Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kruse-Elliott KT and Olson NC | CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs. | 1993 | Am. J. Physiol. | pmid:8386479 |
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Villanueva M et al. | Equipotent inhibition by R(-)-, S(+)- and racemic ibuprofen of human polymorphonuclear cell function in vitro. | 1993 | Br J Clin Pharmacol | pmid:8385973 |
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Croft KD and Beilin LJ | Platelet and neutrophil function and eicosanoid release in a subject with abetalipoproteinaemia. | 1993 | Thromb. Res. | pmid:8385810 |
Carrick JB et al. | Administration of a receptor antagonist for platelet-activating factor during equine endotoxaemia. | 1993 | Equine Vet. J. | pmid:8385601 |
Giembycz MA et al. | Leukotriene D4 receptors are not negatively coupled to adenylyl cyclase in guinea-pig lung parenchyma. | 1993 | Br. J. Pharmacol. | pmid:8385538 |
Noronha-Blob L et al. | NPC 15669, an inhibitor of neutrophil recruitment, is efficacious in acetic acid-induced colitis in rats. | 1993 | Gastroenterology | pmid:8385041 |
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Su M et al. | Lung mast cells increase in number and degranulate during pulmonary artery occlusion/reperfusion injury in dogs. | 1993 | Am. Rev. Respir. Dis. | pmid:8381632 |
Jones SA et al. | Eicosanoids in third ventricular cerebrospinal fluid of fetal and newborn sheep. | 1993 | Am. J. Physiol. | pmid:8381613 |
Arora RR et al. | Laser-induced stimulation of thromboxane B2 synthesis in human blood platelets: role of superoxide radicals. | 1993 | Am. Heart J. | pmid:8381256 |
Slama H et al. | Metabolism of arachidonic acid by caruncular and allantochorionic tissues in cows with retained fetal membranes (RFM). | 1993 | Prostaglandins | pmid:8380936 |
Ko FN et al. | CIS-19, a novel platelet activating factor receptor antagonist: in vitro and in vivo studies. | 1993 | Biochim. Biophys. Acta | pmid:8380343 |
Klimm JL et al. | Effects of free and macromolecular-bound TXA2 receptor antagonist BM 13.505 on U46619-induced platelet aggregation. | 1993 | Prostaglandins | pmid:8378540 |
Sullivan MH et al. | Effects of a thromboxane synthetase inhibitor on platelet function; possible risks of use in pregnancy. | 1993 | Prostaglandins | pmid:8378539 |
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Semrad SD et al. | Effect of tirilazad mesylate (U74006F) on eicosanoid and tumor necrosis factor generation in healthy and endotoxemic neonatal calves. | 1993 | Circ. Shock | pmid:8375024 |