Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Uremia D014511 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypoxia D000860 23 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Kitchen EA et al. Chemotactic activity of thromboxane B2, prostaglandins and their metabolites for polymorphonuclear leucocytes. 1978 Prostaglandins pmid:704931
Sors H et al. Analytical methods for thromboxane B2 measurement and validation of radioimmunoassay by gas liquid chromatography-mass spectrometry. 1978 Prostaglandins pmid:704933
Turk J et al. Fluorescent derivatives of prostaglandins and thromboxanes for liquid chromatography. 1978 Prostaglandins pmid:704934
Raz A and Aharony D Prostaglandin biosynthesis in platelets: demonstration and role of prostaglandin H2 leads to E2 isomerase. 1978 Res. Commun. Chem. Pathol. Pharmacol. pmid:705027
Chang WC et al. Inhibition of thromboxane B2 and 6-ketoprostaglandin F1 alpha formation by anti-inflammatory drugs in carrageenin-induced granuloma. 1978 Biochem. Pharmacol. pmid:619892
Goetzl EJ and Gorman RR Chemotactic and chemokinetic stimulation of human eosinophil and neutrophil polymorphonuclear leukocytes by 12-L-hydroxy-5,8,10-heptadecatrienoic acid (HHT). 1978 J. Immunol. pmid:621391
Hamberg M et al. A method for measurement of platelet regeneration in man. 1978 Prostaglandins Med pmid:104315
Lagarde M et al. Impairment of platelet thromboxane A2 generation and of the platelet release reaction in two patients with congenital deficiency of platelet cyclo-oxygenase. 1978 Br. J. Haematol. pmid:205238
Crawford A et al. Rat osteogenic sarcoma cells: comparison of the effects of prostaglandins E1, E2, I2 (prostacyclin), 6-keto F1alpha and thromboxane B2 on cyclic AMP production and adenylate cyclase activity. 1978 Biochem. Biophys. Res. Commun. pmid:212039
Trang LE et al. Levels of prostaglandins F2 alpha and E2 and thromboxane B2 in joint fluid in rheumatoid arthritis. 1977 Scand. J. Rheumatol. pmid:929121
Smith AG et al. Gas-liquid chromatography-mass spectrometry of thromboxane B2 and its detection in semen and human aorta by selected ion monitoring. 1977 J. Chromatogr. pmid:562354
Abdel-Halim MS et al. Identification of prostaglandin D2 as a major prostaglandin in homogenates of rat brain. 1977 Prostaglandins pmid:594367
Williams KI and Downing I Prostaglandin and thromboxane production by rat decidual microsomes. 1977 Prostaglandins pmid:594385
Ali M et al. Synthesis of thromboxane B2 and prostaglandins by bovine gastric mucosal microsomes. 1977 Prostaglandins pmid:594386
Wasserman MA and Griffin RL Thromboxane B2--comparative bronchoactivity in experimental systems. 1977 Eur. J. Pharmacol. pmid:590340
Poyser NL Identification of thromboxane B2 in guinea-pig uterine homogenates. 1977 Experientia pmid:590434
Fitzpatrick FA et al. A radioimmunoassay for thromboxane B2. 1977 Anal. Biochem. pmid:907115
Murota SI et al. The effects of thromboxane B2 and 6-ketoprostaglandin F1alpha on cultured fibroblasts. 1977 Biochim. Biophys. Acta pmid:911847
Roberts LJ et al. Metabolism of thromboxane B2 in man. Identification of the major urinary metabolite. 1977 J. Biol. Chem. pmid:914816
Ali M et al. Synthesis of prostaglandin D2 and thromboxane B2 by human platelets. 1977 Thromb. Res. pmid:918907
Burka JF and Garland LG A possible modulatory role for prostacyclin (PGI2) INIgGa-induced release of slow-reacting substance of anaphylaxis in rats. 1977 Br. J. Pharmacol. pmid:339980
Knapp HR et al. Ionophores stimulate prostaglandin and thromboxane biosynthesis. 1977 Proc. Natl. Acad. Sci. U.S.A. pmid:270668
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