Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Aharony D et al. | Regulation of arachidonate-induced platelet aggregation by the lipoxygenase product, 12-hydroperoxyeicosatetraenoic acid. | 1982 | Biochim. Biophys. Acta | pmid:6814496 |
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Tooke JE et al. | Aspirin, prostacyclin and post-occlusive reactive hyperaemia in man. | 1982 | Prostaglandins Leukot Med | pmid:6757966 |
Herman CA et al. | Prostaglandins of the one, two, and three series affect blood pressure in the american bullfrog, Rana catesbeiana. | 1982 | Gen. Comp. Endocrinol. | pmid:6761235 |
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Goldsmith JC and Needleman SW | A comparative study of thromboxane and prostacyclin release from ex vivo and cultured bovine vascular endothelium. | 1982 | Prostaglandins | pmid:6815717 |
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Karmali RA et al. | Prostaglandin regulation of murine mammary tumor virus production: a basis for some of the glucocorticoid and prolactin actions on mammary tumor cell cultures. | 1982 | Prostaglandins Leukot Med | pmid:6296884 |
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Mest HJ et al. | Influence of mental stress on plasma level of prostaglandins, thromboxane B2 and on circulating platelet aggregates in man. | 1982 | Prostaglandins Leukot Med | pmid:6955811 |
Karmali RA et al. | Macrophage production of prostaglandins: effects of fetal calf serum and diazepam. Use of an improved method for extracting 6-keto-PGF1 alpha. | 1982 | Prostaglandins Leukot Med | pmid:6955812 |
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Burch RM and Halushka PV | Vasopressin stimulates prostaglandin and thromboxane synthesis in toad bladder epithelial cells. | 1982 | Am. J. Physiol. | pmid:6816073 |
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Tai HH | Assay of thromboxane A synthase inhibitors. | 1982 | Meth. Enzymol. | pmid:6890139 |
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Robinson C et al. | Thromboxane B2 uptake and metabolism in isolated perfused lung. Identification and comparison with prostaglandin F2 alpha. | 1982 | Biochim. Biophys. Acta | pmid:6751406 |
Schafer AI et al. | Platelet lipoxygenase-dependent oxygen burst. Evidence for differential activation of lipoxygenase in intact and disrupted human platelets. | 1982 | Biochim. Biophys. Acta | pmid:6812645 |
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