| MeSH term | MeSH ID | Detail |
|---|---|---|
| Latex Hypersensitivity | D020315 | 1 associated lipids |
| Stomach Volvulus | D013277 | 1 associated lipids |
| Foot Rot | D005535 | 1 associated lipids |
| Frostbite | D005627 | 1 associated lipids |
| Strongyle Infections, Equine | D013319 | 1 associated lipids |
| Basal Ganglia Hemorrhage | D020145 | 1 associated lipids |
| Osteoblastoma | D018215 | 1 associated lipids |
| Edema, Cardiac | D004489 | 1 associated lipids |
| Radiculopathy | D011843 | 1 associated lipids |
| Erythromelalgia | D004916 | 1 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gross GJ and Moore J | Effect of COX-1/COX-2 inhibition versus selective COX-2 inhibition on coronary vasodilator responses to arachidonic acid and acetylcholine. | 2004 | Pharmacology | pmid:15161995 |
| Suzuki N et al. | Quantitative liquid chromatography-tandem mass spectrometric analysis of 11-dehydro TXB2 in urine. | 2004 | Prostaglandins Other Lipid Mediat. | pmid:15165035 |
| Toth B et al. | Insights into the role of interleukin-6 in the induction of hepatic injury after trauma-hemorrhagic shock. | 2004 | J. Appl. Physiol. | pmid:15298985 |
| Craft JA et al. | Increased platelet-derived microparticles in the coronary circulation of percutaneous transluminal coronary angioplasty patients. | 2004 | Blood Coagul. Fibrinolysis | pmid:15311156 |
| Ferroni P et al. | Platelet activation in type 2 diabetes mellitus. | 2004 | J. Thromb. Haemost. | pmid:15304032 |
| Di Nunno L et al. | Novel synthesis of 3,4-diarylisoxazole analogues of valdecoxib: reversal cyclooxygenase-2 selectivity by sulfonamide group removal. | 2004 | J. Med. Chem. | pmid:15369392 |
| Mak IT et al. | Cardiac pathologic effects of azidothymidine (AZT) in Mg-deficient mice. | 2004 | Cardiovasc. Toxicol. | pmid:15371632 |
| Valeri CR et al. | In vitro effects of poly-N-acetyl glucosamine on the activation of platelets in platelet-rich plasma with and without red blood cells. | 2004 | J Trauma | pmid:15280746 |
| Singer P and Wirth M | Can n-3 PUFA reduce cardiac arrhythmias? Results of a clinical trial. | 2004 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15253884 |
| Bruno A et al. | Serial urinary 11-dehydrothromboxane B2, aspirin dose, and vascular events in blacks after recent cerebral infarction. | 2004 | Stroke | pmid:14963281 |
| Kwak SH et al. | Effects of propofol on endotoxin-induced acute lung injury in rabbit. | 2004 | J. Korean Med. Sci. | pmid:14966342 |
| Scott G et al. | Lumiracoxib: pharmacokinetic and pharmacodynamic profile when coadministered with fluconazole in healthy subjects. | 2004 | J Clin Pharmacol | pmid:14747429 |
| Arrebola MM et al. | In vitro effects of clopidogrel on the platelet-subendothelium interaction, platelet thromboxane and endothelial prostacyclin production, and nitric oxide synthesis. | 2004 | J. Cardiovasc. Pharmacol. | pmid:14668571 |
| Freitas CF et al. | Role of endothelin-1 and thromboxane A2 in the pulmonary hypertension induced by heparin-protamine interaction in anesthetized dogs. | 2004 | J. Cardiovasc. Pharmacol. | pmid:14668575 |
| Cotter G et al. | Lack of aspirin effect: aspirin resistance or resistance to taking aspirin? | 2004 | Am. Heart J. | pmid:14760328 |
| Fan JG et al. | [Dynamic changes of plasma levels of prostacycline and thromboxane A2 and their correlation with the severity of hepatic injury in rats with nonalcoholic fatty liver disease]. | 2004 | Zhonghua Gan Zang Bing Za Zhi | pmid:15623379 |
| Vega-Ostertag M et al. | Intracellular events in platelet activation induced by antiphospholipid antibodies in the presence of low doses of thrombin. | 2004 | Arthritis Rheum. | pmid:15457460 |
| Noverr MC and Huffnagle GB | Regulation of Candida albicans morphogenesis by fatty acid metabolites. | 2004 | Infect. Immun. | pmid:15501745 |
| Rocca B et al. | Modulation of the expression and activity of cyclooxygenases in normal and accelerated erythropoiesis. | 2004 | Exp. Hematol. | pmid:15504548 |
| Chou DS et al. | Low concentration of oxidized low density lipoprotein suppresses platelet reactivity in vitro: an intracellular study. | 2004 | Lipids | pmid:15506238 |
| He W et al. | Effects of the Chinese drugs for activating blood circulation on plasma TXB2 and 6-keto-PGF1alpha contents in rabbits with glucocorticoid-induced femoral head necrosis. | 2004 | J Tradit Chin Med | pmid:15510809 |
| Chiang N et al. | Aspirin triggers antiinflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15471991 |
| Kawata K et al. | The effects of a selective cyclooxygenase-2 inhibitor on small bowel ischemia-reperfusion injury. | 2003 Nov-Dec | Hepatogastroenterology | pmid:14696445 |
| Lang I et al. | Heterogeneity of microvascular endothelial cells isolated from human term placenta and macrovascular umbilical vein endothelial cells. | 2003 | Eur. J. Cell Biol. | pmid:12751902 |
| Molina V et al. | Synergistic effect of D-003 and aspirin on experimental thrombosis models. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12711246 |
| ChavarrÃa ME et al. | Prostacyclin/thromboxane early changes in pregnancies that are complicated by preeclampsia. | 2003 | Am. J. Obstet. Gynecol. | pmid:12712098 |
| Dogné JM et al. | Pharmacological evaluation of the novel thromboxane modulator BM-567 (I/II). Effects of BM-567 on platelet function. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12538090 |
| Tanaka S et al. | High dose of inhaled fluticasone reduces high levels of urinary leukotriene E4 in the early morning in mild and moderate nocturnal asthma. | 2003 | Chest | pmid:14605047 |
| Pestel S et al. | Inhibition of prostaglandin D2 clearance in rat hepatocytes by the thromboxane receptor antagonists daltroban and ifetroban and the thromboxane synthase inhibitor furegrelate. | 2003 | Biochem. Pharmacol. | pmid:12906929 |
| De La Cruz P et al. | Effects of clopidogrel and ticlopidine on experimental diabetic ischemic retinopathy in rats. | 2003 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:12595963 |
| Uchida M et al. | Changes in cerebral microcirculation during and after abdominal aortic cross-clamping in rabbits: the role of thromboxane A2 receptor. | 2003 | Anesth. Analg. | pmid:12598238 |
| Zaitsu M et al. | Thromboxane synthesis is increased by upregulation of cytosolic phospholipase A2 and cyclooxygenase-2 in peripheral polymorphonuclear leukocytes during bacterial infection in childhood. | 2003 | Am. J. Hematol. | pmid:12555215 |
| Kirchheiner J et al. | Pharmacokinetics of diclofenac and inhibition of cyclooxygenases 1 and 2: no relationship to the CYP2C9 genetic polymorphism in humans. | 2003 | Br J Clin Pharmacol | pmid:12534640 |
| Cabrera DM et al. | A thromboxane A(2) system in the Atlantic stingray, Dasyatis sabina. | 2003 | Gen. Comp. Endocrinol. | pmid:12568793 |
| Nemr R et al. | Effects of nicotine on thromboxane/prostacyclin balance in myocardial ischemia. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12591002 |
| Eatman D et al. | Influences of prostanoids and nitric oxide on post-suspension hypotension in female Sprague-Dawley rats. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12591003 |
| Patel YM et al. | Evidence for a role for Galphai1 in mediating weak agonist-induced platelet aggregation in human platelets: reduced Galphai1 expression and defective Gi signaling in the platelets of a patient with a chronic bleeding disorder. | 2003 | Blood | pmid:12609843 |
| Hausman N et al. | Antenatal administration of celecoxib, a selective cyclooxygenase (COX)-2 inhibitor, appears to improve placental perfusion in the pregnant rabbit. | 2003 | Prostaglandins Other Lipid Mediat. | pmid:12611495 |
| Basta M et al. | F(ab)'2-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins. | 2003 | Nat. Med. | pmid:12612546 |
| Fiorucci S et al. | Gastrointestinal safety of NO-aspirin (NCX-4016) in healthy human volunteers: a proof of concept endoscopic study. | 2003 | Gastroenterology | pmid:12612897 |
| Vigorita MG et al. | Chiral 3,3'-(1,2-ethanediyl)-bis[2-(3,4-dimethoxyphenyl)-4-thiazolidinones] with anti-inflammatory activity. Part 11: evaluation of COX-2 selectivity and modelling. | 2003 | Bioorg. Med. Chem. | pmid:12614885 |
| Ersöz G et al. | Effect of sodium selenite treatment on platelet aggregation of streptozotocin-induced diabetic rats. | 2003 | Thromb. Res. | pmid:14698654 |
| Wu X et al. | Zileuton, a 5-lipoxygenase inhibitor, increases production of thromboxane A2 and platelet aggregation in patients with asthma. | 2003 | Am. J. Hematol. | pmid:12949886 |
| Reid G et al. | The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12835412 |
| Bosetti F et al. | Valproic acid down-regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase-1 and -2 in rat brain. | 2003 | J. Neurochem. | pmid:12694395 |
| Gama de Abreu M et al. | One-lung ventilation with high tidal volumes and zero positive end-expiratory pressure is injurious in the isolated rabbit lung model. | 2003 | Anesth. Analg. | pmid:12505956 |
| Tanaka Y et al. | Effects of exercise on platelet and aortic functions in aged rats. | 2003 | Acta Physiol. Scand. | pmid:14510779 |
| Sidhu P et al. | Tissue chamber model of acute inflammation in farm animal species. | 2003 | Res. Vet. Sci. | pmid:12507568 |
| Wolfram R et al. | Daily prickly pear consumption improves platelet function. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12878452 |
| Yu CC and Lai YL | Chronic hypoxia attenuates ischemia-reperfusion-induced increase in pulmonary vascular resistance. | 2003 | Life Sci. | pmid:12927588 |
| Zhuang HP et al. | [Effect of aspirin combined with perindopril on prostacyclin, thromboxone A2, and norepinephrine in the blood of arteriosclerosis rabbit models and the cardiac function]. | 2003 | Hunan Yi Ke Da Xue Xue Bao | pmid:12934393 |
| Castellani S et al. | Thromboxane inhibition improves renal perfusion and excretory function in severe congestive heart failure. | 2003 | J. Am. Coll. Cardiol. | pmid:12849673 |
| Pettus BJ et al. | Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release. | 2003 | J. Biol. Chem. | pmid:12855693 |
| Shimada N et al. | Increased endothelin: nitric oxide ratio is associated with erythropoietin-induced hypertension in hemodialysis patients. | 2003 | Ren Fail | pmid:12911161 |
| Yi H et al. | [Protective effect of selective cyclooxygenase-2 inhibitor on alcohol-induced liver injury in rats]. | 2003 | Zhonghua Gan Zang Bing Za Zhi | pmid:14636441 |
| Patrono C | Aspirin resistance: definition, mechanisms and clinical read-outs. | 2003 | J. Thromb. Haemost. | pmid:12911581 |
| Villalobos MA et al. | Effects of camonagrel, a selective inhibitor of platelet thromboxane synthase, on the platelet-subendothelium interaction. | 2003 | Pharmacology | pmid:12886030 |
| Miceli M et al. | Effect of low doses of ethanol on platelet function in long-life abstainers and moderate-wine drinkers. | 2003 | Life Sci. | pmid:12865095 |
| Kankuri E et al. | Effects of phenacetin and its metabolite p-phenetidine on COX-1 and COX-2 activities and expression in vitro. | 2003 | Thromb. Res. | pmid:14592552 |
| Heller AR et al. | Clusterin protects the lung from leukocyte-induced injury. | 2003 | Shock | pmid:12865662 |
| Zhang C et al. | Inflammation is involved in the organ damage induced by sinoaortic denervation in rats. | 2003 | J. Hypertens. | pmid:14597858 |
| Wang ZF et al. | The role of inflammatory mediators in severe acute pancreatitis and regulation of glucocorticoids. | 2003 | HBPD INT | pmid:14599960 |
| Eder K et al. | Conjugated linoleic acids lower the release of eicosanoids and nitric oxide from human aortic endothelial cells. | 2003 | J. Nutr. | pmid:14652352 |
| Ziser A et al. | Propofol does not induce pulmonary dysfunction in stressed endotoxic pigs receiving Intralipid. | 2003 | Crit. Care Med. | pmid:12847400 |
| Li JS et al. | [Change in intestinal free radical and prostaglandin metabolism in the aged rats with pneumococcus pneumonia]. | 2003 | Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | pmid:14552688 |
| Sánchez-Muniz FJ et al. | Platelet aggregation, thromboxane production and thrombogenic ratio in postmenopausal women consuming high oleic acid-sunflower oil or palmolein. | 2003 | Eur J Nutr | pmid:14673602 |
| Chen Z et al. | [Correlation between TXB2, 6-Keto-PGF1alpha and liver metastasis in rats model with blood stasis]. | 2003 | Zhong Xi Yi Jie He Xue Bao | pmid:15339561 |
| He LQ et al. | [Effect and mechanism of Tangshenning Recipe on micro-albuminuria in rats with early diabetic nephropathy]. | 2003 | Zhong Xi Yi Jie He Xue Bao | pmid:15339583 |
| Al-Waili NS and Boni NS | Natural honey lowers plasma prostaglandin concentrations in normal individuals. | 2003 | J Med Food | pmid:12935324 |
| Gu L et al. | [Advances in the study on molecular mechanism of diabetic nephropathy treated with Rheum officinale]. | 2003 | Zhongguo Zhong Yao Za Zhi | pmid:15224660 |
| Jones AE et al. | Inhibition of prostaglandin synthesis during polystyrene microsphere-induced pulmonary embolism in the rat. | 2003 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:12639842 |
| De Cristofaro R et al. | Lipid and protein oxidation contribute to a prothrombotic state in patients with type 2 diabetes mellitus. | 2003 | J. Thromb. Haemost. | pmid:12871497 |
| Davì G et al. | Enhanced lipid peroxidation and platelet activation in the early phase of type 1 diabetes mellitus: role of interleukin-6 and disease duration. | 2003 | Circulation | pmid:12810609 |
| Al-Madaney MM et al. | Effects of lipid-esterified conjugated linoleic acid isomers on platelet function: evidence for stimulation of platelet phospholipase activity. | 2003 | Biochim. Biophys. Acta | pmid:14729070 |
| Fujii S et al. | L-arginine reverses p47phox and gp91phox expression induced by high salt in Dahl rats. | 2003 | Hypertension | pmid:14504257 |
| Dong WG et al. | Ameliorative effects of sodium ferulate on experimental colitis and their mechanisms in rats. | 2003 | World J. Gastroenterol. | pmid:14606091 |
| De La Cruz JP et al. | Differences in the effects of extended-release aspirin and plain-formulated aspirin on prostanoids and nitric oxide in healthy volunteers. | 2003 | Fundam Clin Pharmacol | pmid:12803576 |
| Guyton K et al. | Peroxisome proliferator-activated receptor-gamma agonists modulate macrophage activation by gram-negative and gram-positive bacterial stimuli. | 2003 | Shock | pmid:12813370 |
| Montuschi P et al. | Exhaled leukotrienes and prostaglandins in COPD. | 2003 | Thorax | pmid:12832671 |
| Wolfram RM et al. | Narghile (water pipe) smoking influences platelet function and (iso-)eicosanoids. | 2003 | Life Sci. | pmid:14575812 |
| Stephenson AH et al. | Differential effects of 5,6-EET on segmental pulmonary vasoactivity in the rabbit. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12609822 |
| Beck-Speier I et al. | Sulfur-related air pollutants induce the generation of platelet-activating factor, 5-lipoxygenase- and cyclooxygenase-products in canine alveolar macrophages via activation of phospholipases A2. | 2003 | Prostaglandins Other Lipid Mediat. | pmid:14518563 |
| Seebacher F and Franklin CE | Prostaglandins are important in thermoregulation of a reptile (Pogona vitticeps). | 2003 | Proc. Biol. Sci. | pmid:12952634 |
| Cipollone F et al. | Modulation of aspirin-insensitive eicosanoid biosynthesis by 6-methylprednisolone in unstable angina. | 2003 | Circulation | pmid:12515743 |
| Li D et al. | Diet rich in saturated fat decreases the ratio of thromboxane/prostacyclin in healthy men. | 2003 | Biomed. Environ. Sci. | pmid:15011964 |
| Huang RJ et al. | [Effect of tetramethylpyrazine on endothelin, von Willebrand factor and thromboxane A2 during cardiopulmonary bypass in patients of congenital heart disease with pulmonary hypertension]. | 2003 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:12764908 |
| Li ZG et al. | [Progress on study of experimental physico-chemical indexes related with ischemic stroke]. | 2003 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:12764922 |
| Lei D et al. | Antioxidative and antiplatelet effects of aqueous inflorescence Piper betle extract. | 2003 | J. Agric. Food Chem. | pmid:12643677 |
| Park WH et al. | The antiplatelet activity of Geiji-Bokryung-Hwan, Korean traditional formulation, is mediated through inhibition of phospholipase C and inhibition of TxB(2) synthetase activity. | 2003 | Int. Immunopharmacol. | pmid:12810354 |
| Tsipas G and Morphake P | Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity. | 2003 | J. Nutr. Biochem. | pmid:14629893 |
| Hou X et al. | Increased platelet-activating factor-induced periventricular brain microvascular constriction associated with immaturity. | 2003 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:12626359 |
| Tsuruta LR et al. | Characterization of 11-dehydro-thromboxane B2 recombinant antibody obtained by phage display technology. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12628223 |
| Meune C et al. | Aspirin alters arterial function in patients with chronic heart failure treated with ACE inhibitors: a dose-mediated deleterious effect. | 2003 | Eur. J. Heart Fail. | pmid:12798824 |
| Sartin JL et al. | Estradiol plus progesterone treatment modulates select elements of the proinflammatory cytokine cascade in steers: attenuated nitric oxide and thromboxane B2 production in endotoxemia. | 2003 | J. Anim. Sci. | pmid:12817503 |
| Ojanen R et al. | Single dose of acetylsalicylic acid prevents thromboxane release after tourniquet ischemia. | 2003 | J Trauma | pmid:12777914 |
| Dionne RA et al. | Dexamethasone suppresses peripheral prostanoid levels without analgesia in a clinical model of acute inflammation. | 2003 | J. Oral Maxillofac. Surg. | pmid:12966473 |
| Tsipas G and Morphake P | Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity. | 2003 | J. Nutr. Biochem. | pmid:12948879 |
| Cerletti C et al. | Pharmacokinetic and pharmacodynamic differences between two low dosages of aspirin may affect therapeutic outcomes. | 2003 | Clin Pharmacokinet | pmid:12959636 |
| Dai H et al. | Effects of diltiazem on platelet activation and cytosolic calcium during percutaneous transluminal coronary angioplasty. | 2003 | Postgrad Med J | pmid:13679549 |
| Liu H et al. | Clinical implication of the changes of cAMP, TXA2 and PGI2 in CSF of asphyxiated newborns. | 2003 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:12973949 |