Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Hsu MF et al. Blockade of cytosolic phospholipase A(2) and 5-lipoxygenase activation in neutrophils by a natural isoflavanquinone abruquinone A. 2008 Eur. J. Pharmacol. pmid:18834875
Parsons JP et al. Airway inflammation in exercise-induced bronchospasm occurring in athletes without asthma. 2008 J Asthma pmid:18569228
Mitsopoulos P et al. Effectiveness of liposomal-N-acetylcysteine against LPS-induced lung injuries in rodents. 2008 Int J Pharm pmid:18694812
Larson MK et al. Effects of omega-3 acid ethyl esters and aspirin, alone and in combination, on platelet function in healthy subjects. 2008 Thromb. Haemost. pmid:18841286
Cheuk BL and Cheng SW Can local secretion of prostaglandin E2, thromboxane B2, and interleukin-6 play a role in ruptured abdominal aortic aneurysm? 2008 World J Surg pmid:17992560
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Kaehler S et al. S-ibuprofen effectively inhibits thromboxane B2 levels and platelet function in an experimental model of lipopolysaccharide-stimulated and non-stimulated whole blood. 2008 Pharmacology pmid:18043009
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Delgado-Lista J et al. Chronic dietary fat intake modifies the postprandial response of hemostatic markers to a single fatty test meal. 2008 Am. J. Clin. Nutr. pmid:18258620
Tanen DA et al. Comparison of oral aspirin versus topical applied methyl salicylate for platelet inhibition. 2008 Ann Pharmacother pmid:18698012
Nocun M et al. French maritime pine bark extract Pycnogenol reduces thromboxane generation in blood from diabetic male rats. 2008 Biomed. Pharmacother. pmid:17698319
Park MK et al. Antiplatelet and antithrombotic activity of indole-3-carbinol in vitro and in vivo. 2008 Phytother Res pmid:17724769
Rao CV et al. Pharmacokinetic and pharmacodynamic study of NO-donating aspirin in F344 rats. 2008 Int. J. Oncol. pmid:18813794
Rajec J et al. Biochemical evaluation of the antiplatelet effect of aspirin in patients at different levels of cardiovascular risk. 2008 Bratisl Lek Listy pmid:18814431
Bruce EC et al. Platelet thromboxane A2 secretion in patients with major depression responsive to electroconvulsive therapy. 2008 Psychosom Med pmid:18378867
Wooten JG et al. Cyclooxygenase expression and prostanoid production in pyloric and duodenal mucosae in dogs after administration of nonsteroidal anti-inflammatory drugs. 2008 Am. J. Vet. Res. pmid:18380576
Ruan KH et al. An active triple-catalytic hybrid enzyme engineered by linking cyclo-oxygenase isoform-1 to prostacyclin synthase that can constantly biosynthesize prostacyclin, the vascular protector. 2008 FEBS J. pmid:19021758
Jiang H et al. The midnight-noon ebb-flow point selection for 30 cases of acute ischemic cerebrovascular diseases. 2008 J Tradit Chin Med pmid:19004202