Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Acute Kidney Injury D058186 34 associated lipids
Airway Remodeling D056151 3 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Hypoalphalipoproteinemias D052456 5 associated lipids
Atherosclerosis D050197 85 associated lipids
Dyslipidemias D050171 7 associated lipids
Cholecystitis, Acute D041881 1 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Coronary Stenosis D023921 6 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Berrougui H et al. Argan (Argania spinosa) oil lowers blood pressure and improves endothelial dysfunction in spontaneously hypertensive rats. 2004 Br. J. Nutr. pmid:15613254
Restori G et al. Effects of heparan-sulphate administration on clotting parameters and serum thromboxane B2 levels in cholesterol fed rabbits. 1992 Recenti Prog Med pmid:1561475
Macconi D et al. Defective platelet aggregation in response to platelet-activating factor in uremia associated with low platelet thromboxane A2 generation. 1992 Am. J. Kidney Dis. pmid:1562019
Fan JG et al. [Dynamic changes of plasma levels of prostacycline and thromboxane A2 and their correlation with the severity of hepatic injury in rats with nonalcoholic fatty liver disease]. 2004 Zhonghua Gan Zang Bing Za Zhi pmid:15623379
Sciulli MG et al. Platelet activation in patients with colorectal cancer. 2005 Prostaglandins Leukot. Essent. Fatty Acids pmid:15626589
Liu P et al. [Effects of the extracts from decoction for resuscitation and its component herbs on PGI2, TXA2 and NO release from rat vascular endothelial cells under hypoxia in vitro]. 2004 Zhongguo Zhong Yao Za Zhi pmid:15631091
Ohnishi A et al. Effects of a sustained thromboxane synthase inhibition on exercise-induced changes in eicosanoid formation, catecholamine concentration, and platelet aggregation in humans. 1992 Clin. Pharmacol. Ther. pmid:1563215
Yang JP et al. [Changes of the platelet function and serum anticardiolipin antibody in patients with pulmonary thromboembolism]. 2004 Zhonghua Jie He He Hu Xi Za Zhi pmid:15634381
Wang MS et al. [The effects of lupus anticoagulant on pulmonary thromboembolism]. 2004 Zhonghua Jie He He Hu Xi Za Zhi pmid:15634384
Watanabe H et al. Effects of salt loading on blood pressure in mice lacking the prostanoid receptor gene. 2005 Circ. J. pmid:15635218
Vähä-Eskeli K et al. Responses of placental steroids, prostacyclin and thromboxane A2 to thermal stress during pregnancy. 1992 Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:1563566
Spinarová L et al. [Physical training in patients with chornic heart failure: haemodynamics, effects]. 2001 Vnitr Lek pmid:15635849
Franz KB A functional biological marker is needed for diagnosing magnesium deficiency. 2004 J Am Coll Nutr pmid:15637224
Mihai K et al. Balance of prostacyclin and thromboxane in offspring of parents with premature coronary arterial disease. 1992 Int. J. Cardiol. pmid:1563873
Maruyama T et al. Thromboxane-dependent portopulmonary hypertension. 2005 Am. J. Med. pmid:15639216
Esser R et al. Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2. 2005 Br. J. Pharmacol. pmid:15655513
Saumweber DM et al. Studies on xenograft rejection: the role of leukocytes and prostaglandins and their modulation by the hetrazepine WEB 2086BS. 1992 Transplant. Proc. pmid:1566436
Chan CP et al. Inhibition of cyclooxygenase activity, platelet aggregation and thromboxane B2 production by two environmental toxicants: m- and o-cresol. 2005 Toxicology pmid:15664436
Pratschke J et al. Allogeneic heart transplantation following xenografting. 1992 Transplant. Proc. pmid:1566482
Park WH et al. Anti-inflammatory effects of a traditional Korean herbal formulation, Silsosangami, consisting of seven medicinal herbs: effect on hemolysis, neutrophil function, and gene expressions of iNOS and COX-2. 2004 Vascul. Pharmacol. pmid:15664882
Massicot F et al. In vitro assessment of renal toxicity and inflammatory events of two protein phosphatase inhibitors cantharidin and nor-cantharidin. 2005 Basic Clin. Pharmacol. Toxicol. pmid:15667592
Lee GY et al. Antiplatelet activity of BRX-018, (6aS,cis)-malonic acid 3-acetoxy-6a9-bis-(2-methoxycarbonyl-acetoxy)-6,6a,7,11b-tetrahydro-indeno[2,1-c]chromen-10-yl ester methylester. 2005 Thromb. Res. pmid:15668191
Kawamoto M et al. Acute pulmonary edema after intravenous liquid halothane in dogs. 1992 Anesth. Analg. pmid:1567044
Murphy CT and Westwick J Selective inhibition of protein kinase C. Effect on platelet-activating-factor-induced platelet functional responses. 1992 Biochem. J. pmid:1567363
Ye T et al. [Insulin resistance and effects of intravenous acute saline load on renal production of prostaglandin I2 and thromboxane A2 in salt-sensitive hypertensive patients]. 2005 Di Yi Jun Yi Da Xue Xue Bao pmid:15684012
He J et al. Treatment of unstable angina pectoris with modified nuan gan jian--a report of 33 cases. 2004 J Tradit Chin Med pmid:15688691
Arruzazabala ML et al. Effects of d-003, a new substance purified from sugar cane wax, on platelet aggregation and plasma levels of arachidonic acid metabolites in healthy volunteers. 2004 Int J Clin Pharmacol Res pmid:15689052
Sullivan JC et al. Sexual dimorphism in renal production of prostanoids in spontaneously hypertensive rats. 2005 Hypertension pmid:15699443
Masferrer JL et al. Endogenous glucocorticoids regulate an inducible cyclooxygenase enzyme. 1992 Proc. Natl. Acad. Sci. U.S.A. pmid:1570314
Walenga JM et al. Hemostatic abnormalities in total artificial heart patients as detected by specific blood markers. 1992 Ann. Thorac. Surg. pmid:1570981
Arakawa K et al. Bradykinin B2 receptor antagonist FR173657 ameliorates small bowel ischemia-reperfusion injury in dogs. 2005 Dig. Dis. Sci. pmid:15712633
Walshaw PE et al. Diuretic and non-diuretic actions of furosemide: effects of probenecid. 1992 Clin Invest Med pmid:1572111
Trebino CE et al. Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages. 2005 J. Biol. Chem. pmid:15722356
Persico N et al. Transdermal hormone replacement therapy and Doppler findings in normal and overweight postmenopausal patients. 2004 Gynecol. Endocrinol. pmid:15726916
Gama de Abreu M et al. Vaporized perfluorohexane attenuates ventilator-induced lung injury in isolated, perfused rabbit lungs. 2005 Anesthesiology pmid:15731599
Saloheimo P et al. Thromboxane and prostacyclin biosynthesis in patients with acute spontaneous intracerebral hemorrhage. 2005 Thromb. Res. pmid:15733969
Lappegård KT et al. Differential effect of heparin coating and complement inhibition on artificial surface-induced eicosanoid production. 2005 Ann. Thorac. Surg. pmid:15734405
Fimognari FL et al. Nocturnal rise of urinary thromboxane B 2 in patients with coronary artery disease. 2005 Thromb. Haemost. pmid:15735822
Mayer AM et al. Differential modulation of microglia superoxide anion and thromboxane B2 generation by the marine manzamines. 2005 BMC Pharmacol. pmid:15762999
Kalaitzis C et al. Effects of renal denervation of the contralateral kidney on blood pressure and sodium and eicosanoid excretion in the chronic phase of two-kidney, one-clip renovascular hypertension in rats. 2005 Scand. J. Urol. Nephrol. pmid:15764265
Oliveira RL et al. Postmenopausal hormone replacement therapy increases plasmatic thromboxane beta 2. 2005 Int. J. Cardiol. pmid:15771927
García-Saura MF et al. Effects of chronic quercetin treatment in experimental renovascular hypertension. 2005 Mol. Cell. Biochem. pmid:15792364
Léger CL et al. A thromboxane effect of a hydroxytyrosol-rich olive oil wastewater extract in patients with uncomplicated type I diabetes. 2005 Eur J Clin Nutr pmid:15798774
Lukaszyk A et al. Blood platelet function in canine acute pancreatitis with reference to treatment with Nafamostat mesilate (FUT-175). 1992 Thromb. Res. pmid:1579898
Cryer B et al. Double-blind, randomized, parallel, placebo-controlled study of ibuprofen effects on thromboxane B2 concentrations in aspirin-treated healthy adult volunteers. 2005 Clin Ther pmid:15811481
Heard SO et al. Dietary enrichment with omega-3 fatty acids partially protects against lipopolysaccharide-induced atrial depression in rats. 1992 Circ. Shock pmid:1582005
Awad AS et al. Increased renal production of angiotensin II and thromboxane B2 in conscious diabetic rats. 2005 Am. J. Hypertens. pmid:15831366
De Candia E et al. Abnormal pH-sensing of platelet Na+/H+ exchanger in patients with cardiac syndrome X. 2005 Int. J. Cardiol. pmid:15837078
Capone ML et al. Pharmacodynamic interaction of naproxen with low-dose aspirin in healthy subjects. 2005 J. Am. Coll. Cardiol. pmid:15837265
Chang P et al. Therapeutic effects and possible mechanisms of a snake venom preparation in the fibrotic rat liver. 2005 Dig. Dis. Sci. pmid:15844712