Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hamberg M et al. | A method for measurement of platelet regeneration in man. | 1978 | Prostaglandins Med | pmid:104315 |
McCowan LM et al. | Administration of low-dose aspirin to mothers with small for gestational age fetuses and abnormal umbilical Doppler studies to increase birthweight: a randomised double-blind controlled trial. | 1999 | Br J Obstet Gynaecol | pmid:10428519 |
Kawano K et al. | Superiority of platelet integrin GPIIb-IIIa receptor antagonist over aspirin in preventing cyclic flow reductions in the guinea pig middle cerebral artery. | 1999 | Eur. J. Pharmacol. | pmid:10422782 |
Mercer JB et al. | The effect of short-term cold exposure on risk factors for cardiovascular disease. | 1999 | Thromb. Res. | pmid:10418798 |
Morrow JD et al. | Increased formation of thromboxane in vivo in humans with mastocytosis. | 1999 | J. Invest. Dermatol. | pmid:10417625 |
Jönsson A et al. | Effects of amide local anaesthetics on eicosanoid formation in burned skin. | 1999 | Acta Anaesthesiol Scand | pmid:10408815 |
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Peredo HA et al. | Time-course of the alterations in prostanoid production and in contractile responses of mesenteric beds isolated from streptozotocin diabetic rats. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10397409 |
Bowers W et al. | Artificial human skin: cytokine, prostaglandin, Hsp70 and histological responses to heat exposure. | 1999 | J. Dermatol. Sci. | pmid:10397388 |
Maitra SR et al. | Alterations in hepatic gluconeogenesis, prostanoid, and intracellular calcium during sepsis. | 1999 | Acad Emerg Med | pmid:10386675 |
Itasaka H et al. | The mechanism of hepatic graft protection against reperfusion injury by prostaglandin E1. | 1999 | Surg. Today | pmid:10385367 |
Brown N et al. | Comparison of antiplatelet activity of microencapsulated aspirin 162.5 Mg (Caspac XL), with enteric coated aspirin 75 mg and 150 mg in patients with atherosclerosis. | 1999 | Br J Clin Pharmacol | pmid:10383561 |
Williams CA et al. | The flavonoids of Tanacetum parthenium and T. vulgare and their anti-inflammatory properties. | 1999 | Phytochemistry | pmid:10382317 |
Kubo K et al. | A 21-aminosteroid, U-74006F, attenuates endotoxin-induced lung injury in awake sheep. | 1999 | Respirology | pmid:10382236 |
Cryer B and Feldman M | Effects of very low dose daily, long-term aspirin therapy on gastric, duodenal, and rectal prostaglandin levels and on mucosal injury in healthy humans. | 1999 | Gastroenterology | pmid:10381905 |
Freedman JE et al. | Deficient platelet-derived nitric oxide and enhanced hemostasis in mice lacking the NOSIII gene. | 1999 | Circ. Res. | pmid:10381894 |
Panara MR et al. | Dose-dependent inhibition of platelet cyclooxygenase-1 and monocyte cyclooxygenase-2 by meloxicam in healthy subjects. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10381787 |
Walsh SW et al. | AA-2414, an antioxidant and thromboxane receptor blocker, completely inhibits peroxide-induced vasoconstriction in the human placenta. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10381779 |
Tanaka H et al. | Leukotriene (LT)-receptor antagonist is more effective in asthmatic patients with a low baseline ratio of urinary LTE4 to 2,3-dinor-6-keto-prostaglandin (PG)F1alpha. | 1999 | Allergy | pmid:10380781 |