Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Uremia D014511 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypoxia D000860 23 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Smith EF and Lefer AM Stabilization of cardiac lysosomal and cellular membranes in protection of ischemic myocardium due to coronary occlusion:efficacy of the nonsteroidal anti-inflammatory agent, naproxen. 1981 Am. Heart J. pmid:7211667
Shaw JO et al. Activation of rabbit platelet phospholipase and thromboxane synthesis by 1-O-hexadecyl/octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (platelet activating factor). 1981 Biochim. Biophys. Acta pmid:7213765
Okamatsu S et al. Effect of calcium channel blockers on arachidonate-induced sudden death in rabbits. 1981 Proc. Soc. Exp. Biol. Med. pmid:6261265
Rao GH et al. Modification of human platelet response to sodium arachidonate by membrane modulation. 1981 Prostaglandins Med pmid:6261286
di Minno G et al. Effects of any epoxymethano stable analogue of prostaglandin endoperoxides (U-46619) on human platelets. 1981 Thromb. Haemost. pmid:6266066
Handler JS Vasopressin-prostaglandin interactions in the regulation of epithelial cell permeability to water. 1981 Kidney Int. pmid:6267350
Best LC et al. Strontium ions induce production of thromboxane B2 and secretion of 5-hydroxytryptamine in washed human platelets. 1981 Biochem. Pharmacol. pmid:6268118
Ylikorkala O et al. Effect of cytostatics on prostaglandin F2 alpha prostacyclin, and thromboxane in patients with gynecologic malignancies. 1981 Obstet Gynecol pmid:7024882
Siess W et al. Stimulated platelet aggregation, thromboxane B2 formation and platelet sensitivity to prostacyclin - a critical evaluation. 1981 Thromb. Haemost. pmid:7025338
Webb PJ et al. Do prostacyclin and thromboxane play a role in endotoxic shock? 1981 Br J Surg pmid:7025959
Parks WM et al. Comparative effect of ibuprofen on endothelial and platelet prostaglandin synthesis. 1981 J. Pharmacol. Exp. Ther. pmid:7026767
Roy AC et al. Effect of intravenous infusion of OKY-1581 (sodium-(E)-3-[4-(3-pyridylmethyl)phenyl] -2-methylacrylate) on circulatory thromboxane A2 and prostacyclin levels in anaesthetized baboon. 1981 Prostaglandins Med pmid:7029585
Roselló J et al. Quantitative profiling of the metabolic cascade of arachidonic acid by capillary gas chromatography mass spectrometry. 1981 Biomed. Mass Spectrom. pmid:7236862
Stuart MJ Effect of endotoxin on arachidonic acid release and thromboxane B2 production by human platelets. 1981 Am. J. Hematol. pmid:7030066
Cook JA et al. Sensitization of essential fatty acid-deficient rats to endotoxin by arachidonate pretreatment: role of thromboxane A2. 1981 Circ. Shock pmid:7237685
Lorenz R et al. Effects of very low versus standard dose acetyl salicylic acid, dipyridamole and sulfinpyrazone on platelet function and thromboxane formation in man. 1981 Eur. J. Pharmacol. pmid:7238575
Polley MJ et al. Human complement in the arachidonic acid transformation pathway in platelets. 1981 J. Exp. Med. pmid:7241047
Greenberg S et al. Pulmonary vascular smooth muscle function in porcine splanchnic arterial occlusion shock. 1981 Am. J. Physiol. pmid:7246787
Townsend ER et al. Preservation of platelets during extracorporeal circulation in sheep. A comparison between aspirin and sulfinpyrazone. 1981 Circ. Res. pmid:7249281
McCann DS et al. Radioimmunoassay for plasma thromboxane B2. 1981 Clin. Chem. pmid:7273401
Utsunomiya T et al. Maintenance of cardiodynamics with aspirin during abdominal aortic aneurysmectomy (AAA). 1981 Ann. Surg. pmid:6117260
Mahoney DA et al. Urinary thromboxane B2 on allograft rejection. 1981 Lancet pmid:6118500
Allen JB et al. Irradiation decreases vascular prostacyclin formation with no concomitant effect on platelet thromboxane production. 1981 Lancet pmid:6118629
Stenson WF et al. Metabolism of exogenous arachidonic acid by murine macrophage-like tumor cell lines. 1981 Prostaglandins pmid:6803301
Kelly KL and Laychock SG Prostaglandin synthesis and metabolism in isolated pancreatic islets of the rat. 1981 Prostaglandins pmid:6803305
Zijlstra FJ and Vincent JE Contractile characteristics of the rat stomach strip and the rabbit aorta and mesenteric artery. 1981 J Pharmacol Methods pmid:7265989
Gilani SH and Persaud TV Embryopathic effects of thromboxane B2 in the chick. 1981 Prostaglandins Med pmid:7267828
Anderson CB et al. Thromboxane-B2 and renovascular resistance during hypothermic pulsatile perfusion. 1981 Transplant. Proc. pmid:7268892
Malemud CJ et al. Prostaglandin biosynthesis by lapine articular chondrocytes in culture. 1981 Biochim. Biophys. Acta pmid:6894251
Ohnishi H et al. Effects of trapidil on thromboxane A2-induced aggregation of platelets, ischemic changes in heart and biosynthesis of thromboxane A2. 1981 Prostaglandins Med pmid:6894333
Coker SJ et al. Thromboxane and prostacyclin release from ischaemic myocardium in relation to arrhythmias. 1981 Nature pmid:6894485
Bishai I and Coceani F Transformations of prostaglandin H2 in the cat brain. 1981 Biochim. Biophys. Acta pmid:6894549
Drake TS et al. Peritoneal fluid thromboxane B2 and 6-keto-prostaglandin F1 alpha in endometriosis. 1981 Am. J. Obstet. Gynecol. pmid:6894667
Halushka PV et al. Protective effects of aspirin in endotoxic shock. 1981 J. Pharmacol. Exp. Ther. pmid:6894770
Feuerstein N et al. Leukotrienes C4 and D4 induce prostaglandin and thromboxane release from rat peritoneal macrophages. 1981 Br. J. Pharmacol. pmid:6894882
Ylikorkala O and Viinikka L Prostacyclin, thromboxane, and prostaglandin F2 alpha in maternal plasma during breast-feeding. 1981 Am. J. Obstet. Gynecol. pmid:7011034
Karmazyn M et al. Comparative effects of acetylsalicylic acid (ASA) and sulfinpyrazone on isoproterenol-induced heart damage. 1981 J. Pharmacol. Exp. Ther. pmid:6894943
Morrison AR and Benabe JE Prostaglandins in vascular tone in experimental obstructive nephropathy. 1981 Kidney Int. pmid:6894950
Seitz M et al. The influence of synovial fluid from patients with rheumatoid arthritis on the proliferation of peripheral blood lymphocytes and the prostanoid release from monocytes. 1981 Agents Actions pmid:7340450
Prancan A et al. Platelet thromboxane production during endotoxin shock. 1981 Agents Actions pmid:7340458
Hwang DH Characteristics of the aggregation of platelets and the formation of prostaglandins (PGs) in rat. 1981 Prog. Lipid Res. pmid:7342108
Greenwald JE et al. Argentation thin layer chromatography of arachidonic acid metabolites isolated from human platelets. 1981 Prostaglandins pmid:7208953
Morrison AR et al. Thromboxane A2 is the major arachidonic acid metabolite of human cortical hydronephrotic tissue. 1981 Prostaglandins pmid:6894498
She HS et al. Metabolism of prostaglandin endoperoxide by microsomes from cat lung. 1981 Prostaglandins pmid:6894797
Halushka PV et al. Increased platelet thromboxane synthesis in diabetes mellitus. 1981 J. Lab. Clin. Med. pmid:7452084
Honn KV and Meyer J Thromboxanes and prostacyclin: positive and negative modulators of tumor growth. 1981 Biochem. Biophys. Res. Commun. pmid:6274330
Shaw JO Effects of extracellular Ca2+ and the intracellular Ca2+ antagonist 8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate on rabbit platelet conversion of arachidonic acid into thromboxane. 1981 Prostaglandins pmid:6789402
Ingerman-Wojenski C et al. Prostacyclin production in rabbit arteries in situ: inhibition by arachidonic acid-induced endothelial cell damage or by low-dose aspirin. 1981 Prostaglandins pmid:6789404
Agradi E et al. Dietary linoleic acid, accumulation of arachidonic acid in tissue lipids and production of TXB2 and PGI2 in the cardiovascular system. 1981 Prog. Lipid Res. pmid:7043483
Wilhelm TE et al. Selective inhibitors of platelet lipoxygenase: 4,7,10,13-eicosatetraynoic acid and 5,8,11,14-henicosatetraynoic acid. 1981 Prostaglandins pmid:6784191