MeSH term | MeSH ID | Detail |
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Adenocarcinoma | D000230 | 166 associated lipids |
Body Weight | D001835 | 333 associated lipids |
propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.
To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with propionic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Thompson GN et al. | A simple isotopic technique for assessing vitamin responsiveness in vivo in propionic acidaemia. | 1990 | J. Inherit. Metab. Dis. | pmid:2122099 |
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Cherrington CA et al. | Short-chain organic acids at ph 5.0 kill Escherichia coli and Salmonella spp. without causing membrane perturbation. | 1991 | J. Appl. Bacteriol. | pmid:1902205 |
Nakai A et al. | Pathophysiologic study on methylmalonic aciduria: decrease in liver high-energy phosphate after propionate loading in rats. | 1991 | Pediatr. Res. | pmid:1679919 |
Davies SE et al. | Carnitine therapy and metabolism in the disorders of propionyl-CoA metabolism studied using 1H-NMR spectroscopy. | 1991 | Clin. Chim. Acta | pmid:1819469 |
Levrat MA et al. | High propionic acid fermentations and mineral accumulation in the cecum of rats adapted to different levels of inulin. | 1991 | J. Nutr. | pmid:1941180 |
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Dawson DA | Additive incidence of developmental malformation for Xenopus embryos exposed to a mixture of ten aliphatic carboxylic acids. | 1991 | Teratology | pmid:1771595 |
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Barredo MS and Evison LM | Effect of propionate toxicity on methanogen-enriched sludge, Methanobrevibacter smithii, and Methanospirillum hungatii at different pH values. | 1991 | Appl. Environ. Microbiol. | pmid:1872605 |
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Harrison PT et al. | Early changes in the forestomach of rats, mice and hamsters exposed to dietary propionic and butyric acid. | 1991 | Food Chem. Toxicol. | pmid:1874463 |
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Kleiner U et al. | [Laboratory studies of Salmonella decontamination in bone meal using propionic acid]. | 1991 | Zentralbl Hyg Umweltmed | pmid:1750967 |
Emery DG et al. | Contributions of sodium and chloride to ultrastructural damage after dendrotomy. | 1991 | Exp Brain Res | pmid:1756799 |
Henly DC and Berry MN | Relationship between the stimulation of citric acid cycle oxidation and the stimulation of fatty acid esterification and inhibition of ketogenesis by lactate in isolated rat hepatocytes. | 1991 | Biochim. Biophys. Acta | pmid:1828700 |
Grotenhuis JT et al. | Bacteriological composition and structure of granular sludge adapted to different substrates. | 1991 | Appl. Environ. Microbiol. | pmid:1892385 |
Rajagopalan R and Altekar W | Products of non-reductive CO2 assimilation in the halophilic archaebacterium Haloferax mediterranei. | 1991 | Indian J. Biochem. Biophys. | pmid:1676015 |
Byck S and Rosenblatt DS | Metabolic cooperation among cell lines from patients with inborn errors of vitamin B12 metabolism: differential response of cblC and cblD. | 1991 | Clin Invest Med | pmid:1676355 |
Kavanagh K et al. | Enhanced intraspecific protoplast fusion in yeast. | 1991 | FEMS Microbiol. Lett. | pmid:1916226 |
Weder AB et al. | Effects of lovastatin treatment on red blood cell and platelet cation transport. | 1991 | Hypertension | pmid:1991653 |
Todesco T et al. | Propionate lowers blood glucose and alters lipid metabolism in healthy subjects. | 1991 | Am. J. Clin. Nutr. | pmid:1951157 |
Barshop BA et al. | Metabolism of 1-13C-propionate in vivo in patients with disorders of propionate metabolism. | 1991 | Pediatr. Res. | pmid:1909779 |
Dutra JC et al. | Effects of methylmalonate and propionate on uptake of glucose and ketone bodies in vitro by brain of developing rats. | 1991 | Biochem. Med. Metab. Biol. | pmid:2015109 |
Vorobjeva LI et al. | Antimutagenicity of propionic acid bacteria. | 1991 | Mutat. Res. | pmid:1720873 |
Ho AK et al. | Intracellular pH on adrenergic-stimulated cAMP and cGMP production in rat pinealocytes. | 1991 | Am. J. Physiol. | pmid:1656768 |
Cherrington CA et al. | Inhibition of Escherichia coli K12 by short-chain organic acids: lack of evidence for induction of the SOS response. | 1991 | J. Appl. Bacteriol. | pmid:2019550 |
Harding BN et al. | Propionic acidaemia: a neuropathological study of two patients presenting in infancy. | 1991 | Neuropathol. Appl. Neurobiol. | pmid:1857488 |
Ferrando R | [Comparative physiology: saturated fatty acids and cholesterolemia in ruminants]. | 1991 Jun-Jul | Bull. Acad. Natl. Med. | pmid:1742626 |
Krahenbuhl S and Brass EP | Inhibition of hepatic propionyl-CoA synthetase activity by organic acids. Reversal of propionate inhibition of pyruvate metabolism. | 1991 Mar 15-Apr 1 | Biochem. Pharmacol. | pmid:2009071 |
Raisuddin S and Misra JK | Aflatoxin in betel nut and its control by use of food preservatives. | 1991 Nov-Dec | Food Addit Contam | pmid:1812017 |
Wehling M et al. | The early mineralocorticoid effector mechanism, the sodium-proton exchanger, is sensitized in lymphocytes from patients with Cushing's syndrome. | 1992 | Clin. Endocrinol. (Oxf) | pmid:1330384 |
Ho AK et al. | Intracellular pH on protein kinase C and ionomycin potentiation of isoproterenol-stimulated cyclic AMP and cyclic GMP production in rat pinealocytes. | 1992 | J. Neurochem. | pmid:1331328 |
Thomas AW et al. | Environmentally directed mutations in the dehalogenase system of Pseudomonas putida strain PP3. | 1992 | Arch. Microbiol. | pmid:1332636 |
Le Ruyet P et al. | Influence of dietary fiber and buffer value index on the ruminal milieu of lactating dairy cows. | 1992 | J. Dairy Sci. | pmid:1333496 |
Tucker WB et al. | Sodium bicarbonate or multielement buffer via diet or rumen: effects on performance and acid-base status of lactating cows. | 1992 | J. Dairy Sci. | pmid:1333497 |
Lapierre L et al. | Lithium chloride-sodium propionate agar for the enumeration of bifidobacteria in fermented dairy products. | 1992 | J. Dairy Sci. | pmid:1317893 |
Brunkhorst BA et al. | Propionate induces polymorphonuclear leukocyte activation and inhibits formylmethionyl-leucyl-phenylalanine-stimulated activation. | 1992 | Infect. Immun. | pmid:1319407 |
Bödeker D and Martens H | Elevated urinary excretion of orotic acid in sheep caused by intraruminal infusion of sodium propionate. | 1992 | Comp. Biochem. Physiol., B | pmid:1617933 |
Kalloghlian A et al. | A patient with propionic acidemia managed with continuous insulin infusion and total parenteral nutrition. | 1992 | J. Child Neurol. | pmid:1588020 |
Harrison PT | Propionic acid and the phenomenon of rodent forestomach tumorigenesis: a review. | 1992 | Food Chem. Toxicol. | pmid:1628870 |
Benjamin IJ et al. | Induction of stress proteins in cultured myogenic cells. Molecular signals for the activation of heat shock transcription factor during ischemia. | 1992 | J. Clin. Invest. | pmid:1569208 |
Deitmer JW | Evidence for glial control of extracellular pH in the leech central nervous system. | 1992 | Glia | pmid:1531809 |
Adjiri D et al. | [In vitro simulation of rabbit cecal fermentation in a semi- continuous flow fermentor. I. Role of food substrate pretreatment]. | 1992 | Reprod. Nutr. Dev. | pmid:1418397 |
Gidenne T and Bellier R | [In vivo study of cecal fermentation activity in the rabbit. Completion and validation of a new technique for cecal cannulation]. | 1992 | Reprod. Nutr. Dev. | pmid:1418398 |
Yasugi T et al. | Formic acid excretion in comparison with methanol excretion in urine of workers occupationally exposed to methanol. | 1992 | Int Arch Occup Environ Health | pmid:1487329 |
Ackermans MT et al. | Determination of propionate in bread using capillary zone electrophoresis. | 1992 | J. Chromatogr. | pmid:1487528 |
Sumegi B et al. | Regulatory consequences of organization of citric acid cycle enzymes. | 1992 | Curr. Top. Cell. Regul. | pmid:1499336 |
Van Bosterhaut B et al. | Three cases of opportunistic infection caused by propionic acid producing Corynebacterium minutissimum. | 1992 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:1396773 |
Finch L and Frederick CB | Rate and route of oxidation of acrylic acid to carbon dioxide in rat liver. | 1992 | Fundam Appl Toxicol | pmid:1426707 |
Sklan D et al. | Fatty acids, calcium soaps of fatty acids, and cottonseeds fed to high yielding cows. | 1992 | J. Dairy Sci. | pmid:1452851 |
Tung RS et al. | In vitro effects of the thiopeptide A10255 on ruminal fermentation and microbial populations. | 1992 | J. Dairy Sci. | pmid:1452854 |
Duncan G et al. | Evidence for a Na(+)-Cl(-)-H(+)-HCO3- exchange system in the mammalian lens. | 1992 | Exp. Eye Res. | pmid:1521584 |
Van Calcar SC et al. | Case reports of successful pregnancy in women with maple syrup urine disease and propionic acidemia. | 1992 | Am. J. Med. Genet. | pmid:1481826 |
Chow JC and Jesse BW | Interactions between gluconeogenesis and fatty acid oxidation in isolated sheep hepatocytes. | 1992 | J. Dairy Sci. | pmid:1401366 |
Holtug K et al. | Effects of propionate on the acid microclimate of hen (Gallus domesticus) colonic mucosa. | 1992 | Comp. Biochem. Physiol. Comp. Physiol. | pmid:1361891 |
Wilkemeyer M et al. | Propionate metabolism in cultured human cells after overexpression of recombinant methylmalonyl CoA mutase: implications for somatic gene therapy. | 1992 | Somat. Cell Mol. Genet. | pmid:1363155 |
Strobel HJ | Vitamin B12-dependent propionate production by the ruminal bacterium Prevotella ruminicola 23. | 1992 | Appl. Environ. Microbiol. | pmid:1637169 |
Ogawa K et al. | Volatile fatty acids, lactic acid, and pH in the stools of breast-fed and bottle-fed infants. | 1992 | J. Pediatr. Gastroenterol. Nutr. | pmid:1432461 |
Gamet L et al. | Effects of short-chain fatty acids on growth and differentiation of the human colon-cancer cell line HT29. | 1992 | Int. J. Cancer | pmid:1521915 |
Shoemaker JD et al. | Misidentification of propionic acid as ethylene glycol in a patient with methylmalonic acidemia. | 1992 | J. Pediatr. | pmid:1538288 |
Friedel D and Levine GM | Effect of short-chain fatty acids on colonic function and structure. | 1992 Jan-Feb | JPEN J Parenter Enteral Nutr | pmid:1738211 |
Scheppach W et al. | Effect of short-chain fatty acids on the human colonic mucosa in vitro. | 1992 Jan-Feb | JPEN J Parenter Enteral Nutr | pmid:1738218 |
Buazzi MM and Marth EH | Sites of action by propionate on Listeria monocytogenes. | 1992 Jan-Feb | Int. J. Food Microbiol. | pmid:1622747 |
McHan F and Shotts EB | Effect of feeding selected short-chain fatty acids on the in vivo attachment of Salmonella typhimurium in chick ceca. | 1992 Jan-Mar | Avian Dis. | pmid:1567301 |
Gessler NN et al. | [Effect of propionate pathway metabolites on the oxidative activity of liver mitochondria under normal conditions and in vitamin B12 deficiency]. | 1992 Jul-Aug | Prikl. Biokhim. Mikrobiol. | pmid:1528821 |
al-Hilli AL and Smith JE | Influence of propionic acid on growth and aflatoxin production by Aspergillus flavus in liquid submerged and solid substrate conditions. | 1992 Mar-Apr | J. Environ. Pathol. Toxicol. Oncol. | pmid:1573566 |
Panfili G et al. | Effect of some food preservatives on aflatoxin production. | 1992 Sep-Oct | Food Addit Contam | pmid:1298645 |
Surtees RA et al. | Neurologic outcome of propionic acidemia. | 1992 Sep-Oct | Pediatr. Neurol. | pmid:1418175 |
Winter SM et al. | Identification and comparison of the urinary metabolites of [1,2,3-13C3]acrylic acid and [1,2,3-13C3]propionic acid in the rat by homonuclear 13C nuclear magnetic resonance spectroscopy. | 1992 Sep-Oct | Drug Metab. Dispos. | pmid:1358570 |
Hurtaud C et al. | Effect of infused volatile fatty acids and caseinate on milk composition and coagulation in dairy cows. | 1993 | J. Dairy Sci. | pmid:8227627 |
Lalman DL et al. | The effects of ruminally undegradable protein, propionic acid, and monensin on puberty and pregnancy in beef heifers. | 1993 | J. Anim. Sci. | pmid:8270506 |
Anil MH et al. | Responses in the voluntary intake of hay or silage by lactating cows to intraruminal infusions of sodium acetate or sodium propionate, the tonicity of rumen fluid or rumen distension. | 1993 | Br. J. Nutr. | pmid:8329346 |
Mbanya JN et al. | The voluntary intake of hay and silage by lactating cows in response to ruminal infusion of acetate or propionate, or both, with or without distension of the rumen by a balloon. | 1993 | Br. J. Nutr. | pmid:8329347 |
Hubel KA and Russ L | Mechanisms of the secretory response to luminal propionate in rat descending colon in vitro. | 1993 | J. Auton. Nerv. Syst. | pmid:8366252 |
Schmidt JE and Ahring BK | Effects of hydrogen and formate on the degradation of propionate and butyrate in thermophilic granules from an upflow anaerobic sludge blanket reactor. | 1993 | Appl. Environ. Microbiol. | pmid:8368842 |
Wendel U et al. | Contribution of odd-numbered fatty acid oxidation to propionate production in neonates with methylmalonic and propionic acidaemias. | 1993 | Eur. J. Pediatr. | pmid:8131803 |
Schmidt H and Zerbst-Boroffka I | Recovery after anaerobic metabolism in the leech (Hirudo medicinalis L.). | 1993 | J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. | pmid:8151016 |
Rowe WA et al. | Propionate activates multiple ion transport mechanisms in the HT29-18-C1 human colon cell line. | 1993 | Am. J. Physiol. | pmid:8214077 |
Minkler PE and Hoppel CL | Quantification of free carnitine, individual short- and medium-chain acylcarnitines, and total carnitine in plasma by high-performance liquid chromatography. | 1993 | Anal. Biochem. | pmid:8214594 |
Thurman PF et al. | Possible intermediates in the biosynthesis of mycoside B by Mycobacterium microti. | 1993 | Eur. J. Biochem. | pmid:8462544 |
Russell JB and Chow JM | Another theory for the action of ruminal buffer salts: decreased starch fermentation and propionate production. | 1993 | J. Dairy Sci. | pmid:8463492 |
Farningham DA et al. | Satiety signals in sheep: involvement of CCK, propionate, and vagal CCK binding sites. | 1993 | Physiol. Behav. | pmid:8415934 |
Nègre M et al. | Microbial metabolism of fluazifop-butyl. | 1993 | J Environ Sci Health B | pmid:8409232 |
Cann IK et al. | Effects of some ionophore antibiotics and polyoxins on the growth of anaerobic rumen fungi. | 1993 | J. Appl. Bacteriol. | pmid:8444641 |
Fiems LO et al. | Effect of a viable yeast culture on digestibility and rumen fermentation in sheep fed different types of diets. | 1993 | Reprod. Nutr. Dev. | pmid:8447942 |
Hino T et al. | Effects of aibellin, a novel peptide antibiotic, on rumen fermentation in vitro. | 1993 | J. Dairy Sci. | pmid:7691910 |
Hume ME et al. | Metabolism of [14C]propionic acid in broiler chicks. | 1993 | Poult. Sci. | pmid:8502603 |