propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.
To understand associated biological information of propionic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
propionic acid is suspected in Propionic acidemia, Ischemia, Infection, Ulcerative Colitis, Alkalosis, Methylmalonic acidemia and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with propionic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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SULD HM et al. | Mechanism of formation of bile acids from cholesterol: oxidation of 5bita-choles-tane-3alpha,7alpha,12alpha-triol and formation of propionic acid from the side chain by rat liver mitochondria. | 1962 | J. Biol. Chem. | pmid:13918291 |
SIU PM and WOOD HG | Phosphoenolpyruvic carboxytransphosphorylase, a CO2 fixation enzyme from propionic acid bacteria. | 1962 | J. Biol. Chem. | pmid:13977785 |
MAZUMDER R et al. | Metabolism of propionic acid in animal tissues. IX. Methylmalonyl coenzyme A racemase. | 1962 | J. Biol. Chem. | pmid:13934211 |
BUCHANAN BB and PINE L | Characterization of a propionic acid producing actinomycete, Actinomyces propionicus, sp. nov. | 1962 | J. Gen. Microbiol. | pmid:13874228 |
HASSALL H and GREENBERG DM | Studies on the enzymic decomposition of urocanic acid. V. The formation of 4-oxoglutaramic acid, a nonenzymic oxidation product of 4(5)-imidazolone-5(4)-propionic acid. | 1963 | J. Biol. Chem. | pmid:13960897 |
HASSALL H and GREENBERG DM | The oxidation of 4(5)-imidazolone-5(4)-propionic acid to hydantoin-5-propionic acid by xanthine oxidase. | 1963 | Biochim. Biophys. Acta | pmid:13960896 |
MAZUMDER R et al. | Metabolism of propionic acid in animal tissues. X. Methylmalonyl co-enzyme A mutase holoenzyme. | 1963 | J. Biol. Chem. | pmid:13934212 |
ANNISON EF et al. | THE METABOLISM OF ACETIC ACID, PROPIONIC ACID AND BUTYRIC ACID IN SHEEP. | 1963 | Biochem. J. | pmid:14063864 |
ALLEN SH et al. | PURIFICATION AND PROPERTIES OF ENZYMES INVOLVED IN THE PROPIONIC ACID FERMENTATION. | 1964 | J. Bacteriol. | pmid:14102852 |
ABOUAKKADA AR and EL-SHAZLY K | EFFECT OF ABSENCE OF CILIATE PROTOZOA FROM THE RUMEN ON MICROBIAL ACTIVITY AND GROWTH OF LAMBS. | 1964 | Appl Microbiol | pmid:14201095 |
CANNATA JJ et al. | METABOLISM OF PROPIONIC ACID IN ANIMAL TISSUES. XII. PROPERTIES OF MAMMALIAN METHYLMALONYL COENZYME A MUTASE. | 1965 | J. Biol. Chem. | pmid:14321360 |
KAZIRO Y et al. | METABOLISM OF PROPIONIC ACID IN ANIMAL TISSUES. XI. FURTHER STUDIES ON CRYSTALLINE PROPIONYL COENZYME A CARBOXYLASE. | 1965 | J. Biol. Chem. | pmid:14256957 |
STORRY JE and ROOK JA | EFFECT IN THE COW OF INTRARUMINAL INFUSIONS OF VOLATILE FATTY ACIDS AND OF LACTIC ACID ON THE SECRETION OF THE COMPONENT FATTY ACIDS OF THE MILK FAT AND ON THE COMPOSITION OF BLOOD. | 1965 | Biochem. J. | pmid:14343134 |
Henderson TR and Jones RK | Effects of irradiation or traumatic injuries on propionate metabolism in rats. | 1971 | Clin. Chem. | pmid:4327318 |
Smith RM and Osborne-White WS | Synthesis of phosphoenolpyruvate from propionate in sheep liver. | 1971 | Biochem. J. | pmid:4331860 |
Daum RS et al. | A "new" disorder of isoleucine catabolism. | 1971 | Lancet | pmid:4143539 |
Patel MS et al. | Pathway of carbon flow during fatty acid synthesis from lactate and pyruvate in rat adipose tissue. | 1971 | J. Lipid Res. | pmid:4396562 |
Smith AJ and Lucas C | Propionate resistance in blue-green algae. | 1971 | Biochem. J. | pmid:5003469 |
Smith RF | Lactic acid utilization by the cutaneous Micrococcaceae. | 1971 | Appl Microbiol | pmid:4930285 |
Bauman DE et al. | Propionate production in the rumen of cows fed either a control or high-grain, low-fiber diet. | 1971 | J. Dairy Sci. | pmid:4937668 |
Williams DL et al. | Metabolic effects of propionate administration to normal and vitamin B12-deficient rats. | 1971 | Biochem. J. | pmid:5116531 |
Williams DL et al. | Metabolic effects of propionate in normal and vitamin B 12 -deficient rats. | 1971 | Biochem. J. | pmid:5135236 |
López Vera H | [Ibuprofen: 2-(4-isobutylphenyl) propionic acid in rheumatic patients. Preliminary report]. | 1971 | Prensa Med Mex | pmid:5140601 |
Jansen FH and Stoll MS | Separation and structural analysis of vinyl- and isovinyl-azobilirubin derivatives. | 1971 | Biochem. J. | pmid:5144760 |
Smith RM and Marston HR | Metabolism of propionate by pair-fed vitamin B12-deficient and vitamin B12-treated sheep. | 1971 | Br. J. Nutr. | pmid:5090695 |
Casteels R et al. | Electrogenic sodium pump in smooth muscle cells of the guinea-pig's taenia coli. | 1971 | J. Physiol. (Lond.) | pmid:5097601 |
Hsia YE et al. | Inherited propionyl-Coa carboxylase deficiency in "ketotic hyperglycinemia". | 1971 | J. Clin. Invest. | pmid:5101292 |
Weekes TE | Role of the rumen mucosa in the sheep: relative changes in weight, and in the ability to metabolize propionate, during pregnancy and lactation. | 1971 | Res. Vet. Sci. | pmid:5558543 |
Casteels R | The distribution of chloride ions in the smooth muscle cells of the guinea-pig's taenia coli. | 1971 | J. Physiol. (Lond.) | pmid:5579636 |
Nagai J et al. | Incorporation of propionate into wax esters by etiolated Euglena. | 1971 | Biochem. Biophys. Res. Commun. | pmid:5542903 |
Van Nevel CJ et al. | Effect of fatty acid derivatives on rumen methane and propionate in vitro. | 1971 | Appl Microbiol | pmid:5544299 |
Evans HJ and Wood HG | Purification and properties of pyruvate phosphate dikinase from propionic acid bacteria. | 1971 | Biochemistry | pmid:5544662 |
Marquardt RP | Improved method for determination of 2,2-dichloropropionic acid in chlorinated propionic acid by use of buffered mercuric nitrate solution. | 1971 Jan-Feb | J. Agric. Food Chem. | pmid:5540751 |
Vorob'eva LI et al. | [Enzymes of propionic acid fermentation on the mutant and parent forms of Propionibacterium shermanii]. | 1971 Jul-Aug | Mikrobiologiia | pmid:5096614 |
Petit JC et al. | [Hormonal therapy of advanced breast cancer with drostanolone propionate]. | 1971 Oct-Dec | Bull Cancer | pmid:4115657 |
Wiltrout DW and Satter LD | Contribution of propionate to glucose synthesis in the lactating and nonlactating cow. | 1972 | J. Dairy Sci. | pmid:5062250 |
Ando T et al. | Isolation and identification of methylcitrate, a major metabolic product of propionate in patients with propionic acidemia. | 1972 | J. Biol. Chem. | pmid:5016650 |
Baumgartner ER and Wick H | [Normal propionate metabolism in "non-ketotic hyperglycinemia"]. | 1972 | N. Engl. J. Med. | pmid:5025792 |
Williams DL and Spray GH | Metabolism of propionate in the vitamin B 12 -deficient rat. | 1972 | Br. J. Nutr. | pmid:5071687 |
Nyhan WL et al. | Tiglicaciduria in propionicacidaemia. | 1972 | Biochem. J. | pmid:5073234 |
Chan TM and Freedland RA | The effect of propionate on the metabolism of pyruvate and lactate in the perfused rat liver. | 1972 | Biochem. J. | pmid:5076196 |
Garton GA et al. | Influence of dietary volatile fatty acids on the fatty-acid composition of lamb triglycerides, with special reference to the effect of propionate on the presence of branched-chain components. | 1972 | Br. J. Nutr. | pmid:5085699 |
Firenzuoli AM et al. | [Effect of oxalate and propionate on the biosynthesis of isocitrate lyase]. | 1972 | Boll. Soc. Ital. Biol. Sper. | pmid:5032751 |
Ando T et al. | The oxidation of glycine and propionic acid in propionic acidemia with ketotic hyperglycinemia. | 1972 | Pediatr. Res. | pmid:5046977 |
Ryan JP and Ryan H | The role of intracellular pH in the regulation of cation exchanges in yeast. | 1972 | Biochem. J. | pmid:4563763 |
de Vries W et al. | Influence of oxygen on growth, cytochrome synthesis and fermentation pattern in propionic acid bacteria. | 1972 | J. Gen. Microbiol. | pmid:4647470 |
Brawand F and Walter P | [Influence of propionate on pyruvate metabolism in rat liver mitochondria]. | 1972 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:4649772 |
Pehrson B | [The effect of orally administered glycogenic substance to dairy cows. I. Na propionate, glycerol and propylene glycol to healthy, normally fed cows]. | 1972 | Nord Vet Med | pmid:4666483 |
Pehrson B | [The effect of orally administered glycogenic substance to dairy cows. II. Single oral administration of large doses of Na propionate and glycerol to healthy, starved cows and to cows with ketosis]. | 1972 | Nord Vet Med | pmid:4666484 |
Pehrson B | [The effect of orally administered glycogenic substance to dairy cows. 3. Oral treatment for ketosis with a combination of Na propionate, glycerol and propylene glycol in moderate doses]. | 1972 | Nord Vet Med | pmid:4666485 |