Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Shimizu T et al. | Up-regulation of Kv7.1 channels in thromboxane A2-induced colonic cancer cell proliferation. | 2014 | Pflugers Arch. | pmid:23995773 |
DeFilippis AP et al. | Fatty acids and TxA(2) generation, in the absence of platelet-COX-1 activity. | 2014 | Nutr Metab Cardiovasc Dis | pmid:24370448 |
Montserrat-de la Paz S et al. | Long-chain fatty alcohols from evening primrose oil inhibit the inflammatory response in murine peritoneal macrophages. | 2014 | J Ethnopharmacol | pmid:24239848 |
Wang Y et al. | DanQi Pill protects against heart failure through the arachidonic acid metabolism pathway by attenuating different cyclooxygenases and leukotrienes B4. | 2014 | BMC Complement Altern Med | pmid:24555740 |
Mayer AM et al. | Vibrio vulnificus MO6-24/O lipopolysaccharide stimulates superoxide anion, thromboxane Bâ‚‚, matrix metalloproteinase-9, cytokine and chemokine release by rat brain microglia in vitro. | 2014 | Mar Drugs | pmid:24675728 |
van den Elsen LW et al. | Dietary fish oil improves endothelial function and lowers blood pressure via suppression of sphingolipid-mediated contractions in spontaneously hypertensive rats. | 2014 | J. Hypertens. | pmid:24569415 |
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Korbecki J et al. | Cyclooxygenase-1 as the main source of proinflammatory factors after sodium orthovanadate treatment. | 2015 | Biol Trace Elem Res | pmid:25398544 |
Al-Husseini A et al. | Increased eicosanoid levels in the Sugen/chronic hypoxia model of severe pulmonary hypertension. | 2015 | PLoS ONE | pmid:25785937 |
Mateu A et al. | Cross-talk between TLR4 and PPARγ pathways in the arachidonic acid-induced inflammatory response in pancreatic acini. | 2015 | Int. J. Biochem. Cell Biol. | pmid:26510582 |
Liu TF et al. | [Correlation between the level of the urinary 11-dehydrothromboxane B2 and the clinical efficacy of aspirin in patients with type 2 diabetes and coronary artery disease]. | 2015 | Beijing Da Xue Xue Bao | pmid:26679651 |
Holland B et al. | Pharmacokinetics and pharmacodynamics of three formulations of firocoxib in healthy horses. | 2015 | J. Vet. Pharmacol. Ther. | pmid:25378135 |
Lüdicke F et al. | A Japanese cross-sectional multicentre study of biomarkers associated with cardiovascular disease in smokers and non-smokers. | 2015 | Biomarkers | pmid:26616146 |
Khanna V et al. | Does the response to aspirin and clopidogrel vary over 6 months in patients with ischemic heart disease? | 2015 | J. Thromb. Haemost. | pmid:25809653 |
Wu F et al. | Valsartan decreases platelet activity and arterial thrombotic events in elderly patients with hypertension. | 2015 | Chin. Med. J. | pmid:25591555 |
Paikin JS et al. | Multiple daily doses of acetyl-salicylic acid (ASA) overcome reduced platelet response to once-daily ASA after coronary artery bypass graft surgery: a pilot randomized controlled trial. | 2015 | J. Thromb. Haemost. | pmid:25546465 |
Bautista-Pérez R et al. | Involvement of neutral sphingomyelinase in the angiotensin II signaling pathway. | 2015 | Am. J. Physiol. Renal Physiol. | pmid:25354938 |
Drew RC et al. | Healthy older humans exhibit augmented carotid-cardiac baroreflex sensitivity with aspirin during muscle mechanoreflex and metaboreflex activation. | 2015 | Am. J. Physiol. Heart Circ. Physiol. | pmid:26371168 |