Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Acute Kidney Injury D058186 34 associated lipids
Airway Remodeling D056151 3 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Atherosclerosis D050197 85 associated lipids
Dyslipidemias D050171 7 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Coronary Stenosis D023921 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Basta M et al. F(ab)'2-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins. 2003 Nat. Med. pmid:12612546
Fiorucci S et al. Gastrointestinal safety of NO-aspirin (NCX-4016) in healthy human volunteers: a proof of concept endoscopic study. 2003 Gastroenterology pmid:12612897
Vigorita MG et al. Chiral 3,3'-(1,2-ethanediyl)-bis[2-(3,4-dimethoxyphenyl)-4-thiazolidinones] with anti-inflammatory activity. Part 11: evaluation of COX-2 selectivity and modelling. 2003 Bioorg. Med. Chem. pmid:12614885
Vass G et al. Comparison of nasal and oral inhalation during exhaled breath condensate collection. 2003 Am. J. Respir. Crit. Care Med. pmid:12493648
Gama de Abreu M et al. One-lung ventilation with high tidal volumes and zero positive end-expiratory pressure is injurious in the isolated rabbit lung model. 2003 Anesth. Analg. pmid:12505956
Szebeni J et al. Complement activation during hemorrhagic shock and resuscitation in swine. 2003 Shock pmid:14501949
Vani G et al. Histone H1 modulates immune status in experimental breast cancer. 2003 Chemotherapy pmid:14504437
Xia Z et al. Antioxidant therapy with Salvia miltiorrhiza decreases plasma endothelin-1 and thromboxane B2 after cardiopulmonary bypass in patients with congenital heart disease. 2003 J. Thorac. Cardiovasc. Surg. pmid:14666012
Rossoni G et al. Nitric oxide-releasing aspirin inhibits vasoconstriction in perfused tail artery of normotensive and spontaneously hypertensive rats. 2003 Eur. J. Pharmacol. pmid:14512099
Yokoyama Y et al. Role of thromboxane in producing portal hypertension following trauma-hemorrhage. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:14613921
Chen Z et al. [Correlation between TXB2, 6-Keto-PGF1alpha and liver metastasis in rats model with blood stasis]. 2003 Zhong Xi Yi Jie He Xue Bao pmid:15339561
He LQ et al. [Effect and mechanism of Tangshenning Recipe on micro-albuminuria in rats with early diabetic nephropathy]. 2003 Zhong Xi Yi Jie He Xue Bao pmid:15339583
Sheu JR et al. Inhibitory mechanisms of metallothionein on platelet aggregation in in vitro and platelet plug formation in in vivo experiments. 2003 Exp. Biol. Med. (Maywood) pmid:14681547
Fike CD et al. Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigs. 2003 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:12388340
Yokoyama Y et al. Role of thromboxane A2 in early BDL-induced portal hypertension. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12431905
Li D et al. Diet rich in saturated fat decreases the ratio of thromboxane/prostacyclin in healthy men. 2003 Biomed. Environ. Sci. pmid:15011964
Tsipas G and Morphake P Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity. 2003 J. Nutr. Biochem. pmid:12948879
Cerletti C et al. Pharmacokinetic and pharmacodynamic differences between two low dosages of aspirin may affect therapeutic outcomes. 2003 Clin Pharmacokinet pmid:12959636
Dai H et al. Effects of diltiazem on platelet activation and cytosolic calcium during percutaneous transluminal coronary angioplasty. 2003 Postgrad Med J pmid:13679549
Liu H et al. Clinical implication of the changes of cAMP, TXA2 and PGI2 in CSF of asphyxiated newborns. 2003 J. Huazhong Univ. Sci. Technol. Med. Sci. pmid:12973949
Hart RG et al. Aspirin dosage and thromboxane synthesis in patients with vascular disease. 2003 Pharmacotherapy pmid:12741431
Pfeiffer S et al. Hyperacute lung rejection in the pig-to-human model. III. Platelet receptor inhibitors synergistically modulate complement activation and lung injury. 2003 Transplantation pmid:12698079
Arifah AK et al. Pharmacodynamics, chiral pharmacokinetics and PK-PD modelling of ketoprofen in the goat. 2003 J. Vet. Pharmacol. Ther. pmid:12667184
Ji Y et al. Thrombosis and its significance after experimental pulmonary thromboembolism. 2003 Chin. Med. J. pmid:12667387
Davì G et al. Platelet activation in obese women: role of inflammation and oxidant stress. 2002 Oct 23-30 JAMA pmid:12387653
Hayashi M et al. Characterization of five marker levels of the hemostatic system and endothelial status in normotensive pregnancy and pre-eclampsia. 2002 Nov-Dec Eur. J. Haematol. pmid:12460234
Wolfram RM et al. Effect of black tea on (iso-)prostaglandins and platelet aggregation in healthy volunteers. 2002 May-Jun Prostaglandins Leukot. Essent. Fatty Acids pmid:12144875
Alarayyed NA et al. Differential actions of naftopidil, doxazosin and nifedipine on platelet thromboxane generation and platelet-derived growth factor efflux in vitro. 2002 Aug-Sep Platelets pmid:12189011
Sheu JR et al. Mechanisms involved in the antiplatelet activity of magnesium in human platelets. 2002 Br. J. Haematol. pmid:12472585
Fiorucci S et al. NCX-4016 (NO-aspirin) inhibits lipopolysaccharide-induced tissue factor expression in vivo: role of nitric oxide. 2002 Circulation pmid:12473561
Rouvier J et al. Aspirin resistance. 2002 Circulation pmid:12473569
Celik I et al. Effects of ibuprofen on the physiology and outcome of rabbit endotoxic shock. 2002 BMC Infect. Dis. pmid:12445332
Dai CF et al. [Clinical and experimental study of treatment of nanmiqing capsule for chronic prostatitis]. 2002 Zhonghua Nan Ke Xue pmid:12479132
Canbaz M et al. Effects of tibolone on thromboxane B(2) levels in postmenopausal women. 2002 Gynecol. Obstet. Invest. pmid:11803222
Huang F et al. Anti-platelet and anti-thrombotic effects of triacetylshikimic acid in rats. 2002 J. Cardiovasc. Pharmacol. pmid:11791012
Bayorh MA et al. 1A-779 attenuates angiotensin-(1-7) depressor response in salt-induced hypertensive rats. 2002 Peptides pmid:11814618
Kiemer AK et al. Inhibition of cyclooxygenase-2 by natriuretic peptides. 2002 Endocrinology pmid:11861506
Huang K et al. Role of selenium in cytoprotection against cholesterol oxide-induced vascular damage in rats. 2002 Atherosclerosis pmid:11947907
Hu X et al. [The influence of nasal continual positive airway pressure on some vasoactive substances in patients with obstructive sleep apnea syndrome]. 2002 Zhonghua Jie He He Hu Xi Za Zhi pmid:11953098
Burleigh ME et al. Cyclooxygenase-2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice. 2002 Circulation pmid:11956125
Giardiello FM et al. Primary chemoprevention of familial adenomatous polyposis with sulindac. 2002 N. Engl. J. Med. pmid:11932472
Yamasaki M et al. No involvement of interleukin-5 or eosinophils in experimental allergic rhinitis in guinea pigs. 2002 Eur. J. Pharmacol. pmid:11937106
Wilner KD et al. Celecoxib does not affect the antiplatelet activity of aspirin in healthy volunteers. 2002 J Clin Pharmacol pmid:12211219
Molina V et al. D-003, a potential antithrombotic compound isolated from sugar cane wax with effects on arachidonic acid metabolites. 2002 Prostaglandins Leukot. Essent. Fatty Acids pmid:12213431
Koizumi T et al. Inhibition of endogenous nitric oxide during endotoxemia in awake sheep - effects of Nomega-nitro-l-arginine on the distribution of pulmonary vascular resistance and prostanoid products. 2002 Exp. Lung Res. pmid:12217213
Khan I et al. Altered expression of Na(+)/H(+) exchanger isoforms 1 and 3 in clipped and unclipped kidneys of a 2-kidney-1-clip Goldblatt model of hypertension. 2002 Nephron pmid:12218313
Yokoyama C et al. Prostacyclin-deficient mice develop ischemic renal disorders, including nephrosclerosis and renal infarction. 2002 Circulation pmid:12403673
Evgenov OV et al. Methylene blue reduces pulmonary oedema and cyclo-oxygenase products in endotoxaemic sheep. 2002 Eur. Respir. J. pmid:12412689
Bergh K et al. Production of prostaglandin e(2) by iridial melanocytes exposed to latanoprost acid, a prostaglandin F(2 alpha) analogue. 2002 J Ocul Pharmacol Ther pmid:12419090
Chen TL et al. [Effects of fast decompression on prostaglandins content in cerebral tissue of guinea pigs]. 2002 Space Med Med Eng (Beijing) pmid:12222577