| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Airway Obstruction | D000402 | 13 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Graft Occlusion, Vascular | D006083 | 11 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bing RJ et al. | Nitric oxide, prostanoids, cyclooxygenase, and angiogenesis in colon and breast cancer. | 2001 | Clin. Cancer Res. | pmid:11705852 |
| Jilma-Stohlawetz P et al. | Impaired platelet function among platelet donors. | 2001 | Thromb. Haemost. | pmid:11583322 |
| Blann AD et al. | Changes in endothelial, leucocyte and platelet markers following contrast medium injection during angiography in patients with peripheral artery disease. | 2001 | Br J Radiol | pmid:11560828 |
| Martinuzzo ME et al. | Increased lipid peroxidation correlates with platelet activation but not with markers of endothelial cell and blood coagulation activation in patients with antiphospholipid antibodies. | 2001 | Br. J. Haematol. | pmid:11564073 |
| Van Solingen RM et al. | Comparison of the effects of ketoprofen on platelet function in the presence and absence of aspirin. | 2001 | Am. J. Med. | pmid:11566459 |
| Chen CH et al. | [Simultaneously analysis of 15 parameters in the patients with the liver-blood deficiency syndrome]. | 2001 | Hunan Yi Ke Da Xue Xue Bao | pmid:12536728 |
| Ploner F et al. | Effects of combined selective iNOS inhibition and peroxynitrite blockade during endotoxemia in pigs. | 2001 | Shock | pmid:11508865 |
| Diebolt M et al. | Wine polyphenols decrease blood pressure, improve NO vasodilatation, and induce gene expression. | 2001 | Hypertension | pmid:11509469 |
| Tomida T et al. | Altered expression of prostacyclin synthase in a subset of the thick ascending limb cells and mesangial cells in 5/6-nephrectomized rats. | 2001 | Hypertens. Res. | pmid:11510754 |
| Valeri CR et al. | Anemia-induced increase in the bleeding time: implications for treatment of nonsurgical blood loss. | 2001 | Transfusion | pmid:11493727 |
| Ogata K et al. | Attenuation of ischemia and reperfusion injury of canine livers by inhibition of type II phospholipase A2 with LY329722. | 2001 | Transplantation | pmid:11374398 |
| Coelho-Filho OR et al. | Pravastatin reduces myocardial lesions induced by acute inhibition of nitric oxide biosynthesis in normocholesterolemic rats. | 2001 | Int. J. Cardiol. | pmid:11461744 |
| Guyton K et al. | Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation. | 2001 | J. Leukoc. Biol. | pmid:11310850 |
| Oketani K et al. | In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production. | 2001 | Eur. J. Pharmacol. | pmid:11430933 |
| Feng TC et al. | Effect of valsartan and captopril in rabbit carotid injury. Possible involvement of bradykinin in the antiproliferative action of the renin-angiotensin blockade. | 2001 | J Renin Angiotensin Aldosterone Syst | pmid:11881060 |
| Catella-Lawson F et al. | Cyclooxygenase inhibitors and the antiplatelet effects of aspirin. | 2001 | N. Engl. J. Med. | pmid:11752357 |
| Kijima Y et al. | Transcardiac 8-iso-prostaglandin F(2 alpha)generation from acute myocardial infarction heart: insight into abrupt reperfusion and oxidant stress. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11334551 |
| Ochi T and Goto T | Anti-inflammatory activity of a novel selective cyclooxygenase-2 inhibitor, FR140423, on type II collagen-induced arthritis in Lewis rats. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11785783 |
| Gao YJ and Lee RM | Hydrogen peroxide induces a greater contraction in mesenteric arteries of spontaneously hypertensive rats through thromboxane A(2) production. | 2001 | Br. J. Pharmacol. | pmid:11739239 |
| Domoki F et al. | Cyclooxygenase-2 inhibitor NS398 preserves neuronal function after hypoxia/ischemia in piglets. | 2001 | Neuroreport | pmid:11742239 |
| Engström K et al. | Effect of low-dose aspirin in combination with stable fish oil on whole blood production of eicosanoids. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11427037 |
| Karamouzis M et al. | In situ microdialysis of intramuscular prostaglandin and thromboxane in contracting skeletal muscle in humans. | 2001 | Acta Physiol. Scand. | pmid:11350265 |
| Komers R et al. | Immunohistochemical and functional correlations of renal cyclooxygenase-2 in experimental diabetes. | 2001 | J. Clin. Invest. | pmid:11285308 |
| Chen CY and Lin TH | Effects of nickel chloride on human platelets: enhancement of lipid peroxidation, inhibition of aggregation and interaction with ascorbic acid. | 2001 | J. Toxicol. Environ. Health Part A | pmid:11289317 |
| Kawaguchi A et al. | Preventive effect of platelet-activating factor antagonist, Y-24180, against cyclosporine-induced acute nephrotoxicity. | 2001 | Life Sci. | pmid:11228102 |
| Seno K et al. | Pyrrolidine inhibitors of human cytosolic phospholipase A2. Part 2: synthesis of potent and crystallized 4-triphenylmethylthio derivative 'pyrrophenone'. | 2001 | Bioorg. Med. Chem. Lett. | pmid:11229777 |
| Wight NJ et al. | Rofecoxib, a COX-2 inhibitor, does not inhibit human gastric mucosal prostaglandin production. | 2001 | Gastroenterology | pmid:11231941 |
| Franconi F et al. | Effect of gamma-hydroxybutyric acid on human platelet aggregation in vitro. | 2001 | Thromb. Res. | pmid:11369419 |
| Zhang LH et al. | Effects of extract F of red-rooted Salvia on mucosal lesions of gastric corpus and antrum induced by hemorrhagic shock-reperfusion in rats. | 2001 | World J. Gastroenterol. | pmid:11819852 |
| Tuppo EE et al. | Sign of lipid peroxidation as measured in the urine of patients with probable Alzheimer's disease. | 2001 | Brain Res. Bull. | pmid:11397549 |
| Norio K et al. | Eicosanoids and delayed graft function in human renal transplantation. | 2001 | Transplant. Proc. | pmid:11406239 |
| Tran HS et al. | Prostacyclin is neither sufficient alone nor necessary to cause pulmonary dysfunction: results from infusions of prostacyclin and antiprostacyclin antibody in porcine septic shock. | 2001 | Crit. Care Med. | pmid:11445706 |
| Sontag W | Release of mediators by DMSO-differentiated HL-60 cells exposed to electric interferential current and the requirement of biochemical prestimulation. | 2001 | Int. J. Radiat. Biol. | pmid:11403712 |
| Shah AA et al. | Selective inhibition of COX-2 in humans is associated with less gastrointestinal injury: a comparison of nimesulide and naproxen. | 2001 | Gut | pmid:11171823 |
| Yeh CH et al. | Pharmacological characterization and antithrombotic effect of agkistin, a platelet glycoprotein Ib antagonist. | 2001 | Br. J. Pharmacol. | pmid:11181425 |
| Sunose Y et al. | The effect of cyclooxygenase-2 inhibitor FK3311 on ischemia-reperfusion injury in a canine total hepatic vascular exclusion model. | 2001 | J. Am. Coll. Surg. | pmid:11192923 |
| Arifah AK et al. | Pharmacodynamics and pharmacokinetics of ketoprofen enantiomers in sheep. | 2001 | Am. J. Vet. Res. | pmid:11197566 |
| Carvalho CR et al. | Antigen-induced bronchial hyperreactivity and bronchopulmonary inflammation in rats: effect of TNF receptor binding protein. | 2001 | Exp. Lung Res. | pmid:11258800 |
| Suliman HB et al. | Prevention of influenza-induced lung injury in mice overexpressing extracellular superoxide dismutase. | 2001 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:11133496 |
| MalatyalioÄŸlu E et al. | Levels of stable metabolites of prostacyclin and thromboxane A2 and their ratio in normotensive and preeclamptic pregnant women during the antepartum and postpartum periods. | 2000 May-Jun | J Matern Fetal Med | pmid:10914626 |
| Parker CR et al. | Umbilical cord serum levels of thromboxane B2 in term infants of women who participated in a placebo-controlled trial of low-dose aspirin. | 2000 Jul-Aug | J Matern Fetal Med | pmid:11048830 |
| Demasi M et al. | Assay of cyclooxygenase-1 and 2 in human monocytes. | 2000 | Inflamm. Res. | pmid:11211927 |
| Yang G et al. | Effects of prostaglandins and leukotrienes on hypoxic pulmonary vasoconstriction in rats. | 2000 | J. Tongji Med. Univ. | pmid:11215045 |
| Kitano T et al. | Unwashed shed blood infusion causes deterioration in right ventricular function after coronary artery surgery. | 2000 | Anaesth Intensive Care | pmid:11153289 |
| Ferry DR et al. | A phase II study of the 5-lipoxygenase inhibitor, CV6504, in advanced pancreatic cancer: correlation of clinical data with pharmacokinetic and pharmacodynamic endpoints. | 2000 | Ann. Oncol. | pmid:11061613 |
| Ciabattoni G et al. | In vivo lipid peroxidation and platelet activation in cystic fibrosis. | 2000 | Am. J. Respir. Crit. Care Med. | pmid:11029317 |
| Zeng W and Zhang M | [Relationship between the alteration of 6-keto-PGF1 alpha and TXB2 in cervical mucus of patients with threatened preterm labor and the efficacy of magnesium sulfate treatment]. | 2000 | Hua Xi Yi Ke Da Xue Xue Bao | pmid:12501615 |
| Khan HH et al. | Plasma CPU-86017 concentrations regarding suppression of ouabain-induced cardiac arrhythmias and decrease of heart rate in guinea pigs. | 2000 | Acta Pharmacol. Sin. | pmid:11501061 |
| Wang W et al. | Effects of magnesium lithospermate B on aggregation and 5-HT release in rabbit washed platelets. | 2000 | Acta Pharmacol. Sin. | pmid:11501172 |
| Boatman RJ et al. | Covalent protein adducts of hydroquinone in tissues from rats: quantitation of sulfhydryl-bound forms following single gavage or intraperitoneal administration or repetitive gavage administration. | 2000 | Chem. Res. Toxicol. | pmid:10995259 |
| Montini G et al. | Renal glomerular response to the inhibition of prostaglandin E2 synthesis and protein loading after the relief of unilateral ureteropelvic junction obstruction. | 2000 | J. Urol. | pmid:10647684 |
| Chou TC et al. | Mechanism of inhibition of platelet aggregation by HCL-31D. | 2000 | Eur. J. Pharmacol. | pmid:10650152 |
| Xu L et al. | [Clinical and experimental study on effect of Chanbei Kechuanping in treating bronchial asthma]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11789166 |
| Han G et al. | [Inhibitory effect of panicoin on platelet activation and its mechanism]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11789213 |
| Jacobi KE et al. | Determination of eicosanoid and cytokine production in salvaged blood, stored red blood cell concentrates, and whole blood. | 2000 | J Clin Anesth | pmid:10818321 |
| Tanus-Santos JE et al. | Endothelin ET(A) receptor antagonism attenuates the pressor effects of nicotine in rats. | 2000 | Eur. J. Pharmacol. | pmid:10822051 |
| Turpeinen AM et al. | Similar responses in hemostatic factors after consumption of wholemeal rye bread and low-fiber wheat bread. | 2000 | Eur J Clin Nutr | pmid:10822290 |
| Sane S et al. | Eicosapentaenoic acid reduces pulmonary edema in endotoxemic rats. | 2000 | J. Surg. Res. | pmid:10945939 |
| Rahman K and Billington D | Dietary supplementation with aged garlic extract inhibits ADP-induced platelet aggregation in humans. | 2000 | J. Nutr. | pmid:11053504 |
| De Somer F et al. | Phosphorylcholine coating of extracorporeal circuits provides natural protection against blood activation by the material surface. | 2000 | Eur J Cardiothorac Surg | pmid:11053824 |
| Naito Y et al. | Increase in blood pressure with enhanced Na+, K+ -ATPase activity in stroke-prone spontaneously hypertensive rats after 4-weeks intake of rapeseed oil as the sole dietary fat. | 2000 | Pharmacol. Toxicol. | pmid:11068856 |
| Van Hecken A et al. | Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers. | 2000 | J Clin Pharmacol | pmid:11028250 |
| Boyle JR et al. | Endovascular AAA repair attenuates the inflammatory and renal responses associated with conventional surgery. | 2000 | J. Endovasc. Ther. | pmid:11032254 |
| De La Cruz JP et al. | Antithrombotic potential of olive oil administration in rabbits with elevated cholesterol. | 2000 | Thromb. Res. | pmid:11113274 |
| Darlametsos IE et al. | Effect of nifedipine in cyclosporine-induced nephrotoxicity in rats: roles of the thromboxane and endothelin systems. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11090252 |
| Cruz MA et al. | Vascular reactivity to angiotensin II and eicosanoid production in the human placenta from term and preterm pregnancy. | 2000 | Gynecol. Obstet. Invest. | pmid:11093047 |
| Kasahara M et al. | Effect of FK3311 on ischemia-reperfusion injury in canine pulmonary models. | 2000 | Transplant. Proc. | pmid:11120230 |
| De Jong A et al. | Antiphospholipid antibodies and platelets. | 2000 | Curr Rheumatol Rep | pmid:11123065 |
| Buccellati C et al. | Tramadol anti-inflammatory activity is not related to a direct inhibitory action on prostaglandin endoperoxide synthases. | 2000 | Eur J Pain | pmid:11124014 |
| Basu S et al. | Conjugated linoleic acid induces lipid peroxidation in men with abdominal obesity. | 2000 | Clin. Sci. | pmid:11099394 |
| Filipov NM et al. | Anti-inflammatory effects of ergotamine in steers. | 2000 | Proc. Soc. Exp. Biol. Med. | pmid:11044256 |
| Delemarre FM et al. | Urinary prostaglandin excretion in pregnancy: the effect of dietary sodium restriction. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11049696 |
| Tsikas D et al. | Solid- and liquid-phase extraction for the gas chromatographic-tandem mass spectrometric quantification of 2,3-dinor-thromboxane B2 and 2,3-dinor-6-oxo-prostaglandin F1 alpha in human urine. | 2000 | J Chromatogr A | pmid:10941682 |
| Greenberg HE et al. | A new cyclooxygenase-2 inhibitor, rofecoxib (VIOXX), did not alter the antiplatelet effects of low-dose aspirin in healthy volunteers. | 2000 | J Clin Pharmacol | pmid:11185674 |
| Cracowski JL et al. | Human internal mammary artery contraction by isoprostaglandin f(2alpha) type-III [8-iso-prostaglandin F(2alpha)]. | 2000 | Eur. J. Pharmacol. | pmid:10844110 |
| Wang JS et al. | Effect of strenuous arm exercise on oxidized-LDL-potentiated platelet activation in individuals with spinal cord injury. | 2000 | Thromb. Haemost. | pmid:10928481 |
| WÅ‚odarczyk Z et al. | Effects of pentoxifylline treatment on delayed graft function in cadaveric kidney recipients. | 2000 | Transplant. Proc. | pmid:10995988 |
| de Jong CL et al. | Maternal thromboxane and prostacyclin levels in relation to fetal birth weight. | 2000 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:11000507 |
| Jacoby RF et al. | The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis. | 2000 | Cancer Res. | pmid:11016626 |
| Ogura Y et al. | Chemoprevention of biliary carcinogenesis in syrian hamsters by the novel carboxamide derivative IS-741 after initiation with N-nitrosobis(2-oxopropyl)amine (BOP). | 2000 | Carcinogenesis | pmid:10910946 |
| Sugimoto KI et al. | Delayed hypotensive effect of the thromboxane A2/prostaglandin H2 receptor antagonist S-1452 in spontaneously hypertensive rats. | 2000 | Clin. Exp. Pharmacol. Physiol. | pmid:10901388 |
| Wang Z et al. | [Clinical and experimental study on treatment of bronchial asthma with pingchuan oral liquid]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938808 |
| Köfeler HC et al. | Effect of cytochrome P-450 inhibitors econazole, bifonazole and clotrimazole on prostanoid formation. | 2000 | Br. J. Pharmacol. | pmid:10903961 |
| Yu K et al. | [Clinical observation on treatment of pediatric intractable nephropathy with modified taohong siwu decoction]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938829 |
| Toft G et al. | Intravenously and topically applied magnesium in the prevention of arterial thrombosis. | 2000 | Thromb. Res. | pmid:10904104 |
| Shi X et al. | [Effects of Salvia miltiorrhiza compound injection on serum endothelin, prostaglandin I2/thromboxane A2 ratio alteration following myocardial ischemia-reperfusion in patients undergoing intracardiac surgery]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938858 |
| Giedrojć J et al. | [Investigation of prostaglandins in supernatant of cultured monocytes]. | 2000 | Prz. Lek. | pmid:10907365 |
| Miao X et al. | [Effect of yinchen dandao decoction on plasma fibronectin, biliary thromboxane A2 and prostaglandin I2 in human and animal suffering from acute cholangitis]. | 2000 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:11938860 |
| Momi S et al. | Involvement of platelets in experimental mouse trypanosomiasis: evidence of mouse platelet cytotoxicity against Trypanosoma equiperdum. | 2000 | Exp. Parasitol. | pmid:10910715 |
| Moon CH et al. | Mechanism for antiplatelet effect of onion: AA release inhibition, thromboxane A(2)synthase inhibition and TXA(2)/PGH(2)receptor blockade. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883058 |
| Lasserre B et al. | Modifications in the TXA(2) and PGI(2) plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the rabbit. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883059 |
| Arakida Y et al. | Effect of combined leukotriene D(4) and thromboxane A(2) receptor antagonist on mediator-controlled resistance in guinea pigs. | 2000 | Eur. J. Pharmacol. | pmid:10969159 |
| Bereczki C et al. | The roles of platelet function, thromboxane, blood lipids and nitric oxide in hypertension of children and adolescents. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10883060 |
| Carty E et al. | Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: anti-inflammatory profile in inflammatory bowel disease. | 2000 | Aliment. Pharmacol. Ther. | pmid:10848666 |
| Armstrong RA et al. | No effect of dietary trans isomers of alpha-linolenic acid on platelet aggregation and haemostatic factors in european healthy men. The TRANSLinE study. | 2000 | Thromb. Res. | pmid:11108899 |
| Suzuki N et al. | Difference in urinary LTE4 and 11-dehydro-TXB2 excretion in asthmatic patients. | 2000 | Prostaglandins Other Lipid Mediat. | pmid:11060902 |
| Wu TM et al. | Inhibitory effect of hexapeptide (RGRHGD) on platelet aggregation. | 2000 | Thromb. Res. | pmid:10674405 |
| Jacobi K et al. | Plasma levels of eicosanoids after transfusion of intraoperatively salvaged blood. | 2000 | Vox Sang. | pmid:10729809 |
| Rioja I et al. | An anti-inflammatory ditriazine inhibiting leukocyte functions and expression of inducible nitric oxide synthase and cyclo-oxygenase-2. | 2000 | Eur. J. Pharmacol. | pmid:10844115 |
| Tran HS et al. | The cardiovascular hemodynamics and leukotriene kinetics during prostacyclin and anti-prostacyclin antibody infusions in septic shock. | 2000 | Shock | pmid:10847636 |