| MeSH term | MeSH ID | Detail |
|---|---|---|
| Erectile Dysfunction | D007172 | 19 associated lipids |
| Infarction, Middle Cerebral Artery | D020244 | 35 associated lipids |
| Stroke | D020521 | 32 associated lipids |
| Liver Cirrhosis, Biliary | D008105 | 12 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipoproteinemia Type IV | D006953 | 6 associated lipids |
| Nephrotic Syndrome | D009404 | 11 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Leukemia, Myeloid | D007951 | 52 associated lipids |
| Respiratory Distress Syndrome, Adult | D012128 | 15 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wen SH et al. | Ischemic postconditioning during reperfusion attenuates intestinal injury and mucosal cell apoptosis by inhibiting JAK/STAT signaling activation. | 2012 | Shock | pmid:22777122 |
| Jarvis GE et al. | A role for adhesion and degranulation-promoting adapter protein in collagen-induced platelet activation mediated via integrin α(2) β(1). | 2012 | J. Thromb. Haemost. | pmid:22103309 |
| Vazzana N et al. | Endogenous secretory RAGE in obese women: association with platelet activation and oxidative stress. | 2012 | J. Clin. Endocrinol. Metab. | pmid:22761461 |
| Zhou CB et al. | Decrease in inflammatory response does not prevent placental dysfunction after fetal cardiac bypass in goats. | 2012 | J. Thorac. Cardiovasc. Surg. | pmid:21821267 |
| Ramadan E et al. | Lamotrigine blocks NMDA receptor-initiated arachidonic acid signalling in rat brain: implications for its efficacy in bipolar disorder. | 2012 | Int. J. Neuropsychopharmacol. | pmid:21733229 |
| Cesari M et al. | Oxidative damage, platelet activation, and inflammation to predict mobility disability and mortality in older persons: results from the health aging and body composition study. | 2012 | J. Gerontol. A Biol. Sci. Med. Sci. | pmid:22389462 |
| Barberà -Cremades M et al. | P2X7 receptor-stimulation causes fever via PGE2 and IL-1β release. | 2012 | FASEB J. | pmid:22490780 |
| Wang Z et al. | Aspirin resistance in off-pump coronary artery bypass grafting. | 2012 | Eur J Cardiothorac Surg | pmid:21636287 |
| Su CL et al. | Inducible cyclooxygenase expression mediating hypoxia/reoxygenation-induced pulmonary vasoconstriction is attenuated by a cyclooxygenase inhibitor in rats. | 2012 | Transplant. Proc. | pmid:22564588 |
| Ames PR et al. | Aspirin insensitive thromboxane generation is associated with oxidative stress in type 2 diabetes mellitus. | 2012 | Thromb. Res. | pmid:22521214 |
| Andersson T et al. | Evaluation of the pharmacodynamics of acetylsalicylic acid 81 mg with or without esomeprazole 20 mg in healthy volunteers. | 2012 | Am J Cardiovasc Drugs | pmid:22631032 |
| Wang JW et al. | [Effects of puerarin on the vascular active factor related to cerebral vasospasm after aneurysm subarachnoid hemorrhage]. | 2012 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:22574584 |
| Li C et al. | Aspirin response variability after major orthopedic surgery. | 2012 | Thromb. Res. | pmid:22575418 |
| Sakai H et al. | Cardiopulmonary hemodynamic responses to the small injection of hemoglobin vesicles (artificial oxygen carriers) in miniature pigs. | 2012 | J Biomed Mater Res A | pmid:22615268 |
| Santostefano MJ et al. | Off-target platelet activation in macaques unique to a therapeutic monoclonal antibody. | 2012 | Toxicol Pathol | pmid:22552394 |
| Larsen SB et al. | Increased platelet aggregation and serum thromboxane levels in aspirin-treated patients with prior myocardial infarction. | 2012 | Thromb. Haemost. | pmid:22534977 |
| Skarke C et al. | Comparative impact on prostanoid biosynthesis of celecoxib and the novel nonsteroidal anti-inflammatory drug CG100649. | 2012 | Clin. Pharmacol. Ther. | pmid:22278334 |
| Ledwidge MT et al. | In vivo impact of prodrug isosorbide-5-nicotinate-2-aspirinate on lipids and prostaglandin D2: is this a new immediate-release therapeutic option for niacin? | 2012 | Atherosclerosis | pmid:22326030 |
| Chen C et al. | [Effects of extracts of Radix Scrophulariae on blood pressure in spontaneously hypertensive rats and the underlying mechanisms]. | 2012 | Zhong Xi Yi Jie He Xue Bao | pmid:22979933 |
| Etulain J et al. | Acidosis downregulates platelet haemostatic functions and promotes neutrophil proinflammatory responses mediated by platelets. | 2012 | Thromb. Haemost. | pmid:22159527 |
| Mayer AM et al. | Marine sponge Hymeniacidon sp. amphilectane metabolites potently inhibit rat brain microglia thromboxane B2 generation. | 2012 | Bioorg. Med. Chem. | pmid:22153874 |
| Yang D et al. | Effects of short- and long-term hypercholesterolemia on contrast-induced acute kidney injury. | 2012 | Am. J. Nephrol. | pmid:22189165 |
| Mustonen K et al. | Dose-response investigation of oral ketoprofen in pigs challenged with Escherichia coli endotoxin. | 2012 | Vet. Rec. | pmid:22735989 |
| Zhao Y et al. | [Effects of the effective components group of xiaoshuantongluo formula on rat acute blood stasis model]. | 2012 | Yao Xue Xue Bao | pmid:22812003 |
| Khandelwal AR et al. | Resveratrol and quercetin interact to inhibit neointimal hyperplasia in mice with a carotid injury. | 2012 | J. Nutr. | pmid:22718033 |
| Guo S et al. | Gastric mucosal damage in water immersion stress: mechanism and prevention with GHRP-6. | 2012 | World J. Gastroenterol. | pmid:22791951 |
| Wei X et al. | [Study of dahuangzhechong pills on anti-arterial thrombosis with the orthogonal design]. | 2012 | Zhong Yao Cai | pmid:22734422 |
| Qu C et al. | Effect of fenofibrate on the secretion of endothelium-derived contracting factors in hypertensive rats. | 2012 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:22776656 |
| Kaiser A et al. | [Effects of two different extracts of total saponins from Cicer arietinum on kidney of T2DM rats]. | 2012 | Yao Xue Xue Bao | pmid:22799041 |
| Macaluso M et al. | How biomarkers will change psychiatry. Part II: Biomarker selection and potential inflammatory markers of depression. | 2012 | J Psychiatr Pract | pmid:22805902 |
| Shih CY and Chou TC | The antiplatelet activity of magnolol is mediated by PPAR-β/γ. | 2012 | Biochem. Pharmacol. | pmid:22750553 |
| Rocca B et al. | The recovery of platelet cyclooxygenase activity explains interindividual variability in responsiveness to low-dose aspirin in patients with and without diabetes. | 2012 | J. Thromb. Haemost. | pmid:22471290 |
| Lee JJ et al. | Morusinol extracted from Morus alba inhibits arterial thrombosis and modulates platelet activation for the treatment of cardiovascular disease. | 2012 | J. Atheroscler. Thromb. | pmid:22472211 |
| Bruegel M et al. | Sepsis-associated changes of the arachidonic acid metabolism and their diagnostic potential in septic patients. | 2012 | Crit. Care Med. | pmid:22511130 |
| Totani L et al. | Prasugrel inhibits platelet-leukocyte interaction and reduces inflammatory markers in a model of endotoxic shock in the mouse. | 2012 | Thromb. Haemost. | pmid:22436970 |
| Matsuura E et al. | On aspirin treatment but not baseline thromboxane B2 levels predict adverse outcomes in patients with acute coronary syndromes. | 2012 | J. Thromb. Haemost. | pmid:22784188 |
| Salama MM et al. | Resistance to low-dose aspirin therapy among patients with acute coronary syndrome in relation to associated risk factors. | 2012 | J Clin Pharm Ther | pmid:23121257 |
| Thomason J et al. | Platelet cyclooxygenase expression in normal dogs. | 2011 Sep-Oct | J. Vet. Intern. Med. | pmid:21985141 |
| Alcott CJ et al. | Clinical and immunomodulating effects of ketamine in horses with experimental endotoxemia. | 2011 Jul-Aug | J. Vet. Intern. Med. | pmid:21745244 |
| Chakroun T et al. | The cyclooxygenase-1 C50T polymorphism is not associated with aspirin responsiveness status in stable coronary artery disease in Tunisian patients. | 2011 Jul-Aug | Genet Test Mol Biomarkers | pmid:21434767 |
| Saihkay HN et al. | Validating 123I-metaiodobenzylguanidine as a platelet marker for non-invasive imaging in rabbits. | 2011 Jan-Feb | J Pharmacol Toxicol Methods | pmid:20646985 |
| Brainard BM et al. | Effects of clopidogrel and aspirin on platelet aggregation, thromboxane production, and serotonin secretion in horses. | 2011 Jan-Feb | J. Vet. Intern. Med. | pmid:21143302 |
| Li CH et al. | [Effect of electroacupuncture at different acupoints on plasma TXB2 and 6-keto-PGF(1alpha), contents in dysmenorrhea rats]. | 2011 | Zhen Ci Yan Jiu | pmid:22073886 |
| Angiolillo DJ et al. | Impact of a fixed-dose combination of naproxen and esomeprazole magnesium on serum thromboxane B2 inhibition by low-dose aspirin over 5 days in healthy adults: a phase I, randomized, double-blind, placebo-controlled, noninferiority trial. | 2011 | Clin Ther | pmid:22078153 |
| Gonçalves LH et al. | Urinary 11-dehydro thromboxane B₂ levels in type 2 diabetic patients before and during aspirin intake. | 2011 | Clin. Chim. Acta | pmid:21510926 |
| Oates JC et al. | Selective cyclooxygenase-2 inhibitor suppresses renal thromboxane production but not proliferative lesions in the MRL/lpr murine model of lupus nephritis. | 2011 | Am. J. Med. Sci. | pmid:20924284 |
| Grove EL et al. | Effect of platelet turnover on whole blood platelet aggregation in patients with coronary artery disease. | 2011 | J. Thromb. Haemost. | pmid:20955349 |
| Moussa O et al. | Urinary thromboxane B2 and thromboxane receptors in bladder cancer: opportunity for detection and monitoring. | 2011 | Prostaglandins Other Lipid Mediat. | pmid:21983220 |
| Kleinbongard P et al. | Acute vasomotor paralysis and potential downstream effects of paclitaxel from stents implanted for saphenous vein aorto-coronary bypass stenosis. | 2011 | Basic Res. Cardiol. | pmid:21472462 |
| Lordkipanidzé M et al. | Heterogeneity in platelet cyclooxygenase inhibition by aspirin in coronary artery disease. | 2011 | Int. J. Cardiol. | pmid:20207433 |