11461744
Wojakowski W and Gmiński J Plasma levels of von willebrand factor, endothelin-1, prostacyclin and thromboxane in children from families with high risk of premature coronary artery disease. 2001 Scand. J. Clin. Lab. Invest. pmid:11465346
Rosón MI et al. Serotonin hypersensitivity in aorta of two kidney-two clip hypertensive rats: calcium contribution and prostanoids-nitric oxide interactions. 2001 Arch. Physiol. Biochem. pmid:11471069
Catella-Lawson F et al. Oral glycoprotein IIb/IIIa antagonism in patients with coronary artery disease. 2001 Am. J. Cardiol. pmid:11472700
Zoja C et al. Mycophenolate mofetil combined with a cyclooxygenase-2 inhibitor ameliorates murine lupus nephritis. 2001 Kidney Int. pmid:11473648
Wu Y et al. [Clinical study on improving effect of Buyang Huanwu decoction on plasma thromboxane B2, 6-keto-prostaglandin F1 alpha, endothelin and calcitonin gene related peptide in primary nephrotic syndrome patients]. 1998 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11475715
Lang J et al. [Comparative study on effect of Panax notoginseng and ticlid in treating early diabetic nephropathy]. 1998 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:11475719