Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Jiang J et al. | Effect of Marine-Derived n-3 Polyunsaturated Fatty Acids on Major Eicosanoids: A Systematic Review and Meta-Analysis from 18 Randomized Controlled Trials. | 2016 | PLoS ONE | pmid:26808318 |
Taneja A et al. | Biomarker exposure-response relationships as the basis for rational dose selection: Lessons from a simulation exercise using a selective COX-2 inhibitor. | 2016 | J Clin Pharmacol | pmid:26331692 |
Siewiera K et al. | Long-term untreated streptozotocin-diabetes leads to increased expression and elevated activity of prostaglandin H2 synthase in blood platelets. | 2016 | Platelets | pmid:26325148 |
Yan H et al. | Seawater Immersion Aggravates Burn Injury Causing Severe Blood Coagulation Dysfunction. | 2016 | Biomed Res Int | pmid:26885523 |
Korbecki J et al. | Cyclooxygenase-1 as the main source of proinflammatory factors after sodium orthovanadate treatment. | 2015 | Biol Trace Elem Res | pmid:25398544 |
Liu TF et al. | [Correlation between the level of the urinary 11-dehydrothromboxane B2 and the clinical efficacy of aspirin in patients with type 2 diabetes and coronary artery disease]. | 2015 | Beijing Da Xue Xue Bao | pmid:26679651 |
Holland B et al. | Pharmacokinetics and pharmacodynamics of three formulations of firocoxib in healthy horses. | 2015 | J. Vet. Pharmacol. Ther. | pmid:25378135 |
Lüdicke F et al. | A Japanese cross-sectional multicentre study of biomarkers associated with cardiovascular disease in smokers and non-smokers. | 2015 | Biomarkers | pmid:26616146 |
Bautista-Pérez R et al. | Involvement of neutral sphingomyelinase in the angiotensin II signaling pathway. | 2015 | Am. J. Physiol. Renal Physiol. | pmid:25354938 |
Drew RC et al. | Healthy older humans exhibit augmented carotid-cardiac baroreflex sensitivity with aspirin during muscle mechanoreflex and metaboreflex activation. | 2015 | Am. J. Physiol. Heart Circ. Physiol. | pmid:26371168 |