Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Durando MM et al. | Endotoxin activation of mitogen-activated protein kinase in THP-1 cells; diminished activation following endotoxin desensitization. | 1998 | J. Leukoc. Biol. | pmid:9715266 |
Hsiao G et al. | Antiplatelet action of 3',4'-diisovalerylkhellactone diester purified from Peucedanum japonicum Thunb. | 1998 | Biol. Pharm. Bull. | pmid:9703250 |
Ingster LM and Feinleib M | Salicylate intake and cardiovascular disease: Ingster and Feinleib respond to Hu and Willett. | 1998 | Am J Public Health | pmid:9702172 |
Iida T et al. | The effects of a thromboxane A2 synthesis inhibitor and a prostaglandin I2 analogue on experimental acute necrotizing pancreatitis in rats. | 1998 | Pancreas | pmid:9700944 |
Fagugli RM et al. | Reduction of renal functional reserve in kidney transplant recipients: a possible role of arachidonic acid metabolism alterations. | 1998 | Clin. Nephrol. | pmid:9696430 |
Levy M et al. | Cerebrospinal fluid prostaglandins after systemic dipyrone intake. | 1998 | Clin. Pharmacol. Ther. | pmid:9695726 |
Murphy NP et al. | Functional relevance of the expression of ligand-induced binding sites in the response to platelet GP IIb/IIIa antagonists in vivo. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9694954 |
Ali M et al. | Urothelial synthesis of prostanoids in the ovine ureter. | 1998 | Urol. Res. | pmid:9694598 |
Lebel B et al. | Inhibition of mediator release from dispersed nasal polyp cells by cyclosporin A. | 1998 | Int. Arch. Allergy Immunol. | pmid:9693278 |
Napoli E and Franco N | [Thromboxane A2 production in the pathogenesis of diabetic complications]. | 1998 | Minerva Endocrinol. | pmid:9691631 |
Bell JG et al. | Growth, mortality, tissue histopathology and fatty acid compositions, eicosanoid production and response to stress, in juvenile turbot fed diets rich in gamma-linolenic acid in combination with eicosapentaenoic acid or docosahexaenoic acid. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9690713 |
Stephenson AH et al. | 5,6-Epoxyeicosatrienoic acid reduces increases in pulmonary vascular resistance in the dog. | 1998 | Am. J. Physiol. | pmid:9688901 |
Tewes KS et al. | Measurement of thromboxane B2 in platelet-rich human plasma by gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry following extractive pentafluorobenzyl esterification. | 1998 | Anal. Biochem. | pmid:9683522 |
De La Cruz JP et al. | Effect of camonagrel, a selective thromboxane synthase inhibitor, on retinal vascularization in experimental diabetes. | 1998 | Eur. J. Pharmacol. | pmid:9683018 |
Onizuka M et al. | Suppression of prostanoid formation and regulation of peripheral circulation after surgery using thrombin inhibitor (MD805). | 1998 | Surg. Today | pmid:9681611 |
Cheng Z et al. | Measurement of cyclooxygenase inhibition in vivo: a study of two non-steroidal anti-inflammatory drugs in sheep. | 1998 | Inflammation | pmid:9675607 |
Miyamoto A et al. | The role of thromboxane A2 in regulating porcine basilar arterial tone. | 1998 | J. Vet. Pharmacol. Ther. | pmid:9673964 |
Sheu JR et al. | Inhibitory mechanisms of naloxone on human platelets. | 1998 Jul-Aug | Clin. Exp. Pharmacol. Physiol. | pmid:9673433 |
Kunitoh H et al. | A double-blind, placebo-controlled trial of the thromboxane synthetase blocker OKY-046 on bronchial hypersensitivity in bronchial asthma patients. | 1998 | J Asthma | pmid:9669829 |
Geertsen PF et al. | Renal haemodynamics, sodium and water reabsorption during continuous intravenous infusion of recombinant interleukin-2. | 1998 | Clin. Sci. | pmid:9662488 |