| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Airway Obstruction | D000402 | 13 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Graft Occlusion, Vascular | D006083 | 11 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Arruzazabala ML et al. | Effects of d-003, a new substance purified from sugar cane wax, on platelet aggregation and plasma levels of arachidonic acid metabolites in healthy volunteers. | 2004 | Int J Clin Pharmacol Res | pmid:15689052 |
| Lam AN et al. | Effect of red clover isoflavones on cox-2 activity in murine and human monocyte/macrophage cells. | 2004 | Nutr Cancer | pmid:15456640 |
| Xu L et al. | [Effects of effective component from "qing kai ling" on endothelial cell of microvessel in MCAO rats]. | 2004 | Zhong Yao Cai | pmid:15376390 |
| Perneby C et al. | Prothrombotic responses to exercise are little influenced by clopidogrel treatment. | 2004 | Thromb. Res. | pmid:15381386 |
| Hennekens CH et al. | Terms and conditions: semantic complexity and aspirin resistance. | 2004 | Circulation | pmid:15381661 |
| Zhao GR et al. | [Clinical study on relationship between sluggishness of lung-defensive qi and levels of vasoactive intestinal polypeptide and thromboxane B2]. | 2004 | Zhong Xi Yi Jie He Xue Bao | pmid:15383251 |
| Fiorucci S et al. | Co-administration of nitric oxide-aspirin (NCX-4016) and aspirin prevents platelet and monocyte activation and protects against gastric damage induced by aspirin in humans. | 2004 | J. Am. Coll. Cardiol. | pmid:15358033 |
| Van Ryn J et al. | Meloxicam does not affect the antiplatelet effect of aspirin in healthy male and female volunteers. | 2004 | J Clin Pharmacol | pmid:15199082 |
| Aikawa K et al. | Effects of antioxidants on coronary microvascular spasm induced by epicardial coronary artery endothelial injury in pigs. | 2004 | Coron. Artery Dis. | pmid:15201617 |
| Lorenzoni R et al. | Short-term prevention of thromboembolic complications in patients with atrial fibrillation with aspirin plus clopidogrel: the Clopidogrel-Aspirin Atrial Fibrillation (CLAAF) pilot study. | 2004 | Am. Heart J. | pmid:15215815 |
| Korkushko OV et al. | [Some mechanisms of the development of endothelial disfunction in aging]. | 2004 | Fiziol Zh | pmid:15174205 |
| Kawano T et al. | Acetaldehyde induces histamine release from human airway mast cells to cause bronchoconstriction. | 2004 | Int. Arch. Allergy Immunol. | pmid:15178893 |
| Ishitsuka Y et al. | Involvement of thromboxane A2 (TXA2) in the early stages of oleic acid-induced lung injury and the preventive effect of ozagrel, a TXA2 synthase inhibitor, in guinea-pigs. | 2004 | J. Pharm. Pharmacol. | pmid:15099446 |
| Dinev D and Andonova M | The effect of general anesthesia and abdominal surgery upon plasma thromboxane B concentrations in horses. | 2004 | Vet Anaesth Analg | pmid:15053753 |
| Menzies-Gow NJ et al. | Endotoxin-induced digital vasoconstriction in horses: associated changes in plasma concentrations of vasoconstrictor mediators. | 2004 | Equine Vet. J. | pmid:15147137 |
| Ghuysen A et al. | Effect of BM-573 [N-terbutyl-N'-[2-(4'-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a dual thromboxane synthase inhibitor and thromboxane receptor antagonist, in a porcine model of acute pulmonary embolism. | 2004 | J. Pharmacol. Exp. Ther. | pmid:15121765 |
| Berrougui H et al. | Argan (Argania spinosa) oil lowers blood pressure and improves endothelial dysfunction in spontaneously hypertensive rats. | 2004 | Br. J. Nutr. | pmid:15613254 |
| Fan JG et al. | [Dynamic changes of plasma levels of prostacycline and thromboxane A2 and their correlation with the severity of hepatic injury in rats with nonalcoholic fatty liver disease]. | 2004 | Zhonghua Gan Zang Bing Za Zhi | pmid:15623379 |
| Vega-Ostertag M et al. | Intracellular events in platelet activation induced by antiphospholipid antibodies in the presence of low doses of thrombin. | 2004 | Arthritis Rheum. | pmid:15457460 |
| Noverr MC and Huffnagle GB | Regulation of Candida albicans morphogenesis by fatty acid metabolites. | 2004 | Infect. Immun. | pmid:15501745 |
| Rocca B et al. | Modulation of the expression and activity of cyclooxygenases in normal and accelerated erythropoiesis. | 2004 | Exp. Hematol. | pmid:15504548 |
| Chou DS et al. | Low concentration of oxidized low density lipoprotein suppresses platelet reactivity in vitro: an intracellular study. | 2004 | Lipids | pmid:15506238 |
| Kawata K et al. | The effects of a selective cyclooxygenase-2 inhibitor on small bowel ischemia-reperfusion injury. | 2003 Nov-Dec | Hepatogastroenterology | pmid:14696445 |
| Tuleja E et al. | Effects of cyclooxygenases inhibitors on vasoactive prostanoids and thrombin generation at the site of microvascular injury in healthy men. | 2003 | Arterioscler. Thromb. Vasc. Biol. | pmid:12730088 |
| Leese PT et al. | The COX-2 selective inhibitor, valdecoxib, does not impair platelet function in the elderly: results of a randomized controlled trial. | 2003 | J Clin Pharmacol | pmid:12751271 |
| Lang I et al. | Heterogeneity of microvascular endothelial cells isolated from human term placenta and macrovascular umbilical vein endothelial cells. | 2003 | Eur. J. Cell Biol. | pmid:12751902 |
| Molina V et al. | Synergistic effect of D-003 and aspirin on experimental thrombosis models. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12711246 |
| ChavarrÃa ME et al. | Prostacyclin/thromboxane early changes in pregnancies that are complicated by preeclampsia. | 2003 | Am. J. Obstet. Gynecol. | pmid:12712098 |
| Dogné JM et al. | Pharmacological evaluation of the novel thromboxane modulator BM-567 (I/II). Effects of BM-567 on platelet function. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12538090 |
| Tanaka S et al. | High dose of inhaled fluticasone reduces high levels of urinary leukotriene E4 in the early morning in mild and moderate nocturnal asthma. | 2003 | Chest | pmid:14605047 |
| Pestel S et al. | Inhibition of prostaglandin D2 clearance in rat hepatocytes by the thromboxane receptor antagonists daltroban and ifetroban and the thromboxane synthase inhibitor furegrelate. | 2003 | Biochem. Pharmacol. | pmid:12906929 |
| De La Cruz P et al. | Effects of clopidogrel and ticlopidine on experimental diabetic ischemic retinopathy in rats. | 2003 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:12595963 |
| Uchida M et al. | Changes in cerebral microcirculation during and after abdominal aortic cross-clamping in rabbits: the role of thromboxane A2 receptor. | 2003 | Anesth. Analg. | pmid:12598238 |
| Zaitsu M et al. | Thromboxane synthesis is increased by upregulation of cytosolic phospholipase A2 and cyclooxygenase-2 in peripheral polymorphonuclear leukocytes during bacterial infection in childhood. | 2003 | Am. J. Hematol. | pmid:12555215 |
| Eatman D et al. | Influences of prostanoids and nitric oxide on post-suspension hypotension in female Sprague-Dawley rats. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12591003 |
| Patel YM et al. | Evidence for a role for Galphai1 in mediating weak agonist-induced platelet aggregation in human platelets: reduced Galphai1 expression and defective Gi signaling in the platelets of a patient with a chronic bleeding disorder. | 2003 | Blood | pmid:12609843 |
| Hausman N et al. | Antenatal administration of celecoxib, a selective cyclooxygenase (COX)-2 inhibitor, appears to improve placental perfusion in the pregnant rabbit. | 2003 | Prostaglandins Other Lipid Mediat. | pmid:12611495 |
| Basta M et al. | F(ab)'2-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins. | 2003 | Nat. Med. | pmid:12612546 |
| Fiorucci S et al. | Gastrointestinal safety of NO-aspirin (NCX-4016) in healthy human volunteers: a proof of concept endoscopic study. | 2003 | Gastroenterology | pmid:12612897 |
| Vigorita MG et al. | Chiral 3,3'-(1,2-ethanediyl)-bis[2-(3,4-dimethoxyphenyl)-4-thiazolidinones] with anti-inflammatory activity. Part 11: evaluation of COX-2 selectivity and modelling. | 2003 | Bioorg. Med. Chem. | pmid:12614885 |
| Reid G et al. | The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. | 2003 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12835412 |
| Vass G et al. | Comparison of nasal and oral inhalation during exhaled breath condensate collection. | 2003 | Am. J. Respir. Crit. Care Med. | pmid:12493648 |
| Bosetti F et al. | Valproic acid down-regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase-1 and -2 in rat brain. | 2003 | J. Neurochem. | pmid:12694395 |
| Gama de Abreu M et al. | One-lung ventilation with high tidal volumes and zero positive end-expiratory pressure is injurious in the isolated rabbit lung model. | 2003 | Anesth. Analg. | pmid:12505956 |
| Szebeni J et al. | Complement activation during hemorrhagic shock and resuscitation in swine. | 2003 | Shock | pmid:14501949 |
| Tanaka Y et al. | Effects of exercise on platelet and aortic functions in aged rats. | 2003 | Acta Physiol. Scand. | pmid:14510779 |
| Vani G et al. | Histone H1 modulates immune status in experimental breast cancer. | 2003 | Chemotherapy | pmid:14504437 |
| Sidhu P et al. | Tissue chamber model of acute inflammation in farm animal species. | 2003 | Res. Vet. Sci. | pmid:12507568 |
| Xia Z et al. | Antioxidant therapy with Salvia miltiorrhiza decreases plasma endothelin-1 and thromboxane B2 after cardiopulmonary bypass in patients with congenital heart disease. | 2003 | J. Thorac. Cardiovasc. Surg. | pmid:14666012 |
| Rossoni G et al. | Nitric oxide-releasing aspirin inhibits vasoconstriction in perfused tail artery of normotensive and spontaneously hypertensive rats. | 2003 | Eur. J. Pharmacol. | pmid:14512099 |
| Wolfram R et al. | Daily prickly pear consumption improves platelet function. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12878452 |
| Yokoyama Y et al. | Role of thromboxane in producing portal hypertension following trauma-hemorrhage. | 2003 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:14613921 |
| Yu CC and Lai YL | Chronic hypoxia attenuates ischemia-reperfusion-induced increase in pulmonary vascular resistance. | 2003 | Life Sci. | pmid:12927588 |
| Zhuang HP et al. | [Effect of aspirin combined with perindopril on prostacyclin, thromboxone A2, and norepinephrine in the blood of arteriosclerosis rabbit models and the cardiac function]. | 2003 | Hunan Yi Ke Da Xue Xue Bao | pmid:12934393 |
| Yi H et al. | [Protective effect of selective cyclooxygenase-2 inhibitor on alcohol-induced liver injury in rats]. | 2003 | Zhonghua Gan Zang Bing Za Zhi | pmid:14636441 |
| Kankuri E et al. | Effects of phenacetin and its metabolite p-phenetidine on COX-1 and COX-2 activities and expression in vitro. | 2003 | Thromb. Res. | pmid:14592552 |
| Heller AR et al. | Clusterin protects the lung from leukocyte-induced injury. | 2003 | Shock | pmid:12865662 |
| Zhang C et al. | Inflammation is involved in the organ damage induced by sinoaortic denervation in rats. | 2003 | J. Hypertens. | pmid:14597858 |
| Wang ZF et al. | The role of inflammatory mediators in severe acute pancreatitis and regulation of glucocorticoids. | 2003 | HBPD INT | pmid:14599960 |
| Eder K et al. | Conjugated linoleic acids lower the release of eicosanoids and nitric oxide from human aortic endothelial cells. | 2003 | J. Nutr. | pmid:14652352 |
| Ziser A et al. | Propofol does not induce pulmonary dysfunction in stressed endotoxic pigs receiving Intralipid. | 2003 | Crit. Care Med. | pmid:12847400 |
| Sánchez-Muniz FJ et al. | Platelet aggregation, thromboxane production and thrombogenic ratio in postmenopausal women consuming high oleic acid-sunflower oil or palmolein. | 2003 | Eur J Nutr | pmid:14673602 |
| Chen Z et al. | [Correlation between TXB2, 6-Keto-PGF1alpha and liver metastasis in rats model with blood stasis]. | 2003 | Zhong Xi Yi Jie He Xue Bao | pmid:15339561 |
| He LQ et al. | [Effect and mechanism of Tangshenning Recipe on micro-albuminuria in rats with early diabetic nephropathy]. | 2003 | Zhong Xi Yi Jie He Xue Bao | pmid:15339583 |
| Al-Waili NS and Boni NS | Natural honey lowers plasma prostaglandin concentrations in normal individuals. | 2003 | J Med Food | pmid:12935324 |
| Gu L et al. | [Advances in the study on molecular mechanism of diabetic nephropathy treated with Rheum officinale]. | 2003 | Zhongguo Zhong Yao Za Zhi | pmid:15224660 |
| Jones AE et al. | Inhibition of prostaglandin synthesis during polystyrene microsphere-induced pulmonary embolism in the rat. | 2003 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:12639842 |
| De Cristofaro R et al. | Lipid and protein oxidation contribute to a prothrombotic state in patients with type 2 diabetes mellitus. | 2003 | J. Thromb. Haemost. | pmid:12871497 |
| Davì G et al. | Enhanced lipid peroxidation and platelet activation in the early phase of type 1 diabetes mellitus: role of interleukin-6 and disease duration. | 2003 | Circulation | pmid:12810609 |
| Sheu JR et al. | Inhibitory mechanisms of metallothionein on platelet aggregation in in vitro and platelet plug formation in in vivo experiments. | 2003 | Exp. Biol. Med. (Maywood) | pmid:14681547 |
| Al-Madaney MM et al. | Effects of lipid-esterified conjugated linoleic acid isomers on platelet function: evidence for stimulation of platelet phospholipase activity. | 2003 | Biochim. Biophys. Acta | pmid:14729070 |
| Fujii S et al. | L-arginine reverses p47phox and gp91phox expression induced by high salt in Dahl rats. | 2003 | Hypertension | pmid:14504257 |
| De León EJ et al. | A new chloroquinolinyl chalcone derivative as inhibitor of inflammatory and immune response in mice and rats. | 2003 | J. Pharm. Pharmacol. | pmid:14604476 |
| Dong WG et al. | Ameliorative effects of sodium ferulate on experimental colitis and their mechanisms in rats. | 2003 | World J. Gastroenterol. | pmid:14606091 |
| De La Cruz JP et al. | Differences in the effects of extended-release aspirin and plain-formulated aspirin on prostanoids and nitric oxide in healthy volunteers. | 2003 | Fundam Clin Pharmacol | pmid:12803576 |
| Guyton K et al. | Peroxisome proliferator-activated receptor-gamma agonists modulate macrophage activation by gram-negative and gram-positive bacterial stimuli. | 2003 | Shock | pmid:12813370 |
| Montuschi P et al. | Exhaled leukotrienes and prostaglandins in COPD. | 2003 | Thorax | pmid:12832671 |
| Wolfram RM et al. | Narghile (water pipe) smoking influences platelet function and (iso-)eicosanoids. | 2003 | Life Sci. | pmid:14575812 |
| Stephenson AH et al. | Differential effects of 5,6-EET on segmental pulmonary vasoactivity in the rabbit. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12609822 |
| Beck-Speier I et al. | Sulfur-related air pollutants induce the generation of platelet-activating factor, 5-lipoxygenase- and cyclooxygenase-products in canine alveolar macrophages via activation of phospholipases A2. | 2003 | Prostaglandins Other Lipid Mediat. | pmid:14518563 |
| Seebacher F and Franklin CE | Prostaglandins are important in thermoregulation of a reptile (Pogona vitticeps). | 2003 | Proc. Biol. Sci. | pmid:12952634 |
| Cipollone F et al. | Modulation of aspirin-insensitive eicosanoid biosynthesis by 6-methylprednisolone in unstable angina. | 2003 | Circulation | pmid:12515743 |
| Fike CD et al. | Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigs. | 2003 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:12388340 |
| Halushka MK et al. | Genetic variation in cyclooxygenase 1: effects on response to aspirin. | 2003 | Clin. Pharmacol. Ther. | pmid:12545150 |
| Yokoyama Y et al. | Role of thromboxane A2 in early BDL-induced portal hypertension. | 2003 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12431905 |
| Li D et al. | Diet rich in saturated fat decreases the ratio of thromboxane/prostacyclin in healthy men. | 2003 | Biomed. Environ. Sci. | pmid:15011964 |
| Huang RJ et al. | [Effect of tetramethylpyrazine on endothelin, von Willebrand factor and thromboxane A2 during cardiopulmonary bypass in patients of congenital heart disease with pulmonary hypertension]. | 2003 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:12764908 |
| Li ZG et al. | [Progress on study of experimental physico-chemical indexes related with ischemic stroke]. | 2003 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:12764922 |
| Tsipas G and Morphake P | Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity. | 2003 | J. Nutr. Biochem. | pmid:14629893 |
| Sartin JL et al. | Estradiol plus progesterone treatment modulates select elements of the proinflammatory cytokine cascade in steers: attenuated nitric oxide and thromboxane B2 production in endotoxemia. | 2003 | J. Anim. Sci. | pmid:12817503 |
| Ojanen R et al. | Single dose of acetylsalicylic acid prevents thromboxane release after tourniquet ischemia. | 2003 | J Trauma | pmid:12777914 |
| Dionne RA et al. | Dexamethasone suppresses peripheral prostanoid levels without analgesia in a clinical model of acute inflammation. | 2003 | J. Oral Maxillofac. Surg. | pmid:12966473 |
| Tsipas G and Morphake P | Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity. | 2003 | J. Nutr. Biochem. | pmid:12948879 |
| Cerletti C et al. | Pharmacokinetic and pharmacodynamic differences between two low dosages of aspirin may affect therapeutic outcomes. | 2003 | Clin Pharmacokinet | pmid:12959636 |
| Dai H et al. | Effects of diltiazem on platelet activation and cytosolic calcium during percutaneous transluminal coronary angioplasty. | 2003 | Postgrad Med J | pmid:13679549 |
| Liu H et al. | Clinical implication of the changes of cAMP, TXA2 and PGI2 in CSF of asphyxiated newborns. | 2003 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:12973949 |
| Hart RG et al. | Aspirin dosage and thromboxane synthesis in patients with vascular disease. | 2003 | Pharmacotherapy | pmid:12741431 |
| Pfeiffer S et al. | Hyperacute lung rejection in the pig-to-human model. III. Platelet receptor inhibitors synergistically modulate complement activation and lung injury. | 2003 | Transplantation | pmid:12698079 |
| Arifah AK et al. | Pharmacodynamics, chiral pharmacokinetics and PK-PD modelling of ketoprofen in the goat. | 2003 | J. Vet. Pharmacol. Ther. | pmid:12667184 |
| Ji Y et al. | Thrombosis and its significance after experimental pulmonary thromboembolism. | 2003 | Chin. Med. J. | pmid:12667387 |