propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.
To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with propionic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Selwet M | Effect of organic acids on numbers of yeasts and mould fungi and aerobic stability in the silage of corn. | 2008 | Pol J Vet Sci | pmid:18683540 |
Wang S et al. | Insertion of an esterase gene into a specific locust pathogen (Metarhizium acridum) enables it to infect caterpillars. | 2011 | PLoS Pathog. | pmid:21731492 |
van der Geize R et al. | The steroid catabolic pathway of the intracellular pathogen Rhodococcus equi is important for pathogenesis and a target for vaccine development. | 2011 | PLoS Pathog. | pmid:21901092 |
Tabouret G et al. | Mycobacterium leprae phenolglycolipid-1 expressed by engineered M. bovis BCG modulates early interaction with human phagocytes. | 2010 | PLoS Pathog. | pmid:20975946 |
Soanes DM et al. | Genome-wide transcriptional profiling of appressorium development by the rice blast fungus Magnaporthe oryzae. | 2012 | PLoS Pathog. | pmid:22346750 |
Jani D et al. | HDP-a novel heme detoxification protein from the malaria parasite. | 2008 | PLoS Pathog. | pmid:18437218 |
Jain M and Cox JS | Interaction between polyketide synthase and transporter suggests coupled synthesis and export of virulence lipid in M. tuberculosis. | 2005 | PLoS Pathog. | pmid:16201014 |
Singh A et al. | Mycobacterium tuberculosis WhiB3 maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response. | 2009 | PLoS Pathog. | pmid:19680450 |
Ekworomadu MT et al. | Differential function of lip residues in the mechanism and biology of an anthrax hemophore. | 2012 | PLoS Pathog. | pmid:22412371 |
Baughn AD et al. | An anaerobic-type alpha-ketoglutarate ferredoxin oxidoreductase completes the oxidative tricarboxylic acid cycle of Mycobacterium tuberculosis. | 2009 | PLoS Pathog. | pmid:19936047 |
Wójtowicz H et al. | Unique structure and stability of HmuY, a novel heme-binding protein of Porphyromonas gingivalis. | 2009 | PLoS Pathog. | pmid:19424422 |
Lam KK et al. | Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis. | 2012 | PLoS Pathog. | pmid:22589723 |
Griffin JE et al. | High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism. | 2011 | PLoS Pathog. | pmid:21980284 |
Astarie-Dequeker C et al. | Phthiocerol dimycocerosates of M. tuberculosis participate in macrophage invasion by inducing changes in the organization of plasma membrane lipids. | 2009 | PLoS Pathog. | pmid:19197369 |
Brodin P et al. | High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling. | 2010 | PLoS Pathog. | pmid:20844580 |
Mulcahy H et al. | Drosophila melanogaster as an animal model for the study of Pseudomonas aeruginosa biofilm infections in vivo. | 2011 | PLoS Pathog. | pmid:21998591 |
Homolka S et al. | Functional genetic diversity among Mycobacterium tuberculosis complex clinical isolates: delineation of conserved core and lineage-specific transcriptomes during intracellular survival. | 2010 | PLoS Pathog. | pmid:20628579 |
Doheny JG et al. | Telomeric position effect--a third silencing mechanism in eukaryotes. | 2008 | PLoS ONE | pmid:19057646 |
Hu S et al. | The microbe-derived short chain fatty acid butyrate targets miRNA-dependent p21 gene expression in human colon cancer. | 2011 | PLoS ONE | pmid:21283757 |
Yévenes GE and Zeilhofer HU | Molecular sites for the positive allosteric modulation of glycine receptors by endocannabinoids. | 2011 | PLoS ONE | pmid:21901142 |
Alves SP et al. | Does the fat tailed Damara ovine breed have a distinct lipid metabolism leading to a high concentration of branched chain fatty acids in tissues? | 2013 | PLoS ONE | pmid:24204803 |
Enoki M et al. | Comparative proteomic analysis of Methanothermobacter themautotrophicus ΔH in pure culture and in co-culture with a butyrate-oxidizing bacterium. | 2011 | PLoS ONE | pmid:21904627 |
Bassaganya-Riera J et al. | Probiotic bacteria produce conjugated linoleic acid locally in the gut that targets macrophage PPAR γ to suppress colitis. | 2012 | PLoS ONE | pmid:22363592 |
Brown CT et al. | Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes. | 2011 | PLoS ONE | pmid:22043294 |
Masiewicz P et al. | A novel role of the PrpR as a transcription factor involved in the regulation of methylcitrate pathway in Mycobacterium tuberculosis. | 2012 | PLoS ONE | pmid:22916289 |
Steiner C et al. | Bile acid metabolites in serum: intraindividual variation and associations with coronary heart disease, metabolic syndrome and diabetes mellitus. | 2011 | PLoS ONE | pmid:22110577 |
Poeggeler B et al. | A novel endogenous indole protects rodent mitochondria and extends rotifer lifespan. | 2010 | PLoS ONE | pmid:20421998 |
Hahn MW et al. | The passive yet successful way of planktonic life: genomic and experimental analysis of the ecology of a free-living polynucleobacter population. | 2012 | PLoS ONE | pmid:22448227 |
Tea I et al. | 1H-NMR-based metabolic profiling of maternal and umbilical cord blood indicates altered materno-foetal nutrient exchange in preterm infants. | 2012 | PLoS ONE | pmid:22291897 |
Gupta V et al. | Crystal structure of Bfr A from Mycobacterium tuberculosis: incorporation of selenomethionine results in cleavage and demetallation of haem. | 2009 | PLoS ONE | pmid:19946376 |
Takahashi KH et al. | Environmental stress-dependent effects of deletions encompassing Hsp70Ba on canalization and quantitative trait asymmetry in Drosophila melanogaster. | 2011 | PLoS ONE | pmid:21541022 |
Catterson JH et al. | Dietary modulation of Drosophila sleep-wake behaviour. | 2010 | PLoS ONE | pmid:20706579 |
Dalmasso M et al. | A temporal-omic study of Propionibacterium freudenreichii CIRM-BIA1 adaptation strategies in conditions mimicking cheese ripening in the cold. | 2012 | PLoS ONE | pmid:22253706 |
Chu CP et al. | Roles of molecular layer interneurons in sensory information processing in mouse cerebellar cortex Crus II in vivo. | 2012 | PLoS ONE | pmid:22623975 |
Choi J et al. | Pathophysiological and neurobehavioral characteristics of a propionic acid-mediated autism-like rat model. | 2018 | PLoS ONE | pmid:29447237 |
Frisa PS and Jacobberger JW | Cell cycle-related cyclin b1 quantification. | 2009 | PLoS ONE | pmid:19763267 |
Jawara M et al. | Field testing of different chemical combinations as odour baits for trapping wild mosquitoes in The Gambia. | 2011 | PLoS ONE | pmid:21637337 |
Sripadi P et al. | Direct detection of diverse metabolic changes in virally transformed and tax-expressing cells by mass spectrometry. | 2010 | PLoS ONE | pmid:20830293 |
Kroth PG et al. | A model for carbohydrate metabolism in the diatom Phaeodactylum tricornutum deduced from comparative whole genome analysis. | 2008 | PLoS ONE | pmid:18183306 |
Abbott AD et al. | Early-to-mid gestation fetal testosterone increases right hand 2D:4D finger length ratio in polycystic ovary syndrome-like monkeys. | 2012 | PLoS ONE | pmid:22927929 |
van Vuurden DG et al. | Attenuated AMPA receptor expression allows glioblastoma cell survival in glutamate-rich environment. | 2009 | PLoS ONE | pmid:19536293 |
Anderson I et al. | Novel insights into the diversity of catabolic metabolism from ten haloarchaeal genomes. | 2011 | PLoS ONE | pmid:21633497 |
Lin HV et al. | Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms. | 2012 | PLoS ONE | pmid:22506074 |
Armstrong GA et al. | Glial Hsp70 protects K+ homeostasis in the Drosophila brain during repetitive anoxic depolarization. | 2011 | PLoS ONE | pmid:22174942 |
Baskaran P et al. | Identification of residues in the heme domain of soluble guanylyl cyclase that are important for basal and stimulated catalytic activity. | 2011 | PLoS ONE | pmid:22096512 |
Spindler SR et al. | Novel protein kinase signaling systems regulating lifespan identified by small molecule library screening using Drosophila. | 2012 | PLoS ONE | pmid:22363408 |
Todd JD et al. | The Ruegeria pomeroyi acuI gene has a role in DMSP catabolism and resembles yhdH of E. coli and other bacteria in conferring resistance to acrylate. | 2012 | PLoS ONE | pmid:22563425 |
Fernández-Ayala DJ et al. | Gene expression in a Drosophila model of mitochondrial disease. | 2010 | PLoS ONE | pmid:20066047 |
Ueyama M et al. | Increased apoptosis of myoblasts in Drosophila model for the Walker-Warburg syndrome. | 2010 | PLoS ONE | pmid:20644630 |
Siebers B et al. | The complete genome sequence of Thermoproteus tenax: a physiologically versatile member of the Crenarchaeota. | 2011 | PLoS ONE | pmid:22003381 |