propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.
To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with propionic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Busse SC and Jue T | Two-dimensional NMR characterization of the deoxymyoglobin heme pocket. | 1994 | Biochemistry | pmid:8086410 |
LeMagueres P et al. | Crystal structure at 1.45 A resolution of alanine racemase from a pathogenic bacterium, Pseudomonas aeruginosa, contains both internal and external aldimine forms. | 2003 | Biochemistry | pmid:14674749 |
Ibrahim M et al. | Soluble guanylate cyclase is activated differently by excess NO and by YC-1: resonance Raman spectroscopic evidence. | 2010 | Biochemistry | pmid:20459051 |
Louie GV et al. | Role of phenylalanine-82 in yeast iso-1-cytochrome c and remote conformational changes induced by a serine residue at this position. | 1988 | Biochemistry | pmid:2849996 |
Zhao D et al. | Structure and stability effects of the mutation of glycine 34 to serine in Rhodobacter capsulatus cytochrome c(2). | 2000 | Biochemistry | pmid:10747794 |
Seibold SA et al. | Water chain formation and possible proton pumping routes in Rhodobacter sphaeroides cytochrome c oxidase: a molecular dynamics comparison of the wild type and R481K mutant. | 2005 | Biochemistry | pmid:16060656 |
Egan RM et al. | Mechanism of urocanase as studied by deuterium isotope effects and labeling patterns. | 1981 | Biochemistry | pmid:6110440 |
Meharenna YT et al. | Engineering ascorbate peroxidase activity into cytochrome c peroxidase. | 2008 | Biochemistry | pmid:18771292 |
Morollo AA et al. | Structure of a Michaelis complex analogue: propionate binds in the substrate carboxylate site of alanine racemase. | 1999 | Biochemistry | pmid:10079072 |
Nagai M et al. | Heme structure of hemoglobin M Iwate [alpha 87(F8)His-->Tyr]: a UV and visible resonance Raman study. | 2000 | Biochemistry | pmid:11052661 |
Santucci R et al. | Anion size modulates the structure of the A state of cytochrome c. | 2000 | Biochemistry | pmid:11027143 |
Yoshimura H et al. | Specific hydrogen-bonding networks responsible for selective O2 sensing of the oxygen sensor protein HemAT from Bacillus subtilis. | 2006 | Biochemistry | pmid:16819829 |
Nakamura S et al. | Structure of cytochrome c552 from a moderate thermophilic bacterium, Hydrogenophilus thermoluteolus: comparative study on the thermostability of cytochrome c. | 2006 | Biochemistry | pmid:16681384 |
Cutler RL et al. | Role of arginine-38 in regulation of the cytochrome c oxidation-reduction equilibrium. | 1989 | Biochemistry | pmid:2545252 |
Peyton DH et al. | Proton nuclear magnetic resonance study of the molecular and electronic structure of the heme cavity in Aplysia cyanometmyoglobin. | 1989 | Biochemistry | pmid:2548594 |
Shokhireva TKh et al. | Assignment of heme resonances and determination of the electronic structures of high- and low-spin nitrophorin 2 by 1H and 13C NMR spectroscopy: an explanation of the order of heme methyl resonances in high-spin ferriheme proteins. | 2003 | Biochemistry | pmid:12534280 |
Hector ML and Fall RR | Multiple acyl-coenzyme A carboxylases in Pseudomonas citronellolis. | 1976 | Biochemistry | pmid:8091 |
Balland V et al. | Functional implications of the propionate 7-arginine 220 interaction in the FixLH oxygen sensor from Bradyrhizobium japonicum. | 2006 | Biochemistry | pmid:16475796 |
Omura S et al. | Studies on the biosynthesis of 16-membered macrolide antibiotics using carbon-13 nuclear magnetic resonance spectroscopy. | 1977 | Biochemistry | pmid:18162 |
Mileni M et al. | Probing heme propionate involvement in transmembrane proton transfer coupled to electron transfer in dihemic quinol:fumarate reductase by 13C-labeling and FTIR difference spectroscopy. | 2005 | Biochemistry | pmid:16342962 |
Barrows TP and Poulos TL | Role of electrostatics and salt bridges in stabilizing the compound I radical in ascorbate peroxidase. | 2005 | Biochemistry | pmid:16245922 |
Behr J et al. | Functional properties of the heme propionates in cytochrome c oxidase from Paracoccus denitrificans. Evidence from FTIR difference spectroscopy and site-directed mutagenesis. | 2000 | Biochemistry | pmid:10684616 |
Delker SL et al. | Role of zinc in isoform-selective inhibitor binding to neuronal nitric oxide synthase . | 2010 | Biochemistry | pmid:21138269 |
Harada K et al. | Structure and ligand binding properties of myoglobins reconstituted with monodepropionated heme: functional role of each heme propionate side chain. | 2007 | Biochemistry | pmid:17636874 |
Key J and Moffat K | Crystal structures of deoxy and CO-bound bjFixLH reveal details of ligand recognition and signaling. | 2005 | Biochemistry | pmid:15779889 |
Sherman MM and Hutchinson CR | Biosynthesis of lasalocid A: biochemical mechanism for assembly of the carbon framework. | 1987 | Biochemistry | pmid:3828316 |
Zhang H et al. | Characterization of the high-spin heme x in the cytochrome b6f complex of oxygenic photosynthesis. | 2004 | Biochemistry | pmid:15610027 |
Grimshaw CE et al. | Use of isotope effects and pH studies to determine the chemical mechanism of Bacillus subtilis L-alanine dehydrogenase. | 1981 | Biochemistry | pmid:6794612 |
Mendoza MF et al. | Human NAD(P)H:quinone oxidoreductase type I (hNQO1) activation of quinone propionic acid trigger groups. | 2012 | Biochemistry | pmid:22989153 |
Sivuk VF et al. | Purification and characteristics of functional properties of soluble nucleoside triphosphatase (apyrase) from bovine brain. | 2008 | Biochemistry Mosc. | pmid:18976223 |
Kondakova AN et al. | New structures of the O-specific polysaccharides of Proteus. 3. Polysaccharides containing non-carbohydrate organic acids. | 2003 | Biochemistry Mosc. | pmid:12765528 |
Morishima I and Iizuka T | Nuclear magnetic resonance studies of hemoproteins. IV. Hindered rotation of heme side methyl group as a probe for studying van der Waals contacts in the heme side environments of myoglobin derivatives. | 1975 | Biochim. Biophys. Acta | pmid:1169971 |
Enser U and Heber U | Metabolic regulation by pH gradients. Inhibition of photosynthesis by indirect proton transfer across the chloroplast envelope. | 1980 | Biochim. Biophys. Acta | pmid:6251871 |
Yount EA and Harris RA | Studies on the inhibition of gluconeogenesis by oxalate. | 1980 | Biochim. Biophys. Acta | pmid:6778509 |
Koutsoupakis C et al. | Time-resolved step-scan Fourier transform infrared investigation of heme-copper oxidases: implications for O2 input and H2O/H+ output channels. | 2004 | Biochim. Biophys. Acta | pmid:15100050 |
Sokolov S et al. | Ysp2 mediates death of yeast induced by amiodarone or intracellular acidification. | Biochim. Biophys. Acta | pmid:16962064 | |
Sorenson MM and De Meis L | Effects of anions, pH and magnesium on calcium accumulation and release by sarcoplasmic reticulum vesicles. | 1977 | Biochim. Biophys. Acta | pmid:16250336 |
Taylor A et al. | The effects of propionate on sodium transport by the toad bladder. Evidence for a metabolic mode of action. | 1973 | Biochim. Biophys. Acta | pmid:4198138 |
Riistama S et al. | Interaction between the formyl group of heme a and arginine 54 in cytochrome aa(3) from Paracoccus denitrificans. | 2000 | Biochim. Biophys. Acta | pmid:10611451 |
Tomaro ML et al. | The oxidation of hemins by microsomal heme oxygenase. Structural requirements for the retention of substrate activity. | 1984 | Biochim. Biophys. Acta | pmid:6549143 |
Wirthensohn G and Guder WG | Phosphatidylcholine biosynthesis in rabbit kidney tubule suspensions. Effect of metabolic substrates on precursor incorporation. | 1983 | Biochim. Biophys. Acta | pmid:6860690 |
Alonso WR and Nelson DA | A novel yeast histone deacetylase: partial characterization and development of an activity assay. | 1986 | Biochim. Biophys. Acta | pmid:3513841 |
Ku EC and Wasvary JM | Inhibition of prostaglandin synthase by pirprofen. Studies with sheep seminal vesicle enzyme. | 1975 | Biochim. Biophys. Acta | pmid:804924 |
Moore GR et al. | A spectroscopic investigation of the structure and redox properties of Escherichia coli cytochrome b-562. | 1985 | Biochim. Biophys. Acta | pmid:2986699 |
Martin JF and Mcdaniel LE | Specific inhibition of candicidin biosynthesis by the lipogenic inhibitor cerulenin. | 1975 | Biochim. Biophys. Acta | pmid:811262 |
Yamamoto Y et al. | 1H-NMR study of dynamics and thermodynamics of Cl- binding to ferric hemoglobin of a midge larva (Tokunagayusurika akamusi). | 2003 | Biochim. Biophys. Acta | pmid:14644049 |
Sundqvist KE et al. | Effect of acetate and octanoate on tricarboxylic acid cycle metabolite disposal during propionate oxidation in the perfused rat heart. | 1984 | Biochim. Biophys. Acta | pmid:6487652 |
Fonteriz RI et al. | The role of intracellular acidification in calcium mobilization in human neutrophils. | 1991 | Biochim. Biophys. Acta | pmid:2049405 |
Wall MJ et al. | The effect of short chain fatty acids on transmural electrical potential across rat small intestine in vivo. | 1976 | Biochim. Biophys. Acta | pmid:179592 |
Yoshikawa S et al. | Proton pumping mechanism of bovine heart cytochrome c oxidase. | Biochim. Biophys. Acta | pmid:16904626 | |
Keller RM and Wüthrich K | Assignment of the heme c resonances in the 360 MHz H NMR spectra of cytochrome c. | 1978 | Biochim. Biophys. Acta | pmid:205265 |
Loureiro SO et al. | Propionic and methylmalonic acids increase cAMP levels in slices of cerebral cortex of young rats via adrenergic and glutamatergic mechanisms. | 2005 | Biochim. Biophys. Acta | pmid:15949715 |
Yu MA et al. | Radical formation in cytochrome c oxidase. | 2011 | Biochim. Biophys. Acta | pmid:21718686 |
Hess JJ et al. | On the effects of propionate and other short-chain fatty acids on sodium transport by the toad bladder. | 1975 | Biochim. Biophys. Acta | pmid:236789 |
Henly DC and Berry MN | Relationship between the stimulation of citric acid cycle oxidation and the stimulation of fatty acid esterification and inhibition of ketogenesis by lactate in isolated rat hepatocytes. | 1991 | Biochim. Biophys. Acta | pmid:1828700 |
Lancaster CR et al. | Recent progress on obtaining theoretical and experimental support for the "E-pathway hypothesis" of coupled transmembrane electron and proton transfer in dihaem-containing quinol:fumarate reductase. | 2006 | Biochim. Biophys. Acta | pmid:16790236 |
Knight LC and Welch MJ | Sites of direct and indirect halogenation of albumin. | 1978 | Biochim. Biophys. Acta | pmid:27226 |
Wikström M et al. | Water-gated mechanism of proton translocation by cytochrome c oxidase. | 2003 | Biochim. Biophys. Acta | pmid:12765763 |
Pettigrew GW et al. | Redox potentials of the photosynthetic bacterial cytochromes c2 and the structural bases for variability. | 1978 | Biochim. Biophys. Acta | pmid:28760 |
Zheng X et al. | Computer simulation of water in cytochrome c oxidase. | 2003 | Biochim. Biophys. Acta | pmid:12615353 |
Wasternack C et al. | Pyrimidine-degrading enzymes. Purification and properties of beta-ureidopropionase of Euglena gracilis. | 1979 | Biochim. Biophys. Acta | pmid:115499 |
Trewhella J and Wright PE | 1H-NMR studies of ferric soybean leghemoglobin: assignment of hyperfine shifted resonances of complexes with cyanide, nicotinate, pyridine and azide. | 1980 | Biochim. Biophys. Acta | pmid:7192162 |
Keller R et al. | Contact-shifted resonances in the 1H NMR spectra of cytochrome b5. Resonance identification and spin density distribution in the heme group. | 1976 | Biochim. Biophys. Acta | pmid:5127 |
Hayashi S et al. | Steady-state kinetics and spectral properties of Corynebacterium sarcosine oxidase. | 1983 | Biochim. Biophys. Acta | pmid:6188492 |
Rotsaert FA et al. | Mutations in cytochrome b that affect kinetics of the electron transfer reactions at center N in the yeast cytochrome bc1 complex. | 2008 | Biochim. Biophys. Acta | pmid:18328328 |
Adir N et al. | Refined structure of c-phycocyanin from the cyanobacterium Synechococcus vulcanus at 1.6 A: insights into the role of solvent molecules in thermal stability and co-factor structure. | 2002 | Biochim. Biophys. Acta | pmid:12460674 |
HASSALL H and GREENBERG DM | The oxidation of 4(5)-imidazolone-5(4)-propionic acid to hydantoin-5-propionic acid by xanthine oxidase. | 1963 | Biochim. Biophys. Acta | pmid:13960896 |
Peuhkurinen KJ | Accumulation and disposal of tricarboxylic acid cycle intermediates during propionate oxidation in the isolated perfused rat heart. | 1982 | Biochim. Biophys. Acta | pmid:7138913 |
Fiedor L et al. | Understanding chlorophylls: central magnesium ion and phytyl as structural determinants. | 2008 | Biochim. Biophys. Acta | pmid:18848915 |
Fafournoux P et al. | Propionate transport in rat liver cells. | 1985 | Biochim. Biophys. Acta | pmid:4016114 |
Bear CE et al. | Intracellular pH influences the resting membrane potential of isolated rat hepatocytes. | 1988 | Biochim. Biophys. Acta | pmid:3179283 |
Ticku MK and Olsen RW | gamma-Aminobutyric acid-stimulated chloride permeability in crayfish muscle. | 1977 | Biochim. Biophys. Acta | pmid:836825 |
Ziyadeh FN et al. | Taurine and cell volume maintenance in the shark rectal gland: cellular fluxes and kinetics. | 1988 | Biochim. Biophys. Acta | pmid:2840958 |
Xu J and Voth GA | Redox-coupled proton pumping in cytochrome c oxidase: further insights from computer simulation. | 2008 | Biochim. Biophys. Acta | pmid:18155154 |
TOMLINSON N and MACLEOD RA | The oxidation of propionic acid by a marine bacterium. | 1955 | Biochim. Biophys. Acta | pmid:13304045 |
Dwyer LA et al. | A 13C-NMR study of the biosynthesis of 3-methylpentacosane in the American cockroach. | 1981 | Biochim. Biophys. Acta | pmid:6894252 |
Itoh N et al. | Cloning and biochemical characterization of Co(2+)-activated bromoperoxidase-esterase (perhydrolase) from Pseudomonas putida IF-3 strain. | 2001 | Biochim. Biophys. Acta | pmid:11342031 |
WOOD HG and LEAVER FW | CO2 turnover in the fermentation of 3,4,5 and 6 carbon compounds by the propionic acid bacteria. | Biochim. Biophys. Acta | pmid:13115430 | |
Kay WW | Genetic control of the metabolism of propionate by Escherichia coli K12. | 1972 | Biochim. Biophys. Acta | pmid:4554901 |
Hokland BM and Bremer J | Metabolism and excretion of carnitine and acylcarnitines in the perfused rat kidney. | 1986 | Biochim. Biophys. Acta | pmid:3697382 |
Egawa T et al. | Critical structural role of R481 in cytochrome c oxidase from Rhodobacter sphaeroides. | 2009 | Biochim. Biophys. Acta | pmid:19463779 |
Hiltunen JK and Davis EJ | The disposition of citric acid cycle intermediates by isolated rat heart mitochondria. | 1981 | Biochim. Biophys. Acta | pmid:7306575 |
Jørgensen KE and Sheikh MI | Characteristics of uptake of short chain fatty acids by luminal membrane vesicles from rabbit kidney. | 1986 | Biochim. Biophys. Acta | pmid:3741867 |
Brass EP | Effect of alpha-ketobutyrate on palmitic acid and pyruvate metabolism in isolated rat hepatocytes. | 1986 | Biochim. Biophys. Acta | pmid:3741887 |
Richard E et al. | Genetic heterogeneity in propionic acidemia patients with alpha-subunit defects. Identification of five novel mutations, one of them causing instability of the protein. | 1999 | Biochim. Biophys. Acta | pmid:10101253 |
Yoshikawa S et al. | Structural studies on bovine heart cytochrome c oxidase. | 2012 | Biochim. Biophys. Acta | pmid:22236806 |
Emmanuel B | The relative contribution of propionate, and long-chain even-numbered fatty acids to the production of long-chain odd-numbered fatty acids in rumen bacteria. | 1978 | Biochim. Biophys. Acta | pmid:564207 |
Desire B and Saint-Andre S | [Accelerating effect of heterocyclic quaternary ammonium salts on neutral ester hydrolysis by acetylcholinesterase and butyrylcholinesterase (author's transl)]. | 1981 | Biochim. Biophys. Acta | pmid:7260096 |
Gens JS et al. | Different ionic conditions prompt NHE2 and NHE3 translocation to the plasma membrane. | 2007 | Biochim. Biophys. Acta | pmid:17303069 |
Ellfolk N and Perttilä U | Heme sulfuric anhydrides as soybean leghemoglobin structure probes. | 1978 | Biochim. Biophys. Acta | pmid:656461 |
Scaife JR and Tichivangana JZ | Short chain acyl-CoA synthetases in ovine rumen epithelium. | 1980 | Biochim. Biophys. Acta | pmid:7407228 |
Clavero S et al. | Functional characterization of PCCA mutations causing propionic acidemia. | 2002 | Biochim. Biophys. Acta | pmid:12385775 |
Kaila VR et al. | The identity of the transient proton loading site of the proton-pumping mechanism of cytochrome c oxidase. | 2011 | Biochim. Biophys. Acta | pmid:20831859 |
Honig GR et al. | Hemoglobin F Lódź (G gamma I 44 Ser replaced by Arg). A newly identified variant from an American infant of Polish descent. | 1982 | Biochim. Biophys. Acta | pmid:6814491 |
Benavides J et al. | Glycine transport in rat brain and liver mitochondria. | 1980 | Biochim. Biophys. Acta | pmid:7388024 |
Jacobson G et al. | Human pituitary thyrotropin. Isolation of alpha and beta subunits by hydrophobic interaction chromatography. | 1978 | Biochim. Biophys. Acta | pmid:708778 |
Hellwig P et al. | Spectroscopic study on the communication between a heme a3 propionate, Asp399 and the binuclear center of cytochrome c oxidase from Paracoccus denitrificans. | 2008 | Biochim. Biophys. Acta | pmid:18078804 |
Ford SH | Amidation of, and (R)-1-amino-2-propanol attachment to, the corrin ring during vitamin B-12 biosynthesis by Clostridium tetanomorphum extracts. | 1985 | Biochim. Biophys. Acta | pmid:4027268 |
Trotter PJ and Storch J | 3-[p-(6-phenyl)-1,3,5-hexatrienyl]phenylpropionic acid (PA-DPH): characterization as a fluorescent membrane probe and binding to fatty acid binding proteins. | 1989 | Biochim. Biophys. Acta | pmid:2742883 |
Al-Lahham SH et al. | Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms. | 2010 | Biochim. Biophys. Acta | pmid:20691280 |