Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Uremia D014511 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypoxia D000860 23 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Pain D010146 64 associated lipids
Contusions D003288 3 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Pleurisy D010998 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Gastritis D005756 27 associated lipids
Heart Failure D006333 36 associated lipids
Pulmonary Edema D011654 23 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Coronary Disease D003327 70 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypothyroidism D007037 32 associated lipids
Rhinitis D012220 10 associated lipids
Hypercapnia D006935 5 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Pain, Postoperative D010149 13 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
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Bisordi JE et al. Interaction of vasopressin and prostaglandins in the toad urinary bladder. 1980 J. Clin. Invest. pmid:6777397
Burch RM and Halushka PV Thromboxane and stable prostaglandin endoperoxide analogs stimulate water permeability in the toad urinary bladder. 1980 J. Clin. Invest. pmid:6777398
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Fitzpatrick TM et al. Tromboxane B2 inhibits the pulmonary inactivation of prostaglandin E2 in the dog. 1980 Br. J. Pharmacol. pmid:7000216
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Sanger GJ and Bennett A Trimethoquinol selectively antagonizes contractions of rat gastric fundus to TXB2 and epoxymethano analogs of PGH2. 1980 Adv Prostaglandin Thromboxane Res pmid:6103666
Harris RH et al. Relationship of TXB2 and 6-keto PGF1 alpha to the hemodynamic changes during baboon endotoxic shock. 1980 Adv Prostaglandin Thromboxane Res pmid:6768234
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Kadowitz PJ and Hyman AL Comparative effects of thromboxane B2 on the canine and feline pulmonary vascular bed. 1980 J. Pharmacol. Exp. Ther. pmid:7365689
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Subbiah MT et al. Studies of aggregation and thromboxane B2 synthesis in avian thrombocytes: comparison between atherosclerosis-susceptible and resistant breeds. 1980 Thromb. Haemost. pmid:7455983
Pace-Asciak CR and Edwards NS Tetranor thromboxane B2 is the principal urinary catabolite formed after i.v. infusion of thromboxane B2 in the rat. 1980 Biochem. Biophys. Res. Commun. pmid:7458943
Viinikka L and Ylikorkala O Measurement of thromboxane B2 in human plasma or serum by radioimmunoassay. 1980 Prostaglandins pmid:7465865
Lagarde M et al. Increase of platelet thromboxane A2 formation and of its plasmatic half-life in diabetes mellitus. 1980 Thromb. Res. pmid:7466751
Lewy RI et al. Thromboxane release during pacing-induced angina pectoris: possible vasoconstrictor influence on the coronary vasculature. 1980 Circulation pmid:7371128
McManus LM et al. Thromboxane B2 (TxB2) release during IgE anaphylaxis in the rabbit. 1980 J. Immunol. pmid:7430618
Vanderhoek JY et al. 15-hydroxy-5,8,11,13-eicosatetraenoic acid: A potent and selective inhibitor of platelet lipoxygenase. 1980 J. Biol. Chem. pmid:6771259
Ali M et al. Inhibition of human platelet cyclooxygenase by alpha-tocopherol. 1980 Prostaglandins Med pmid:6771778