Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Yue TL and Tong L | [Effects of dauricine on the metabolism of arachidonic acid in rat pleural neutrophils]. | 1989 | Zhongguo Yao Li Xue Bao | pmid:2558500 |
Fang YX et al. | Beneficial changes in prostacyclin and thromboxane A2 induced by ginsenosides in myocardial infarction and reperfusion injury in dogs. | 1986 | Zhongguo Yao Li Xue Bao | pmid:2954367 |
Zhu L et al. | [Effects of sodium beta-3,4-dihydroxyphenyl lactate and beta-phenyl lactic acid on prostacycline and thromboxane A2 contents in the plasma of rabbits after coronary artery occlusion]. | 1986 | Zhongguo Yao Li Xue Bao | pmid:2955643 |
Ren YJ et al. | Inhibitory effects of nimodipine on platelet aggregation and thrombosis. | 1998 | Zhongguo Yao Li Xue Bao | pmid:10374642 |
Shan CW et al. | Inhibitory effects of procainamide on rabbit platelet aggregation and thromboxane B2 production in vitro. | 1998 | Zhongguo Yao Li Xue Bao | pmid:10374644 |
Chen CX et al. | Inhibitory effect of rhynchophylline on platelet aggregation and thrombosis. | 1992 | Zhongguo Yao Li Xue Bao | pmid:1317985 |
Zhang P et al. | [Effects of methylflavonolamine on TXA2 and PGI2 plasma levels in rabbits with myocardial infarction]. | 1993 | Zhongguo Yao Li Xue Bao | pmid:8237408 |
Tan JQ et al. | [Effects of trilobine on platelet aggregation, thromboxane A2, and prostacyclin formation in rats]. | 1991 | Zhongguo Yao Li Xue Bao | pmid:1807088 |
Xiao D et al. | Effects of quercetin on platelet and reperfusion-induced arrhythmias in rats. | 1993 | Zhongguo Yao Li Xue Bao | pmid:8010047 |
Xuan B et al. | Inhibitory effect of tetrahydroberberine on platelet aggregation and thrombosis. | 1994 | Zhongguo Yao Li Xue Bao | pmid:8010106 |
Sun XM et al. | [Effect of 2-naphthyl-3- (3,4-dimethoxy) phenyl-propenoic acid on the metabolism of arachidonic acid in rabbit platelets]. | 1990 | Zhongguo Yao Li Xue Bao | pmid:2403015 |
Wang YZ et al. | Reducing effect of 3,4',5-trihydroxystibene-3-beta-mono-D-glucoside on arterial thrombosis induced by vascular endothelial injury. | 1995 | Zhongguo Yao Li Xue Bao | pmid:7597920 |
Li JS et al. | [Change in intestinal free radical and prostaglandin metabolism in the aged rats with pneumococcus pneumonia]. | 2003 | Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | pmid:14552688 |
Yin M et al. | [Experimental study of effects of cyclooxygenase-2 inhibitor on apoptosis of hypoxic myocardial cells in vitro]. | 2006 | Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | pmid:16647015 |
Sha JP et al. | [Effect of the recombinant staphylokinase on pancreatic ischemia in severe acute pancreatitis of rats]. | 2007 | Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | pmid:17708840 |
Zhang J et al. | [Isolation of resisting thrombus and arteriosclerosis compounds in leaves of Salix matsudana]. | 1999 | Zhong Yao Cai | pmid:12575095 |
Xu L et al. | [Effects of effective component from "qing kai ling" on endothelial cell of microvessel in MCAO rats]. | 2004 | Zhong Yao Cai | pmid:15376390 |
Wei X et al. | [Study of dahuangzhechong pills on anti-arterial thrombosis with the orthogonal design]. | 2012 | Zhong Yao Cai | pmid:22734422 |
Li XQ et al. | [Experimental study on the treatment of hypertension with combined traditional Chinese and Western medicine]. | 1991 | Zhong Xi Yi Jie He Za Zhi | pmid:1725972 |
Wang ZY | [Inhibitory effects of new-breviscapine on thrombosis in vivo]. | 1989 | Zhong Xi Yi Jie He Za Zhi | pmid:2776271 |
Wang S and Zhu G | [Effects of Codonopsis pilosulae on the synthesis of thromboxane A2 and prostacyclin]. | 1990 | Zhong Xi Yi Jie He Za Zhi | pmid:2208415 |
Zhang YZ and Yan XF | [Effects of nifedipine and Paeonia lactiflora on plasma TXB2 and 6-Keto-PGF1 alpha in cholesterol-fed rabbits]. | 1990 | Zhong Xi Yi Jie He Za Zhi | pmid:2268930 |
Yu Z and Chen KJ | [Effect of chuan-xiong granules on platelet aggregation, plasma beta-thromboglobulin, platelet factor IV, thromboxane B2 and 6-keto-prostaglandin F1 alpha in coronary disease patients]. | 1987 | Zhong Xi Yi Jie He Za Zhi | pmid:2954711 |
Bao FZ and Shi G | [Clinical and experimental study on the treatment of angina pectoris with kuo guan granules]. | 1987 | Zhong Xi Yi Jie He Za Zhi | pmid:3690755 |
Liu Z | [Effects of Ligusticum wallichii on the plasma levels of beta-thromboglobulin, platelet factor 4, thromboxane B2 and 6-keto-PGF1 alpha in rabbits under acute experimental cerebral ischemia]. | 1990 | Zhong Xi Yi Jie He Za Zhi | pmid:2148509 |
Wang SR and Liao JZ | [Effects of qixue injections on the function of platelets in coronary disease patients]. | 1987 | Zhong Xi Yi Jie He Za Zhi | pmid:3594704 |
Xu QY and Jia BS | [Relation between plasma thromboxane B2 and 6-keto-prostaglandin F1 alpha levels and traditional Chinese medicine in different types of ischemic heart disease patients]. | 1987 | Zhong Xi Yi Jie He Za Zhi | pmid:3594705 |
Liang XC and Guo SS | [Effect of jiang-zhi zhong-yao-pian on total cholesterol, triglyceride, TXB2, 6-keto-PGF1 alpha in hyperlipemic patients]. | 1991 | Zhong Xi Yi Jie He Za Zhi | pmid:2054886 |
Dong G | [Relation of pale tongue, purple tongue and TXA2-PGI2 regulation system]. | 1990 | Zhong Xi Yi Jie He Za Zhi | pmid:2401034 |
Wang CB and Chang AM | [Plasma thromboxane B2 changes in severe icteric hepatitis treated by traditional Chinese medicine--dispelling the pathogenic heat from blood, promoting blood circulation and administrating large doses of radix Paeoniae--a report of 6 cases]. | 1985 | Zhong Xi Yi Jie He Za Zhi | pmid:3161645 |
Xu XY and Wang Q | [The influence of sodium ferulate on hypotensive effect and urinary excretion of TXB2 after captopril in essential hypertensive patients]. | 1991 | Zhong Xi Yi Jie He Za Zhi | pmid:1667512 |
Liu Z | [Effects of Ligusticum wallichii on the plasma levels of beta-thromboglobulin, platelet factor 4, thromboxane B2 and 6-keto-PGF1 alpha in patients with acute cerebral infarction]. | 1991 | Zhong Xi Yi Jie He Za Zhi | pmid:1840363 |
Huang HF and Wang M | [Effects of gossypol and GnRHa on the prostaglandins contents of endometriotic cell and in situ]. | 1991 | Zhong Xi Yi Jie He Za Zhi | pmid:1773465 |
Xi ZQ | [Clinical application and prospect of bulbus Allii for relieving asthma]. | 1991 | Zhong Xi Yi Jie He Za Zhi | pmid:1773477 |
Yang MF | [Thromboxane B2 (125I) radioimmunoassay and its clinical uses]. | 1988 | Zhong Xi Yi Jie He Za Zhi | pmid:3255548 |
Lin ZX et al. | [Relation between malondialdehyde generation by platelets and plasma thromboxane B2 and diagnostic classification by syndrome differentiation of traditional Chinese medicine in stroke during acute stage]. | 1991 | Zhong Xi Yi Jie He Za Zhi | pmid:1821334 |
Yang G et al. | [Anti-angina effect of puerarin and its effect on plasma thromboxane A2 and prostacyclin]. | 1990 | Zhong Xi Yi Jie He Za Zhi | pmid:2364466 |
Wang C et al. | [Relation of changes in plasma TXB2 PGF1alpha and differentiation of signs and symptoms in traditional Chinese medicine in severe icteric hepatitis]. | 1990 | Zhong Xi Yi Jie He Za Zhi | pmid:2379294 |
Zhao GR et al. | [Clinical study on relationship between sluggishness of lung-defensive qi and levels of vasoactive intestinal polypeptide and thromboxane B2]. | 2004 | Zhong Xi Yi Jie He Xue Bao | pmid:15383251 |
Ming HX et al. | [Influence of single leaf Asarum himalaicum on renal function of rabbits]. | 2004 | Zhong Xi Yi Jie He Xue Bao | pmid:15339444 |
Chen Z et al. | [Correlation between TXB2, 6-Keto-PGF1alpha and liver metastasis in rats model with blood stasis]. | 2003 | Zhong Xi Yi Jie He Xue Bao | pmid:15339561 |
He LQ et al. | [Effect and mechanism of Tangshenning Recipe on micro-albuminuria in rats with early diabetic nephropathy]. | 2003 | Zhong Xi Yi Jie He Xue Bao | pmid:15339583 |
Sun LQ et al. | [Relationship between syndrome differentiation of traditional Chinese medicine and vascular endothelial function in patients with diabetic arterial occlusion of lower extremities]. | 2007 | Zhong Xi Yi Jie He Xue Bao | pmid:17997934 |
Chen C et al. | [Effects of extracts of Radix Scrophulariae on blood pressure in spontaneously hypertensive rats and the underlying mechanisms]. | 2012 | Zhong Xi Yi Jie He Xue Bao | pmid:22979933 |
Ge Y et al. | [Effect of ulinastatin on thromboxane Bâ‚‚ and deep vein thrombosis in elderly patients after hip joint replacement]. | 2010 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:21200097 |
Shi JJ and Huang LF | [Effects of transcutaneous electrical acupoint stimulation of "Zusanli" (ST 36) on gastric mucosal injury in exercise stress-induced gastric ulcer rats]. | 2013 | Zhen Ci Yan Jiu | pmid:24006661 |
Tang Z | [Effect of moxibustion on humoral factors in the rat infected with epidemic hemorrhagic fever virus]. | 1992 | Zhen Ci Yan Jiu | pmid:1364109 |
Tang Z et al. | [Influence of moxibustion on TXA2 and PGI2 in plasma of rat infected epidemic hemorrhagic fever virus (EHFV)]. | 1992 | Zhen Ci Yan Jiu | pmid:1356657 |
Xu N | [Effect of electroacupuncture at "taixi" point on plasma thromboxane A2 and prostacyclin in the rabbit with renal ischemia]. | 1993 | Zhen Ci Yan Jiu | pmid:7923725 |
Liu Z | [Effects of acupuncture on lipid, TXB2, 6-keto-PGF, alpha in simple obese patients complicated with hyperlipidemia]. | 1996 | Zhen Ci Yan Jiu | pmid:9388312 |