Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Wang SR et al. | [Experimental study on effects of 18 kinds of Chinese herbal medicine for synthesis of thromboxane A2 and PGI2]. | 1993 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:8339039 |
Liu ZQ et al. | [Effect of Astragalus injection on platelet function and plasma endothelin in patients with early stage diabetic nephropathy]. | 2001 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:12577356 |
Lin CL et al. | [Therapeutic mechanism of combination therapy of ligustrazine and nitrendipine in treating patients with chronic obstructive pulmonary disease]. | 2001 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:12577373 |
Tang QZ et al. | [Effect of buyang huanwu decoction on platelet function and fibrinolytic activity of unstable angina pectoris patients]. | 1997 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:10322871 |
Chen SX et al. | [Effects of tetramethylpyrazine on platelet functions of advanced cases of lung carcinoma]. | 1997 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:10322873 |
Xu L et al. | [Clinical and experimental study on effect of Chanbei Kechuanping in treating bronchial asthma]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11789166 |
Han G et al. | [Inhibitory effect of panicoin on platelet activation and its mechanism]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11789213 |
Song WD et al. | [Relationship between local effect of cortisol used by chronic bronchitis patients and syndrome differentiation in TCM]. | 1994 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:7719090 |
Wang XM et al. | [Study on advanced non-small cell lung cancer patients with Qi deficiency and blood stasis syndrome]. | 1994 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:7719106 |
Zhang T et al. | [Clinical observation on preventing and treating coronary atherosclerotic heart disease with tongmai jiangzhi oral liquid]. | 1998 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11367649 |
Wang JW et al. | [Effects of puerarin on the vascular active factor related to cerebral vasospasm after aneurysm subarachnoid hemorrhage]. | 2012 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:22574584 |
Wang CH et al. | [Clinical and experimental study on effect of Chinese herbal drugs on producing prostaglandin in gastric mucosa]. | 1994 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:7865999 |
Wang Z et al. | [Clinical and experimental study on treatment of bronchial asthma with pingchuan oral liquid]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938808 |
Yu K et al. | [Clinical observation on treatment of pediatric intractable nephropathy with modified taohong siwu decoction]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938829 |
Shi X et al. | [Effects of Salvia miltiorrhiza compound injection on serum endothelin, prostaglandin I2/thromboxane A2 ratio alteration following myocardial ischemia-reperfusion in patients undergoing intracardiac surgery]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938858 |
Sun ZT et al. | [Clinical and experimental study on treating bronchial asthma with xingbei granule]. | 1997 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9863090 |
Zhang XY and Qian XM | [Clinical study of sudden deafness treated with method of integrated traditional Chinese and Western medicine]. | 1997 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9863112 |
Wu JX et al. | [Effects and mechanism of emodin and sandostatin on pancreatic ischemia in acute haemorrhagic necrotizing pancreatitis]. | 1997 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9863132 |
Zhu F et al. | [Experimental study on anti-inflammatory and analgesic effects of electroacupuncture combined with medium frequency therapy in model rats with lumbar nerve root compression]. | 2011 | Zhongguo Zhen Jiu | pmid:21894700 |
Zeng HH et al. | [Effect of safflower injection on pulmonary hypertension in rat during chronic hypoxia and hypercapnia]. | 2009 | Zhongguo Ying Yong Sheng Li Xue Za Zhi | pmid:21186611 |
Wang Z et al. | [Na [125I]-labelled 6-keto-PGF1 alpha and thromboxane B2]. | 1986 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:2943448 |
Wang Z | [Radioimmunoassay of thromboxane B2]. | 1986 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:2944644 |
Wang Z et al. | [Preliminary report on the application of thromboxane B2 radioimmunoassay]. | 1986 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:2953485 |
Wang L and Wang Z | [The effects of ilexonin A on AA metabolism]. | 1991 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:1831714 |
Xiao D | [Inhibition of phorbol ester and A23187-stimulated prostaglandins synthesis in macrophages by anisodamine]. | 1990 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:2147587 |
Yu Y et al. | [Changes of prostaglandins in kidney tissue in gentamicin-induced acute renal tubular injury in rats]. | 1998 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:11367732 |
Lin Y and Sun M | [Vasoactive intestinal polypeptide prevents injury of pulmonary vascular permeability due to xanthine with xanthine oxidase]. | 1995 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:8575046 |
Qu C et al. | Effect of fenofibrate on the secretion of endothelium-derived contracting factors in hypertensive rats. | 2012 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:22776656 |
Li H | [The effects of electro-acupuncture on exudate volume and TXB2, 6-keto-PGF1 alpha content in the pleural cavity after carrageenin-induced pleurisy in rats]. | 1987 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:2964932 |
Xu SH | [Preliminary observation on plasma level of 5-HT, TXB2 and 6-keto-PGF1 alpha in TEPH]. | 1988 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:2978253 |
Wang YL et al. | Effect of ubiquinone on ischemic arrhythmia in conscious rats. | 1991 | Zhongguo Yao Li Xue Bao | pmid:1781279 |
Wang Z et al. | [Sodium ferulate is an inhibitor of thromboxane A2 synthetase]. | 1988 | Zhongguo Yao Li Xue Bao | pmid:3218538 |
Fu JM et al. | [Effects of oxyfedrine on platelet thromboxane A2 and aorta prostacyclins formations]. | 1988 | Zhongguo Yao Li Xue Bao | pmid:3218539 |
Rui YC et al. | [Effect of dazoxiben on the metabolism of arachidonic acid in isolated porcine basilar arteries]. | 1990 | Zhongguo Yao Li Xue Bao | pmid:2128432 |
Chu GX and Chen X | Anti-lipid peroxidation and protection of ginsenosides against cerebral ischemia-reperfusion injuries in rats. | 1990 | Zhongguo Yao Li Xue Bao | pmid:2275384 |
Zhang YL et al. | [Protective action of sophoridine on acute myocardial infarction in anesthetized dogs]. | 1991 | Zhongguo Yao Li Xue Bao | pmid:1781291 |
Ren YJ et al. | Inhibitory effects of nimodipine on platelet aggregation and thrombosis. | 1998 | Zhongguo Yao Li Xue Bao | pmid:10374642 |
Shan CW et al. | Inhibitory effects of procainamide on rabbit platelet aggregation and thromboxane B2 production in vitro. | 1998 | Zhongguo Yao Li Xue Bao | pmid:10374644 |
Zhang P et al. | [Effects of methylflavonolamine on TXA2 and PGI2 plasma levels in rabbits with myocardial infarction]. | 1993 | Zhongguo Yao Li Xue Bao | pmid:8237408 |
Du ZY and Huang YH | Effects of tetrandrine on production of leukotriene B4 and thromboxane B2 in rabbit blood. | 1993 | Zhongguo Yao Li Xue Bao | pmid:8249626 |
Shen ZQ et al. | Inhibitory effects of copper-aspirin complex on platelet aggregation. | 1997 | Zhongguo Yao Li Xue Bao | pmid:10072923 |
Zeng S and Guo ZG | Mepyramine inhibits platelet activating factor-induced rabbit platelet aggregation: role of intracellular histamine. | 1997 | Zhongguo Yao Li Xue Bao | pmid:10072970 |
Xiao D et al. | Effects of quercetin on platelet and reperfusion-induced arrhythmias in rats. | 1993 | Zhongguo Yao Li Xue Bao | pmid:8010047 |
Xuan B et al. | Inhibitory effect of tetrahydroberberine on platelet aggregation and thrombosis. | 1994 | Zhongguo Yao Li Xue Bao | pmid:8010106 |
Sun XM et al. | [Effect of 2-naphthyl-3- (3,4-dimethoxy) phenyl-propenoic acid on the metabolism of arachidonic acid in rabbit platelets]. | 1990 | Zhongguo Yao Li Xue Bao | pmid:2403015 |
Rui YC et al. | [Effect of dazoxiben on cerebrovascular resistance in rabbits]. | 1989 | Zhongguo Yao Li Xue Bao | pmid:2624120 |
Wang YZ et al. | Reducing effect of 3,4',5-trihydroxystibene-3-beta-mono-D-glucoside on arterial thrombosis induced by vascular endothelial injury. | 1995 | Zhongguo Yao Li Xue Bao | pmid:7597920 |
Chen XS et al. | Effects of CI-930, a novel phosphodiesterase III inhibitor, on platelet aggregation and arachidonic acid metabolism. | 1990 | Zhongguo Yao Li Xue Bao | pmid:1966575 |
Jiang YY et al. | [Effects of econazole and clotrimazole on TXB2 and PGE2 production in calcimycin-stimulated neutrophils and arachidonic acid-stimulated platelets]. | 1991 | Zhongguo Yao Li Xue Bao | pmid:1781294 |
Huang CG et al. | [Effects of berberine on synthesis of platelet TXA2 and plasma PGI2 in rabbits]. | 1991 | Zhongguo Yao Li Xue Bao | pmid:1824005 |