Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Acidosis D000138 13 associated lipids
Pain, Postoperative D010149 13 associated lipids
Uveitis D014605 14 associated lipids
Angina, Unstable D000789 14 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Carotid Stenosis D016893 15 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Thrombocytopenia D013921 15 associated lipids
Neutropenia D009503 15 associated lipids
Choline Deficiency D002796 16 associated lipids
Ventricular Fibrillation D014693 16 associated lipids
Ulcer D014456 16 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Atrial Fibrillation D001281 16 associated lipids
Blister D001768 16 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Wasserman MA and Griffin RL Thromboxane B2--comparative bronchoactivity in experimental systems. 1977 Eur. J. Pharmacol. pmid:590340
Poyser NL Identification of thromboxane B2 in guinea-pig uterine homogenates. 1977 Experientia pmid:590434
Fitzpatrick FA et al. A radioimmunoassay for thromboxane B2. 1977 Anal. Biochem. pmid:907115
Murota SI et al. The effects of thromboxane B2 and 6-ketoprostaglandin F1alpha on cultured fibroblasts. 1977 Biochim. Biophys. Acta pmid:911847
Roberts LJ et al. Metabolism of thromboxane B2 in man. Identification of the major urinary metabolite. 1977 J. Biol. Chem. pmid:914816
Ali M et al. Synthesis of prostaglandin D2 and thromboxane B2 by human platelets. 1977 Thromb. Res. pmid:918907
Burka JF and Garland LG A possible modulatory role for prostacyclin (PGI2) INIgGa-induced release of slow-reacting substance of anaphylaxis in rats. 1977 Br. J. Pharmacol. pmid:339980
Knapp HR et al. Ionophores stimulate prostaglandin and thromboxane biosynthesis. 1977 Proc. Natl. Acad. Sci. U.S.A. pmid:270668
Mitchell MD et al. Possible role for prostacyclin in human parturition. 1978 Prostaglandins pmid:373020
Goldstein IM et al. Thromboxane generation by human peripheral blood polymorphonuclear leukocytes. 1978 J. Exp. Med. pmid:702055
Anhut H et al. Pharmacological modification of thromboxane and prostaglandin release in cardiac anaphylaxis. 1978 Prostaglandins pmid:704912
Nelson NA et al. Synthesis of thromboxane B2 metabolites. 1978 Prostaglandins pmid:704927
Marion J and Wolfe LS Increase in vivo of unesterified fatty acids, prostaglandin F2 alpha but not thromboxane B2 in rat brain during drug induced convulsions. 1978 Prostaglandins pmid:704928
Kitchen EA et al. Chemotactic activity of thromboxane B2, prostaglandins and their metabolites for polymorphonuclear leucocytes. 1978 Prostaglandins pmid:704931
Sors H et al. Analytical methods for thromboxane B2 measurement and validation of radioimmunoassay by gas liquid chromatography-mass spectrometry. 1978 Prostaglandins pmid:704933
Turk J et al. Fluorescent derivatives of prostaglandins and thromboxanes for liquid chromatography. 1978 Prostaglandins pmid:704934
Raz A and Aharony D Prostaglandin biosynthesis in platelets: demonstration and role of prostaglandin H2 leads to E2 isomerase. 1978 Res. Commun. Chem. Pathol. Pharmacol. pmid:705027
Fitzpatrick FA and Gorman RR A comparison of imidazole and 9,11-azoprosta-5,13-dienoic acid. Two selective thromboxane synthetase inhibitors. 1978 Biochim. Biophys. Acta pmid:629996
Malik KU Prostaglandin-mediated inhibition of the vasoconstrictor responses of the isolated perfused art splenic vasculature to adrenergic stimuli. 1978 Circ. Res. pmid:27321
Hamberg M et al. A method for measurement of platelet regeneration in man. 1978 Prostaglandins Med pmid:104315