Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Koshihara Y and Fukuda M | Appearance of metabolic activities for arachidonate during development of mouse embryos. | 1989 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2526512 |
Fuse I and Tai HH | Regulation of arachidonate release by G-proteins and protein kinase C in human platelets. | 1989 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2526540 |
Houtz P and Tai HH | Enzyme immunoassay of thromboxane B2 using immobilized hapten and enzyme amplification. | 1989 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2526560 |
Nowak J and FitzGerald GA | In vivo formation of prostacyclin and thromboxane A2 at the site of platelet-vascular interaction in humans. | 1987 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2959050 |
De Caterina R et al. | Characteristics of thromboxane production by the isolated-perfused rat heart. | 1987 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:2959082 |
Westwick J et al. | Inhibition of thromboxane formation prevents endotoxin-induced renal fibrin deposition in jaundiced rats. | 1983 | Adv. Prostaglandin Thromboxane Leukot. Res. | pmid:6221642 |
Berti F et al. | Immune release of histamine and other lipid mediators from guinea-pig isolated kidney: antagonism by BN-52021. | 1990 | Agents Actions | pmid:1696776 |
Nosál R et al. | Effect of chloroquine on isolated mast cells. | 1991 | Agents Actions | pmid:1716835 |
De Clerck F et al. | Platelet-vessel wall interactions in hemostasis: implication of 5-hydroxytryptamine. | 1984 | Agents Actions | pmid:6543415 |
Ahnfelt-Rønne I et al. | Macrophages from adjuvent arthritic rats preferentially synthetize prostacyclin. | 1980 | Agents Actions | pmid:6992544 |