| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Airway Obstruction | D000402 | 13 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Graft Occlusion, Vascular | D006083 | 11 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Canales A et al. | The effect of consuming meat enriched in walnut paste on platelet aggregation and thrombogenesis varies in volunteers with different apolipoprotein A4 genotype. | 2010 Sep-Oct | Nutr Hosp | pmid:21336431 |
| Fuchs I et al. | Platelet hyperfunction is decreased by additional aspirin loading in patients presenting with myocardial infarction on daily aspirin therapy. | 2010 | Crit. Care Med. | pmid:20400900 |
| Steib CJ et al. | Intraperitoneal LPS amplifies portal hypertension in rat liver fibrosis. | 2010 | Lab. Invest. | pmid:20212458 |
| Dragani A et al. | The contribution of cyclooxygenase-1 and -2 to persistent thromboxane biosynthesis in aspirin-treated essential thrombocythemia: implications for antiplatelet therapy. | 2010 | Blood | pmid:19887674 |
| Kienzler JL et al. | Systemic bioavailability of topical diclofenac sodium gel 1% versus oral diclofenac sodium in healthy volunteers. | 2010 | J Clin Pharmacol | pmid:19841157 |
| Würtz M et al. | The antiplatelet effect of aspirin is reduced by proton pump inhibitors in patients with coronary artery disease. | 2010 | Heart | pmid:19910291 |
| Koeberle A et al. | The molecular pharmacology and in vivo activity of 2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid (YS121), a dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase. | 2010 | J. Pharmacol. Exp. Ther. | pmid:19934399 |
| Armstrong PC et al. | Reduction of platelet thromboxane A2 production ex vivo and in vivo by clopidogrel therapy. | 2010 | J. Thromb. Haemost. | pmid:19995405 |
| Nørregaard R et al. | Urinary tract obstruction induces transient accumulation of COX-2-derived prostanoids in kidney tissue. | 2010 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:20147610 |
| Carroll RC et al. | Post interventional cardiology urinary thromboxane correlates with PlateletMapping detected aspirin resistance. | 2010 | Thromb. Res. | pmid:19962724 |
| Dragani A et al. | Clinical and laboratory phenotype associated with the aspirin-like defect. | 2010 | Br. J. Haematol. | pmid:19814736 |
| Maddens BE et al. | Validation of immunoassays for the candidate renal markers C-reactive protein, immunoglobulin G, thromboxane B2 and retinol binding protein in canine urine. | 2010 | Vet. Immunol. Immunopathol. | pmid:19815297 |
| Derhaschnig U et al. | Effects of aspirin and NO-aspirin (NCX 4016) on platelet function and coagulation in human endotoxemia. | 2010 | Platelets | pmid:20608787 |
| Cheng Y and Li ZK | [Changes of neurotransmitter endothelin, thromboxance B2 and 6-keto-prostaglandin F1 alpha in patients with chronic pulmonary heart disease]. | 2010 | Nan Fang Yi Ke Da Xue Xue Bao | pmid:20584647 |
| Boutaud O and Oates JA | Study of inhibitors of the PGH synthases for which potency is regulated by the redox state of the enzymes. | 2010 | Methods Mol. Biol. | pmid:20645166 |
| Kawaguchi T et al. | The human megakaryocytic cell line UT-7/TPO expresses functional platelet agonist signals mediated through GPVI and thromboxane receptor. | 2010 | Cell Biol. Int. | pmid:20522022 |
| Alusik S et al. | The inhibitory effect of statins on urinary 11-dehydrothromboxane levels. | 2010 | Int Angiol | pmid:20502413 |
| Mangalpally KK et al. | Platelet activation patterns in platelet size sub-populations: differential responses to aspirin in vitro. | 2010 | J. Thromb. Thrombolysis | pmid:20502945 |
| Cholette JM et al. | Aspirin resistance following pediatric cardiac surgery. | 2010 | Thromb. Res. | pmid:20550971 |
| Youssef DT et al. | New anti-inflammatory sterols from the Red Sea sponges Scalarispongia aqabaensis and Callyspongia siphonella. | 2010 | Nat Prod Commun | pmid:20184014 |
| Kidson-Gerber G et al. | Serum thromboxane B2 compared to five other platelet function tests for the evaluation of aspirin effect in stable cardiovascular disease. | 2010 | Heart Lung Circ | pmid:20144559 |
| Montine TJ et al. | Elevated ratio of urinary metabolites of thromboxane and prostacyclin is associated with adverse cardiovascular events in ADAPT. | 2010 | PLoS ONE | pmid:20174466 |
| King JN et al. | In vitro and ex vivo inhibition of canine cyclooxygenase isoforms by robenacoxib: a comparative study. | 2010 | Res. Vet. Sci. | pmid:20004922 |
| Zisman E et al. | Platelet function recovery after cessation of aspirin: preliminary study of volunteers and surgical patients. | 2010 | Eur J Anaesthesiol | pmid:20035230 |
| Butler BD et al. | Circadian study of decompression sickness symptoms and response-associated variables in rats. | 2010 | Chronobiol. Int. | pmid:20205563 |
| Oldenhof J et al. | Effect of maximum OTC doses of naproxen sodium or acetaminophen on low-dose aspirin inhibition of serum thromboxane B2. | 2010 | Curr Med Res Opin | pmid:20429831 |
| Boizel R et al. | Regulation of oxidative stress and inflammation by glycaemic control: evidence for reversible activation of the 5-lipoxygenase pathway in type 1, but not in type 2 diabetes. | 2010 | Diabetologia | pmid:20535444 |
| Liu H et al. | Aspirin inhibits fractalkine expression in atherosclerotic plaques and reduces atherosclerosis in ApoE gene knockout mice. | 2010 | Cardiovasc Drugs Ther | pmid:19997773 |
| Cavalca V et al. | Simultaneous quantification of 8-iso-prostaglandin-F(2alpha) and 11-dehydro thromboxane B(2) in human urine by liquid chromatography-tandem mass spectrometry. | 2010 | Anal. Biochem. | pmid:19825360 |
| Parmar JH et al. | Significant prostacyclin/thromboxane level imbalance after lower limb arterial angioplasty: a possible platelet function alteration. | 2010 | J Vasc Interv Radiol | pmid:20800778 |
| Dharmasaroja PA and Sae-Lim S | Effects of different doses, enteric-coated preparation of aspirin, and sex on urinary 11-dehydrothromboxane B2 in healthy volunteers. | 2010 | Blood Coagul. Fibrinolysis | pmid:20689403 |
| Kawabata K et al. | Inhibition of secretory phospholipase A2 activity attenuates acute cardiogenic pulmonary edema induced by isoproterenol infusion in mice after myocardial infarction. | 2010 | J. Cardiovasc. Pharmacol. | pmid:20625313 |
| Milara J et al. | Cigarette smoke exposure up-regulates endothelin receptor B in human pulmonary artery endothelial cells: molecular and functional consequences. | 2010 | Br. J. Pharmacol. | pmid:20698855 |
| Anauate MC et al. | Effect of isolated fractions of Harpagophytum procumbens D.C. (devil's claw) on COX-1, COX-2 activity and nitric oxide production on whole-blood assay. | 2010 | Phytother Res | pmid:20812280 |
| Yassine HN et al. | Clinical determinants of aspirin resistance in diabetes. | 2010 | Diabetes Res. Clin. Pract. | pmid:20719400 |
| Würtz M et al. | Patients with previous definite stent thrombosis have a reduced antiplatelet effect of aspirin and a larger fraction of immature platelets. | 2010 | JACC Cardiovasc Interv | pmid:20723855 |
| Kim SY et al. | Platelet anti-aggregation activities of compounds from Cinnamomum cassia. | 2010 | J Med Food | pmid:20828311 |
| Bao YM et al. | [Effect of precondition with GBE50 and Salviae miltionrrhizae on cycloxygenase-2 and its downstream effectors contents in ischemia/reperfusion myocardium]. | 2010 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:21066890 |
| De la Cruz JP et al. | Differences in the in vitro antiplatelet effect of dexibuprofen, ibuprofen, and flurbiprofen in human blood. | 2010 | Anesth. Analg. | pmid:21048099 |
| Qu C et al. | Chronic inhibition of nitric-oxide synthase potentiates endothelium-dependent contractions in the rat aorta by augmenting the expression of cyclooxygenase-2. | 2010 | J. Pharmacol. Exp. Ther. | pmid:20444882 |
| Renda G et al. | Inconsistency of different methods for assessing ex vivo platelet function: relevance for the detection of aspirin resistance. | 2010 | Haematologica | pmid:21123440 |
| Iagoda AV and Gladkikh NN | [Thromboxane-prostacyclin balance and platelet aggregability in patients with minor cardiac abnormalities]. | 2010 | Ter. Arkh. | pmid:21086621 |
| Warner JH et al. | Adaptive regression modeling of biomarkers of potential harm in a population of U.S. adult cigarette smokers and nonsmokers. | 2010 | BMC Med Res Methodol | pmid:20233412 |
| Bollinger JG et al. | Improved sensitivity mass spectrometric detection of eicosanoids by charge reversal derivatization. | 2010 | Anal. Chem. | pmid:20704368 |
| Fukushima H et al. | Mechanisms underlying early development of pulmonary vascular obstructive disease in Down syndrome: An imbalance in biosynthesis of thromboxane A2 and prostacyclin. | 2010 | Am. J. Med. Genet. A | pmid:20583254 |
| Laguta PS et al. | [Aspirin resistance in patients with stable ischemic heart disease]. | 2010 | Kardiologiia | pmid:21526557 |
| Sato R et al. | Inhibition of secretory phospholipase A2 activity attenuates lipopolysaccharide-induced acute lung injury in a mouse model. | 2010 | Exp. Lung Res. | pmid:20426527 |
| Ren R et al. | Protective effects of Danshensu on liver injury induced by omethoate in rats. | 2010 | Toxicol. Mech. Methods | pmid:20843270 |
| Watanabe H et al. | [Thromboxane A2 (TXA2), thromboxane B2(TXB2)]. | 2010 | Nippon Rinsho | pmid:20963856 |
| Wang BZ et al. | [Association of the Pro1770Leu polymorphism in CYP5A1 gene with myocardial infarction in Uigur population of Xinjiang]. | 2010 | Zhonghua Yi Xue Yi Chuan Xue Za Zhi | pmid:20931532 |
| Huang HC et al. | Simvastatin effects on portal-systemic collaterals of portal hypertensive rats. | 2010 | J. Gastroenterol. Hepatol. | pmid:20659230 |
| Wang BZ et al. | [Association of Rs10487667 genetic polymorphism of thromboxane synthase with myocardial infarction in Uigur population of Xinjiang]. | 2010 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:21215134 |
| Ge Y et al. | [Effect of ulinastatin on thromboxane Bâ‚‚ and deep vein thrombosis in elderly patients after hip joint replacement]. | 2010 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:21200097 |
| Ferrante E et al. | Determinants of thromboxane biosynthesis in rheumatoid arthritis: Role of RAGE and oxidant stress. | 2010 | Free Radic. Biol. Med. | pmid:20541603 |
| Hepgül G et al. | Preventive effect of pentoxifylline on acute radiation damage via antioxidant and anti-inflammatory pathways. | 2010 | Dig. Dis. Sci. | pmid:19294507 |
| Antonino MJ et al. | Antiplatelet effects of aspirin with phytosterols: comparison with non-enteric coated aspirin alone. | 2010 | Thromb. Res. | pmid:19446864 |
| Iwasaki W et al. | Changes in the fatty acid composition of the liver with the administration of N-3 polyunsaturated fatty acids and the effects on warm ischemia/reperfusion injury in the rat liver. | 2010 | Shock | pmid:19543146 |
| Yen PL et al. | Effects of deep-frying oil on blood pressure and oxidative stress in spontaneously hypertensive and normotensive rats. | 2010 | Nutrition | pmid:19592221 |
| Huntjens DR et al. | Impact of chronic inflammation on the pharmacokinetic-pharmacodynamic relationship of naproxen. | 2010 | Eur J Pain | pmid:19679500 |
| Santilli F et al. | Postprandial hyperglycemia is a determinant of platelet activation in early type 2 diabetes mellitus. | 2010 | J. Thromb. Haemost. | pmid:20088941 |
| Addad F et al. | Response variability to aspirin and one-year prediction of vascular events in patients with stable coronary artery disease. | 2010 | J. Thromb. Thrombolysis | pmid:19381450 |
| De La Cruz JP et al. | Virgin olive oil administration improves the effect of aspirin on retinal vascular pattern in experimental diabetes mellitus. | 2010 | Br. J. Nutr. | pmid:20350343 |
| Smock KJ and Rodgers GM | Laboratory evaluation of aspirin responsiveness. | 2010 | Am. J. Hematol. | pmid:20229592 |
| Yao HX et al. | [The study of relationship between platelet function and thrombus in patients with essential thrombocythaemia]. | 2010 | Zhonghua Yi Xue Za Zhi | pmid:20356540 |
| Dołegowska B et al. | Dynamics of thromboxane level changes during early phase of allograft reperfusion. | 2009 Sep-Oct | Clin Transplant | pmid:19298388 |
| Tantry US et al. | Aspirin resistance. | 2009 Sep-Oct | Prog Cardiovasc Dis | pmid:19732606 |
| Thomson VS et al. | Aspirin resistance in Indian patients with coronary artery disease and cardiovascular events. | 2009 Oct-Dec | J Postgrad Med | pmid:20083870 |
| Goodman L et al. | Effects of firocoxib and tepoxalin on healing in a canine gastric mucosal injury model. | 2009 Jan-Feb | J. Vet. Intern. Med. | pmid:19175721 |
| Guerrero MD et al. | Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression. | 2009 | Eur. J. Pharmacol. | pmid:19686718 |
| Hu Y et al. | Chinese herbal medicinal ingredients inhibit secretion of IL-6, IL-8, E-selectin and TXB2 in LPS-induced rat intestinal microvascular endothelial cells. | 2009 | Immunopharmacol Immunotoxicol | pmid:19874221 |
| Dietrich-Muszalska A and Olas B | Isoprostenes as indicators of oxidative stress in schizophrenia. | 2009 | World J. Biol. Psychiatry | pmid:19673085 |
| Lowe FJ et al. | Evaluation of biomarkers of exposure and potential harm in smokers, former smokers and never-smokers. | 2009 | Clin. Chem. Lab. Med. | pmid:19676143 |
| Stanke-Labesque F et al. | Increased urinary leukotriene E4 excretion in obstructive sleep apnea: effects of obesity and hypoxia. | 2009 | J. Allergy Clin. Immunol. | pmid:19596146 |
| Huntjens DR et al. | Differences in the sensitivity of behavioural measures of pain to the selectivity of cyclo-oxygenase inhibitors. | 2009 | Eur J Pain | pmid:18774319 |
| Correa JA et al. | Virgin olive oil polyphenol hydroxytyrosol acetate inhibits in vitro platelet aggregation in human whole blood: comparison with hydroxytyrosol and acetylsalicylic acid. | 2009 | Br. J. Nutr. | pmid:18775097 |
| Hynninen VV et al. | Oral voriconazole and miconazole oral gel produce comparable effects on the pharmacokinetics and pharmacodynamics of etoricoxib. | 2009 | Eur. J. Clin. Pharmacol. | pmid:18777173 |
| Muir AR et al. | Assessment of aspirin resistance varies on a temporal basis in patients with ischaemic heart disease. | 2009 | Heart | pmid:18697805 |
| Foudi N et al. | Selective cyclooxygenase-2 inhibition directly increases human vascular reactivity to norepinephrine during acute inflammation. | 2009 | Cardiovasc. Res. | pmid:18952694 |
| Rogers LK et al. | Differential responses in the lungs of newborn mouse pups exposed to 85% or >95% oxygen. | 2009 | Pediatr. Res. | pmid:18703992 |
| Fernández-Arche A et al. | Long-chain fatty alcohols from pomace olive oil modulate the release of proinflammatory mediators. | 2009 | J. Nutr. Biochem. | pmid:18555679 |
| Jespersen B et al. | Differential effects of immunosuppressive drugs on COX-2 activity in vitro and in kidney transplant patients in vivo. | 2009 | Nephrol. Dial. Transplant. | pmid:19193738 |
| Chen SS et al. | Elevated plasma prostaglandins and acetylated histone in monocytes in Type 1 diabetes patients. | 2009 | Diabet. Med. | pmid:19236624 |
| Kanazawa S et al. | Effect of low-dose aspirin for skin rash associated with erlotinib therapy in patients with lung cancer. | 2009 | Platelets | pmid:19172526 |
| Calapai G et al. | Cardiovascular biomarkers in groups of established smokers after a decade of smoking. | 2009 | Basic Clin. Pharmacol. Toxicol. | pmid:19175368 |
| Kapetanovic IM et al. | Comparison of pharmacokinetic and pharmacodynamic profiles of aspirin following oral gavage and diet dosing in rats. | 2009 | Chem. Biol. Interact. | pmid:18992230 |
| Seta F et al. | Renal and cardiovascular characterization of COX-2 knockdown mice. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19357295 |
| Pettinella C et al. | Cyclooxygenase-1 haplotype C50T/A-842G does not affect platelet response to aspirin. | 2009 | Thromb. Haemost. | pmid:19350112 |
| Guagnano MT et al. | Determinants of platelet activation in hypertensives with microalbuminuria. | 2009 | Free Radic. Biol. Med. | pmid:19280705 |
| Lo HM et al. | 2'-Ethoxy-5'-methoxy-2-(5-methylthienyl)chalcone inhibits collagen-induced protein tyrosine phosphorylation and thromboxane formation during platelet aggregation and adhesion. | 2009 | Pharmacology | pmid:19690443 |
| Lauring B et al. | Laropiprant in combination with extended-release niacin does not alter urine 11-dehydrothromboxane B2, a marker of in vivo platelet function, in healthy, hypercholesterolemic, and diabetic subjects. | 2009 | J Clin Pharmacol | pmid:19833861 |
| Eriksson AC et al. | Static platelet adhesion, flow cytometry and serum TXB2 levels for monitoring platelet inhibiting treatment with ASA and clopidogrel in coronary artery disease: a randomised cross-over study. | 2009 | J Transl Med | pmid:19508722 |
| Cattaneo M | Letter by cattaneo regarding article, "incomplete inhibition of thromboxane biosynthesis by acetylsalicylic Acid: determinants and effect on cardiovascular risk". | 2009 | Circulation | pmid:19546394 |
| Schiff M et al. | Platelet inhibitory effects of OTC doses of naproxen sodium compared with prescription dose naproxen sodium and low-dose aspirin. | 2009 | Curr Med Res Opin | pmid:19678751 |
| Cook VL et al. | Effect of firocoxib or flunixin meglumine on recovery of ischemic-injured equine jejunum. | 2009 | Am. J. Vet. Res. | pmid:19645580 |
| Blais N et al. | Response to aspirin in healthy individuals. Cross-comparison of light transmission aggregometry, VerifyNow system, platelet count drop, thromboelastography (TEG) and urinary 11-dehydrothromboxane B(2). | 2009 | Thromb. Haemost. | pmid:19652893 |
| Zhang X et al. | Effect of baicalin on inflammatory mediator levels and microcirculation disturbance in rats with severe acute pancreatitis. | 2009 | Pancreas | pmid:19657312 |
| Liu FC et al. | A new insight of anti-platelet effects of sirtinol in platelets aggregation via cyclic AMP phosphodiesterase. | 2009 | Biochem. Pharmacol. | pmid:19426675 |
| Li L et al. | The anti-inflammatory effects of ZLJ-6, a novel dual cyclooxygenase/5-lipoxygenase inhibitor. | 2009 | Eur. J. Pharmacol. | pmid:19243697 |
| Peng CY et al. | Dietary soy protein selectively reduces renal prostanoids and cyclooxygenases in polycystic kidney disease. | 2009 | Exp. Biol. Med. (Maywood) | pmid:19429858 |
| Li H et al. | [Effect of an integrative medical regimen on levels of vascular endothelial function and hypersensitive C-reactive protein in elderly patients with isolated systolic hypertension]. | 2009 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:19382469 |