Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Latex Hypersensitivity D020315 1 associated lipids
Stomach Volvulus D013277 1 associated lipids
Foot Rot D005535 1 associated lipids
Frostbite D005627 1 associated lipids
Strongyle Infections, Equine D013319 1 associated lipids
Basal Ganglia Hemorrhage D020145 1 associated lipids
Edema, Cardiac D004489 1 associated lipids
Osteoblastoma D018215 1 associated lipids
Radiculopathy D011843 1 associated lipids
Oligomenorrhea D009839 1 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Rittenhouse-Simmons S Differential activation of platelet phospholipases by thrombin and ionophore A23187. 1981 J. Biol. Chem. pmid:6783655
Galli C et al. Differential effects of dietary fatty acids on the accumulation of arachidonic acid and its metabolic conversion through the cyclooxygenase and lipoxygenase in platelets and vascular tissue. 1981 Lipids pmid:6783805
Rao GH et al. Effect of Amrinone, a cardiotonic drug, on hemodynamics and platelet function. 1981 Prostaglandins Med pmid:6784136
Strand JC et al. Effect of imidazole on renal function in unilateral ureteral-obstructed rat kidneys. 1981 Am. J. Physiol. pmid:6787931
Handin RI and Alexander RW Humoral heartache -- do platelets have a role? 1981 N. Engl. J. Med. pmid:7010170
Robertson RM et al. Thromboxane A2 in vasotonic angina pectoris: evidence from direct measurements and inhibitor trials. 1981 N. Engl. J. Med. pmid:7010173
Tyler HM et al. Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase. 1981 Lancet pmid:6110861
Vermylen J et al. Thromboxane synthetase inhibition as antithrombotic strategy. 1981 Lancet pmid:6112447
Feuerstein N et al. 3-deazaadenosine, a transmethylase inhibitor, suppresses the effect of lipopolysaccharide on release of prostacyclin and thromboxane. 1981 J. Pharm. Pharmacol. pmid:6115021
Fasce L et al. [Effects of glucocorticoids on the gastrointestinal tract of normal rats and rats deficient in endogenous prostaglandins]. 1981 Boll. Soc. Ital. Biol. Sper. pmid:7295403
Tada M et al. Elevation of thromboxane B2 levels in patients with classic and variant angina Pectoris. 1981 Circulation pmid:7296786
Rifkin BR and Tai HH Elevated thromboxane B2 levels in periodontal disease. 1981 J. Periodont. Res. pmid:6453981
Mehta J and Mehta P Significance of platelet function and thromboxane B2 levels across the human myocardial vascular bed. 1981 Acta Med. Scand. Suppl. pmid:6948499
Stenson WF et al. Metabolism of exogenous arachidonic acid by murine macrophage-like tumor cell lines. 1981 Prostaglandins pmid:6803301
Rubenstein MD et al. Platelet activation in clinical coronary artery disease and spasm. 1981 Am. Heart J. pmid:6455912
Walker ID et al. A double blind study of prostacyclin in cardiopulmonary bypass surgery. 1981 Br. J. Haematol. pmid:6457624
Capitanio A et al. Platelet abnormalities in renal transplantation. 1981 Proc Eur Dial Transplant Assoc pmid:6460244
Kelly KL and Laychock SG Prostaglandin synthesis and metabolism in isolated pancreatic islets of the rat. 1981 Prostaglandins pmid:6803305
Kinney EL and Demers LM Plasma 6 keto PGE1 alpha concentration in Raynaud's phenomenon. 1981 Prostaglandins Med pmid:6895673
Barnett AH et al. Circulating prostanoid levels, both basal and during the chlorpropamide alcohol flush, in non-insulin dependent diabetes. 1981 Clin. Endocrinol. (Oxf) pmid:6895721
She HS et al. Metabolism of prostaglandin endoperoxide by microsomes from cat lung. 1981 Prostaglandins pmid:6894797
Russell NH et al. Platelet adenine nucleotides and arachidonic acid metabolism in the myeloproliferative disorders. 1981 Thromb. Res. pmid:6794179
Beck N and Shaw JO Thromboxane B2 and prostaglandin E2 in the K+-depleted rat kidney. 1981 Am. J. Physiol. pmid:7468800
Hwang DH et al. In vitro and in vivo effects of ethanol on the formation of endoperoxide metabolites in rat platelets. 1981 Lipids pmid:6792442
Tulenko TN The actions of prostaglandins and cyclo-oxygenase inhibition on the resistance vessels supplying the human fetal placenta. 1981 Prostaglandins pmid:6794096
Ingerman-Wojenski C et al. Prostacyclin production in rabbit arteries in situ: inhibition by arachidonic acid-induced endothelial cell damage or by low-dose aspirin. 1981 Prostaglandins pmid:6789404
Williamson EM et al. Studies on the mechanism of action of 12-deoxyphorbolphenylacetate, a potent platelet aggregating tigliane ester. 1981 Biochem. Pharmacol. pmid:6794576
Ylikorkala O et al. Prostacyclin and thromboxane in diabetes. 1981 Br Med J (Clin Res Ed) pmid:6794795
Feuerstein N and Ramwell PW OKY-1581, a potential selective thromboxane synthetase inhibitor. 1981 Eur. J. Pharmacol. pmid:7195815
Satoh H et al. Influence of angiotensins (I, II & III) on prostaglandin production by minced rat renal medulla. 1981 Prostaglandins pmid:7197382
Boyd JA and Eling TE Prostaglandin release and the interaction of platelets with the pulmonary vasculature of rat and guinea pig. 1980 Jul 1-15 Thromb. Res. pmid:7003800
Patrono C et al. Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects. 1980 Feb 1-15 Thromb. Res. pmid:7368167
Koh H et al. A radioimmunoassay of thromboxane B2 with thromboxane B2-125I-tyramide and its application to the study on the thromboxane B2 formation during platelet aggregation. 1980 Feb 1-15 Thromb. Res. pmid:7368170
Kosaki G et al. The mechanism of the inhibitory effect of protease inhibitors on platelet aggregation and cellular synthesis of prostaglandins. I. The effect on the release of arachidonic acid from phospholipids. 1980 Dec 1-15 Thromb. Res. pmid:6785893
Spagnuolo PJ et al. Thromboxane A2 mediates augmented polymorphonuclear leukocyte adhesiveness. 1980 J. Clin. Invest. pmid:6772674
Best LC et al. The interrelationship between thromboxane biosynthesis, aggregation and 5-hydroxytryptamine secretion in human platelets in vitro. 1980 Thromb. Haemost. pmid:6773171
Stuart MJ et al. The influence of albumin and calcium on human platelet arachidonic acid metabolism. 1980 Blood pmid:6766753
Challis JR and Patrick JE The production of prostaglandins and thromboxanes in the feto-placental unit and their effects on the developing fetus. 1980 Semin. Perinatol. pmid:6992278
Ahnfelt-Rønne I et al. Macrophages from adjuvent arthritic rats preferentially synthetize prostacyclin. 1980 Agents Actions pmid:6992544
Gullner HG et al. Correction of increased prostacyclin synthesis in Bartter's syndrome by indomethacin treatment. 1980 Prostaglandins Med pmid:6994153
Crutchley DJ et al. Enhanced thromboxane B2 release from challenged guinea pig lung after oxygen exposure. 1980 Am. Rev. Respir. Dis. pmid:6155814
Cella G et al. In vivo platelet release reaction in patients with heart valve prosthesis. 1980 Haemostasis pmid:6157609
Best LC et al. Lanthanum stimulates the accumulation of cyclic AMP and inhibits secretion and thromboxane B2 formation in human platelets. 1980 Biochim. Biophys. Acta pmid:6251913
Zapol WM et al. Plasma thromboxane and prostacyclin metabolites in sheep partial cardiopulmonary bypass. 1980 Trans Am Soc Artif Intern Organs pmid:7018060
Güllner HG et al. Correction of increased prostacyclin production in Bartter's syndrome by indomethacin. 1980 Trans. Assoc. Am. Physicians pmid:7018063
Heggers JP et al. Evaluation of burn blister fluid. 1980 Plast. Reconstr. Surg. pmid:6770396
Wise WC et al. Protective effects of thromboxane synthetase inhibitors in rats in endotoxic shock. 1980 Circ. Res. pmid:7189697
Salmon JA Analysis of arachidonic acid metabolites by radioimmunoassay and physicochemical methods. 1980 Mater Med Pol pmid:7019588
Zamecnik J et al. Concentrations of thromboxane B2 and 6-oxo-prostaglandin F1 alpha in amniotic fluid, decidual tissue, and placenta in the later stages of pregnancy in the rat. 1980 Adv Prostaglandin Thromboxane Res pmid:6990719
Mathé AA et al. Increased content of immunoreactive prostaglandin E in cerebrospinal fluid of patients with schizophrenia. 1980 Lancet pmid:6101355
Frame MH et al. Inhibition of acid secretion from the rat-isolated gastric mucosa by arachidonic acid and identification of major metabolites. 1980 Adv Prostaglandin Thromboxane Res pmid:6990724
Mestel F et al. Severe bleeding associated with defective thromboxane synthetase. 1980 Lancet pmid:6101498
Pareti FI et al. Platelets and the vessel wall: how much aspirin? 1980 Lancet pmid:6101829
Sanger GJ and Bennett A Trimethoquinol selectively antagonizes contractions of rat gastric fundus to TXB2 and epoxymethano analogs of PGH2. 1980 Adv Prostaglandin Thromboxane Res pmid:6103666
Zahavi J et al. Enhanced in-vivo platelet release reaction, increased thromboxane synthesis, and decreased prostacyclin release after tourniquet ischaemia. 1980 Lancet pmid:6106784
Lefer AM and Crossley K Mechanisms of the optimal protective effects of ibuprofen in acute myocardial ischemia. 1980 Adv Shock Res pmid:7304314
Güllner HG et al. The principal metabolites of arachidonic acid are overproduced in Bartter's syndrome. 1980 Adv Prostaglandin Thromboxane Res pmid:6892749
Liggins GC et al. Production rates of prostaglandin F, 6-keto-PGF1 alpha and thromboxane B2 by perifused human endometrium. 1980 Prostaglandins pmid:6892962
Subbiah MT and Dietemeyer D Altered synthesis of prostaglandins in platelet and aorta from spontaneously diabetic Wistar rats. 1980 Biochem Med pmid:6893150
Ali M and McDonald JW Synthesis of thromboxane B2 and 6-keto-prostaglandin F1 alpha by bovine gastric mucosal and muscle microsomes. 1980 Prostaglandins pmid:6893365
Ohuchi K et al. Prostaglandin production by minced carrageenin granuloma tissue of rats and its inhibition by dexamethasone and cycloheximide. 1980 Prostaglandins Med pmid:6893750
Galli C et al. Effects of 8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxy carboxyl methoxy coumarin (AD6) on aggregation, arachidonic acid metabolism and thromboxane B2 formation in human platelets. 1980 Pharmacol Res Commun pmid:7393988
Chiabrando C et al. Quantitative determination of 6-keto-PGF1 alpha released by rat aorta: comparison of mass fragmentography and high resolution gas chromatography with electron capture detection. 1980 Prostaglandins pmid:6894036
Oka M and Manku MS Spironolactone decreases the formation of prostaglandins and related substances from arachidonic acid in rat vascular rings and human platelets. 1980 Prostaglandins Med pmid:7394062
Friedman LS et al. Thromboxane B2 inhibits the pulmonary metabolism of PGE2 in the anesthetized dog. 1980 Adv Prostaglandin Thromboxane Res pmid:7369063
Garfield RE et al. Gap junction formation in myometrium: control by estrogens, progesterone, and prostaglandins. 1980 Am. J. Physiol. pmid:7369350
Lewy RI Effect of elevated plasma-free fatty acids on thromboxane release in patients with coronary artery disease. 1980 Haemostasis pmid:7372200
Bishai I and Coceani F Metabolism of PGH2 in the feline brain. 1980 Adv Prostaglandin Thromboxane Res pmid:7376980
Galli C et al. Factors affecting brain prostaglandin formation. 1980 Adv Prostaglandin Thromboxane Res pmid:7376983
Blotman F et al. PGE2, PGF2 alpha, and TXB2 biosynthesis by human rheumatoid synovia. 1980 Adv Prostaglandin Thromboxane Res pmid:7377017
Powell WS Rapid extraction of oxygenated metabolites of arachidonic acid from biological samples using octadecylsilyl silica. 1980 Prostaglandins pmid:6258197
Katori M et al. Changes of prostaglandin and thromboxane levels in pleural fluid of rat carrageenin-induced pleurisy. 1980 Adv Prostaglandin Thromboxane Res pmid:7377020
Crutchley DJ et al. Potentiation of thromboxane B2 release from guinea pig lung during anaphylaxis following exposure to 100% O2. 1980 Adv Prostaglandin Thromboxane Res pmid:7377022
Morris HG and Sherman NA Prostaglandin-like substances in urine of asthmatic patients. 1980 Adv Prostaglandin Thromboxane Res pmid:7377024
Schoene NW et al. Effects of diets varying in fat and P/S ratio on arachidonic acid metabolism in human platelets. 1980 Adv Prostaglandin Thromboxane Res pmid:7377026
Smith EF et al. Influence of thromboxane inhibition on the severity of myocardial ischemia in cats. 1980 Can. J. Physiol. Pharmacol. pmid:7378931
Ellwood DA et al. Specific changes in the in vitro production of prostanoids by the ovine cervix at parturition. 1980 Prostaglandins pmid:7384553
Lagarde M et al. Nicergoline, an anti-aggregating agent which inhibits release of arachidonic acid from human platelet phospholipids. 1980 Prostaglandins pmid:7384555
Patrono C et al. Radioimmunoassay of serum thromboxane B2: a simple method of assessing pharmacologic effects on platelet function. 1980 Adv Prostaglandin Thromboxane Res pmid:7386257
Langs DA et al. Thromboxane molecules are not hairpin conformers. 1980 Adv Prostaglandin Thromboxane Res pmid:7386281
Lefer AM et al. Dissociation of vasoconstrictor and platelet aggregatory activities of thromboxane by carbocyclic thromboxane A2, a stable analog of thromboxane A2. 1980 Proc. Natl. Acad. Sci. U.S.A. pmid:6929517
Bailey JM Essential fatty acid requirements and metabolism of cells in tissue culture. 1980 Adv Prostaglandin Thromboxane Res pmid:7386288
Moretti RL and Lin CY Coronary vasoconstrictor extracted from blood plasma stimulates platelet lipoxidase activity. 1980 Prostaglandins pmid:6770419
Maggi FM et al. Prostaglandin synthetase activity in vascular tissue of male and female rats. 1980 Prostaglandins pmid:6770422
Feinstein MB et al. Serine-esterase (protease) inhibitors block stimulus-induced mobilization of arachidonate in platelets. 1980 Adv Prostaglandin Thromboxane Res pmid:6770602
Cook JA et al. Elevated thromboxane levels in the rat during endotoxic shock: protective effects of imidazole, 13-azaprostanoic acid, or essential fatty acid deficiency. 1980 J. Clin. Invest. pmid:7350199
Maclouf J et al. Interactions of prostaglandin H2 and thromboxane A2 with human serum albumin. 1980 Eur. J. Biochem. pmid:7408901
Hwang DW et al. Species variation in serum levels of prostaglandins and their precursor acids. 1980 Lipids pmid:7432104
Bolton HS et al. Prostaglandin synthesis by adult heart myocytes. 1980 J. Mol. Cell. Cardiol. pmid:7441771
Dejana E et al. Impaired thromboxane production by newly formed platelets after aspirin administration to thrombocytopenic rats. 1980 Br. J. Haematol. pmid:7448129
Ylikorkala O and Viinikka L Thromboxane A2 in pregnancy and puerperium. 1980 Br Med J pmid:7448530
Bone EA et al. The effects of strontium and calcium ions on 5-hydroxytryptamine secretion and thromboxane B2 biosynthesis in washed human platelets. 1980 Biochem. Soc. Trans. pmid:7450206
Mitchell MD Prostaglandins at parturition and in the neonatal infant. 1980 Biochem. Soc. Trans. pmid:7450282
Kent L et al. Differential response of articular chondrocyte populations to thromboxane B2 and analogs of prostaglandin cyclic endoperoxides. 1980 Prostaglandins pmid:7384546
McManus LM et al. Thromboxane B2 (TxB2) release during IgE anaphylaxis in the rabbit. 1980 J. Immunol. pmid:7430618
Best LC et al. The relationship between the production of thromboxane B2 and malondialdehyde by human blood platelets. 1980 Clin. Sci. pmid:7190885
Heggers JP et al. Histological demonstration of prostaglandins and thromboxanes in burned tissue. 1980 J. Surg. Res. pmid:6987462
Meyers KM et al. An evaluation of the arachidonate pathway of platelets from companion and food-producing animals, mink, and man. 1980 Thromb. Res. pmid:7209869
Vanderhoek JY et al. 15-hydroxy-5,8,11,13-eicosatetraenoic acid: A potent and selective inhibitor of platelet lipoxygenase. 1980 J. Biol. Chem. pmid:6771259
Ali M et al. Inhibition of human platelet cyclooxygenase by alpha-tocopherol. 1980 Prostaglandins Med pmid:6771778