Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Uremia D014511 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypoxia D000860 23 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Pain D010146 64 associated lipids
Contusions D003288 3 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Pleurisy D010998 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Gastritis D005756 27 associated lipids
Heart Failure D006333 36 associated lipids
Pulmonary Edema D011654 23 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Coronary Disease D003327 70 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypothyroidism D007037 32 associated lipids
Rhinitis D012220 10 associated lipids
Hypercapnia D006935 5 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Pain, Postoperative D010149 13 associated lipids
Asthma D001249 52 associated lipids
Kidney Diseases D007674 29 associated lipids
Femoral Fractures D005264 7 associated lipids
Weight Gain D015430 101 associated lipids
Hyperemia D006940 25 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Acidosis D000138 13 associated lipids
Glioma D005910 112 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Ulcer D014456 16 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Thrombosis D013927 49 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Endometriosis D004715 29 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Myocardial Infarction D009203 21 associated lipids
Proteinuria D011507 30 associated lipids
Arteriosclerosis D001161 86 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Fibrosis D005355 23 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Fetal Diseases D005315 8 associated lipids
Glomerulonephritis D005921 35 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Sepsis D018805 11 associated lipids
Leukopenia D007970 9 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Infarction, Middle Cerebral Artery D020244 35 associated lipids
Stroke D020521 32 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Nephrotic Syndrome D009404 11 associated lipids
Brain Ischemia D002545 89 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Seizures D012640 87 associated lipids
Peptic Ulcer D010437 19 associated lipids
Birth Weight D001724 23 associated lipids
Hypertension D006973 115 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Thromboembolism D013923 6 associated lipids
Nasal Polyps D009298 26 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Tremoli E et al. Platelet thromboxanes and serum-cholesterol. 1979 Lancet pmid:84115
Cole AT et al. In vivo rectal inflammatory mediator changes with radiotherapy to the pelvis. 1993 Gut pmid:8406156
Peng W and Duan SF [Effect of ligustrazine controlled release capsule on hemorrheology in patients with cor pulmonale]. 1993 Zhonghua Nei Ke Za Zhi pmid:8404316
Li JX et al. Age-related differences in responses to endotoxin infusion in unanesthetized piglets. 1993 Circ. Shock pmid:8403245
Fu J et al. [Bioassay of Lyso-PAF platelet activating factor and it's role in bronchial asthma]. 1993 Zhonghua Jie He He Hu Xi Za Zhi pmid:8403058
Lefkos N et al. Hemodynamic and biochemical changes after chronic administration of cilazapril to hypertensive patients. 1993 Cardiology pmid:8402751
Huang YS [Clinical study on main visceral damage and multiple organ failure (MOF) following severe burns]. 1993 Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi pmid:8402345
Somova L and Mufunda J Platelet activity and salt sensitivity in the pathogenesis of systemic (essential) hypertension in black Africans. 1993 Clin. Exp. Hypertens. pmid:8401415
Fu CJ et al. [Effect of ligustrazine on isolated myocardial ischemic reperfusion injury in rats]. 1993 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:8400774
Kramer HJ et al. Effects of thromboxane A2 receptor blockade on oliguric ischemic acute renal failure in conscious rats. 1993 J. Am. Soc. Nephrol. pmid:8400069
Cenni E et al. Numerical and functional modifications in platelets induced by polyester coated by a hydrophilic polymer. 1993 Biomaterials pmid:8399951
Tsikas D et al. Analysis of leukotrienes, prostaglandins, thromboxane B2 and their metabolites by capillary isotachophoresis. 1993 Electrophoresis pmid:8397082
Tönshoff B et al. In vivo prostanoid formation during acute renal allograft rejection. 1993 Nephrol. Dial. Transplant. pmid:8396748
Amari T et al. Effects of recombinant human superoxide dismutase on tumor necrosis factor-induced lung injury in awake sheep. 1993 J. Appl. Physiol. pmid:8396104
Bruni F et al. Synthesis and study of the anti-inflammatory properties of some pyrazolo[1,5-a]pyrimidine derivatives. 1993 J Pharm Sci pmid:8395598
Goldman G et al. Leukocytes mediate acid aspiration-induced multiorgan edema. 1993 Surgery pmid:8395089
Nanji AA et al. Protective effects of a novel quinone derivative, (2E)-3-[5-(2,3 dimethoxy-6-methyl-1,4-benzoquinoyl)]-2-nonyl-2-propanoic acid on experimental alcoholic liver injury. 1993 J. Pharmacol. Exp. Ther. pmid:8394904
Wang ZY et al. Effect of leukotriene B4 on arachidonate metabolism and activation of blood cells and endothelial cells. 1993 Zhongguo Yao Li Xue Bao pmid:8394638
Wang ZY et al. Differential effects of new breviscapine on arachidonic acid metabolisms in blood cells and endothelial cells. 1993 Zhongguo Yao Li Xue Bao pmid:8394637
Chou TZ et al. Effect of felodipine-ER on blood pressure, platelet function, and rheological properties in hypertension. 1993 Can J Cardiol pmid:8394193
Paterson IS et al. Reperfusion plasma contains a neutrophil activator. 1993 Ann Vasc Surg pmid:8390848
Llopis J et al. Eicosanoids released following inhibition of the endoplasmic reticulum Ca2+ pump stimulate Ca2+ efflux in the perfused rat liver. 1993 Biochem. Pharmacol. pmid:8390834
Brightling CE et al. Isoprenaline inhibits thromboxane B2 release from U937 cells. 1993 J. Leukoc. Biol. pmid:8388911
Wiles ME et al. Hypoxia reoxygenation-induced injury of cultured pulmonary microvessel endothelial cells. 1993 J. Leukoc. Biol. pmid:8388909
Farina PR et al. A prodrug of a 2,6-disubstituted 4-(2-arylethenyl)phenol is a selective and orally active 5-lipoxygenase inhibitor. 1993 J. Pharmacol. Exp. Ther. pmid:8388452
Faili A et al. Reduction by arachidonic acid of prostaglandin I2-induced cyclic AMP formation. Involvement of prostaglandins E2 and F2 alpha. 1993 Biochem. Pharmacol. pmid:8388209
Closa D et al. Cyclooxygenase and lipoxygenase metabolism in sodium taurocholate induced acute hemorrhagic pancreatitis in rats. 1993 Prostaglandins pmid:8388115
Kruse-Elliott KT and Olson NC CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs. 1993 Am. J. Physiol. pmid:8386479
Boeynaems JM et al. Enhancement of the endothelial production of prostacyclin by substituted derivatives of BAPTA-AM. 1993 Eur. J. Pharmacol. pmid:8386085
Villanueva M et al. Equipotent inhibition by R(-)-, S(+)- and racemic ibuprofen of human polymorphonuclear cell function in vitro. 1993 Br J Clin Pharmacol pmid:8385973
Oishi K and Yamaguchi M Regulatory effect of arachidonic acid on the calcium transport system in rat liver nuclei. 1993 Biochem. Pharmacol. pmid:8385946
Croft KD and Beilin LJ Platelet and neutrophil function and eicosanoid release in a subject with abetalipoproteinaemia. 1993 Thromb. Res. pmid:8385810
Carrick JB et al. Administration of a receptor antagonist for platelet-activating factor during equine endotoxaemia. 1993 Equine Vet. J. pmid:8385601
Giembycz MA et al. Leukotriene D4 receptors are not negatively coupled to adenylyl cyclase in guinea-pig lung parenchyma. 1993 Br. J. Pharmacol. pmid:8385538
Noronha-Blob L et al. NPC 15669, an inhibitor of neutrophil recruitment, is efficacious in acetic acid-induced colitis in rats. 1993 Gastroenterology pmid:8385041
Gyenes M and De Groot H Prostanoid release by Kupffer cells upon hypoxia-reoxygenation: role of pHi and Cai2+. 1993 Am. J. Physiol. pmid:8384798
Kuratomi Y et al. Effect of a 5-lipoxygenase inhibitor on endotoxin-induced pulmonary dysfunction in awake sheep. 1993 J. Appl. Physiol. pmid:8384614
Smith MA et al. Changes in inflammatory mediators in experimental periodontitis in the rhesus monkey. 1993 Infect. Immun. pmid:8384162
Bruner G and Murphy S Purinergic P2Y receptors on astrocytes are directly coupled to phospholipase A2. 1993 Glia pmid:8384160
Santana AC et al. Anti-inflammatory activities of Ph CL28A in rats in vivo. 1993 Eur. J. Pharmacol. pmid:8384113
Nanji AA et al. Severity of liver injury in experimental alcoholic liver disease. Correlation with plasma endotoxin, prostaglandin E2, leukotriene B4, and thromboxane B2. 1993 Am. J. Pathol. pmid:8382006
Su M et al. Lung mast cells increase in number and degranulate during pulmonary artery occlusion/reperfusion injury in dogs. 1993 Am. Rev. Respir. Dis. pmid:8381632
Jones SA et al. Eicosanoids in third ventricular cerebrospinal fluid of fetal and newborn sheep. 1993 Am. J. Physiol. pmid:8381613
Arora RR et al. Laser-induced stimulation of thromboxane B2 synthesis in human blood platelets: role of superoxide radicals. 1993 Am. Heart J. pmid:8381256
Slama H et al. Metabolism of arachidonic acid by caruncular and allantochorionic tissues in cows with retained fetal membranes (RFM). 1993 Prostaglandins pmid:8380936
Ko FN et al. CIS-19, a novel platelet activating factor receptor antagonist: in vitro and in vivo studies. 1993 Biochim. Biophys. Acta pmid:8380343
Klimm JL et al. Effects of free and macromolecular-bound TXA2 receptor antagonist BM 13.505 on U46619-induced platelet aggregation. 1993 Prostaglandins pmid:8378540
Sullivan MH et al. Effects of a thromboxane synthetase inhibitor on platelet function; possible risks of use in pregnancy. 1993 Prostaglandins pmid:8378539
Chen TY et al. Protective effects of E5, an antiendotoxin monoclonal antibody, in the ovine pulmonary circulation. 1993 J. Appl. Physiol. pmid:8376269
Semrad SD et al. Effect of tirilazad mesylate (U74006F) on eicosanoid and tumor necrosis factor generation in healthy and endotoxemic neonatal calves. 1993 Circ. Shock pmid:8375024