propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.
To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with propionic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Aschenbach JR et al. | Bicarbonate-dependent and bicarbonate-independent mechanisms contribute to nondiffusive uptake of acetate in the ruminal epithelium of sheep. | 2009 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:19264953 |
Tyagi S et al. | Mechanism of n-butyrate uptake in the human proximal colonic basolateral membranes. | 2002 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11897627 |
Parhar K et al. | Short-chain fatty acid mediated phosphorylation of heat shock protein 25: effects on camptothecin-induced apoptosis. | 2006 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16469826 |
Grider JR and Piland BE | The peristaltic reflex induced by short-chain fatty acids is mediated by sequential release of 5-HT and neuronal CGRP but not BDNF. | 2007 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16973914 |
Spitzer KW et al. | Generation of intracellular pH gradients in single cardiac myocytes with a microperfusion system. | 2000 | Am. J. Physiol. Heart Circ. Physiol. | pmid:10749735 |
Purmal C et al. | Propionate stimulates pyruvate oxidation in the presence of acetate. | 2014 | Am. J. Physiol. Heart Circ. Physiol. | pmid:25320331 |
Carvalho RA et al. | TCA cycle kinetics in the rat heart by analysis of (13)C isotopomers using indirect (1)H. | 2001 | Am. J. Physiol. Heart Circ. Physiol. | pmid:11514314 |
Nomura N et al. | CaMKII-dependent reactivation of SR Ca(2+) uptake and contractile recovery during intracellular acidosis. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12063291 |
Ragavan M et al. | A comprehensive analysis of myocardial substrate preference emphasizes the need for a synchronized fluxomic/metabolomic research design. | 2017 | Am. J. Physiol. Heart Circ. Physiol. | pmid:28411229 |
Maouyo D et al. | pH heterogeneity at intracellular and extracellular plasma membrane sites in HT29-C1 cell monolayers. | 2000 | Am. J. Physiol., Cell Physiol. | pmid:10794671 |
Stewart G et al. | Mouse GPR40 heterologously expressed in Xenopus oocytes is activated by short-, medium-, and long-chain fatty acids. | 2006 | Am. J. Physiol., Cell Physiol. | pmid:16267104 |
Kisidayová S et al. | Effects of high- and low-fiber diets on fecal fermentation and fecal microbial populations of captive chimpanzees. | 2009 | Am. J. Primatol. | pmid:19367605 |
Ushida K et al. | Nutritional significance of the selective ingestion of Albizia zygia gum exudate by wild chimpanzees in Bossou, Guinea. | 2006 | Am. J. Primatol. | pmid:16429414 |
Owens SW et al. | Developmental alterations in the regulation of glucagon and insulin secretion in Holstein calves. | 1986 | Am. J. Vet. Res. | pmid:3513676 |
Brosey BP et al. | Gastrointestinal volatile fatty acid concentrations and pH in cats. | 2000 | Am. J. Vet. Res. | pmid:10772097 |
Mcmanus CM et al. | Effect of short-chain fatty acids on contraction of smooth muscle in the canine colon. | 2002 | Am. J. Vet. Res. | pmid:11843133 |
Ward GE and Nelson DI | Effects of dietary milk fat (whole milk) and propionic acid on intestinal coliforms and lactobacilli in calves. | 1982 | Am. J. Vet. Res. | pmid:7049020 |
Nadeau JA et al. | Effects of hydrochloric, acetic, butyric, and propionic acids on pathogenesis of ulcers in the nonglandular portion of the stomach of horses. | 2003 | Am. J. Vet. Res. | pmid:12693528 |
Mills SW et al. | Evaluation of the effects of short-chain fatty acids and extracellular pH on bovine neutrophil function in vitro. | 2006 | Am. J. Vet. Res. | pmid:17078753 |
Merritt AM and Smith DA | Osmolarity and volatile fatty acid content of feces from horses with chronic diarrhea. | 1980 | Am. J. Vet. Res. | pmid:7436082 |