propionic acid

propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.

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Introduction

To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with propionic acid?

propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with propionic acid

MeSH term MeSH ID Detail
Neurotoxicity Syndromes D020258 34 associated lipids
Placenta, Retained D018457 3 associated lipids
Constipation D003248 8 associated lipids
Ileitis D007079 2 associated lipids
Carcinoma, Embryonal D018236 8 associated lipids
Parturient Paresis D010319 2 associated lipids
Ostertagiasis D010029 2 associated lipids
Ergotism D004881 4 associated lipids
Liver Abscess D008100 6 associated lipids
Dysautonomia, Familial D004402 1 associated lipids
Per page 10 20 50 100 | Total 142

PubChem Associated disorders and diseases

What pathways are associated with propionic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with propionic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with propionic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with propionic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with propionic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with propionic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with propionic acid

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Per page 10 20 50 100 | Total 6372
Authors Title Published Journal PubMed Link
Scott DA et al. Ca2+ storage in Trypanosoma brucei: the influence of cytoplasmic pH and importance of vacuolar acidity. 1995 Biochem. J. pmid:7575411
Smith RM and Osborne-White WS Synthesis of phosphoenolpyruvate from propionate in sheep liver. 1971 Biochem. J. pmid:4331860
Gaitonde MK Conversion of [U-14C]threonine into 14C-labelled amino acids in the brain of thiamin-deficient rats. 1975 Biochem. J. pmid:1180921
Biebuyck JF et al. The effects of halothane (2-bromo-2-chloro-1,1,1-trifluoroethane) on glycolysis and biosynthetic processes of the isolated perfused rat liver. 1972 Biochem. J. pmid:4344008
O'Keeffe DT and Anthony C The two cytochromes c in the facultative methylotroph Pseudomonas am1. 1980 Biochem. J. pmid:6263253
Wilkemeyer MF et al. Primary structure and activity of mouse methylmalonyl-CoA mutase. 1990 Biochem. J. pmid:1978672
Hancock FE et al. The 3H-labelling of bilirubin. 1976 Biochem. J. pmid:962882
Arinze IJ and Rowley DL Gluconeogenesis by isolated guinea-pig liver parenchymal cells. 1975 Biochem. J. pmid:177003
Ash R and Baird GD Activation of volatile fatty acids in bovine liver and rumen epithelium. Evidence for control by autoregulation. 1973 Biochem. J. pmid:4359516
Faulkner A and Turner JM Microbial metabolism of amino alcohols. Aminoacetone metabolism via 1-aminopropan-2-ol in Pseudomonas sp. N.C.I.B. 8858. 1974 Biochem. J. pmid:4362743
Young OA and Anderson JW The enzymology of short-chain fatty acyl-coenzyme A synthetase from seeds of Pinus radiata. Kinetic studies and a proposed reaction mechanism. 1974 Biochem. J. pmid:4370933
Young OA and Anderson JW Properties and substrate specificity of some reactions catalysed by a short-chain fatty acyl-coenzyme A synthetase from seeds of Pinus radiata. 1974 Biochem. J. pmid:4370976
Smith AJ and Lucas C Propionate resistance in blue-green algae. 1971 Biochem. J. pmid:5003469
Lomax MA et al. The control of fatty acid metabolism in liver cells from fed and starved sheep. 1983 Biochem. J. pmid:6615480
Evans CT et al. [13C]propionate oxidation in wild-type and citrate synthase mutant Escherichia coli: evidence for multiple pathways of propionate utilization. 1993 Biochem. J. pmid:8098211
Brass EP and Beyerinck RA Effects of propionate and carnitine on the hepatic oxidation of short- and medium-chain-length fatty acids. 1988 Biochem. J. pmid:3134008
Bell SC and Turner JM Bacterial catabolism of threonine. Threonine degradation initiated by l-threonine hydrolyase (deaminating) in a species of Corynebacterium. 1977 Biochem. J. pmid:16743051
Schwab MA et al. Secondary mitochondrial dysfunction in propionic aciduria: a pathogenic role for endogenous mitochondrial toxins. 2006 Biochem. J. pmid:16686602
Hartshorn RT and Moore GR A denaturation-induced proton-uptake study of horse ferricytochrome c. 1989 Biochem. J. pmid:2539812
Tonge P et al. Fourier-transform infra-red studies of the alkaline isomerization of mitochondrial cytochrome c and the ionization of carboxylic acids. 1989 Biochem. J. pmid:2539813
Baird GD et al. Net hepatic and splanchnic metabolism of lactate, pyruvate and propionate in dairy cows in vivo in relation to lactation and nutrient supply. 1980 Biochem. J. pmid:6989361
JAMES AT et al. The metabolism of propionic acid. 1956 Biochem. J. pmid:13382825
Malaisse WJ et al. Enzyme-to-enzyme channelling of Krebs cycle metabolic intermediates in Caco-2 cells exposed to [2-13c]propionate. 1996 Biochem. J. pmid:8760374
STORRY JE and ROOK JA EFFECT IN THE COW OF INTRARUMINAL INFUSIONS OF VOLATILE FATTY ACIDS AND OF LACTIC ACID ON THE SECRETION OF THE COMPONENT FATTY ACIDS OF THE MILK FAT AND ON THE COMPOSITION OF BLOOD. 1965 Biochem. J. pmid:14343134
Hayakawa S et al. Microbiological degradation of bile acids. Nitrogenous hexahydroindane derivatives formed from cholic acid by Streptomyces rubescens. 1976 Biochem. J. pmid:1016253
ANNISON EF et al. THE METABOLISM OF ACETIC ACID, PROPIONIC ACID AND BUTYRIC ACID IN SHEEP. 1963 Biochem. J. pmid:14063864
Hiltunen JK Metabolic effects of pent-4-enoate in isolated perfused rat heart. 1978 Biochem. J. pmid:637839
Jordan PM and Gibbs PN Mechanism of action of 5-aminolaevulinate dehydratase from human erythrocytes. 1985 Biochem. J. pmid:4004789
Gallegos AM et al. Structure and cholesterol domain dynamics of an enriched caveolae/raft isolate. 2004 Biochem. J. pmid:15149285
Hiltunen JK et al. Isolated rat heart mitochondria are able to metabolize pent-4-enoate to tricarboxylic acid-cycle intermediates. 1980 Biochem. J. pmid:7470030
Giudici TA et al. Methylmalonic and propionic acidemias: lipid profiles of normal and affected human skin fibroblasts incubated with [1-14C]propionate. 1986 Biochem. Med. Metab. Biol. pmid:2872907
Marsden D et al. Anabolic effect of human growth hormone: management of inherited disorders of catabolic pathways. 1994 Biochem. Med. Metab. Biol. pmid:7993663
Michalik M and Bryła J Inhibitory effect of gentamicin on gluconeogenesis from pyruvate, propionate, and lactate in isolated rabbit kidney-cortex tubules. 1987 Biochem. Med. Metab. Biol. pmid:3663396
Dutra JC et al. Effects of methylmalonate and propionate on uptake of glucose and ketone bodies in vitro by brain of developing rats. 1991 Biochem. Med. Metab. Biol. pmid:2015109
de Mello CF et al. Effects of methylmalonate and propionate on [3H]glutamate binding, adenylate cyclase activity and lipid synthesis in rat cerebral cortex. 1997 Biochem. Mol. Biol. Int. pmid:9305532
Larrey D et al. Effects of erythromycin on hepatic drug-metabolizing enzymes in humans. 1983 Biochem. Pharmacol. pmid:6838653
Wang H et al. Characterizing the effect of UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A9 genetic polymorphisms on enantioselective glucuronidation of flurbiprofen. 2011 Biochem. Pharmacol. pmid:21856293
Larrey D et al. Formation of inactive cytochrome P-450 Fe(II)-metabolite complexes with several erythromycin derivatives but not with josamycin and midecamycin in rats. 1983 Biochem. Pharmacol. pmid:6860368
Otagiri M et al. Binding of pirprofen to human serum albumin studied by dialysis and spectroscopy techniques. 1989 Biochem. Pharmacol. pmid:2910295
Nambi P et al. Induction of functional beta-adrenergic receptors in rat aortic smooth muscle cells by sodium butyrate. 1986 Biochem. Pharmacol. pmid:3022740
Krahenbuhl S and Brass EP Inhibition of hepatic propionyl-CoA synthetase activity by organic acids. Reversal of propionate inhibition of pyruvate metabolism. 1991 Mar 15-Apr 1 Biochem. Pharmacol. pmid:2009071
Muramatsu M et al. Enhancement of affinity to receptors in the esterified glucocorticoid, hydrocortisone 17-butyrate 21-propionate (HBP), in the rat liver. 1986 Biochem. Pharmacol. pmid:3718538
Sumegi B et al. Is there tight channelling in the tricarboxylic acid cycle metabolon? 1991 Biochem. Soc. Trans. pmid:1794455
Meharenna YT et al. Engineering ascorbate peroxidase activity into cytochrome c peroxidase. 2008 Biochemistry pmid:18771292
Shokhireva TKh et al. Assignment of heme resonances and determination of the electronic structures of high- and low-spin nitrophorin 2 by 1H and 13C NMR spectroscopy: an explanation of the order of heme methyl resonances in high-spin ferriheme proteins. 2003 Biochemistry pmid:12534280
Mileni M et al. Probing heme propionate involvement in transmembrane proton transfer coupled to electron transfer in dihemic quinol:fumarate reductase by 13C-labeling and FTIR difference spectroscopy. 2005 Biochemistry pmid:16342962
Barrows TP and Poulos TL Role of electrostatics and salt bridges in stabilizing the compound I radical in ascorbate peroxidase. 2005 Biochemistry pmid:16245922
Harada K et al. Structure and ligand binding properties of myoglobins reconstituted with monodepropionated heme: functional role of each heme propionate side chain. 2007 Biochemistry pmid:17636874
Sherman MM and Hutchinson CR Biosynthesis of lasalocid A: biochemical mechanism for assembly of the carbon framework. 1987 Biochemistry pmid:3828316
Grimshaw CE et al. Use of isotope effects and pH studies to determine the chemical mechanism of Bacillus subtilis L-alanine dehydrogenase. 1981 Biochemistry pmid:6794612