Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Uremia D014511 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypoxia D000860 23 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Tuleja E et al. Effects of cyclooxygenases inhibitors on vasoactive prostanoids and thrombin generation at the site of microvascular injury in healthy men. 2003 Arterioscler. Thromb. Vasc. Biol. pmid:12730088
Leese PT et al. The COX-2 selective inhibitor, valdecoxib, does not impair platelet function in the elderly: results of a randomized controlled trial. 2003 J Clin Pharmacol pmid:12751271
Lang I et al. Heterogeneity of microvascular endothelial cells isolated from human term placenta and macrovascular umbilical vein endothelial cells. 2003 Eur. J. Cell Biol. pmid:12751902
Molina V et al. Synergistic effect of D-003 and aspirin on experimental thrombosis models. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12711246
Chavarría ME et al. Prostacyclin/thromboxane early changes in pregnancies that are complicated by preeclampsia. 2003 Am. J. Obstet. Gynecol. pmid:12712098
Dogné JM et al. Pharmacological evaluation of the novel thromboxane modulator BM-567 (I/II). Effects of BM-567 on platelet function. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12538090
De La Cruz P et al. Effects of clopidogrel and ticlopidine on experimental diabetic ischemic retinopathy in rats. 2003 Naunyn Schmiedebergs Arch. Pharmacol. pmid:12595963
Uchida M et al. Changes in cerebral microcirculation during and after abdominal aortic cross-clamping in rabbits: the role of thromboxane A2 receptor. 2003 Anesth. Analg. pmid:12598238
Zaitsu M et al. Thromboxane synthesis is increased by upregulation of cytosolic phospholipase A2 and cyclooxygenase-2 in peripheral polymorphonuclear leukocytes during bacterial infection in childhood. 2003 Am. J. Hematol. pmid:12555215
Kirchheiner J et al. Pharmacokinetics of diclofenac and inhibition of cyclooxygenases 1 and 2: no relationship to the CYP2C9 genetic polymorphism in humans. 2003 Br J Clin Pharmacol pmid:12534640
Cabrera DM et al. A thromboxane A(2) system in the Atlantic stingray, Dasyatis sabina. 2003 Gen. Comp. Endocrinol. pmid:12568793
Ersöz G et al. Effect of sodium selenite treatment on platelet aggregation of streptozotocin-induced diabetic rats. 2003 Thromb. Res. pmid:14698654
Wu X et al. Zileuton, a 5-lipoxygenase inhibitor, increases production of thromboxane A2 and platelet aggregation in patients with asthma. 2003 Am. J. Hematol. pmid:12949886
Vass G et al. Comparison of nasal and oral inhalation during exhaled breath condensate collection. 2003 Am. J. Respir. Crit. Care Med. pmid:12493648
Sidhu P et al. Tissue chamber model of acute inflammation in farm animal species. 2003 Res. Vet. Sci. pmid:12507568
Xia Z et al. Antioxidant therapy with Salvia miltiorrhiza decreases plasma endothelin-1 and thromboxane B2 after cardiopulmonary bypass in patients with congenital heart disease. 2003 J. Thorac. Cardiovasc. Surg. pmid:14666012
Rossoni G et al. Nitric oxide-releasing aspirin inhibits vasoconstriction in perfused tail artery of normotensive and spontaneously hypertensive rats. 2003 Eur. J. Pharmacol. pmid:14512099
Wolfram R et al. Daily prickly pear consumption improves platelet function. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12878452
Yokoyama Y et al. Role of thromboxane in producing portal hypertension following trauma-hemorrhage. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:14613921
Yu CC and Lai YL Chronic hypoxia attenuates ischemia-reperfusion-induced increase in pulmonary vascular resistance. 2003 Life Sci. pmid:12927588
Zhuang HP et al. [Effect of aspirin combined with perindopril on prostacyclin, thromboxone A2, and norepinephrine in the blood of arteriosclerosis rabbit models and the cardiac function]. 2003 Hunan Yi Ke Da Xue Xue Bao pmid:12934393
Castellani S et al. Thromboxane inhibition improves renal perfusion and excretory function in severe congestive heart failure. 2003 J. Am. Coll. Cardiol. pmid:12849673
Pettus BJ et al. Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release. 2003 J. Biol. Chem. pmid:12855693
Shimada N et al. Increased endothelin: nitric oxide ratio is associated with erythropoietin-induced hypertension in hemodialysis patients. 2003 Ren Fail pmid:12911161
Yi H et al. [Protective effect of selective cyclooxygenase-2 inhibitor on alcohol-induced liver injury in rats]. 2003 Zhonghua Gan Zang Bing Za Zhi pmid:14636441
Patrono C Aspirin resistance: definition, mechanisms and clinical read-outs. 2003 J. Thromb. Haemost. pmid:12911581
Villalobos MA et al. Effects of camonagrel, a selective inhibitor of platelet thromboxane synthase, on the platelet-subendothelium interaction. 2003 Pharmacology pmid:12886030
Kankuri E et al. Effects of phenacetin and its metabolite p-phenetidine on COX-1 and COX-2 activities and expression in vitro. 2003 Thromb. Res. pmid:14592552
Zhang C et al. Inflammation is involved in the organ damage induced by sinoaortic denervation in rats. 2003 J. Hypertens. pmid:14597858
Wang ZF et al. The role of inflammatory mediators in severe acute pancreatitis and regulation of glucocorticoids. 2003 HBPD INT pmid:14599960
Eder K et al. Conjugated linoleic acids lower the release of eicosanoids and nitric oxide from human aortic endothelial cells. 2003 J. Nutr. pmid:14652352
Li JS et al. [Change in intestinal free radical and prostaglandin metabolism in the aged rats with pneumococcus pneumonia]. 2003 Zhongguo Wei Zhong Bing Ji Jiu Yi Xue pmid:14552688
Gu L et al. [Advances in the study on molecular mechanism of diabetic nephropathy treated with Rheum officinale]. 2003 Zhongguo Zhong Yao Za Zhi pmid:15224660
Al-Madaney MM et al. Effects of lipid-esterified conjugated linoleic acid isomers on platelet function: evidence for stimulation of platelet phospholipase activity. 2003 Biochim. Biophys. Acta pmid:14729070
Fujii S et al. L-arginine reverses p47phox and gp91phox expression induced by high salt in Dahl rats. 2003 Hypertension pmid:14504257
Bellou A et al. Constitutive nitric oxide synthase inhibition combined with histamine and serotonin receptor blockade improves the initial ovalbumin-induced arterial hypotension but decreases the survival time in brown norway rats anaphylactic shock. 2003 Shock pmid:12558148
De León EJ et al. A new chloroquinolinyl chalcone derivative as inhibitor of inflammatory and immune response in mice and rats. 2003 J. Pharm. Pharmacol. pmid:14604476
Dong WG et al. Ameliorative effects of sodium ferulate on experimental colitis and their mechanisms in rats. 2003 World J. Gastroenterol. pmid:14606091
Halushka MK et al. Genetic variation in cyclooxygenase 1: effects on response to aspirin. 2003 Clin. Pharmacol. Ther. pmid:12545150
Yokoyama Y et al. Role of thromboxane A2 in early BDL-induced portal hypertension. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12431905
Li D et al. Diet rich in saturated fat decreases the ratio of thromboxane/prostacyclin in healthy men. 2003 Biomed. Environ. Sci. pmid:15011964
Huang RJ et al. [Effect of tetramethylpyrazine on endothelin, von Willebrand factor and thromboxane A2 during cardiopulmonary bypass in patients of congenital heart disease with pulmonary hypertension]. 2003 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:12764908
Li ZG et al. [Progress on study of experimental physico-chemical indexes related with ischemic stroke]. 2003 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:12764922
Lei D et al. Antioxidative and antiplatelet effects of aqueous inflorescence Piper betle extract. 2003 J. Agric. Food Chem. pmid:12643677
Park WH et al. The antiplatelet activity of Geiji-Bokryung-Hwan, Korean traditional formulation, is mediated through inhibition of phospholipase C and inhibition of TxB(2) synthetase activity. 2003 Int. Immunopharmacol. pmid:12810354
Hou X et al. Increased platelet-activating factor-induced periventricular brain microvascular constriction associated with immaturity. 2003 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:12626359
Tsuruta LR et al. Characterization of 11-dehydro-thromboxane B2 recombinant antibody obtained by phage display technology. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12628223
Meune C et al. Aspirin alters arterial function in patients with chronic heart failure treated with ACE inhibitors: a dose-mediated deleterious effect. 2003 Eur. J. Heart Fail. pmid:12798824
Arifah AK et al. Pharmacodynamics, chiral pharmacokinetics and PK-PD modelling of ketoprofen in the goat. 2003 J. Vet. Pharmacol. Ther. pmid:12667184
Ji Y et al. Thrombosis and its significance after experimental pulmonary thromboembolism. 2003 Chin. Med. J. pmid:12667387