| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Airway Obstruction | D000402 | 13 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Graft Occlusion, Vascular | D006083 | 11 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Capodanno D and Angiolillo DJ | Platelet monitoring for PCI: which test is the one to choose? | 2009 | Hamostaseologie | pmid:19882078 |
| Gao XR et al. | Efficacy of different doses of aspirin in decreasing blood levels of inflammatory markers in patients with cardiovascular metabolic syndrome. | 2009 | J. Pharm. Pharmacol. | pmid:19903376 |
| Zuo Y et al. | Gross-total hematoma removal of hypertensive basal ganglia hemorrhages: a long-term follow-up. | 2009 | J. Neurol. Sci. | pmid:19801153 |
| Frelinger AL et al. | Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization. | 2009 | Circulation | pmid:19996015 |
| Kambara T et al. | Propofol suppresses prostaglandin E(2) production in human peripheral monocytes. | 2009 | Immunopharmacol Immunotoxicol | pmid:19951072 |
| Li M et al. | Effects of pathological flow on pulmonary artery endothelial production of vasoactive mediators and growth factors. | 2009 | J. Vasc. Res. | pmid:19571576 |
| McClelland S et al. | Contribution of cyclooxygenase-1 to thromboxane formation, platelet-vessel wall interactions and atherosclerosis in the ApoE null mouse. | 2009 | Atherosclerosis | pmid:18514659 |
| Coates AM et al. | Regular consumption of n-3 fatty acid-enriched pork modifies cardiovascular risk factors. | 2009 | Br. J. Nutr. | pmid:18590592 |
| Xu Y et al. | Urocortin promotes the development of vasculitis in a rat model of thromboangiitis obliterans via corticotrophin-releasing factor type 1 receptors. | 2009 | Br. J. Pharmacol. | pmid:19572944 |
| Zhao L et al. | Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor. | 2009 | Br. J. Pharmacol. | pmid:19220291 |
| Shah KB et al. | The cardioprotective effects of fish oil during pressure overload are blocked by high fat intake: role of cardiac phospholipid remodeling. | 2009 | Hypertension | pmid:19597033 |
| Ulbrich SE et al. | Quantitative characterization of prostaglandins in the uterus of early pregnant cattle. | 2009 | Reproduction | pmid:19470711 |
| Zeng HH et al. | [Effect of safflower injection on pulmonary hypertension in rat during chronic hypoxia and hypercapnia]. | 2009 | Zhongguo Ying Yong Sheng Li Xue Za Zhi | pmid:21186611 |
| Santilli F et al. | Platelet cyclooxygenase inhibition by low-dose aspirin is not reflected consistently by platelet function assays: implications for aspirin "resistance". | 2009 | J. Am. Coll. Cardiol. | pmid:19232899 |
| Lev EI | Aspirin resistance transient laboratory finding or important clinical entity? | 2009 | J. Am. Coll. Cardiol. | pmid:19232900 |
| Bernoud-Hubac N et al. | Low concentrations of reactive gamma-ketoaldehydes prime thromboxane-dependent human platelet aggregation via p38-MAPK activation. | 2009 | Biochim. Biophys. Acta | pmid:19233311 |
| Giraudel JM et al. | Differential inhibition of cyclooxygenase isoenzymes in the cat by the NSAID robenacoxib. | 2009 | J. Vet. Pharmacol. Ther. | pmid:19161453 |
| Basselin M et al. | Imaging elevated brain arachidonic acid signaling in unanesthetized serotonin transporter (5-HTT)-deficient mice. | 2009 | Neuropsychopharmacology | pmid:19145225 |
| Struthmann L et al. | Prothrombotic effects of diclofenac on arteriolar platelet activation and thrombosis in vivo. | 2009 | J. Thromb. Haemost. | pmid:19691487 |
| Omura Y et al. | Severe asthma with markedly increased asbestos of 2 types & TXB2, and markedly reduced acetylcholine, DHEA & drug uptake in parts of upper lungs, & similar abnormalities at respiratory & cardiac center of medulla oblongata: complete elimination of this asthma within 15 days using one optimal dose of astragalus & application of strong red light & EMF neutralizer on respiratory centers of abnormal medulla oblongata. | 2009 | Acupunct Electrother Res | pmid:19711774 |
| Sobotková A et al. | Antioxidants change platelet responses to various stimulating events. | 2009 | Free Radic. Biol. Med. | pmid:19766712 |
| Shen H et al. | Aspirin Resistance in healthy drug-naive men versus women (from the Heredity and Phenotype Intervention Heart Study). | 2009 | Am. J. Cardiol. | pmid:19660620 |
| Leoncini G et al. | In retinal vein occlusion platelet response to thrombin is increased. | 2009 | Thromb. Res. | pmid:19660790 |
| Canales A et al. | Platelet aggregation, eicosanoid production and thrombogenic ratio in individuals at high cardiovascular risk consuming meat enriched in walnut paste. A crossover, placebo-controlled study. | 2009 | Br. J. Nutr. | pmid:19068151 |
| Duda MK et al. | Fish oil, but not flaxseed oil, decreases inflammation and prevents pressure overload-induced cardiac dysfunction. | 2009 | Cardiovasc. Res. | pmid:19015135 |
| Hynninen VV et al. | Voriconazole increases while itraconazole decreases plasma meloxicam concentrations. | 2009 | Antimicrob. Agents Chemother. | pmid:19015346 |
| Kerola M et al. | Effects of nimesulide, acetylsalicylic acid, ibuprofen and nabumetone on cyclooxygenase-1- and cyclooxygenase-2-mediated prostanoid production in healthy volunteers ex vivo. | 2009 | Basic Clin. Pharmacol. Toxicol. | pmid:19152549 |
| O'Donnell ME et al. | The effects of cilostazol on exercise-induced ischaemia-reperfusion injury in patients with peripheral arterial disease. | 2009 | Eur J Vasc Endovasc Surg | pmid:19112032 |
| Bailey SR et al. | Plasma concentrations of endotoxin and platelet activation in the developmental stage of oligofructose-induced laminitis. | 2009 | Vet. Immunol. Immunopathol. | pmid:19091426 |
| Dołegowska B et al. | Platelets arachidonic acid metabolism in patients with essential hypertension. | 2009 | Platelets | pmid:19440924 |
| Ahmad M et al. | Prolonged opportunity for neuroprotection in experimental stroke with selective blockade of cyclooxygenase-2 activity. | 2009 | Brain Res. | pmid:19446533 |
| Mayer K et al. | Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids. | 2009 | Am. J. Respir. Crit. Care Med. | pmid:19136374 |
| Schuijt MP et al. | The interaction of ibuprofen and diclofenac with aspirin in healthy volunteers. | 2009 | Br. J. Pharmacol. | pmid:19466986 |
| Csányi G et al. | Effects of 3-aminopyridine-induced seizures on platelet eicosanoid synthesis. | 2008 May-Jun | Pharmacol Rep | pmid:18622059 |
| Hsu MF et al. | Blockade of cytosolic phospholipase A(2) and 5-lipoxygenase activation in neutrophils by a natural isoflavanquinone abruquinone A. | 2008 | Eur. J. Pharmacol. | pmid:18834875 |
| Kaneko I et al. | Prostaglandin F(2alpha) regulates cytokine responses of mast cells through the receptors for prostaglandin E. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18190789 |
| Parsons JP et al. | Airway inflammation in exercise-induced bronchospasm occurring in athletes without asthma. | 2008 | J Asthma | pmid:18569228 |
| Natarajan G et al. | Chorioamnionitis and ontogeny of circulating prostaglandin and thromboxane in preterm infants. | 2008 | Am J Perinatol | pmid:18726836 |
| Santilli F et al. | Circulating endothelial progenitor cells and residual in vivo thromboxane biosynthesis in low-dose aspirin-treated polycythemia vera patients. | 2008 | Blood | pmid:18541722 |
| Mitsopoulos P et al. | Effectiveness of liposomal-N-acetylcysteine against LPS-induced lung injuries in rodents. | 2008 | Int J Pharm | pmid:18694812 |
| Yokoyama Y et al. | Up-regulated thromboxane production in the rat liver with biliary obstruction does not contribute to promote hepatic injury. | 2008 | Shock | pmid:17885643 |
| Meen O et al. | No case of COX-1-related aspirin resistance found in 289 patients with symptoms of stable CHD remitted for coronary angiography. | 2008 | Scand. J. Clin. Lab. Invest. | pmid:17934975 |
| Zhao S et al. | Predominant basal directional release of thromboxane, but not prostacyclin, by placental trophoblasts from normal and preeclamptic pregnancies. | 2008 | Placenta | pmid:17936899 |
| Heistein LC et al. | Aspirin resistance in children with heart disease at risk for thromboembolism: prevalence and possible mechanisms. | 2008 | Pediatr Cardiol | pmid:17896127 |
| Larson MK et al. | Effects of omega-3 acid ethyl esters and aspirin, alone and in combination, on platelet function in healthy subjects. | 2008 | Thromb. Haemost. | pmid:18841286 |
| Lessa A et al. | The effect of pentoxifylline on the pulmonary response to high tidal volume ventilation in rats. | 2008 | Pulm Pharmacol Ther | pmid:17251044 |
| Aslam R et al. | Lipoproteins inhibit platelet aggregation and arachidonic acid metabolism in experimental hypercholesterolaemia. | 2008 | Clin. Exp. Pharmacol. Physiol. | pmid:18215184 |
| Toscano CD et al. | NMDA-induced seizure intensity is enhanced in COX-2 deficient mice. | 2008 | Neurotoxicology | pmid:18834901 |
| Lee CR et al. | Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study. | 2008 | Clin. Pharmacol. Ther. | pmid:17495879 |
| Awad H et al. | Intracellular and extracellular expression of the major inducible 70kDa heat shock protein in experimental ischemia-reperfusion injury of the spinal cord. | 2008 | Exp. Neurol. | pmid:18511046 |
| Basselin M et al. | Chronic administration of valproic acid reduces brain NMDA signaling via arachidonic acid in unanesthetized rats. | 2008 | Neurochem. Res. | pmid:18461450 |
| Dobaczewski M et al. | Targeting the urine and plasma determinants of thromboxane A2 metabolism in detection of aspirin effectiveness. | 2008 | Blood Coagul. Fibrinolysis | pmid:18600093 |
| Rossoni G et al. | Combined simvastatin-manidipine protect against ischemia-reperfusion injury in isolated hearts from normocholesterolemic rats. | 2008 | Eur. J. Pharmacol. | pmid:18442813 |
| Yan Q et al. | Female ROMK null mice manifest more severe Bartter II phenotype on renal function and higher PGE2 production. | 2008 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:18579648 |
| Gao L et al. | [Effects of supplementing qi and activating blood circulation method on platelet aggregation rate, adhesion rate and thromboxane B2 level in patients with stable angina pectoris and intolerable to aspirin]. | 2008 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:18543479 |
| Patrignani P et al. | Differential association between human prostacyclin receptor polymorphisms and the development of venous thrombosis and intimal hyperplasia: a clinical biomarker study. | 2008 | Pharmacogenet. Genomics | pmid:18551041 |
| Cheuk BL and Cheng SW | Can local secretion of prostaglandin E2, thromboxane B2, and interleukin-6 play a role in ruptured abdominal aortic aneurysm? | 2008 | World J Surg | pmid:17992560 |
| Francois H et al. | A role for the thromboxane receptor in L-NAME hypertension. | 2008 | Am. J. Physiol. Renal Physiol. | pmid:18684890 |
| Guthikonda S et al. | Increased platelet sensitivity among individuals with aspirin resistance - platelet aggregation to submaximal concentration of arachidonic acid predicts response to antiplatelet therapy. | 2008 | Thromb. Haemost. | pmid:18612542 |
| Kaehler S et al. | S-ibuprofen effectively inhibits thromboxane B2 levels and platelet function in an experimental model of lipopolysaccharide-stimulated and non-stimulated whole blood. | 2008 | Pharmacology | pmid:18043009 |
| Elander N et al. | Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18485889 |
| Abdelwhab S and Elshinnawy S | Pulmonary hypertension in chronic renal failure patients. | 2008 | Am. J. Nephrol. | pmid:18635926 |
| Graff J et al. | Significant effects of tipranavir on platelet aggregation and thromboxane B2 formation in vitro and in vivo. | 2008 | J. Antimicrob. Chemother. | pmid:18156609 |
| Delgado-Lista J et al. | Chronic dietary fat intake modifies the postprandial response of hemostatic markers to a single fatty test meal. | 2008 | Am. J. Clin. Nutr. | pmid:18258620 |
| Tanen DA et al. | Comparison of oral aspirin versus topical applied methyl salicylate for platelet inhibition. | 2008 | Ann Pharmacother | pmid:18698012 |
| Nocun M et al. | French maritime pine bark extract Pycnogenol reduces thromboxane generation in blood from diabetic male rats. | 2008 | Biomed. Pharmacother. | pmid:17698319 |
| Park MK et al. | Antiplatelet and antithrombotic activity of indole-3-carbinol in vitro and in vivo. | 2008 | Phytother Res | pmid:17724769 |
| Rao CV et al. | Pharmacokinetic and pharmacodynamic study of NO-donating aspirin in F344 rats. | 2008 | Int. J. Oncol. | pmid:18813794 |
| Rajec J et al. | Biochemical evaluation of the antiplatelet effect of aspirin in patients at different levels of cardiovascular risk. | 2008 | Bratisl Lek Listy | pmid:18814431 |
| Helgason CM et al. | Platelet aggregation and recruitment with aspirin-clopidogrel therapy. | 2008 | Cerebrovasc. Dis. | pmid:18349532 |
| Momen A et al. | Local prostaglandin blockade attenuates muscle mechanoreflex-mediated renal vasoconstriction during muscle stretch in humans. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18326807 |
| Skoglund C et al. | C-reactive protein and C1q regulate platelet adhesion and activation on adsorbed immunoglobulin G and albumin. | 2008 | Immunol. Cell Biol. | pmid:18332893 |
| Menzies D et al. | Effect of aspirin on airway inflammation and pulmonary function in patients with persistent asthma. | 2008 | J. Allergy Clin. Immunol. | pmid:18313127 |
| Geske FJ et al. | AspirinWorks: a new immunologic diagnostic test for monitoring aspirin effect. | 2008 | Mol Diagn Ther | pmid:18288882 |
| Selg E et al. | Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung. | 2008 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:18294831 |
| Basselin M et al. | Chronic carbamazepine administration attenuates dopamine D2-like receptor-initiated signaling via arachidonic acid in rat brain. | 2008 | Neurochem. Res. | pmid:18302021 |
| Signore C et al. | Markers of oxidative stress and systemic vasoconstriction in pregnant women drinking > or =48 g of alcohol per day. | 2008 | Alcohol. Clin. Exp. Res. | pmid:18715278 |
| Roethig HJ et al. | A 12-month, randomized, controlled study to evaluate exposure and cardiovascular risk factors in adult smokers switching from conventional cigarettes to a second-generation electrically heated cigarette smoking system. | 2008 | J Clin Pharmacol | pmid:18319361 |
| Al-Salam Z et al. | The effect of dobutamine on platelet aggregatory function in newborn piglets with hypoxia and reoxygenation. | 2008 | Shock | pmid:18323735 |
| Park JW et al. | 15,16-dihydrotanshinone I, a major component from Salvia miltiorrhiza Bunge (Dansham), inhibits rabbit platelet aggregation by suppressing intracellular calcium mobilization. | 2008 | Arch. Pharm. Res. | pmid:18277607 |
| Schwartz JI et al. | Comparative inhibitory activity of etoricoxib, celecoxib, and diclofenac on COX-2 versus COX-1 in healthy subjects. | 2008 | J Clin Pharmacol | pmid:18434566 |
| Cui J et al. | Cyclooxygenase inhibition attenuates sympathetic responses to muscle stretch in humans. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18441194 |
| Hasan J et al. | Early postnatal ibuprofen and indomethacin effects in suckling and weanling rat kidneys. | 2008 | Prostaglandins Other Lipid Mediat. | pmid:18096423 |
| Karon BS et al. | Aspirin responsiveness in healthy volunteers measured with multiple assay platforms. | 2008 | Clin. Chem. | pmid:18420732 |
| Hinz B et al. | Impact of naproxen sodium at over-the-counter doses on cyclooxygenase isoforms in human volunteers. | 2008 | Int J Clin Pharmacol Ther | pmid:18397691 |
| Bruce EC et al. | Platelet thromboxane A2 secretion in patients with major depression responsive to electroconvulsive therapy. | 2008 | Psychosom Med | pmid:18378867 |
| Wooten JG et al. | Cyclooxygenase expression and prostanoid production in pyloric and duodenal mucosae in dogs after administration of nonsteroidal anti-inflammatory drugs. | 2008 | Am. J. Vet. Res. | pmid:18380576 |
| Eikelboom JW et al. | Incomplete inhibition of thromboxane biosynthesis by acetylsalicylic acid: determinants and effect on cardiovascular risk. | 2008 | Circulation | pmid:18838564 |
| Banting A et al. | Efficacy of oral and parenteral ketoprofen in lactating cows with endotoxin-induced acute mastitis. | 2008 | Vet. Rec. | pmid:18953074 |
| Ruan KH et al. | An active triple-catalytic hybrid enzyme engineered by linking cyclo-oxygenase isoform-1 to prostacyclin synthase that can constantly biosynthesize prostacyclin, the vascular protector. | 2008 | FEBS J. | pmid:19021758 |
| Jiang H et al. | The midnight-noon ebb-flow point selection for 30 cases of acute ischemic cerebrovascular diseases. | 2008 | J Tradit Chin Med | pmid:19004202 |
| Otani Y et al. | Effects of the COX-2 inhibitor FK3311 on ischemia - reperfusion injury in the rat lung. | 2007 May-Jun | J Invest Surg | pmid:17613692 |
| Jiang J et al. | Endothelin-1 blockade prevents COX2 induction and TXA2 production in the fructose hypertensive rat. | 2007 Mar-Apr | Can. J. Physiol. Pharmacol. | pmid:17612651 |
| Csanyi G et al. | Lack of endothelium-derived hyperpolarizing factor (EDHF) up-regulation in endothelial dysfunction in aorta in diabetic rats. | 2007 Jul-Aug | Pharmacol Rep | pmid:17901574 |
| Komers R et al. | Cyclo-oxygenase-2 inhibition attenuates the progression of nephropathy in uninephrectomized diabetic rats. | 2007 Jan-Feb | Clin. Exp. Pharmacol. Physiol. | pmid:17201733 |
| González-Correa JA et al. | Gender differences in the effect of aspirin on retinal ischemia, prostanoid synthesis and nitric oxide production in experimental type 1-like diabetes. | 2007 Aug-Sep | Vascul. Pharmacol. | pmid:17581795 |
| Sood BG et al. | PGE2/TXB2 imbalance in neonatal hypoxemic respiratory failure. | 2007 | Acta Paediatr. | pmid:17376184 |
| Li XM et al. | [Physiological effects of cold and cool Chinese herbal medicine of channel tropism of stomach on rats with stomach-heat syndrome]. | 2007 | Zhongguo Zhong Yao Za Zhi | pmid:17672345 |
| Bogani P et al. | Postprandial anti-inflammatory and antioxidant effects of extra virgin olive oil. | 2007 | Atherosclerosis | pmid:16488419 |
| Sekine S et al. | Lowering systolic blood pressure and increases in vasodilator levels in SHR with oral alpha-linolenic acid administration. | 2007 | J Oleo Sci | pmid:17898500 |