Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Koeberle A et al. | The molecular pharmacology and in vivo activity of 2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid (YS121), a dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase. | 2010 | J. Pharmacol. Exp. Ther. | pmid:19934399 |
| Armstrong PC et al. | Reduction of platelet thromboxane A2 production ex vivo and in vivo by clopidogrel therapy. | 2010 | J. Thromb. Haemost. | pmid:19995405 |
| Carroll RC et al. | Post interventional cardiology urinary thromboxane correlates with PlateletMapping detected aspirin resistance. | 2010 | Thromb. Res. | pmid:19962724 |
| Dragani A et al. | Clinical and laboratory phenotype associated with the aspirin-like defect. | 2010 | Br. J. Haematol. | pmid:19814736 |
| Parmar JH et al. | Significant prostacyclin/thromboxane level imbalance after lower limb arterial angioplasty: a possible platelet function alteration. | 2010 | J Vasc Interv Radiol | pmid:20800778 |
| Kawabata K et al. | Inhibition of secretory phospholipase A2 activity attenuates acute cardiogenic pulmonary edema induced by isoproterenol infusion in mice after myocardial infarction. | 2010 | J. Cardiovasc. Pharmacol. | pmid:20625313 |
| Kim SY et al. | Platelet anti-aggregation activities of compounds from Cinnamomum cassia. | 2010 | J Med Food | pmid:20828311 |
| Bao YM et al. | [Effect of precondition with GBE50 and Salviae miltionrrhizae on cycloxygenase-2 and its downstream effectors contents in ischemia/reperfusion myocardium]. | 2010 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:21066890 |
| De la Cruz JP et al. | Differences in the in vitro antiplatelet effect of dexibuprofen, ibuprofen, and flurbiprofen in human blood. | 2010 | Anesth. Analg. | pmid:21048099 |
| Renda G et al. | Inconsistency of different methods for assessing ex vivo platelet function: relevance for the detection of aspirin resistance. | 2010 | Haematologica | pmid:21123440 |
| Iagoda AV and Gladkikh NN | [Thromboxane-prostacyclin balance and platelet aggregability in patients with minor cardiac abnormalities]. | 2010 | Ter. Arkh. | pmid:21086621 |
| Huang HC et al. | Simvastatin effects on portal-systemic collaterals of portal hypertensive rats. | 2010 | J. Gastroenterol. Hepatol. | pmid:20659230 |
| Ge Y et al. | [Effect of ulinastatin on thromboxane Bâ‚‚ and deep vein thrombosis in elderly patients after hip joint replacement]. | 2010 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:21200097 |
| Antonino MJ et al. | Antiplatelet effects of aspirin with phytosterols: comparison with non-enteric coated aspirin alone. | 2010 | Thromb. Res. | pmid:19446864 |
| Dołegowska B et al. | Dynamics of thromboxane level changes during early phase of allograft reperfusion. | 2009 Sep-Oct | Clin Transplant | pmid:19298388 |
| Tantry US et al. | Aspirin resistance. | 2009 Sep-Oct | Prog Cardiovasc Dis | pmid:19732606 |
| Thomson VS et al. | Aspirin resistance in Indian patients with coronary artery disease and cardiovascular events. | 2009 Oct-Dec | J Postgrad Med | pmid:20083870 |
| Goodman L et al. | Effects of firocoxib and tepoxalin on healing in a canine gastric mucosal injury model. | 2009 Jan-Feb | J. Vet. Intern. Med. | pmid:19175721 |
| Guerrero MD et al. | Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression. | 2009 | Eur. J. Pharmacol. | pmid:19686718 |
| Hu Y et al. | Chinese herbal medicinal ingredients inhibit secretion of IL-6, IL-8, E-selectin and TXB2 in LPS-induced rat intestinal microvascular endothelial cells. | 2009 | Immunopharmacol Immunotoxicol | pmid:19874221 |
| Dietrich-Muszalska A and Olas B | Isoprostenes as indicators of oxidative stress in schizophrenia. | 2009 | World J. Biol. Psychiatry | pmid:19673085 |
| Lowe FJ et al. | Evaluation of biomarkers of exposure and potential harm in smokers, former smokers and never-smokers. | 2009 | Clin. Chem. Lab. Med. | pmid:19676143 |
| Stanke-Labesque F et al. | Increased urinary leukotriene E4 excretion in obstructive sleep apnea: effects of obesity and hypoxia. | 2009 | J. Allergy Clin. Immunol. | pmid:19596146 |
| Huntjens DR et al. | Differences in the sensitivity of behavioural measures of pain to the selectivity of cyclo-oxygenase inhibitors. | 2009 | Eur J Pain | pmid:18774319 |
| Correa JA et al. | Virgin olive oil polyphenol hydroxytyrosol acetate inhibits in vitro platelet aggregation in human whole blood: comparison with hydroxytyrosol and acetylsalicylic acid. | 2009 | Br. J. Nutr. | pmid:18775097 |
| Hynninen VV et al. | Oral voriconazole and miconazole oral gel produce comparable effects on the pharmacokinetics and pharmacodynamics of etoricoxib. | 2009 | Eur. J. Clin. Pharmacol. | pmid:18777173 |
| Muir AR et al. | Assessment of aspirin resistance varies on a temporal basis in patients with ischaemic heart disease. | 2009 | Heart | pmid:18697805 |
| Foudi N et al. | Selective cyclooxygenase-2 inhibition directly increases human vascular reactivity to norepinephrine during acute inflammation. | 2009 | Cardiovasc. Res. | pmid:18952694 |
| Rogers LK et al. | Differential responses in the lungs of newborn mouse pups exposed to 85% or >95% oxygen. | 2009 | Pediatr. Res. | pmid:18703992 |
| Fernández-Arche A et al. | Long-chain fatty alcohols from pomace olive oil modulate the release of proinflammatory mediators. | 2009 | J. Nutr. Biochem. | pmid:18555679 |
| Jespersen B et al. | Differential effects of immunosuppressive drugs on COX-2 activity in vitro and in kidney transplant patients in vivo. | 2009 | Nephrol. Dial. Transplant. | pmid:19193738 |
| Chen SS et al. | Elevated plasma prostaglandins and acetylated histone in monocytes in Type 1 diabetes patients. | 2009 | Diabet. Med. | pmid:19236624 |
| Kanazawa S et al. | Effect of low-dose aspirin for skin rash associated with erlotinib therapy in patients with lung cancer. | 2009 | Platelets | pmid:19172526 |
| Calapai G et al. | Cardiovascular biomarkers in groups of established smokers after a decade of smoking. | 2009 | Basic Clin. Pharmacol. Toxicol. | pmid:19175368 |
| Kapetanovic IM et al. | Comparison of pharmacokinetic and pharmacodynamic profiles of aspirin following oral gavage and diet dosing in rats. | 2009 | Chem. Biol. Interact. | pmid:18992230 |
| Seta F et al. | Renal and cardiovascular characterization of COX-2 knockdown mice. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19357295 |
| Pettinella C et al. | Cyclooxygenase-1 haplotype C50T/A-842G does not affect platelet response to aspirin. | 2009 | Thromb. Haemost. | pmid:19350112 |
| Guagnano MT et al. | Determinants of platelet activation in hypertensives with microalbuminuria. | 2009 | Free Radic. Biol. Med. | pmid:19280705 |
| Lo HM et al. | 2'-Ethoxy-5'-methoxy-2-(5-methylthienyl)chalcone inhibits collagen-induced protein tyrosine phosphorylation and thromboxane formation during platelet aggregation and adhesion. | 2009 | Pharmacology | pmid:19690443 |
| Lauring B et al. | Laropiprant in combination with extended-release niacin does not alter urine 11-dehydrothromboxane B2, a marker of in vivo platelet function, in healthy, hypercholesterolemic, and diabetic subjects. | 2009 | J Clin Pharmacol | pmid:19833861 |
| Eriksson AC et al. | Static platelet adhesion, flow cytometry and serum TXB2 levels for monitoring platelet inhibiting treatment with ASA and clopidogrel in coronary artery disease: a randomised cross-over study. | 2009 | J Transl Med | pmid:19508722 |
| Cattaneo M | Letter by cattaneo regarding article, "incomplete inhibition of thromboxane biosynthesis by acetylsalicylic Acid: determinants and effect on cardiovascular risk". | 2009 | Circulation | pmid:19546394 |
| Schiff M et al. | Platelet inhibitory effects of OTC doses of naproxen sodium compared with prescription dose naproxen sodium and low-dose aspirin. | 2009 | Curr Med Res Opin | pmid:19678751 |
| Cook VL et al. | Effect of firocoxib or flunixin meglumine on recovery of ischemic-injured equine jejunum. | 2009 | Am. J. Vet. Res. | pmid:19645580 |
| Blais N et al. | Response to aspirin in healthy individuals. Cross-comparison of light transmission aggregometry, VerifyNow system, platelet count drop, thromboelastography (TEG) and urinary 11-dehydrothromboxane B(2). | 2009 | Thromb. Haemost. | pmid:19652893 |
| Zhang X et al. | Effect of baicalin on inflammatory mediator levels and microcirculation disturbance in rats with severe acute pancreatitis. | 2009 | Pancreas | pmid:19657312 |
| Liu FC et al. | A new insight of anti-platelet effects of sirtinol in platelets aggregation via cyclic AMP phosphodiesterase. | 2009 | Biochem. Pharmacol. | pmid:19426675 |
| Li L et al. | The anti-inflammatory effects of ZLJ-6, a novel dual cyclooxygenase/5-lipoxygenase inhibitor. | 2009 | Eur. J. Pharmacol. | pmid:19243697 |
| Peng CY et al. | Dietary soy protein selectively reduces renal prostanoids and cyclooxygenases in polycystic kidney disease. | 2009 | Exp. Biol. Med. (Maywood) | pmid:19429858 |
| Li H et al. | [Effect of an integrative medical regimen on levels of vascular endothelial function and hypersensitive C-reactive protein in elderly patients with isolated systolic hypertension]. | 2009 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:19382469 |