Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Sclerosis D012598 5 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Rhinitis D012220 10 associated lipids
Retinal Vein Occlusion D012170 2 associated lipids
Retinal Diseases D012164 4 associated lipids
Retinal Detachment D012163 10 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Lumley P et al. Maximal blockade of TxA2 without compromised PGI2 formation; a superior profile of the TxA2 receptor blocking drug GR32191 over aspirin. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825385
Mistry M and Nasjletti A Role of TXA2 in the pathogenesis of severe angiotensin II-salt hypertension. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526469
Koshihara Y and Fukuda M Appearance of metabolic activities for arachidonate during development of mouse embryos. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526512
Fuse I and Tai HH Regulation of arachidonate release by G-proteins and protein kinase C in human platelets. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526540
Houtz P and Tai HH Enzyme immunoassay of thromboxane B2 using immobilized hapten and enzyme amplification. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526560
FitzGerald GA et al. Thromboxane biosynthesis and antagonism in humans. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2959047
Nowak J and FitzGerald GA In vivo formation of prostacyclin and thromboxane A2 at the site of platelet-vascular interaction in humans. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2959050
De Caterina R et al. Characteristics of thromboxane production by the isolated-perfused rat heart. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2959082
Samhoun MN et al. Differential effect of vasoactive intestinal peptide on contractions induced by leukotriene D4, histamine, and acetylcholine in guinea pig lung parenchyma in vitro. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960144
Trimarco B et al. Indomethacin blunts the late phase of nitroglycerin-induced coronary vasodilatation in dogs. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159220
Shikano M et al. Effects of selective thromboxane synthetase inhibitor OKY-046 on plasma prostaglandins in patients with coronary artery disease during exercise. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159226
Prosdocimi M et al. Prostacyclin and thromboxane levels during cardiac ischemia in dogs. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159235
Fletcher JR et al. Thromboxane inhibition in gram-negative sepsis fails to improve survival. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221586
Socini A et al. Fish oil administration lowers prostacyclin production and the antiaggregatory activity of aortic walls more effectively than platelet aggregation and thromboxane in the rat. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221591
Hornstra G et al. Dietary-fat-induced changes in the formation of prostanoids of the 2 and 3 series in relation to arterial thrombosis (rat) and atherosclerosis (rabbit). 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221593
Tremoli E et al. North Karelian study: changes in dietary fat reduce thromboxane B2 formation by platelets only in male subjects--preliminary report. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221594
Basso N et al. Gastric mucosal prostaglandin generation in rats with stress ulcer. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221618
Foegh M et al. Prostacyclin and thromboxane release from human peritoneal macrophages. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221630
Westwick J et al. Inhibition of thromboxane formation prevents endotoxin-induced renal fibrin deposition in jaundiced rats. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221642
Kangasaho M et al. Formation of thromboxane B2 by platelets and concentrations of thromboxane B2 and 6-keto-prostaglandin F1 alpha in plasma after acute ethanol ingestion. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6303086