propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.
To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with propionic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Rabinowitz L et al. | Effects of glucagon, insulin, propionate, acetate, and HCO3 on K excretion in sheep. | 1984 | Am. J. Physiol. | pmid:6320683 |
Clark DA et al. | Contribution of oxygen-derived free radicals to experimental necrotizing enterocolitis. | 1988 | Am. J. Pathol. | pmid:3348358 |
Williams ZR et al. | Late onset optic neuropathy in methylmalonic and propionic acidemia. | 2009 | Am. J. Ophthalmol. | pmid:19243738 |
Morrow G et al. | Propionate metabolism in fetal livers of 15 to 19 weeks' gestation. | 1975 | Am. J. Obstet. Gynecol. | pmid:1115133 |
ALTER RL et al. | The treatment of mycotic vulvovaginitis with propionate vaginal jelly. | 1947 | Am. J. Obstet. Gynecol. | pmid:20286636 |
Gilmore A et al. | Hyperamylasemia/hyperlipasemia in a child with propionic acidemia. | 2008 | Am. J. Med. Genet. A | pmid:19006211 |
Van Hove JL et al. | Cobalamin disorder Cbl-C presenting with late-onset thrombotic microangiopathy. | 2002 | Am. J. Med. Genet. | pmid:12210350 |
Van Calcar SC et al. | Case reports of successful pregnancy in women with maple syrup urine disease and propionic acidemia. | 1992 | Am. J. Med. Genet. | pmid:1481826 |
Werlin SL | E. coli sepsis as a presenting sign in neonatal propionic acidemia. | 1993 | Am. J. Med. Genet. | pmid:8357022 |
Shih VE et al. | Defective lysosomal release of vitamin B12 (cb1F): a hereditary cobalamin metabolic disorder associated with sudden death. | 1989 | Am. J. Med. Genet. | pmid:2596518 |