Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
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Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| O'Sullivan MG et al. | Lipopolysaccharide-induced expression of prostaglandin H synthase-2 in alveolar macrophages is inhibited by dexamethasone but not by aspirin. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8466506 |
| Morris RH and Davies GG | Thin layer chromatographic identification of thromboxane B2 in serum, and platelet rich plasma stimulated by arachidonic acid and collagen. | 1993 | Ann. Clin. Biochem. | pmid:8466155 |
| Wang Y et al. | Pulmonary hypertensive response to rabbit blood components in goats: role of thromboxane. | 1993 | Am. Rev. Respir. Dis. | pmid:8466129 |
| Matera G et al. | Effects of two magainin peptides on eicosanoid release from rat peritoneal macrophages. | 1993 | Antimicrob. Agents Chemother. | pmid:8460910 |
| Chang SW and Ohara N | Increased pulmonary vascular permeability in rats with biliary cirrhosis: role of thromboxane A2. | 1993 | Am. J. Physiol. | pmid:8460713 |
| Olson NC et al. | Pertussis toxin attenuates platelet-activating factor-induced pulmonary hemodynamic alterations in pigs. | 1993 | Am. J. Physiol. | pmid:8460710 |
| Legnani C et al. | Effects of a dried garlic preparation on fibrinolysis and platelet aggregation in healthy subjects. | 1993 | Arzneimittelforschung | pmid:8457236 |
| Moriau M et al. | Platelet anti-aggregant and rheological properties of piracetam. A pharmacodynamic study in normal subjects. | 1993 | Arzneimittelforschung | pmid:8457235 |
| Katusić ZS et al. | Endothelium-dependent contractions to oxygen-derived free radicals in the canine basilar artery. | 1993 | Am. J. Physiol. | pmid:8456988 |
| Sørensen JD et al. | Effects of fish oil supplementation in the third trimester of pregnancy on prostacyclin and thromboxane production. | 1993 | Am. J. Obstet. Gynecol. | pmid:8456902 |
| Canale P et al. | Splanchnic artery occlusion shock: vinblastine-induced leukopenia reduces tumour necrosis factor and thromboxane A2 formation, and increases survival rate. | 1993 Jan-Feb | Pharmacol. Res. | pmid:8456059 |
| Szekeres L and Tósaki A | Release of 6-keto-PGF1 alpha and thromboxane B2 in late appearing cardioprotection induced by the stable PGI analogue: 7-OXO-PGI. | 1993 | Mol. Cell. Biochem. | pmid:8455575 |
| Nyyssönen K et al. | High-performance liquid chromatographic assay of platelet-produced thromboxane B2. | 1993 | J. Chromatogr. | pmid:8454699 |
| Shafique T et al. | Cardiopulmonary bypass and pulmonary thromboxane generation. | 1993 | Ann. Thorac. Surg. | pmid:8452438 |
| Chen HI et al. | Effects of exercise training on the biosynthesis of prostacyclin and thromboxane in rats. | 1993 | Acta Physiol. Scand. | pmid:8452036 |
| Kearon C and Hirsh J | Optimal dose for starting and maintaining low-dose aspirin. | 1993 | Arch. Intern. Med. | pmid:8447706 |
| Del Balzo U et al. | Complement C5a-mediated myocardial ischemia and neutrophil sequestration: two independent phenomena. | 1993 | Am. J. Physiol. | pmid:8447449 |
| Schonwetter DJ et al. | Type A behavior and alcohol consumption: effects on resting and post-exercise bleeding time thromboxane and prostacyclin metabolites. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8446651 |
| Obata T et al. | Inhibitory effect of a peptide leukotriene antagonist ONO-1078 on LTD4- and antigen-induced thromboxane B2 production in guinea pig lungs. | 1993 | Life Sci. | pmid:8445989 |
| Stadler J et al. | Endogenous nitric oxide inhibits the synthesis of cyclooxygenase products and interleukin-6 by rat Kupffer cells. | 1993 | J. Leukoc. Biol. | pmid:8445328 |
| Kontessis PS et al. | Effect of selective inhibition of thromboxane synthesis on renal function in diabetic nephropathy. | 1993 | J. Lab. Clin. Med. | pmid:8445289 |
| Eades SC | Endotoxemia in dairy cattle: role of eicosanoids in reticulorumen stasis. | 1993 | J. Dairy Sci. | pmid:8445095 |
| Hwang DL et al. | Insulin increases intracellular magnesium transport in human platelets. | 1993 | J. Clin. Endocrinol. Metab. | pmid:8445010 |
| Chen TY et al. | Protective effects of anti-O polysaccharide and anti-lipid A monoclonal antibodies on pulmonary hemodynamics. | 1993 | J. Appl. Physiol. | pmid:8444723 |
| Zamora CA et al. | Thromboxane contributes to pulmonary hypertension in ischemia-reperfusion lung injury. | 1993 | J. Appl. Physiol. | pmid:8444695 |
| Westlund P | Purification and some properties of 11-hydroxythromboxane B2 dehydrogenase from porcine kidney. | 1993 | Eur. J. Biochem. | pmid:8444177 |
| Mennander A et al. | Chronic rejection in rat aortic allografts. IV. Effect of hypercholesterolemia in allograft arteriosclerosis. | 1993 Jan-Feb | J. Heart Lung Transplant. | pmid:8443189 |
| Foulon I et al. | Increased in vivo production of thromboxane in patients with sickle cell disease is accompanied by an impairment of platelet functions to the thromboxane A2 agonist U46619. | 1993 | Arterioscler. Thromb. | pmid:8443146 |
| McKinnon KP et al. | In vitro ozone exposure increases release of arachidonic acid products from a human bronchial epithelial cell line. | 1993 | Toxicol. Appl. Pharmacol. | pmid:8442000 |
| Weise WJ et al. | Fish oil has protective and therapeutic effects on proteinuria in passive Heymann nephritis. | 1993 | Kidney Int. | pmid:8441231 |
| Chelucci GL et al. | Aspirin effect on early and late changes in acute lung injury in sheep. | 1993 | Intensive Care Med | pmid:8440792 |
| Häyry P et al. | Role of thromboxane in the generation of allograft arteriosclerosis in chronic rejection. | 1993 | Transplant. Proc. | pmid:8438433 |
| Ogletree ML et al. | Pharmacological profile of BMS 180,291: a potent, long-acting, orally active thromboxane A2/prostaglandin endoperoxide receptor antagonist. | 1993 | J. Pharmacol. Exp. Ther. | pmid:8437108 |
| Hallbrucker C et al. | Hydroperoxide metabolism in rat liver. K+ channel activation, cell volume changes and eicosanoid formation. | 1993 | Eur. J. Biochem. | pmid:8436107 |
| Hansen JB et al. | Effects of cod liver oil on lipids and platelets in males and females. | 1993 | Eur J Clin Nutr | pmid:8436090 |
| Waring P et al. | The effects of leukaemia inhibitory factor on platelet function. | 1993 | Br. J. Haematol. | pmid:8435339 |
| Adatia I et al. | Abnormalities in the biosynthesis of thromboxane A2 and prostacyclin in children with cyanotic congenital heart disease. | 1993 | Br Heart J | pmid:8435245 |
| Cole DJ et al. | Brain eicosanoid levels during temporary focal cerebral ischemia in rats: a microdialysis study. | 1993 | J Neurosurg Anesthesiol | pmid:8431669 |
| Huttemeier PC et al. | Microdialysis measurements of PGD2, TXB2 and 6-KETO-PGF1 alpha in rat CA1 hippocampus during transient cerebral ischemia. | 1993 | Prostaglandins | pmid:8430228 |
| Hata Y et al. | Primary colonic epithelial cell culture of the rabbit producing prostaglandins. | 1993 | Prostaglandins | pmid:8430223 |
| Woods LW et al. | Structural and biochemical changes in lungs of 3-methylindole-treated rats. | 1993 | Am. J. Pathol. | pmid:8424451 |
| Blair IA et al. | Dietary modification of omega 6 fatty acid intake and its effect on urinary eicosanoid excretion. | 1993 | Am. J. Clin. Nutr. | pmid:8424383 |
| Morin CL et al. | Thromboxane production in copper-deficient and marginal platelets: influence of superoxide dismutase and lipid hydroperoxides. | 1993 | Proc. Soc. Exp. Biol. Med. | pmid:8424106 |
| Koudstaal PJ et al. | Increased thromboxane biosynthesis in patients with acute cerebral ischemia. | 1993 | Stroke | pmid:8421822 |
| Van Assche FA et al. | Increased thromboxane formation in diabetic pregnancy as a possible contributor to preeclampsia. | 1993 | Am. J. Obstet. Gynecol. | pmid:8420355 |
| Schiff E et al. | Reduction of thromboxane A2 synthesis in pregnancy by polyunsaturated fatty acid supplements. | 1993 | Am. J. Obstet. Gynecol. | pmid:8420313 |
| Feinberg WM and Bruck DC | Effect of oral nimodipine on platelet function. | 1993 | Stroke | pmid:8418530 |
| Taddei S and Vanhoutte PM | Role of endothelium in endothelin-evoked contractions in the rat aorta. | 1993 | Hypertension | pmid:8418029 |
| Hashimoto K et al. | Perfusion pressure control by adenosine triphosphate given during cardiopulmonary bypass. | 1993 | Ann. Thorac. Surg. | pmid:8417658 |
| Koizumi T et al. | Effects of continuous infusion of nitroglycerin on pulmonary hemodynamics, lung lymph balance, and prostanoid products in the response to endotoxin in awake sheep. | 1993 | Lung | pmid:8416417 |