propionic acid
propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.
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Introduction
To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with propionic acid?
propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with propionic acid
PubChem Associated disorders and diseases
What pathways are associated with propionic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with propionic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with propionic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with propionic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with propionic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with propionic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with propionic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ishihara K et al. | Identification of urinary biomarkers useful for distinguishing a difference in mechanism of toxicity in rat model of cholestasis. | 2009 | Basic Clin. Pharmacol. Toxicol. | pmid:19486331 |
| Taegtmeyer H | On the inability of ketone bodies to serve as the only energy providing substrate for rat heart at physiological work load. | 1983 Jul-Aug | Basic Res. Cardiol. | pmid:6626122 |
| Kooij V et al. | Protein kinase C alpha and epsilon phosphorylation of troponin and myosin binding protein C reduce Ca2+ sensitivity in human myocardium. | 2010 | Basic Res. Cardiol. | pmid:19655190 |
| Yonekura K et al. | Inhibition of carnitine synthesis modulates protein contents of the cardiac sarcoplasmic reticulum Ca2+-ATPase and hexokinase type I in rat hearts with myocardial infarction. | 2000 | Basic Res. Cardiol. | pmid:11099160 |
| Neulen A et al. | The cardiac troponin C mutation Leu29Gln found in a patient with hypertrophic cardiomyopathy does not alter contractile parameters in skinned murine myocardium. | 2009 | Basic Res. Cardiol. | pmid:19506933 |
| Laing DG and Willcox ME | An investigation of the mechanisms of odor suppression using physical and dichorhinic mixtures. | 1987 Nov-Dec | Behav. Brain Res. | pmid:3426790 |
| MacFabe DF et al. | Effects of the enteric bacterial metabolic product propionic acid on object-directed behavior, social behavior, cognition, and neuroinflammation in adolescent rats: Relevance to autism spectrum disorder. | 2011 | Behav. Brain Res. | pmid:20937326 |
| Shultz SR et al. | Intracerebroventricular injections of the enteric bacterial metabolic product propionic acid impair cognition and sensorimotor ability in the Long-Evans rat: further development of a rodent model of autism. | 2009 | Behav. Brain Res. | pmid:19154758 |
| Shultz SR et al. | Intracerebroventricular injection of propionic acid, an enteric metabolite implicated in autism, induces social abnormalities that do not differ between seizure-prone (FAST) and seizure-resistant (SLOW) rats. | 2015 | Behav. Brain Res. | pmid:25446754 |
| Foley KA et al. | Sexually dimorphic effects of prenatal exposure to lipopolysaccharide, and prenatal and postnatal exposure to propionic acid, on acoustic startle response and prepulse inhibition in adolescent rats: relevance to autism spectrum disorders. | 2015 | Behav. Brain Res. | pmid:25300465 |
| MacFabe DF et al. | Neurobiological effects of intraventricular propionic acid in rats: possible role of short chain fatty acids on the pathogenesis and characteristics of autism spectrum disorders. | 2007 | Behav. Brain Res. | pmid:16950524 |
| Ossenkopp KP et al. | Systemic treatment with the enteric bacterial fermentation product, propionic acid, produces both conditioned taste avoidance and conditioned place avoidance in rats. | 2012 | Behav. Brain Res. | pmid:22085877 |
| Humphries PS et al. | ADDP and PS-PPh3: an efficient Mitsunobu protocol for the preparation of pyridine ether PPAR agonists. | 2006 | Beilstein J Org Chem | pmid:17076898 |
| Jervis PJ and Cox LR | Tether-directed synthesis of highly substituted oxasilacycles via an intramolecular allylation employing allylsilanes. | 2007 | Beilstein J Org Chem | pmid:17288602 |
| Guazzelli G et al. | Synthesis of (-)-Indolizidine 167B based on domino hydroformylation/cyclization reactions. | 2008 | Beilstein J Org Chem | pmid:18197967 |
| Havenaar R | Intestinal health functions of colonic microbial metabolites: a review. | 2011 | Benef Microbes | pmid:21840809 |
| Roelofsen H et al. | The interaction of short-chain fatty acids with adipose tissue: relevance for prevention of type 2 diabetes. | 2010 | Benef Microbes | pmid:21831781 |
| Bird AR et al. | Resistant starch, large bowel fermentation and a broader perspective of prebiotics and probiotics. | 2010 | Benef Microbes | pmid:21831780 |
| Binsl TW et al. | Measuring non-steady-state metabolic fluxes in starch-converting faecal microbiota in vitro. | 2010 | Benef Microbes | pmid:21831778 |
| Mäkivuokko H et al. | Synbiotic effects of lactitol and Lactobacillus acidophilus NCFM™ in a semi-continuous colon fermentation model. | 2010 | Benef Microbes | pmid:21840801 |
| Fernando WM et al. | Diets supplemented with chickpea or its main oligosaccharide component raffinose modify faecal microbial composition in healthy adults. | 2010 | Benef Microbes | pmid:21831757 |
| Singh S et al. | Lactobacillus rhamnosus NCDC17 ameliorates type-2 diabetes by improving gut function, oxidative stress and inflammation in high-fat-diet fed and streptozotocintreated rats. | 2017 | Benef Microbes | pmid:28008783 |
| Luo J et al. | Potential influence of dairy propionibacteria on the growth and acid metabolism of Streptococcus bovis and Megasphaera elsdenii. | 2017 | Benef Microbes | pmid:27824275 |
| Fuhrmann H et al. | [The evaluation of hormone and metabolite profiles after the infusion of glucose, propionate and butyrate in cattle]. | 1989 | Berl. Munch. Tierarztl. Wochenschr. | pmid:2764872 |
| Oizumi J et al. | Propionate metabolism by cultured skin fibroblasts from normal individuals and patients with methylmalonicaciduria and propionicacidemia. | 1981 | Biochem Med | pmid:7295302 |
| Nofer JR et al. | Low density lipoproteins inhibit the Na+/H+ antiport in human platelets via activation of p38MAP kinase. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16380078 |
| Riester D et al. | Members of the histone deacetylase superfamily differ in substrate specificity towards small synthetic substrates. | 2004 | Biochem. Biophys. Res. Commun. | pmid:15485670 |
| Cantenys D et al. | Covalent attachment of insulin to the outer surface of liposomes. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6197974 |
| Swaminath G et al. | Mutational analysis of G-protein coupled receptor--FFA2. | 2011 | Biochem. Biophys. Res. Commun. | pmid:21216233 |
| Oda Y and Kasai K | Photochemical cross-linking of beta-galactoside-binding lectin to polylactosamino-proteoglycan of chick embryonic skin. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6487329 |
| Wächtershäuser A et al. | PPAR-gamma is selectively upregulated in Caco-2 cells by butyrate. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10833422 |
| Palmeira CM et al. | Induction of the mitochondrial permeability transition in vitro by short-chain carboxylic acids. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10833431 |
| Grinstein S and Furuya W | Amiloride-sensitive Na+/H+ exchange in human neutrophils: mechanism of activation by chemotactic factors. | 1984 | Biochem. Biophys. Res. Commun. | pmid:6087813 |
| Parsons WH et al. | Benzolactams. A new class of converting enzyme inhibitors. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6318742 |
| Ramos-Santana BJ and López-Garriga J | Tyrosine B10 triggers a heme propionate hydrogen bonding network loop with glutamine E7 moiety. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22809503 |
| Sha'afi RI and Molski TF | Signalling for increased cytoskeletal actin in neutrophils. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3036146 |
| Carini R et al. | Evidence for a sodium-dependent calcium influx in isolated rat hepatocytes undergoing ATP depletion. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8037733 |
| Staecker JL et al. | Stimulation of DNA synthesis in primary cultures of adult rat hepatocytes by sodium butyrate. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3632683 |
| Cathelineau L et al. | Effect of propionate and pyruvate on citrulline synthesis and ATP content in rat liver mitochondria. | 1979 | Biochem. Biophys. Res. Commun. | pmid:496983 |
| Rabier D et al. | Propionate and succinate effects on acetyl glutamate biosynthesis by rat liver mitochondria. | 1979 | Biochem. Biophys. Res. Commun. | pmid:518644 |
| Hagey LR and Krisans SK | Degradation of cholesterol to propionic acid by rat liver peroxisomes. | 1982 | Biochem. Biophys. Res. Commun. | pmid:7138522 |
| Jennings TM and McDonald MJ | Esterification of the propionate groups promotes alpha/beta hemoglobin chain homogeneity of CN-hemin binding. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12054662 |
| Wardell M et al. | The atomic structure of human methemalbumin at 1.9 A. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11866438 |
| Stewart PM and Walser M | Low dose ethanol prevents propionate induced hyperammonemia. | 1981 | Biochem. Biophys. Res. Commun. | pmid:7295308 |
| Katunuma N et al. | Structure-based development of pyridoxal propionate derivatives as specific inhibitors of cathepsin K in vitro and in vivo. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10673380 |
| Nagai J et al. | Incorporation of propionate into wax esters by etiolated Euglena. | 1971 | Biochem. Biophys. Res. Commun. | pmid:5542903 |
| Bohle DS et al. | Propionic acid side chain hydrogen bonding in the malaria pigment beta-hematin. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12054752 |
| Ishii Y et al. | Preparation of EGF labeled liposomes and their uptake by hepatocytes. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2785794 |
| Cannon JB et al. | The effect of metalloporphyrins and heme liposomes on delta-aminolevulinate synthase activity in rat liver. | 1985 | Biochem. Biophys. Res. Commun. | pmid:4026834 |
| Nilsson NE et al. | Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12684041 |