Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Edema D004487 152 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Inflammation D007249 119 associated lipids
Hypertension D006973 115 associated lipids
Glioma D005910 112 associated lipids
Weight Gain D015430 101 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Brain Ischemia D002545 89 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Seizures D012640 87 associated lipids
Arteriosclerosis D001161 86 associated lipids
Atherosclerosis D050197 85 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Stomach Ulcer D013276 75 associated lipids
Hyperlipidemias D006949 73 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Coronary Disease D003327 70 associated lipids
Colitis D003092 69 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Reperfusion Injury D015427 65 associated lipids
Pain D010146 64 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Weight Loss D015431 56 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Asthma D001249 52 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Thrombosis D013927 49 associated lipids
Fatty Liver D005234 48 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Hyperalgesia D006930 42 associated lipids
Arthritis D001168 41 associated lipids
Hypotension D007022 41 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Lung Diseases D008171 37 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Heart Failure D006333 36 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Zamecnik J et al. Concentrations of thromboxane B2 and 6-oxo-prostaglandin F1 alpha in amniotic fluid, decidual tissue, and placenta in the later stages of pregnancy in the rat. 1980 Adv Prostaglandin Thromboxane Res pmid:6990719
Frame MH et al. Inhibition of acid secretion from the rat-isolated gastric mucosa by arachidonic acid and identification of major metabolites. 1980 Adv Prostaglandin Thromboxane Res pmid:6990724
Katori M et al. Changes of prostaglandin and thromboxane levels in pleural fluid of rat carrageenin-induced pleurisy. 1980 Adv Prostaglandin Thromboxane Res pmid:7377020
Crutchley DJ et al. Potentiation of thromboxane B2 release from guinea pig lung during anaphylaxis following exposure to 100% O2. 1980 Adv Prostaglandin Thromboxane Res pmid:7377022
Morris HG and Sherman NA Prostaglandin-like substances in urine of asthmatic patients. 1980 Adv Prostaglandin Thromboxane Res pmid:7377024
Schoene NW et al. Effects of diets varying in fat and P/S ratio on arachidonic acid metabolism in human platelets. 1980 Adv Prostaglandin Thromboxane Res pmid:7377026
Güllner HG et al. The principal metabolites of arachidonic acid are overproduced in Bartter's syndrome. 1980 Adv Prostaglandin Thromboxane Res pmid:6892749
Flynn JT and Demling RH Inhibition of endogenous thromboxane synthesis by exogenous prostacyclin during endotoxemia in conscious sheep. 1982 Adv Shock Res pmid:6753534
Lefer AM and Crossley K Mechanisms of the optimal protective effects of ibuprofen in acute myocardial ischemia. 1980 Adv Shock Res pmid:7304314
Hori Y et al. Interaction of endogenous kinins and prostaglandins in the plasma exudation of kaolin-induced pleurisy in rats. 1989 Adv. Exp. Med. Biol. pmid:2481952
Moncada S and Whittle BJ Biological actions of prostacyclin and its pharmacological use in platelet studies. 1985 Adv. Exp. Med. Biol. pmid:3010671
Bourgeois N et al. Effects of endotoxin on hemodynamics of isolated dog kidney. 1987 Adv. Exp. Med. Biol. pmid:3303858
Hadding U et al. Peritoneal macrophages release prostaglandin E and thromboxane B2 in response to C3b. 1982 Adv. Exp. Med. Biol. pmid:7158499
Novo S et al. Platelet activity in relation to smoke and exercise in patients with chronic obstructive lung disease: effects of platelet antiaggregating drugs. 1984 Adv. Exp. Med. Biol. pmid:6546467
Davì G et al. Platelet function changes in acute myocardial infarction. 1984 Adv. Exp. Med. Biol. pmid:6695571
Suchkova V Prostanoid and anti-thrombin III levels in premature infants. 1997 Adv. Exp. Med. Biol. pmid:9547655
Yoshida T et al. Improvement of renal function with selective thromboxane A2 synthetase inhibitor, DP-1904 in lupus nephritis. 1997 Adv. Exp. Med. Biol. pmid:9561116
Müller M In vivo measurement of interstitial TxB2-concentrations in skeletal muscle during ischemia and reperfusion. 1997 Adv. Exp. Med. Biol. pmid:9561122
Arbogast E et al. Intrauterine eicosanoid production in uncomplicated and hypertensive pregnancies: alterations of placental 12-hydroxyeicosatetraenoic acid. 1997 Adv. Exp. Med. Biol. pmid:9561182
Weerasekera DA et al. Chemiluminescence immunoassay of thromboxane B2. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221524