Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Uremia D014511 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypoxia D000860 23 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Authors Title Published Journal PubMed Link
Eizayaga FX et al. Modifications produced by selective inhibitors of cyclooxygenase and ultra low dose aspirin on platelet activity in portal hypertension. 2007 World J. Gastroenterol. pmid:17876871
Fujiwara T et al. Exploratory aspirin resistance trial in healthy Japanese volunteers (J-ART) using platelet aggregation as a measure of thrombogenicity. 2007 Pharmacogenomics J. pmid:17245331
Maree AO et al. Drug insight: aspirin resistance-fact or fashion? 2007 Nat Clin Pract Cardiovasc Med pmid:17330121
Ciabattoni G et al. Determinants of platelet activation in Alzheimer's disease. 2007 Neurobiol. Aging pmid:16442186
De Candia E et al. Defective platelet responsiveness to thrombin and protease-activated receptors agonists in a novel case of gray platelet syndrome: correlation between the platelet defect and the alpha-granule content in the patient and four relatives. 2007 J. Thromb. Haemost. pmid:17137471
Miyamoto A et al. Ibuprofen or ozagrel increases NO release and l-nitro arginine induces TXA(2) release from cultured porcine basilar arterial endothelial cells. 2007 Vascul. Pharmacol. pmid:17113355
Kim YJ and Chung HY Antioxidative and anti-inflammatory actions of docosahexaenoic acid and eicosapentaenoic acid in renal epithelial cells and macrophages. 2007 J Med Food pmid:17651056
Rossoni G et al. Positive interaction of the novel beta2-agonist carmoterol and tiotropium bromide in the control of airway changes induced by different challenges in guinea-pigs. 2007 Pulm Pharmacol Ther pmid:16533614
Jeng JH et al. Antiplatelet effect of sanguinarine is correlated to calcium mobilization, thromboxane and cAMP production. 2007 Atherosclerosis pmid:16797553
Ansari HR et al. Involvement of COX-1 in A3 adenosine receptor-mediated contraction through endothelium in mice aorta. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:17921329
Ivandic BT et al. Determination of aspirin responsiveness by use of whole blood platelet aggregometry. 2007 Clin. Chem. pmid:17332149
Calzada C et al. In vitro glycoxidized low-density lipoproteins and low-density lipoproteins isolated from type 2 diabetic patients activate platelets via p38 mitogen-activated protein kinase. 2007 J. Clin. Endocrinol. Metab. pmid:17341567
Eligini S et al. Paracrine up-regulation of monocyte cyclooxygenase-2 by platelets: role of transforming growth factor-beta1. 2007 Cardiovasc. Res. pmid:17250815
Sood BG et al. PGE2/TXB2 imbalance in neonatal hypoxemic respiratory failure. 2007 Acta Paediatr. pmid:17376184
Kalaitzis C et al. Role of eicosanoids of the contralateral kidney in maintenance of two-kidney, one-clip renovascular hypertension in rats. 2007 Scand. J. Urol. Nephrol. pmid:17853043
Coppinger JA et al. Moderation of the platelet releasate response by aspirin. 2007 Blood pmid:17303692
Graff J et al. Effects of parecoxib and dipyrone on platelet aggregation in patients undergoing meniscectomy: a double-blind, randomized, parallel-group study. 2007 Clin Ther pmid:17577465
Crescente M et al. Gallic acid, a dietary polyphenolic component, blunts the inhibition of platelet COX-1 by aspirin: preliminary in-vitro findings. 2007 Thromb. Haemost. pmid:17549313
Undas A et al. Lack of aspirin-induced decrease in thrombin formation in subjects resistant to aspirin. 2007 Thromb. Haemost. pmid:17549314
Chakroun T et al. Screening for aspirin resistance in stable coronary artery patients by three different tests. 2007 Thromb. Res. pmid:17553552
Pucsok JM et al. Effect of exercise on levels of cyclo-oxygenase mediators in exhaled breath condensate in elite athletes. 2007 J Sports Med Phys Fitness pmid:17557063
Hohlfeld T et al. Variable platelet response to aspirin in patients with ischemic stroke. 2007 Cerebrovasc. Dis. pmid:17519543
Allais G et al. Naproxen sodium in short-term prophylaxis of pure menstrual migraine: pathophysiological and clinical considerations. 2007 Neurol. Sci. pmid:17508177
Wong PC et al. Platelet aggregometry and receptor binding to predict the magnitude of antithrombotic and bleeding time effects of clopidogrel in rabbits. 2007 J. Cardiovasc. Pharmacol. pmid:17513951
Hsiao G et al. Characterization of a novel and potent collagen antagonist, caffeic acid phenethyl ester, in human platelets: in vitro and in vivo studies. 2007 Cardiovasc. Res. pmid:17560560
Basselin M et al. Flurbiprofen, a cyclooxygenase inhibitor, reduces the brain arachidonic acid signal in response to the cholinergic muscarinic agonist, arecoline, in awake rats. 2007 Neurochem. Res. pmid:17562170
Aras-Lopéz R et al. Dexamethasone decreases contraction to electrical field stimulation in mesenteric arteries from spontaneously hypertensive rats through decreases in thromboxane A2 release. 2007 J. Pharmacol. Exp. Ther. pmid:17562850
Zheng BH et al. [The effect of inhaled nitric oxide on endothelium-derived angiokinetic factors in patients with acute high altitude disease]. 2007 Zhonghua Jie He He Hu Xi Za Zhi pmid:17445476
Suzuki A et al. Ferulic acid restores endothelium-dependent vasodilation in aortas of spontaneously hypertensive rats. 2007 Am. J. Hypertens. pmid:17485012
Basselin M et al. Chronic lithium administration attenuates up-regulated brain arachidonic acid metabolism in a rat model of neuroinflammation. 2007 J. Neurochem. pmid:17488274
Gracia-Sancho J et al. Enhanced vasoconstrictor prostanoid production by sinusoidal endothelial cells increases portal perfusion pressure in cirrhotic rat livers. 2007 J. Hepatol. pmid:17459512
Yu XM et al. [Relations of platelet phospholipid fatty acids to thrombotic risk factors in middle-aged and geriatric patients with hyperlipidemia]. 2007 Zhonghua Yi Xue Za Zhi pmid:17418017
Maree AO and Fitzgerald DJ Variable platelet response to aspirin and clopidogrel in atherothrombotic disease. 2007 Circulation pmid:17452618
Aïd S and Bosetti F Gene expression of cyclooxygenase-1 and Ca(2+)-independent phospholipase A(2) is altered in rat hippocampus during normal aging. 2007 Brain Res. Bull. pmid:17499644
Faraday N et al. Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1. 2007 Circulation pmid:17470694
Luceri C et al. p-Coumaric acid, a common dietary phenol, inhibits platelet activity in vitro and in vivo. 2007 Br. J. Nutr. pmid:17313706
Basselin M et al. Chronic carbamazepine administration reduces N-methyl-D-aspartate receptor-initiated signaling via arachidonic acid in rat brain. 2007 Biol. Psychiatry pmid:17628508
Bray PF et al. Heritability of platelet function in families with premature coronary artery disease. 2007 J. Thromb. Haemost. pmid:17663734
Saeed SA et al. Dual inhibition of cyclooxygenase and lipoxygenase by human haptoglobin: its polymorphism and relation to hemoglobin binding. 2007 Biochem. Biophys. Res. Commun. pmid:17198677
Chang MC et al. Hydroxychavicol, a novel betel leaf component, inhibits platelet aggregation by suppression of cyclooxygenase, thromboxane production and calcium mobilization. 2007 Br. J. Pharmacol. pmid:17641677
Liu J et al. FcRgamma-chain signals in the absence of glycoprotein VI. 2007 J. Thromb. Haemost. pmid:17010148
Li XM et al. [Physiological effects of cold and cool Chinese herbal medicine of channel tropism of stomach on rats with stomach-heat syndrome]. 2007 Zhongguo Zhong Yao Za Zhi pmid:17672345
Park JB Caffedymine from cocoa has COX inhibitory activity suppressing the expression of a platelet activation marker, P-selectin. 2007 J. Agric. Food Chem. pmid:17319684
Guthikonda S et al. Reticulated platelets and uninhibited COX-1 and COX-2 decrease the antiplatelet effects of aspirin. 2007 J. Thromb. Haemost. pmid:17319904
Rohatagi S et al. Predictive population pharmacokinetic/pharmacodynamic model for a novel COX-2 inhibitor. 2007 J Clin Pharmacol pmid:17322148
González-Correa JA et al. Differences in the influence of the interaction between acetylsalicylic acid and salicylic acid on platelet function in whole blood and isolated platelets: influence of neutrophils. 2007 Pharmacol. Res. pmid:17644353
Gendron ME and Thorin E A change in the redox environment and thromboxane A2 production precede endothelial dysfunction in mice. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:17644574
Weber AA et al. Effects of selective cyclooxygenase isoform inhibition on systemic prostacyclin synthesis and on platelet function at rest and after exercise in healthy volunteers. 2007 Platelets pmid:17654308
Sun LQ et al. [Relationship between syndrome differentiation of traditional Chinese medicine and vascular endothelial function in patients with diabetic arterial occlusion of lower extremities]. 2007 Zhong Xi Yi Jie He Xue Bao pmid:17997934
Marvin CC et al. Synthesis of thromboxane B2 via ketalization/ring-closing metathesis. 2007 Org. Lett. pmid:18047355
Wang Z et al. Changes of vasoactive polypeptides during postoperative hypertensive crisis in patients with hypertensive intracerebral hemorrhage. 2007 Chin. Med. J. pmid:18167188
Silvanto M et al. Effect of 3 g of intravenous paracetamol on post-operative analgesia, platelet function and liver enzymes in patients undergoing tonsillectomy under local anaesthesia. 2007 Acta Anaesthesiol Scand pmid:17711562
Xing X and Li H Isolated liver perfusion for regional chemotherapy in rats. 2007 HBPD INT pmid:17690035
Schwartz JI et al. Effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs on urinary sodium excretion, blood pressure, and other renal function indicators in elderly subjects consuming a controlled sodium diet. 2007 J Clin Pharmacol pmid:17925592
Capone ML et al. Human pharmacology of naproxen sodium. 2007 J. Pharmacol. Exp. Ther. pmid:17473175
Maksimova MIu et al. [Hemorheology and homeostasis in the most acute stage of lacunar stroke]. 2007 Zh Nevrol Psikhiatr Im S S Korsakova pmid:18427452
Yousefipour Z et al. Ciglitazone, a peroxisome proliferator-activated receptor gamma inducer, ameliorates renal preglomerular production and activity of angiotensin II and thromboxane A2 in glycerol-induced acute renal failure. 2007 J. Pharmacol. Exp. Ther. pmid:17494862
Holma R et al. Prophylactic potential of montelukast against mild colitis induced by dextran sulphate sodium in rats. 2007 J. Physiol. Pharmacol. pmid:17928642
Bogani P et al. Postprandial anti-inflammatory and antioxidant effects of extra virgin olive oil. 2007 Atherosclerosis pmid:16488419
Vidal C et al. Licofelone, a balanced inhibitor of cyclooxygenase and 5-lipoxygenase, reduces inflammation in a rabbit model of atherosclerosis. 2007 J. Pharmacol. Exp. Ther. pmid:17015640
Sekine S et al. Lowering systolic blood pressure and increases in vasodilator levels in SHR with oral alpha-linolenic acid administration. 2007 J Oleo Sci pmid:17898500
Dawood MY and Khan-Dawood FS Differential suppression of menstrual fluid prostaglandin F2a, prostaglandin E2, 6-keto prostaglandin F1a and thromboxane B2 by suprofen in women with primary dysmenorrhea. 2007 Prostaglandins Other Lipid Mediat. pmid:17259081
Jin UH et al. Inhibitory effect of Panax notoginseng on nitric oxide synthase, cyclo-oxygenase-2 and neutrophil functions. 2007 Phytother Res pmid:17128437
Yang YY et al. Effect of chronic CB1 cannabinoid receptor antagonism on livers of rats with biliary cirrhosis. 2007 Clin. Sci. pmid:17176248
Shemesh E et al. Symptoms of posttraumatic stress disorder in patients who have had a myocardial infarction. 2006 May-Jun Psychosomatics pmid:16684940
Tuominen OM et al. Effects of bisphosphonates on prostaglandin E2 and thromboxane B2 production in human whole blood and monocytes stimulated by lipopolysaccharide and A23187. 2006 Jul-Aug Methods Find Exp Clin Pharmacol pmid:16894405
Wang LH et al. Effect of heparin on activation of platelet function in patients during radiofrequency catheter ablation. 2006 Jan-Feb Clin. Exp. Pharmacol. Physiol. pmid:16445701
Wynn RL and Cook J Does ibuprofen block the cardioprotective effects of aspirin in dental patients? 2006 Jan-Feb Gen Dent pmid:16494111
Sciulli MG et al. Heterogeneity in the suppression of platelet cyclooxygenase-1 activity by aspirin in coronary heart disease. 2006 Clin. Pharmacol. Ther. pmid:16890573
Shi T et al. Anti-beta2-glycoprotein I antibodies in complex with beta2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V. 2006 Arthritis Rheum. pmid:16868978
Ramamurthy S et al. Characterization of thromboxane A2 receptor signaling in developing rat oligodendrocytes: nuclear receptor localization and stimulation of myelin basic protein expression. 2006 J. Neurosci. Res. pmid:16998891
Zhou Y et al. Increased expression of cyclooxygenase-2 mediates enhanced contraction to endothelin ETA receptor stimulation in endothelial nitric oxide synthase knockout mice. 2006 Circ. Res. pmid:16645140
Karkabounas S et al. Anticarcinogenic and antiplatelet effects of carvacrol. 2006 Exp. Oncol. pmid:16837902
Wilder-Smith CH et al. Dose-effect comparisons of the CINOD AZD3582 and naproxen on upper gastrointestinal tract mucosal injury in healthy subjects. 2006 Scand. J. Gastroenterol. pmid:16497612
Brenneis C et al. Inhibition of prostaglandin E2 synthesis by SC-560 is independent of cyclooxygenase 1 inhibition. 2006 FASEB J. pmid:16816110
Baltzer WI et al. Measurement of urinary 11-dehydro-thromboxane B2 excretion in dogs with gastric dilatation-volvulus. 2006 Am. J. Vet. Res. pmid:16426215
Chiu HF et al. Mechanisms involved in the antiplatelet effect of C-phycocyanin. 2006 Br. J. Nutr. pmid:16469164
Rossoni G et al. Nitric oxide and prostacyclin pathways: an integrated mechanism that limits myocardial infarction progression in anaesthetized rats. 2006 Pharmacol. Res. pmid:16488624
Lepäntalo A et al. Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients. 2006 Thromb. Haemost. pmid:16493486
Kurosawa S et al. Effects of ulinastatin on pulmonary artery pressure during abdominal aortic aneurysmectomy. 2006 J Clin Anesth pmid:16517327
Ibrahim S et al. Transfer of very low density lipoprotein-associated phospholipids to activated human platelets. 2006 J. Lipid Res. pmid:16293890
Yin M et al. [Experimental study of effects of cyclooxygenase-2 inhibitor on apoptosis of hypoxic myocardial cells in vitro]. 2006 Zhongguo Wei Zhong Bing Ji Jiu Yi Xue pmid:16647015
Ahmad S et al. Cardamonin, inhibits pro-inflammatory mediators in activated RAW 264.7 cells and whole blood. 2006 Eur. J. Pharmacol. pmid:16650843
Fontana P et al. Biological effects of aspirin and clopidogrel in a randomized cross-over study in 96 healthy volunteers. 2006 J. Thromb. Haemost. pmid:16634751
Markuszewski L et al. Reduced blood platelet sensitivity to aspirin in coronary artery disease: are dyslipidaemia and inflammatory states possible factors predisposing to sub-optimal platelet response to aspirin? 2006 Basic Clin. Pharmacol. Toxicol. pmid:16635110
Cheung PY et al. Platelet dysfunction in asphyxiated newborn piglets resuscitated with 21% and 100% oxygen. 2006 Pediatr. Res. pmid:16627873
Laleman W et al. A stable model of cirrhotic portal hypertension in the rat: thioacetamide revisited. 2006 Eur. J. Clin. Invest. pmid:16620286
Zhao Y et al. Effect of a Chinese herbal formula, Shi-Bi-Lin, on an experimental model of allergic rhinitis. 2006 Ann. Allergy Asthma Immunol. pmid:16802773
Lee KS et al. Antiplatelet activity of [5-(2-methoxy-5-chlorophenyl)furan-2-ylcarbonyl]guanidine (KR-32570), a novel sodium/hydrogen exchanger-1 and its mechanism of action. 2006 Arch. Pharm. Res. pmid:16756082
Peck OM et al. The phosphatidylinositol 3 kinase pathway regulates tolerance to lipopolysaccharide and priming responses to Staphylococcus aureus and lipopolysaccharide. 2006 Shock pmid:16783195
Frelinger AL et al. Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance. 2006 Circulation pmid:16785341
Cox D et al. Effect of enteric coating on antiplatelet activity of low-dose aspirin in healthy volunteers. 2006 Stroke pmid:16794200
Munsterhjelm E et al. Influence on platelet aggregation of i.v. parecoxib and acetaminophen in healthy volunteers. 2006 Br J Anaesth pmid:16698862
Zhang JY et al. [Study on therapeutic effects of series of muskone on myocardial infarction canines]. 2006 Zhongguo Zhong Yao Za Zhi pmid:17225541
Basili S et al. Insulin resistance as a determinant of platelet activation in obese women. 2006 J. Am. Coll. Cardiol. pmid:17174194
Hrushka NH et al. [Effect of thromboxane B2 on morphological features of apoptosis in cultured rat hepatocytes exposed to hepatotropic substances]. 2006 Fiziol Zh pmid:17176837
Niemi TT et al. The effect of N-acetylcysteine on blood coagulation and platelet function in patients undergoing open repair of abdominal aortic aneurysm. 2006 Blood Coagul. Fibrinolysis pmid:16607076
Chiang N and Serhan CN New mechanism for an old drug: aspirin triggers anti-inflammatory lipid mediators with gender implications. 2006 Compr Ther pmid:17435267
Chiang N et al. Aspirin has a gender-dependent impact on antiinflammatory 15-epi-lipoxin A4 formation: a randomized human trial. 2006 Arterioscler. Thromb. Vasc. Biol. pmid:16293793
Wolfram RM et al. Salivary isoprostanes indicate increased oxidation injury in periodontitis with additional tobacco abuse. 2006 Biofactors pmid:17264390